This study examined smoking patterns, depression, and socio-demographic factors in Flemish women during pregnancy and postpartum. The study found: 1) Smokers and initial smokers reported higher depressive symptoms during and after pregnancy than recent ex-smokers or non-smokers, independent of education level. 2) Depressive symptoms decreased after pregnancy for most groups except low-educated smokers, whose symptoms remained high. 3) Ex-smokers and initial smokers were most likely to have smoking partners, indicating a need for partner involvement in smoking cessation support.