This document discusses infiltration and extravasation which are complications of intravenous (IV) therapy. Infiltration occurs when IV fluid leaks into surrounding tissue due to improper catheter placement or dislodgement. Extravasation is when vesicant (toxic) drugs leak into tissue. Both can cause swelling, pain, and tissue damage. To prevent these complications, health care providers should select appropriate IV sites, use proper insertion technique, securely fix catheters, and monitor sites frequently. If complications occur, the IV should be removed and the site elevated, documented, and further treated based on symptoms and severity.