This document discusses the International Health Regulations (IHR), which provide a framework for international cooperation to control the spread of diseases. Some key points: 1. The IHR aim to prevent the international spread of diseases, encourage surveillance and capacity building, and ensure prompt notification of public health emergencies. 2. Vaccination requirements are outlined for certain diseases like smallpox, plague, cholera, and yellow fever. Smallpox vaccination is no longer recommended. 3. National IHR Focal Points have been established in countries to act as communication channels with WHO. India's focal point is the National Institute of Communicable Diseases. 4. The document outlines core surveillance and response capacities