This document outlines a presentation on good clinical research given at a conference in Istanbul, Turkey in June 2013. It discusses why good medical research is important, how to conduct research properly, and ways to improve the quality of clinical research. Key points include asking the right research question, using proper study designs, publishing results transparently, and sharing responsibility across all stakeholders to maximize the benefits of clinical research. The overall goal is to ensure research answers relevant questions and leads to improvements in patient care and outcomes.
Atul Butte's presentation to the Association of Medical School Pediatric Department Chairs #AMSPDC on March 3, 2018.
Some pre-publication data slides have been removed from this deck.
Atul Butte's presentation to the Association of Medical School Pediatric Department Chairs #AMSPDC on March 3, 2018.
Some pre-publication data slides have been removed from this deck.
Clinical Practice Guidelines initiative by the Healthcare Quality Directorate of the Alexandria University Hospitals, Alexandria, Egypt. For further details please refer to http://onlinelibrary.wiley.com/doi/10.1111/jep.12479/full
Developing a PLN and open co-learning opportunities #UoRsocialmediaSue Beckingham
Developing your academic online presence with social media
Workshop at the University of Reading led by Sue Beckingham SFHEA, Senior Lecturer in Information Systems and LEAD Associate at Sheffield Hallam University, this workshop will provide an opportunity to learn about new approaches and practical examples of using social media in higher education; and as co-learners share examples of effective practice and consider how these might be applied in your own contexts. The session will also provide participants some time and space to network and potentially make new connections.
The workshop aims to provide participants with an opportunity to:
Gain a better understanding of how social media can be used in a scholarly context
Appreciate the value of developing a rich professional online presence
Learn about opportunities for social and open informal learning through social media
Appreciate five elements of ‘working out loud’ (Stepper 2015) and how these can be of value to both yourself and others
Using the 5C Framework (Nerantzi and Beckingham 2014, 2015) as a lens we will consider how social media can be used to connect, communicate, curate, collaborate and create. In doing so consider the value of:
Developing a digital professional persona to share scholarly achievements
Cultivating your own personal learning network and co-learning communities
Sharing learning journeys through working out loud
Programme
Tuesday 26 April 2016
10.45-11.00 Networking and registration
11.00-12.30 Becoming a Digital Scholar using social media
12.30-13.15 Lunch
13.15 -14.30 Developing a PLN and open co-learning opportunities
Clinical Practice Guidelines initiative by the Healthcare Quality Directorate of the Alexandria University Hospitals, Alexandria, Egypt. For further details please refer to http://onlinelibrary.wiley.com/doi/10.1111/jep.12479/full
Developing a PLN and open co-learning opportunities #UoRsocialmediaSue Beckingham
Developing your academic online presence with social media
Workshop at the University of Reading led by Sue Beckingham SFHEA, Senior Lecturer in Information Systems and LEAD Associate at Sheffield Hallam University, this workshop will provide an opportunity to learn about new approaches and practical examples of using social media in higher education; and as co-learners share examples of effective practice and consider how these might be applied in your own contexts. The session will also provide participants some time and space to network and potentially make new connections.
The workshop aims to provide participants with an opportunity to:
Gain a better understanding of how social media can be used in a scholarly context
Appreciate the value of developing a rich professional online presence
Learn about opportunities for social and open informal learning through social media
Appreciate five elements of ‘working out loud’ (Stepper 2015) and how these can be of value to both yourself and others
Using the 5C Framework (Nerantzi and Beckingham 2014, 2015) as a lens we will consider how social media can be used to connect, communicate, curate, collaborate and create. In doing so consider the value of:
Developing a digital professional persona to share scholarly achievements
Cultivating your own personal learning network and co-learning communities
Sharing learning journeys through working out loud
Programme
Tuesday 26 April 2016
10.45-11.00 Networking and registration
11.00-12.30 Becoming a Digital Scholar using social media
12.30-13.15 Lunch
13.15 -14.30 Developing a PLN and open co-learning opportunities
Book review of "Child of the dark" by Carolina Maria de Jesus. The incredible survival story of a mother and her children that opened the eyes of the world to the plight of the poor in 3rd world countries.
Apple Days - A 1980’s perspective of Apple UKGary Potter
I felt like Billy Elliot, coming from a working class, industrial town in the Black Country,
I had very little knowledge of micro electronics and only an awareness of what an Apple Personal Computer could do.
Arrogant Bastards Guide to Cloud Architectureevilmartini
Clouds are different
We all know this, but we continually build applications like it's not the case? We should be smarter than this, but we're not.
So it's time to get all opinionated about building a cloud application.
Career is an important aspect of a working person's life, but, health is even more important. We at CareerBuilder India bring to you the facts about Health & Career so you can maintain a balance between Career and Health.
Read more interesting content, at http://www.thecareermuse.co.in/ - We intend to inform and inspire recruiters, job seekers and anyone with an interest in the workplace and HR technology.
Hope you enjoyed reading the Infographic.
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How the Internet of Things Leads to Better, Faster Crisis CommunicationBlackBerry
The Internet of Things promises to provide a wide range of futuristic benefits, but what is often overlooked is how deeply IoT sensors and data analytics already impact how we live and how we conduct business. This is especially true of crisis communications. Here, IoT has far-reaching implications, both in the present and in the future.
This whitepaper explores how IoT sensors powerfully expand the capabilities of networked crisis communication solutions. It also discusses typical scenarios for incorporating IoT sensor data within emergency preparedness scenarios. Finally, it demonstrates why AtHoc is particularly well suited for using IoT data to deliver faster, more accurate situational awareness in an intuitive manner, without inundating employees with excess data or forcing emergency management staff to become data scientists.
Creative Humanitarian Approaches To Poverty Alleviation And Sustainability: E...Dr. Chris Stout
This was an invited presentation for the Inaugural Thought Leaders Conference in 2016 for the Academy for Overcoming Global Poverty.
This presentation will begin by addressing the diseases of poverty from a global health perspective. Examples and statistical data will then give way to a number of stories about various humanitarian organizations that are as innovative in their approach as they are successful in their outcomes. Inspirational stories as well as practical tools will round out this rich and engaging presentation.
The embedded links may not work in SlideShare, so please feel free to email me for a copy at DrChrisStout@gmail.com and/or to be added to our email list.
You can join our Facebook Group and interact with over 21000 likeminded individuals at: https://www.facebook.com/groups/CenterForGlobalInitiatives/
And if you’d like to support the Center’s work with a tax deductible donation, that would be fantastic(!) and do a great deal: http://centerforglobalinitiatives.org/donateNow.cfm
Cheers, and thank you for your work,
Chris
Http://CenterForGlobalInitiatives.org
STARSurg: The first student-led collaborativeSTARSurg
STARSurg is the first student-led collaborative to form. This UK based network of medical students, only a year old has managed to deliver a multi-centre national project, and is inviting medical students from the UK and Ireland to take part!
To find out more, please read these slides and visit www.starsurg.org
You can also email us at collaborate@starsurg.org
Involving People: Patients, Participants & Consumers in U.K.Cancer Research (...Nowgen
Involving People: Patients, Participants & Consumers in U.K.Cancer Research, presented by Richard Stephens at the EUPATI-UK Network Conference on 6 March 2014 in Leeds, UK
An Overview on Evidence-Based Clinical Guidelines for the Staff of the NICU of King Saud Medical City Presented in Wednesday March 20th, 2013 in Riyadh, KSA by Dr. Yasser Sami Amer
Participants: Dr Nabil AlOthaidan, Dr Haider Sumaily, Dr Tarek Abo ElMaaty, Dr Mohamed Jaaffar, Dr Samer Askoul, Dr Kussai Awad, Dr Angelito Narito, Dr Faiza Gaber, Dr Eiman Darwish, Dr Sharifa Alassiri. Michael Randy, Shanon and Dr Yazid, Dr Omnia, Dr Alaa and Dr Titiana and the respectable staff of the NICU in KSMC.
Special Thanks to Miss Nawf El-Noumsy for organization
Data gathering | Primary data collection | Healthcare blockchainPubrica
The objective outlined in this essay is to investigate the condition of interstitial cystitis as a
study topic, develop a research question and project goal, and explain three potential
methodologies. The gathering and administration of data collection important to the project
will be highlighted. The writer will critically evaluate the benefits and drawbacks of each
approach regarding the chosen topic and the ethical difficulties and considerations for each
methodological approach.
Read more @ https://pubrica.com/services/medical-data-collection/
Visit us @ https://pubrica.com/insights/sample-work/medical-data-collection-on-interstitial-cysts-and-drug-uracysts/
STARSurg - student audit and research collaboration presentationDr Edward Fitzgerald
The Student Audit and Research in Surgery Collaborative (STARSurg) is the UK’s first national student-led research collaborative. STARSurg empowers students from all 33 medical schools in the UK to participate in high quality national audit and research studies in surgery which aim to improve patient care.
STARSurg fosters academic and research training, promotes evidence-based practice and builds a culture of collaboration necessary for 21st century medicine.
STARSurg continues to grow nationally and has since delivered three multi-centre and student-led national studies, which to date have included thousands of collaborators and over ten thousand patients across the UK and Ireland.
A presentation given during the orientation day (Sept 11, 2011) for UQUDENT students to go through the different learning resources at Umm Al-Qura University.
EVB-Evidence Based Practice- principles,purposes,valuechristenashantaram
This brief out the principles,purposes,value involved in EVB-Evidence Based Practice and helps health, scoial care practisioner to know more about the EVB-Evidence Based Practicein health and scocial care international base.
MedicReS Conference 2017 Istanbul - Fostering Responsible Conduct of Research...MedicReS
Fostering Responsible Conduct of Research
MedicReSConference
May 5, 2017
Istanbul, Turkey
Adil E. Shamoo, Ph.D., CIP
University of Maryland School of Medicine
MedicReS Conference 2017 Istanbul - Ethical issues of secondary analysis of a...MedicReS
Ethical issues of secondary analysis of archived data
MedicReS Conference
May 4, 2017
Istanbul, Turkey
Adil E. Shamoo, Ph.D., CIP
University of Maryland School of Medicine
MedicReS Conference 2017 Istanbul - Integrity of Authorship in Research Publi...MedicReS
Integrity of Authorship in Research Publications
MedicReSConference
May 4, 2017
Istanbul, Turkey
Adil E. Shamoo, Ph.D., CIP
University of Maryland School of Medicine
MedicReS Winter School 2017 Vienna - Ethics of Cancer Trials - Adil E. ShamooMedicReS
A Comprehensive Introduction to the Ethical Issues at stake in the conduct of Cancer Research
Adil E. Shamoo, Ph.D.
University of Maryland School of Medicine
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
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CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...
Justin Davis - MedicReS World Congress 2013
1. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Why Good Medical Research?
Dr Justine Davies
Executive editor
The Lancet
7. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Clinical research spending
• $160 billion per year on biomedical research
• About 1/3 of this is on clinical research
• In the US the total spend is around $100
billion
• About half of spend is on clinical research
8. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Clinical research funding in the UK
• approx £3 billion per year
• 1/3 of medical research funding (£1078
million per year) comes from charities
• 60% of this money comes from individuals
10. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
• The key question is ‘how’ to do good medical
research
• To answer this, one must first consider what
good medical research is
11. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Good medical research
answers a relevant question
• The AIM of the research is paramount
• The study design should allow for the question
to be answered
• Leaving as few doubts as possible
• Or leading to a plan for further research
12. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Number of clinical trials
• Clinical trials.gov:
• 150,000 trials
• 185 countries
• US is largest single area
13. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Other clinical trials
registration databases
• Pan African Clinical Trials Registry
• Australia and New Zealand Clinical Trials
Registry
• Brazilian Clinical Trials Registry
• ..........
14. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
“85% of research is
wasteful or inefficient”
15. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Figure
Source: The Lancet 2009; 374:86-89 (DOI:10.1016/S0140-6736(09)60329-9)
16. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Asking the wrong question
This is the wrong time to be asking ‘why was this done?’!
17. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
The wrong question
• Of no use to patients (OA)
• Question has already been answered
• Proxy measures that don’t translate into
reliable clinical outcomes
• Time frame for grant won’t allow assessment
of relevant outcomes
18. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Poor or inferior design
• Non blinded rct when could be blinded
• No power calculation
• Incorrect power calculation
• Outcome measures not validated
• Poor quality studies in meta-analyses
• Retrospective vs prospective cohort
19. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Research not published
• Positive reporting bias
• Negative studies go unpublished
• Idea is never ‘put to bed’
20. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Biased reports
• Spin
• Negative trials reported as positive
• ‘trends’ emphasised
• Secondary outcomes over hyped
• Subgroup analyses over hyped
21. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
When the research gets to an editor’s in-box, it
is too late
22. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
How to get better!
• Researchers
• Authors
• Funders
• Reviewers
• Editors
• Publishers
• Readers
• Shared responsibility!
23. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Researchers and authors
24. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Ask the right question
• GET OUT OF THE LAB!
• See the outside world
• Ask the patients what is important
• THINK LIKE AN EDITOR/REVIEWER
25. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Use the right design
• THINK LIKE AN EDITOR/REVIEWER!
• Write the paper before you write the grant
• Ask – will my methods give me an answer to
my question
• Go see a statistician (worth their weight in
gold!)
26. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Protocol
• SPIRIT guidelines for protocol
28. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Trial registration
• ICJME
• The Lancet will only consider trials that are
registered before recruitment of the first
patient (The Lancet, May 2005)
31. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Ethics
• Doing a study in a way that will provide useful
results
• Follow the protocol
• Ethics approval
• Patient consent
• Patient confidentiality
32. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Throughout the study
• Make every effort to recruit the required
number of patients
• Be meticulous
• Record data correctly
• Stick to the rules
• Don’t take short cuts
33. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Publish it
• Ensure dissemination of results
• Aim high (easier if previous steps have been
taken)
• Discuss results at conferences
35. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
What journals want
to know: IMRaD
• Introduction - Why did you do it?
• Methods - What did you do?
• Results - What did you find?
• Discussion – What might it mean.
• Abstract
36. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Reporting guidelines
Check journal websites
CONSORT (RCT)
STROBE (cohort, case-control, cross-sectional)
PRISMA (systematic reviews and meta)
STARD (diagnostic accuracy reporting)
37. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Make it apparent to the editor (cover letter?)
• What is the overall finding?
• What are the strength and weaknesses?
• Why might the results be different from
previous research?
• What might the study mean for clinicians or
policy makers?
• What questions remain unanswered?
• What next?
41. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Journals
42. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Publication ethics
• Authorship (what constitutes authorship)
• Author conflict of interest
• Role of the funding source
• Plagiarism and text recycling
• (Research misconduct)
43. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Inappropriate authorship
or non-authorship
The 3G’s
• Guests (invites him/herself)
• Gifts (authorship as a present – ie department
head...)
• Ghosts (or the disappearing author.....)
44. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Conflict of interest
ICJME definition
“Conflict of interest for a given manuscript exists
when a participant in the peer review and
publication process – author, reviewer, or editor –
has ties to activities that could inappropriately
influence his/her judgment, WHETHER OR NOT
JUDGMENT IS IN FACT AFFECTED”
45. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
• Exists since 2008 (CrossRef, uses iThenticate)
• >126 publishers signed up (>50 000 journals)
• >25 Mio pieces of scientific literature in
database
• Takes test-text and matches it with published
pieces (does not check images, figures, or
tables)
plagiarism, duplicate publication,
and ‘self-plagiarism’
46. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
• Ensure guidelines are adhered to
• Uphold standards (plagiarism, etc)
• Full and transparent peer review
• Expediency
• Research in context (comments)
• Education
• Approachability
47. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Research in context
What does it add?
51. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Funders
52. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Open access?
53. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
• Take a longer term view
• Consult with patients
• Consult with physicians
• Make the process easier for applicants
MedicReS Good Clinical Research CME
June 6-7 2013 | Istanbul Turkey
54. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Research in an ideal world
Evidence of how to implement
intervention in practice
Large-scale trial evidence that
intervention works
Small-scale RCT evidence of
efficacy
Preclinical evidence of
intervention effect
Robust understanding of
disease pathology and risk
factors
Good understanding of normal
physiology
55. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Research in reality...
56. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
Why good clinical research?
• Save the world
• Relieve suffering
• Improve society
• Help individuals
• Reduce pain
57. MedicReS Good Clinical Research CME
June 7-8 2013 | Istanbul Turkey
How good medical research
Copyright: Scoutsandstilettoes