Jonas Salk was an American medical researcher and virologist best known for developing the first successful polio vaccine in the 1950s. He was born in 1914 in New York and studied at public schools before earning his medical degree. Salk spent his career researching viruses and vaccines, developing the first influenza vaccine and then focusing on conquering polio. Through clinical trials in the 1950s, Salk's inactivated polio vaccine was found to be safe and effective, virtually eradicating the disease in the United States and many other countries. For this achievement, Salk became a celebrated medical pioneer but remained humble, dedicated to scientific research for improving human life. He continued working to develop vaccines for other diseases until his
Jonas Salk was born in 1914 in New York City and invented the first successful polio vaccine in 1955 after years of work, helping to nearly eradicate the disease. He founded the Salk Institute in La Jolla, California in 1960 to continue vaccine research and biological study.
Robert Koch was a German physician who made groundbreaking discoveries in microbiology. He isolated the bacteria that cause anthrax, tuberculosis, and cholera. Koch developed Koch's postulates, a set of criteria for establishing causation between a microorganism and a disease. He was awarded the Nobel Prize in Physiology or Medicine in 1905 for his tuberculosis findings. Koch helped establish the field of microbiology and inspired other major figures through his research methods.
Alexander Fleming was a Scottish bacteriologist born in 1881 who is renowned for discovering the antibiotic penicillin. He attended schools in Scotland and London before becoming a bacteriologist. In 1928, Fleming discovered that a mold in one of his culture plates was preventing the growth of bacteria, which led him to realize penicillin's potential as an antibiotic. Penicillin is a natural substance produced by mold that is highly effective in fighting bacterial infections. Fleming's discovery of penicillin revolutionized modern medicine and saved countless lives by providing an effective treatment for bacterial diseases. He spent the rest of his career studying penicillin and died in 1955.
NAME
Albert Einstein
PLACE OF BIRTH
March 14 1879
Ulm, Württemberg, Germany
OCCUPATION
Physicist , Scientist
EDUCATION
Luitpold Gymnasium , Eidgenossische Polytechnische Schule (Swiss Federal Polytechnic School)
PLACE OF DEATH
April 18, 1955
Princeton, New Jersey
Robert Koch was a German scientist in the late 19th century who made breakthroughs in understanding deadly diseases like cholera and tuberculosis. Through careful microscopic study using stains and photography, he discovered that specific microbes caused specific diseases, identifying the bacteria that caused tuberculosis in 1882 and cholera in 1883. His scientific evidence that microbes spread disease helped reform public health and prevention efforts, establishing the new field of modern bacteriology.
Robert Koch was a German physician and microbiologist who made groundbreaking contributions to the field of bacteriology. He discovered the anthrax bacillus, tuberculosis bacillus, and cholera vibrio, and developed techniques for isolating and growing bacteria in pure cultures. Koch also formulated systematic principles known as Koch's postulates to establish causative relationships between microbes and diseases. During his career, he held professorships at Berlin University and directed the Institute for Infectious Diseases, making important discoveries related to cholera, tuberculosis, and malaria. Koch received many honors for his work, including the Nobel Prize in Physiology or Medicine in 1905.
This is a comprehensive endeavour regarding the Early Life & Education, Personal Life, Academic, & Scientific Career, Awards & Honors, and Publications of Albert Einstein
Jonas Salk was born in 1914 in New York City and invented the first successful polio vaccine in 1955 after years of work, helping to nearly eradicate the disease. He founded the Salk Institute in La Jolla, California in 1960 to continue vaccine research and biological study.
Robert Koch was a German physician who made groundbreaking discoveries in microbiology. He isolated the bacteria that cause anthrax, tuberculosis, and cholera. Koch developed Koch's postulates, a set of criteria for establishing causation between a microorganism and a disease. He was awarded the Nobel Prize in Physiology or Medicine in 1905 for his tuberculosis findings. Koch helped establish the field of microbiology and inspired other major figures through his research methods.
Alexander Fleming was a Scottish bacteriologist born in 1881 who is renowned for discovering the antibiotic penicillin. He attended schools in Scotland and London before becoming a bacteriologist. In 1928, Fleming discovered that a mold in one of his culture plates was preventing the growth of bacteria, which led him to realize penicillin's potential as an antibiotic. Penicillin is a natural substance produced by mold that is highly effective in fighting bacterial infections. Fleming's discovery of penicillin revolutionized modern medicine and saved countless lives by providing an effective treatment for bacterial diseases. He spent the rest of his career studying penicillin and died in 1955.
NAME
Albert Einstein
PLACE OF BIRTH
March 14 1879
Ulm, Württemberg, Germany
OCCUPATION
Physicist , Scientist
EDUCATION
Luitpold Gymnasium , Eidgenossische Polytechnische Schule (Swiss Federal Polytechnic School)
PLACE OF DEATH
April 18, 1955
Princeton, New Jersey
Robert Koch was a German scientist in the late 19th century who made breakthroughs in understanding deadly diseases like cholera and tuberculosis. Through careful microscopic study using stains and photography, he discovered that specific microbes caused specific diseases, identifying the bacteria that caused tuberculosis in 1882 and cholera in 1883. His scientific evidence that microbes spread disease helped reform public health and prevention efforts, establishing the new field of modern bacteriology.
Robert Koch was a German physician and microbiologist who made groundbreaking contributions to the field of bacteriology. He discovered the anthrax bacillus, tuberculosis bacillus, and cholera vibrio, and developed techniques for isolating and growing bacteria in pure cultures. Koch also formulated systematic principles known as Koch's postulates to establish causative relationships between microbes and diseases. During his career, he held professorships at Berlin University and directed the Institute for Infectious Diseases, making important discoveries related to cholera, tuberculosis, and malaria. Koch received many honors for his work, including the Nobel Prize in Physiology or Medicine in 1905.
This is a comprehensive endeavour regarding the Early Life & Education, Personal Life, Academic, & Scientific Career, Awards & Honors, and Publications of Albert Einstein
Alexander Fleming was born in 1881 in Lochfield, Scotland. He studied medicine in London and served as a doctor in World War I. In 1928, he discovered penicillin after observing that a fungus in his laboratory, Penicillium notatum, killed surrounding bacteria. He discovered that penicillin was an effective antibiotic that could cure previously incurable diseases caused by bacteria. Fleming received the Nobel Prize in 1945 for his discovery of penicillin, which revolutionized medicine.
Eudora Welty was an American author born in 1909 in Jackson, Mississippi. She was influenced by her educated parents and attended college in Mississippi and Wisconsin, graduating with a Bachelor's in Arts in 1929. Welty published drawings and writings throughout the 1920s and 1930s before releasing her first book of short stories in 1941. She published numerous short stories and novels throughout her career and received many honors, including a Pulitzer Prize and Presidential Medal of Freedom. Welty died in Jackson in 2001 at the age of 92.
The document provides information from a presentation on pandemic influenza planning and preparedness. It defines pandemic influenza and describes factors that cause pandemics. It discusses past pandemics like the 1918 Spanish Flu pandemic. It also addresses the current threat of influenza, describing seasonal flu, avian flu, and the possibility of another influenza pandemic.
Alexander Fleming was a Scottish biologist and pharmacologist best known for discovering the antibiotic substance penicillin in 1928. He shared the Nobel Prize in Physiology or Medicine in 1945 with Howard Florey and Ernst Chain for this discovery. Fleming devoted his career to investigating the human body's defenses against bacterial infections and made two important discoveries: the enzyme lysozyme in 1923 and penicillin in 1928. Penicillin became one of the most powerful discoveries to treat bacterial infections and revolutionized modern medicine.
Alexander Fleming was a Scottish biologist and pharmacologist who accidentally discovered penicillin in 1928. While searching for antibacterial agents after World War I, Fleming noticed that a fungus in one of his staphylococci cultures had destroyed the surrounding bacteria. He identified the fungus as Penicillium and the substance it produced as penicillin. Although Fleming struggled to develop penicillin further, his discovery later helped scientists Howard Florey and Ernst Chain purify and mass produce penicillin during World War II, saving countless lives. Fleming received widespread recognition for his discovery, including the 1945 Nobel Prize in Physiology or Medicine.
Dr. Chitra Bhattacharya will be teaching a course on fundamentals of microbiology. The course will cover terminology, identification, why microbiology is studied, its history and contributions of key figures. It will discuss the omnipresence of microbes in nature and introduce concepts like microbiology, microorganisms, and microscopy. The history will be divided into the discovery, transitional, golden and modern eras highlighting figures like Aristotle, Van Leeuwenhoek, Pasteur and Fleming. The document provides definitions of key terms and an overview of the scope and content to be covered in the course.
- The document discusses the history and scope of microbiology, from early observations of microorganisms in the 1600s to modern discoveries and applications.
- Key figures mentioned include Anton van Leeuwenhoek, who first observed microbes under a microscope, Louis Pasteur who disproved spontaneous generation and established germ theory, and Robert Koch who developed techniques for growing pure cultures of bacteria.
- Microbiology now encompasses the study of bacteria, fungi, viruses, and their roles in medicine, industry, biotechnology, and the environment.
A biographical ppt providing a complete account of the life and times of Albert Einstein including his childhood,major achievements and controversies,etc
J. C. Bose in scientific and national contextsRajeshKochhar4
J C Bose was the first tangible proof that members of a slave country could be the equals of their European masters. Bose and P C Ray were India’s (and non-Western world’s) first mainstream modern scientists. Both burst on the world scene in 1895.
Henrietta Lacks' cells were taken without her permission in 1951 and used to create the first immortal human cell line, known as HeLa cells. Her cells have been vital to many medical advances but her family received no compensation. This raises questions about informed consent and who should benefit from medical research using patients' cells. While laws now require permission, Henrietta Lacks' case highlighted the need for clear bioethical guidelines regarding human tissue research and its commercial applications.
Stephen Hawking was a renowned English theoretical physicist and cosmologist born in 1942 in Oxford, England. He suffered from amyotrophic lateral sclerosis, becoming almost completely paralyzed, yet made groundbreaking contributions to the fields of cosmology and quantum gravity. Some of his most notable works include collaborating with Roger Penrose on gravitational singularity theorems and predicting that black holes emit radiation. He was also a bestselling author and subject of films that helped raise his public profile as a scientist.
Edward Jenner was born in 1749 in England and is known as the father of immunology. He discovered the cure for smallpox through observing that milkmaids who had previously contracted cowpox did not get smallpox. Jenner hypothesized that cowpox could be used to cure smallpox. Through experimenting by using cowpox as a vaccination for smallpox, he found his hypothesis to be true. His discovery of vaccination led to vaccines becoming common and saving millions of lives worldwide.
Stephen Hawking was a renowned theoretical physicist and cosmologist born in England in 1942. He studied physics and cosmology at Oxford and Cambridge universities. Hawking was diagnosed with ALS at age 21 but defied the odds to survive for over 50 years with the disease, which left him paralyzed. Despite his disability, he was able to continue his groundbreaking research on black holes and the origins of the universe. Some of his major contributions include developing the theory of Hawking radiation and showing how black holes can emit particles. He also helped develop links between gravity and quantum mechanics. Hawking authored several popular science books and was awarded numerous honors for his scientific achievements, including the Presidential Medal of Freedom.
Robert Koch was a German physician and scientist who is considered one of the founders of bacteriology. He developed experimental techniques to isolate bacteria and prove they cause specific diseases, such as showing that Bacillus anthracis causes anthrax. Koch established four steps, known as Koch's postulates, to identify the microorganisms that cause diseases. His work helped prove the germ theory of disease and led to advances in combating disease through isolation of pathogens like anthrax, tuberculosis, and cholera.
This document provides an overview of bioterrorism. It begins with definitions of bioterrorism and a brief history of biological weapons use. It then describes various biological agents that could potentially be used for bioterrorism, classified by the CDC into Categories A, B, and C based on their ease of transmission and potential to cause harm. The document discusses India's existing preparedness measures against bioterrorism and the roles of dentists. It emphasizes the importance of prevention, early detection, and treatment in combating bioterrorism. Laboratories play a key role in the detection and identification of biological agents.
Barack Obama was born in 1961 in Hawaii to a Kenyan father and American mother. He graduated from Columbia University and Harvard Law School, then worked as a civil rights attorney and law professor. Obama was elected to the Illinois State Senate in 1996 and U.S. Senate in 2004, becoming the first African American president in 2008. As president, Obama signed economic stimulus bills and health care reform legislation while dealing with wars in Iraq and Afghanistan.
Stephen Hawking was born in 1942 in Oxford, England. He studied physics and cosmology at Oxford and Cambridge. He was diagnosed with ALS at age 21 but survived far longer than doctors predicted. Hawking made groundbreaking contributions to theoretical physics and cosmology, including proving that black holes emit radiation and theorizing about the origins and eventual end of the universe. He authored the popular science book "A Brief History of Time" and received numerous honors. Hawking continued his research despite being paralyzed and communicating through computers until his death in 2018.
Stephen Hawking was a renowned physicist and author who overcame amyotrophic lateral sclerosis (ALS) to make groundbreaking contributions to the fields of cosmology and physics. He had a normal childhood but was later diagnosed with ALS, a neurodegenerative disease. Despite his illness, he completed his PhD at Cambridge and had a successful career, making predictions about black holes and the origin of the universe. Hawking worked diligently throughout his life to advance scientific knowledge.
Introduction to bioterrorism , history of bioterrorism, key features of biological agents used as bioweapons, biological agents and effects, bioterrorism agents, effects of biological attacks, COVID-19 used as bioweapon , technology at work, preventive measures.
Jonas Salk was an American physician born in 1914 who developed the first successful polio vaccine in 1947 while director of virus research at the University of Pittsburgh. He discovered the vaccine for polio which dramatically transformed public health by preventing future cases of the disease with no detected side effects, earning him awards like the Lasker award.
The document discusses the history and development of the polio vaccine. It describes how the polio vaccine was created to prevent polio, a viral disease that causes paralysis. There are two main types of polio vaccines - the inactivated polio vaccine (IPV) developed by Jonas Salk, and the oral polio vaccine (OPV) developed by Albert Sabin. The IPV uses dead virus and is administered via injection, while the OPV uses live attenuated virus and is taken orally. Widespread use of polio vaccines has nearly eradicated the disease globally.
Alexander Fleming was born in 1881 in Lochfield, Scotland. He studied medicine in London and served as a doctor in World War I. In 1928, he discovered penicillin after observing that a fungus in his laboratory, Penicillium notatum, killed surrounding bacteria. He discovered that penicillin was an effective antibiotic that could cure previously incurable diseases caused by bacteria. Fleming received the Nobel Prize in 1945 for his discovery of penicillin, which revolutionized medicine.
Eudora Welty was an American author born in 1909 in Jackson, Mississippi. She was influenced by her educated parents and attended college in Mississippi and Wisconsin, graduating with a Bachelor's in Arts in 1929. Welty published drawings and writings throughout the 1920s and 1930s before releasing her first book of short stories in 1941. She published numerous short stories and novels throughout her career and received many honors, including a Pulitzer Prize and Presidential Medal of Freedom. Welty died in Jackson in 2001 at the age of 92.
The document provides information from a presentation on pandemic influenza planning and preparedness. It defines pandemic influenza and describes factors that cause pandemics. It discusses past pandemics like the 1918 Spanish Flu pandemic. It also addresses the current threat of influenza, describing seasonal flu, avian flu, and the possibility of another influenza pandemic.
Alexander Fleming was a Scottish biologist and pharmacologist best known for discovering the antibiotic substance penicillin in 1928. He shared the Nobel Prize in Physiology or Medicine in 1945 with Howard Florey and Ernst Chain for this discovery. Fleming devoted his career to investigating the human body's defenses against bacterial infections and made two important discoveries: the enzyme lysozyme in 1923 and penicillin in 1928. Penicillin became one of the most powerful discoveries to treat bacterial infections and revolutionized modern medicine.
Alexander Fleming was a Scottish biologist and pharmacologist who accidentally discovered penicillin in 1928. While searching for antibacterial agents after World War I, Fleming noticed that a fungus in one of his staphylococci cultures had destroyed the surrounding bacteria. He identified the fungus as Penicillium and the substance it produced as penicillin. Although Fleming struggled to develop penicillin further, his discovery later helped scientists Howard Florey and Ernst Chain purify and mass produce penicillin during World War II, saving countless lives. Fleming received widespread recognition for his discovery, including the 1945 Nobel Prize in Physiology or Medicine.
Dr. Chitra Bhattacharya will be teaching a course on fundamentals of microbiology. The course will cover terminology, identification, why microbiology is studied, its history and contributions of key figures. It will discuss the omnipresence of microbes in nature and introduce concepts like microbiology, microorganisms, and microscopy. The history will be divided into the discovery, transitional, golden and modern eras highlighting figures like Aristotle, Van Leeuwenhoek, Pasteur and Fleming. The document provides definitions of key terms and an overview of the scope and content to be covered in the course.
- The document discusses the history and scope of microbiology, from early observations of microorganisms in the 1600s to modern discoveries and applications.
- Key figures mentioned include Anton van Leeuwenhoek, who first observed microbes under a microscope, Louis Pasteur who disproved spontaneous generation and established germ theory, and Robert Koch who developed techniques for growing pure cultures of bacteria.
- Microbiology now encompasses the study of bacteria, fungi, viruses, and their roles in medicine, industry, biotechnology, and the environment.
A biographical ppt providing a complete account of the life and times of Albert Einstein including his childhood,major achievements and controversies,etc
J. C. Bose in scientific and national contextsRajeshKochhar4
J C Bose was the first tangible proof that members of a slave country could be the equals of their European masters. Bose and P C Ray were India’s (and non-Western world’s) first mainstream modern scientists. Both burst on the world scene in 1895.
Henrietta Lacks' cells were taken without her permission in 1951 and used to create the first immortal human cell line, known as HeLa cells. Her cells have been vital to many medical advances but her family received no compensation. This raises questions about informed consent and who should benefit from medical research using patients' cells. While laws now require permission, Henrietta Lacks' case highlighted the need for clear bioethical guidelines regarding human tissue research and its commercial applications.
Stephen Hawking was a renowned English theoretical physicist and cosmologist born in 1942 in Oxford, England. He suffered from amyotrophic lateral sclerosis, becoming almost completely paralyzed, yet made groundbreaking contributions to the fields of cosmology and quantum gravity. Some of his most notable works include collaborating with Roger Penrose on gravitational singularity theorems and predicting that black holes emit radiation. He was also a bestselling author and subject of films that helped raise his public profile as a scientist.
Edward Jenner was born in 1749 in England and is known as the father of immunology. He discovered the cure for smallpox through observing that milkmaids who had previously contracted cowpox did not get smallpox. Jenner hypothesized that cowpox could be used to cure smallpox. Through experimenting by using cowpox as a vaccination for smallpox, he found his hypothesis to be true. His discovery of vaccination led to vaccines becoming common and saving millions of lives worldwide.
Stephen Hawking was a renowned theoretical physicist and cosmologist born in England in 1942. He studied physics and cosmology at Oxford and Cambridge universities. Hawking was diagnosed with ALS at age 21 but defied the odds to survive for over 50 years with the disease, which left him paralyzed. Despite his disability, he was able to continue his groundbreaking research on black holes and the origins of the universe. Some of his major contributions include developing the theory of Hawking radiation and showing how black holes can emit particles. He also helped develop links between gravity and quantum mechanics. Hawking authored several popular science books and was awarded numerous honors for his scientific achievements, including the Presidential Medal of Freedom.
Robert Koch was a German physician and scientist who is considered one of the founders of bacteriology. He developed experimental techniques to isolate bacteria and prove they cause specific diseases, such as showing that Bacillus anthracis causes anthrax. Koch established four steps, known as Koch's postulates, to identify the microorganisms that cause diseases. His work helped prove the germ theory of disease and led to advances in combating disease through isolation of pathogens like anthrax, tuberculosis, and cholera.
This document provides an overview of bioterrorism. It begins with definitions of bioterrorism and a brief history of biological weapons use. It then describes various biological agents that could potentially be used for bioterrorism, classified by the CDC into Categories A, B, and C based on their ease of transmission and potential to cause harm. The document discusses India's existing preparedness measures against bioterrorism and the roles of dentists. It emphasizes the importance of prevention, early detection, and treatment in combating bioterrorism. Laboratories play a key role in the detection and identification of biological agents.
Barack Obama was born in 1961 in Hawaii to a Kenyan father and American mother. He graduated from Columbia University and Harvard Law School, then worked as a civil rights attorney and law professor. Obama was elected to the Illinois State Senate in 1996 and U.S. Senate in 2004, becoming the first African American president in 2008. As president, Obama signed economic stimulus bills and health care reform legislation while dealing with wars in Iraq and Afghanistan.
Stephen Hawking was born in 1942 in Oxford, England. He studied physics and cosmology at Oxford and Cambridge. He was diagnosed with ALS at age 21 but survived far longer than doctors predicted. Hawking made groundbreaking contributions to theoretical physics and cosmology, including proving that black holes emit radiation and theorizing about the origins and eventual end of the universe. He authored the popular science book "A Brief History of Time" and received numerous honors. Hawking continued his research despite being paralyzed and communicating through computers until his death in 2018.
Stephen Hawking was a renowned physicist and author who overcame amyotrophic lateral sclerosis (ALS) to make groundbreaking contributions to the fields of cosmology and physics. He had a normal childhood but was later diagnosed with ALS, a neurodegenerative disease. Despite his illness, he completed his PhD at Cambridge and had a successful career, making predictions about black holes and the origin of the universe. Hawking worked diligently throughout his life to advance scientific knowledge.
Introduction to bioterrorism , history of bioterrorism, key features of biological agents used as bioweapons, biological agents and effects, bioterrorism agents, effects of biological attacks, COVID-19 used as bioweapon , technology at work, preventive measures.
Jonas Salk was an American physician born in 1914 who developed the first successful polio vaccine in 1947 while director of virus research at the University of Pittsburgh. He discovered the vaccine for polio which dramatically transformed public health by preventing future cases of the disease with no detected side effects, earning him awards like the Lasker award.
The document discusses the history and development of the polio vaccine. It describes how the polio vaccine was created to prevent polio, a viral disease that causes paralysis. There are two main types of polio vaccines - the inactivated polio vaccine (IPV) developed by Jonas Salk, and the oral polio vaccine (OPV) developed by Albert Sabin. The IPV uses dead virus and is administered via injection, while the OPV uses live attenuated virus and is taken orally. Widespread use of polio vaccines has nearly eradicated the disease globally.
Dear Doctor,
Its humbling that you liked the presentation and would like to use it for your purpose. Kindly find your requested presentation attached with this email.
The shortlink for your future reference is http://go.drankush.com/PolioFinal
We would always appreciate if you would place this reference as a due credit in your work and while sharing for others use.
Ankush, Amroskar S, Bhamaikar V, Barreto J. "Polio Final Presentation" Accessed from http://go.drankush.com/PolioFinal
-----------------------------------------------------
As we near eradication of this dreaded disease - "POLIO", we would like to share the following presentation we made for our Pediatrics seminar in 2012.
Best attempts have been made to cover most of the topic, keeping the size under 100 slides.
Hope you like it.
Ankush
Shahin Amroskar
Varsha Bhamaikar
Joyce Barreto
Louis Pasteur was born in 1822 in France. He had a successful career as a chemist and professor, making several important scientific discoveries around microbiology. Some of his key discoveries included proving that fermentation is caused by microorganisms, discovering that microorganisms can be both aerobic and anaerobic, and developing the process of pasteurization. Late in his career, he developed the first vaccines against rabies and cholera, saving many lives and establishing the field of vaccination. He died in 1895 and was buried at the Pasteur Institute in Paris.
Vaccines and their effect on public healthGriffin Walker
The document discusses the history and science of vaccines. It begins with a brief history of vaccines from ancient concepts of inoculation to Jonas Salk's creation of the polio vaccine in the 1950s. It then explains how most vaccines work by using weakened or dead microbes to stimulate the immune system to create memory cells that provide long-term protection. The document also notes that vaccines have led to the eradication of deadly diseases and establish herd immunity. However, it acknowledges there is an anti-vaccine debate centered around disproven claims about links between vaccines and autism or harmful ingredients like thimerosal.
Andrew Wakefield published a study in 1998 claiming a link between the MMR vaccine and autism. This led to reduced vaccination rates. An investigation found Wakefield committed ethical violations and intentionally falsified data. In 2010, he was found guilty of professional misconduct and the Lancet retracted his study. While initially influential, extensive subsequent research has found no link between vaccines and autism.
The document discusses the history of antibiotics and antibiotic resistance. It describes some of the key events in the discovery of antibiotics like penicillin and sulfonamides. It also discusses the emergence of resistant bacteria like MRSA and how bacteria can develop resistance through mechanisms such as modifying antibiotic targets, inactivating enzymes, or pumping antibiotics out of the cell. The evolution of antibiotic resistance is an ongoing process driven by selective pressure from antibiotic use.
Louis Pasteur was a French scientist born in 1822 who made groundbreaking discoveries in microbiology and vaccinations. He discovered that microorganisms caused wine and beer to spoil by viewing them under a microscope. He also discovered that heating liquids killed the microorganisms, a process now known as pasteurization. Additionally, Pasteur developed vaccines for anthrax, cholera and rabies by intentionally weakening pathogens, protecting animals and humans from these deadly diseases. He established research centers called Pasteur Institutes around the world before passing away in 1895, leaving a profound legacy in medical science.
Alexander Fleming was a British scientist who in 1928 discovered penicillin, the first antibiotic substance produced by a microorganism. While working with staphylococci bacteria, he noticed the antibacterial properties of the Penicillium mold that inhibited their growth. He published his findings in 1929 and his discovery of penicillin led to the development of other antibiotics and revolutionized medicine by allowing previously deadly diseases to be treated. In 1945, Fleming was awarded the Nobel Prize in Medicine for his discovery of penicillin.
A introduction on Viral vaccine for medical students.Although most attenuated vaccines are viral, some are bacterial in nature. Examples include the viral diseases yellow fever, measles, rubella, and mumps, and the bacterial disease typhoid.
Polio is a viral disease spread through person-to-person contact or fecal contamination. It primarily affects children and causes paralysis in a small percentage of cases by infecting the central nervous system. While most infections cause mild flu-like symptoms, it can also damage respiratory muscles and require use of an iron lung. Developing countries with poor sanitation are most at risk. An effective vaccine was developed in the 1950s, reducing cases dramatically.
Louis Pasteur was born in 1822 in Dôle, France to a family that valued patriotism and hard work. He showed a talent for science from a young age and went on to study at the prestigious École Normale Supérieure in Paris. There, he made groundbreaking discoveries in crystallization and molecular asymmetry that laid the foundations for the new field of stereochemistry. Later in his career, Pasteur developed vaccines against deadly diseases like anthrax and rabies by growing them in sterile conditions. He also invented the process of pasteurization to prevent spoilage in foods like milk and wine by heating them, vastly improving public health. Pasteur founded the Pasteur Institute in Paris, where
This was a group presentation at our faculty of pharmacy ain shams university supervised by department of pharmaceutics we were a team of ten members but i was the one concerned with organizing data , collecting photos , choosing a powerpoint template ,adjusting it to fit in with the topic.
This document discusses different types of vaccines and factors that can lead to vaccine failure. It describes several types of vaccines including live attenuated, inactivated/killed, toxoid, subunit, recombinant subunit, recombinant vector, DNA, and transitional vaccines. It compares advantages and disadvantages of different vaccine types. The document also lists numerous potential causes of vaccine failure, such as use of expired vaccines, improper storage, genetic resistance, health status of individuals receiving the vaccine, immunosuppression, mycotoxins, stress, genetics, administration errors, water quality, and presence of maternal antibodies or variants in the field.
This document provides an overview of vaccines, including their history, types, and uses. It discusses how Edward Jenner developed the smallpox vaccine in 1796 and how Louis Pasteur later developed vaccines for chicken cholera and anthrax in the 1880s. The document outlines seven main types of vaccines: live attenuated, inactivated, subunit, toxoid, conjugate, DNA, and recombinant vector vaccines. It also discusses saponins' potential as vaccine adjuvants and research efforts to develop vaccines, such as for HIV.
The document provides an overview of the history and development of vaccines. It discusses key events like Jenner's development of the smallpox vaccine in 1796 and the eradication of smallpox. It describes different types of vaccines including live-attenuated, inactivated, toxoid, subunit, conjugate, and DNA vaccines. The mechanisms of how vaccines work and produce immunity are also explained. The document traces the evolution of vaccines from whole organism approaches to modern techniques like recombinant DNA technology.
This document provides information about immunization and vaccination. It discusses how immunization works to protect the body from infectious diseases through vaccination or exposure to antigens. The document also includes Nigeria's national immunization schedule, which recommends vaccines for diseases like polio, diphtheria, pertussis, and measles at various ages from birth through adolescence. It notes that minor side effects like fever or rashes are normal after some vaccinations. Only high fever or other severe reactions require medical attention.
This document discusses antimicrobial agents and antibiotics. It defines antimicrobial agents as chemicals that treat infectious diseases by inhibiting or killing pathogens. Ideal antimicrobial agents kill or inhibit pathogens, are not harmful to the host, cause no allergic reactions, and remain effective after storage and in tissues. The document then discusses different classes of antibiotics based on their source, mechanism of action, and targets, including cell wall synthesis inhibitors like penicillin and vancomycin, protein synthesis inhibitors like tetracyclines and chloramphenicol, and nucleic acid synthesis inhibitors like sulfonamides. It also addresses resistance acquisition through intrinsic, mutational or acquired genetic means.
Jonas Salk discovered and developed the first successful inactivated polio vaccine. He conducted research while attending medical school that formed the basis for his later work on the polio vaccine. Albert Sabin developed an oral polio vaccine using weakened live viruses that could be administered orally. His vaccine was found to be more effective than the earlier Salk vaccine at preventing the initial intestinal infection of polio and further transmission of the virus. Rudolf Virchow made seminal contributions including establishing the cell theory and cellular pathology. He discovered that diseased cells arise from already diseased cells and focused on clinical observation and pathological anatomy.
Jonas Salk was an American medical researcher who developed the first successful polio vaccine. He was born in 1914 to Russian-Jewish immigrant parents and showed early academic promise. After initially considering a career in law, Salk decided to study medicine and enrolled in medical school. His research on the flu virus led him to focus his efforts on polio. Working tirelessly in his lab, Salk developed the first effective polio vaccine in 1955. Though hailed as a medical hero, Salk shunned publicity and declined to patent the vaccine in order to make it accessible to all. He later established the Salk Institute to further biological research and worked internationally to distribute vaccines globally. Salk received many honors for his work, including
Unethical human experimentation in the United States - WikiNot Relevant
Unethical human experimentation in the United States included deliberately infecting people with diseases, exposing people to biological and chemical weapons, performing surgical experiments without anesthesia, and injecting people with toxic substances. Many of these experiments were performed on children, prisoners, or the mentally ill without their consent. The experiments were often funded by the U.S. government and military and kept secret for many years, leading to public outcry and congressional investigations when revealed.
The document summarizes the unethical Tuskegee Syphilis Study conducted from 1932 to 1972 by the U.S. Public Health Service to study the natural progression of untreated syphilis in African American men in Alabama. Over 400 men with syphilis were never informed and were denied treatment even after penicillin was found to be an effective treatment. The study was exposed in 1972 and led to major reforms in human subject research ethics and regulations to protect participants, including the 1979 Belmont Report.
1) Henrietta Lacks is a woman whose cancer cells were used to create the first immortal human cell line.
2) George Gey, a researcher at Johns Hopkins, took cells from Henrietta Lacks' tumor and found they could be grown indefinitely in a lab. He named the cell line "HeLa" after her initials.
3) HeLa cells were the first human cells successfully cloned and have been widely used in medical research, including the development of the polio vaccine.
Review of the history of Vaccination and Inoculation, and the diseases that have been reduced due to the immunization program. An epidemiological transition approach is taken to evaluating the decline in the current preventive care system that exists for infections diseases. Asks the question--"Will Polio ever return?"
Polio, Measles, Influenza, and More – 1962 Had More Problems than a COVID Epi...Donald Dale Milne
We had a lot more virus diseases to worry about in 1962 than COVID! Most viral diseases did not have vaccines yet, and some ravaged the whole world. Read more...
The United States has a long history of encouraging science and innovation dating back to the Enlightenment period. Many of America's founding fathers like Benjamin Franklin and Thomas Jefferson were scientists who made important contributions. The US Constitution also aimed to promote scientific progress. Throughout history, American scientists and inventors have made groundbreaking discoveries and inventions across many fields like electricity, aviation, medicine, and space exploration that have benefited society.
Polio is a potentially fatal viral disease that mainly affects young children and used to be more common in the United States and other countries. While vaccines have reduced cases significantly worldwide, it is still found occasionally in Afghanistan and Pakistan. The poliovirus enters the body through the mouth and multiplies in the throat before invading the nervous system, where it can cause muscle paralysis. Widespread vaccination beginning in the 1950s has now nearly eradicated polio globally.
This document provides a history of epidemiology, covering its origins and key figures. It traces epidemiology back to ancient Greece and discusses its modern definition as the study of disease distribution and determinants in populations. Some important developments include John Graunt establishing demographic analysis in the 1600s, James Lind identifying citrus as preventing scurvy in 1747, Edward Jenner developing vaccination against smallpox in 1796, Ignaz Semmelweis reducing childbed fever mortality via handwashing in 1847, and John Snow linking cholera to contaminated water in 1854. These pioneers helped establish epidemiology's objectives of identifying disease causes and evaluating preventive measures.
The Tuskegee Syphilis Study was a clinical study conducted between 1932 and 1972 by the U.S. Public Health Service to observe the natural progression of untreated syphilis in rural African American men in Alabama. Over 600 men infected with syphilis were enrolled in the study under the guise of receiving free health care from the U.S. government, but they were never informed they had syphilis and were intentionally denied effective treatment even after penicillin became the standard treatment in 1947. The study was exposed and ended in 1972 due to public outcry over the grossly unethical treatment of human subjects.
contributions of scientists in historyNitin Teotia
Stephen Hawking was a renowned cosmologist known for his contributions to theoretical physics and his bestselling books on cosmology. He developed motor neuron disease in his early 20s but continued his scientific work despite being wheelchair-bound. Some of his major scientific works included developing the theory of black hole evaporation and penning the popular science book A Brief History of Time. Alexander Fleming discovered the antibiotic penicillin in 1928 after accidentally observing antibacterial properties in a fungus growing in one of his culture dishes. This discovery revolutionized medicine and earned him a Nobel Prize. Both men made seminal scientific contributions despite facing significant health challenges.
Tuskegee Tests
Provides information as to the REASONS why the FEDERAL BUREAU OF INVESTIGATION, JUDICIAL COMPLAINTS and CONGRESSIONAL COMPLAINTS Filed by Vogel Denise Newsome are being OBSTRUCTED from being PROSECUTED!
Garretson Resolution Group appears to be FRONTING Firm for United States President Barack Obama and Legal Counsel/Advisor (Baker Donelson Bearman Caldwell & Berkowitz) which has submitted a SLAPP Complaint to OneWebHosting.com in efforts of PREVENTING the PUBLIC/WORLD from knowing of its and President Barack Obama's ROLE in CONSPIRACIES leveled against Vogel Denise Newsome in EXPOSING the TRUTH behind the 911 DOMESTIC TERRORIST ATTACKS, COLLAPSE OF THE WORLD ECONOMY, EMPLOYMENT violations and other crimes of United States Government Officials. Information that United States President Barack Obama, The Garretson Resolution Group, Baker Donelson Bearman Caldwell & Berkowitz, and United States Congress, etc. do NOT want the PUBLIC/WORLD to see. Information of PUBLIC Interest!
Variola virus, otherwise known as smallpox, is believed to have first emerged in Africa around 10,000 BC and subsequently spread to other parts of the world. It was a serious infectious disease that impacted populations for centuries prior to its eradication. Key events in combating smallpox included variolation experiments in the 1700s, Edward Jenner's pioneering smallpox vaccination using cowpox in 1796, and the World Health Organization's global Smallpox Eradication Programme of the 1960s and 1970s that ultimately succeeded in eliminating the virus by 1980.
1. The document lists notable Filipino and foreign scientists.
2. The Filipino scientists contributed to areas like nutrition, agriculture, medicine, and technology. Their work helped address issues in the Philippines.
3. The foreign scientists included Anders Celsius, Thomas Edison, Nicolaus Copernicus, and Benjamin Franklin, known for their contributions to astronomy, physics, and invention.
Sir William Osler was a Canadian physician known as the "Father of Modern Medicine". He made seminal contributions to medical education by insisting students learn from direct observation of patients at bedside. He established the first residency program and reduced reliance on lectures, prioritizing hands-on clinical training. Osler also authored influential medical textbooks and essays, and helped found Johns Hopkins Hospital and School of Medicine, revolutionizing medical research and teaching standards in North America. His emphasis on thorough physical exams, compassionate care, and equanimity continue to guide physicians over a century later.
Science Round up: James Watson BiographyAsharabIrfan
This is a Biography of James Watson's life.
This presentation contains the facts about James Watson's life, from where did he get his education, his awards, his family, the books he wrote and etc.
Polio is an infectious disease that attacks the nervous system and can cause paralysis. It was once an epidemic in the US, especially affecting children. In 1953, Jonas Salk invented the first polio vaccine, which was tested on monkeys before being administered to humans. By 1960, Albert Sabin had created an oral polio vaccine that became widely used. The vaccines were successful in drastically reducing polio cases in the US, with only 61 cases reported in 1965 compared to 58,000 in 1952.
Today marks the death of the Austrian zoologist Konrad Lorenz in 1903. He was the founder of modern ethnology (the study of animal behaviour by means of comparative zoological methods). He was known affectionately by his pupils as the "father of the grey geese" which he studied. His ideas revealed how behavioural patterns may be traced to an evolutionary past, and he was also known for his work on the roots of aggression. He shared the 1973 Nobel Prize for Physiology and Medicine, for developing a unified, evolutionary theory of animal and human behaviour.
Immortal Women Essays In Medical Eponyms IiCelso Silva
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Information and Communication Technology in EducationMJDuyan
(𝐓𝐋𝐄 𝟏𝟎𝟎) (𝐋𝐞𝐬𝐬𝐨𝐧 2)-𝐏𝐫𝐞𝐥𝐢𝐦𝐬
𝐄𝐱𝐩𝐥𝐚𝐢𝐧 𝐭𝐡𝐞 𝐈𝐂𝐓 𝐢𝐧 𝐞𝐝𝐮𝐜𝐚𝐭𝐢𝐨𝐧:
Students will be able to explain the role and impact of Information and Communication Technology (ICT) in education. They will understand how ICT tools, such as computers, the internet, and educational software, enhance learning and teaching processes. By exploring various ICT applications, students will recognize how these technologies facilitate access to information, improve communication, support collaboration, and enable personalized learning experiences.
𝐃𝐢𝐬𝐜𝐮𝐬𝐬 𝐭𝐡𝐞 𝐫𝐞𝐥𝐢𝐚𝐛𝐥𝐞 𝐬𝐨𝐮𝐫𝐜𝐞𝐬 𝐨𝐧 𝐭𝐡𝐞 𝐢𝐧𝐭𝐞𝐫𝐧𝐞𝐭:
-Students will be able to discuss what constitutes reliable sources on the internet. They will learn to identify key characteristics of trustworthy information, such as credibility, accuracy, and authority. By examining different types of online sources, students will develop skills to evaluate the reliability of websites and content, ensuring they can distinguish between reputable information and misinformation.
How to Manage Reception Report in Odoo 17Celine George
A business may deal with both sales and purchases occasionally. They buy things from vendors and then sell them to their customers. Such dealings can be confusing at times. Because multiple clients may inquire about the same product at the same time, after purchasing those products, customers must be assigned to them. Odoo has a tool called Reception Report that can be used to complete this assignment. By enabling this, a reception report comes automatically after confirming a receipt, from which we can assign products to orders.
How to Setup Default Value for a Field in Odoo 17Celine George
In Odoo, we can set a default value for a field during the creation of a record for a model. We have many methods in odoo for setting a default value to the field.
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إضغ بين إيديكم من أقوى الملازم التي صممتها
ملزمة تشريح الجهاز الهيكلي (نظري 3)
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تتميز هذهِ الملزمة بعِدة مُميزات :
1- مُترجمة ترجمة تُناسب جميع المستويات
2- تحتوي على 78 رسم توضيحي لكل كلمة موجودة بالملزمة (لكل كلمة !!!!)
#فهم_ماكو_درخ
3- دقة الكتابة والصور عالية جداً جداً جداً
4- هُنالك بعض المعلومات تم توضيحها بشكل تفصيلي جداً (تُعتبر لدى الطالب أو الطالبة بإنها معلومات مُبهمة ومع ذلك تم توضيح هذهِ المعلومات المُبهمة بشكل تفصيلي جداً
5- الملزمة تشرح نفسها ب نفسها بس تكلك تعال اقراني
6- تحتوي الملزمة في اول سلايد على خارطة تتضمن جميع تفرُعات معلومات الجهاز الهيكلي المذكورة في هذهِ الملزمة
واخيراً هذهِ الملزمة حلالٌ عليكم وإتمنى منكم إن تدعولي بالخير والصحة والعافية فقط
كل التوفيق زملائي وزميلاتي ، زميلكم محمد الذهبي 💊💊
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THE SACRIFICE HOW PRO-PALESTINE PROTESTS STUDENTS ARE SACRIFICING TO CHANGE T...indexPub
The recent surge in pro-Palestine student activism has prompted significant responses from universities, ranging from negotiations and divestment commitments to increased transparency about investments in companies supporting the war on Gaza. This activism has led to the cessation of student encampments but also highlighted the substantial sacrifices made by students, including academic disruptions and personal risks. The primary drivers of these protests are poor university administration, lack of transparency, and inadequate communication between officials and students. This study examines the profound emotional, psychological, and professional impacts on students engaged in pro-Palestine protests, focusing on Generation Z's (Gen-Z) activism dynamics. This paper explores the significant sacrifices made by these students and even the professors supporting the pro-Palestine movement, with a focus on recent global movements. Through an in-depth analysis of printed and electronic media, the study examines the impacts of these sacrifices on the academic and personal lives of those involved. The paper highlights examples from various universities, demonstrating student activism's long-term and short-term effects, including disciplinary actions, social backlash, and career implications. The researchers also explore the broader implications of student sacrifices. The findings reveal that these sacrifices are driven by a profound commitment to justice and human rights, and are influenced by the increasing availability of information, peer interactions, and personal convictions. The study also discusses the broader implications of this activism, comparing it to historical precedents and assessing its potential to influence policy and public opinion. The emotional and psychological toll on student activists is significant, but their sense of purpose and community support mitigates some of these challenges. However, the researchers call for acknowledging the broader Impact of these sacrifices on the future global movement of FreePalestine.
Temple of Asclepius in Thrace. Excavation resultsKrassimira Luka
The temple and the sanctuary around were dedicated to Asklepios Zmidrenus. This name has been known since 1875 when an inscription dedicated to him was discovered in Rome. The inscription is dated in 227 AD and was left by soldiers originating from the city of Philippopolis (modern Plovdiv).
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2. He was an American
medical researcher
and a virologist who
is known as a
developer of the first
successful vaccine
against poliomyelitis.
3. Full Name Jonas Edward Salk
Birthdate October 28, 1914
Birthplace East Harlem, New York
Father’s Name Daniel B Salk
Occupation Garment worker
Mother’s Name Dora Press
Religion Orthodox Jewish - Polish
Name of Spouse Donna Lindsay
Occupation Social Worker
Children Peter Salk
Darrel Salk
Jonathan Salk
4. HIGH SCHOOL
Townsend Harris High School
COLLEGE
City College of New York
MEDICAL SCHOOL
Dr Salk with his mentor Dr Thomas Francis
New York University
School of Medicine
"As a child I was not interested in science. I was
INTERNSHIP merely interested in things human, the human side of
nature, if you like, and I continue to be interested in
Mt Sinai Hospital that.”
-Jonas Salk, MD
courtesy of his interview in Academy of Achievement
5. “. . .it was the laboratory work, in particular, which gave new direction to his
life.”
- Oshinsky
He moved to the University of Michigan to join Dr. Francis and
worked on an army-commissioned project in Michigan to
develop an influenza vaccine in which it is a formalin-killed-
virus vaccine
He accepted an offer from William McEllroy, dean of the
University of Pittsburg Medical School, to be an associate
research professor of bacteriology where he continued his
research on flu vaccines
6. "Paralytic poliomyelitis (its formal name) was, if not the
most serious, easily the most frightening public health
problem of the postwar era.”
- William O’Neill, American Historian
A girl infected by the virus
Jonas Salk talks to children with polio
“…scientists were in a In 1952 58,000 cases of polio
frantic race to find a
Parents carry a stricken child was reported with 3, 145
cure.” during the polio scare.
- O’neill people dying
7. Polio Myelitis causes
permanent paralysis in
those it strikes or chronic
Polio patients in an Iron Lungs in 1952 shortness or breath often
leads to death
He used a killed- virus vaccine, in By 1951, Salk was able to
which it was killed with formaldehyde classify the polio viruses
in 13 days. into 3 types
The first people to be inoculated with
Salk’s vaccine were his wife and 3
children.
8. Salk and the National Foundation for Infantile Paralysis
conducted the first field trial of Salk’s vaccine in 1952 involving
20,000 physicians and public health officers, 64,000 school
personnel and 220,000 volunteers with over 1, 800, 000
children in trial
9. In April 12, 1955, Dr Francis who monitor the
results, declared that. . .
10. The success brought Salk to instant stardom:
He received offers from Hollywood; Pleas from top
manufacturers to endorse their products; He was awarded
with a congressional medal for great ahievement and was
nominated for a Nobel Prize.
In 1957, he became a professor in Experimental Medicine in
University of Pittsburg.
He began to work on vaccines against viral infections in the
central nervous system.
Salk also conducted important research on the prevention and
treatment of influenza, multiple sclerosis, cancer, and
Acquired Immune Deficiency Syndrome.
11. In the same year as Salk
developed the killed-virus
vaccine. He developed the
live-virus vaccine against
polio which is taken orally
rather than intravenously
in the same year as Salk
developed the killed-virus
vaccine.
US did not permitted him
to make a field trial in the
country, and Sabin did it
in Europe which was
effective too.
Dr Albert Sabin
12. Although Jonas Salk is credited
with ending the scourge of polio
because his killed-virus vaccine
was first to market, Albert
Sabin’s sweet-tasting and
inexpensive oral vaccine are
commonly used worldwide.
"The live virus vaccine is highly
effective in developed countries ...”
-Dr Salk in his press conference in 1980
13. By 1963, Salk opened an institute called Salk
Institute for Biological Studies under his
leadership.
"I thought how nice it would be if a
place like this existed and I was
invited to work there.“
- Dr Salk in 1963
14. 1956, awarded the Lasker Award
1957, the Municipal Hospital building is renamed Jonas
Salk Hall and is home to the University's School of
Pharmacy and Dentistry
1958, awarded the James D. Bruce Memorial Award
1975, awarded the Jawaharlal Nehru Award and the
Congressional Gold Medal
1976, Jonas Salk received the Academy of Achievement's
Golden Plate Award
1976, named the Humanist of the Year by the American
Humanist Association
15. 1977, awarded the Presidential Medal of Freedom from
President Jimmy Carter
2006, the United States Postal Service issued a 63 cent
Distinguished Americans series postage stamp in his honor.
2007, California Governor Arnold Schwarzenegger and First
Lady Maria Shriver inducted Salk into the California Hall of
Fame
2009, BBYO boys chapter chartered in his honor in
Scottsdale, Arizona, named "Jonas Salk AZA #2357"
Schools in Mesa, Arizona; Spokane, Washington; Tulsa,
Oklahoma; Bolingbrook, Illinois; Levittown, New York; Old
Bridge, New Jersey; Merrillville, Indiana, and Sacramento,
California, are named after him.
16. In 1966, New York times
referred to him as the
Father of Biophilosophy.
"As a biologist, he believes that his
science is on the frontier of tremendous
new discoveries; and as a philosopher,
he is convinced that humanists and
artists have joined the scientists to
achieve an understanding of man in all
his physical, mental and spiritual
complexity.”
- Howard Taubman, New York times Journalist
17. Jonas Salk died from heart failure at the age of
80 on June 23, 1995 in La Jolla and was buried
at El Camino Memorial Park in San Diego.
18. http://www.squidoo.com/jonas-salk
http://en.wikipedia.org/wiki/Jonas_Salk
http://pabook.libraries.psu.edu/palitmap/bios/Salk__Jona
s.html
http://www.libraries.uc.edu/liblog/wp-
content/uploads/2012/04/sabinandnixon.jpg
http://img.tfd.com/mk/S/X2604-S-04.tif.png
http://www.polioplace.org/people/jonas-salk-md
David M. Oshinsky, Polio: An American Story, Oxford
University Press, 2005. Jeffrey Kluger, Splendid Solution:
Jonas Salk and the Conquest of Polio, Berkley Trade, 2006
Jonas Salk interview with Academy of Achievement
Taubman, Howard. "Father of Biophilosophy" The New
York Times, Nov. 11, 1966
19. “There are two types of medical specialists. There are those who
fight disease day and night, who assist mankind in times of
despair and agony and who preside over the awesome events of
life and death. Others work in the quiet detachment of the
laboratory; their names are often unknown to the general
public, but their research may have momentous consequences”
Dr Jonas Edward Salk
in Wisdom Magazine 1956
Editor's Notes
On 7 June 1939, Salk was awarded his M.D. The next day, he married Donna Lindsay, a Phi Beta Kappa psychology major who was employed as a social worker. The marriage would produce three sons: Peter, Darrell, and Jonathan. After graduation, Salk continued working with Francis, and concurrently began a two-year internship at Mount Sinai Hospital in New York. Upon completing his internship, Salk accepted a National Research Council fellowship and moved to the University of Michigan to join Dr. Francis, who had been heading up Michigan'sdepartment of epidemiology since the previous year. Working on behalf of theU.S. Army, the team strove to develop a flu vaccine. Their goal was a "killed-virus" vaccine--able to kill the live flu viruses in the body, while simultaneously producing antibodies that could fight off future invaders of the same type, thus producing immunity. By 1943, Salk and Francis had developed a formalin-killed-virus vaccine, effective against both type A and B influenza viruses, and were in a position to begin clinical trials.In 1946, Salk was appointed assistant professor of epidemiology at Michigan.Around this time he extended his research to cover not only viruses and the body's reaction to them but also their epidemic effects in populations. The following year he accepted an invitation to move to the University of Pittsburgh School of Medicine's Virus Research Laboratory as an associate research professor of bacteriology. When Salk arrived at the Pittsburgh laboratory, whathe encountered was not encouraging. The laboratory had no experience with thekind of basic research he was accustomed to, and it took considerable efforton his part to bring the lab up to par. However, Salk was not shy about seeking financial support for the laboratory from outside benefactors, and soon his laboratory represented the cutting edge of viral research.
58,000 cases of polio were reported in 1952, with 3,145 people dying and 21,269 left with mild to disabling paralysis
Polio myelitis, traceable back to ancient Egypt, causes permanent paralysis in those it strikes, or chronic shortness of breath often leading to death. Children, in particular, are especially vulnerable to the polio virus. The University of Pittsburgh was one of four universities engaged in trying to sort and classify the more than one hundred known varieties of polio virus. By 1951, Salk was able to assert with certainty that all polio viruses fell into oneof three types, each having various strains; some of these were highly infectious, others barely so. Once he had established this, Salk was in a positionto start work on developing a vaccine.
20,000 physicians and public health officers, 64,000 school personnel, and 220,000 volunteers,"[18] with over 1,800,000 school children participating in the trial.
The success of the trial catapulted Salk to instant stardom. He was inundatedwith offers from Hollywood and with pleas from top manufacturers for him toendorse their products. He received a citation from President Eisenhower andaddressed the nation from the White House Rose Garden. He was awarded a congressional medal for great achievement in the field of medicine and was nominated for a Nobel Prize but, contrary to popular expectation, did not receive it. He was also turned down for membership in the National Academy of Sciences,most likely a reflection of the discomfort the scientific community still felt about the level of publicity he attracted and of continued disagreement with peers over his methods.
polio virus lived and multiplied in the small intestine. An oral vaccine, he believed, might block the virus from entering the bloodstream, destroying it before it spread.
It was called the Salk Institute for Biological Studies and opened in 1963 in the San Diego neighborhood of La Jolla. Salk believed that the institution would help new and upcoming scientists along their careers as he said himself, "I thought how nice it would be if a place like this existed and I was invited to work there." This was something that Salk was deprived of early in his life, but due to his achievements, was able to provide for future scientists.