BLAST AND LEAF SPOT OF FINGER MILLET or RAGI or MANDUWA or NAACHNI, प्राचीन काल से ही हमारे देश में पारम्परिक मोटे अनाज जैसे कि ज्वार, जौं, मक्का आदि का सेवन किया जाता रहा है। इन्हीं मोटे अनाजों में से एक है रागी। यह अनाज सेहत के लिए बहुत ही लाभकारी है
Wilt is a pernicious disease of guava in India.
In India the disease was first recorded near Allahabad in 1935 . The infection was reported 15 -30 %.
The disease is a serious threat to guava cultivation in U.P. In West Bengal it reduces the yield in affected orchard by 80% .
The disease is also prevalent in Haryana Rajasthan , A.P ,
Punjab and M.P.The exact cause of the disease is still not fully understood but the pathogens viz. Fusarium oxysporum f. sp. psidii (Prasad, Mehta & Lal), Rhizoctonia spp. (Taub.) and various pathogens are reported by different workers may be the incitant of the disease.
Survival and spread:
Through movement of plants containing sick soil in virgin areas.
Short distance spread is by water.
Root injury predisposes wilt disease.
It has forced uprooting of about 150 acre of guava orchard in Panjab and 300 acres in Haryana during 1971-81.
Disease and Insect Pest of Ber and their ManagementRamkumarrai3
Ber (Zizyphus Spp.) is a most important fruit and more nutritive value for the purpose of dryland fruit production. Its require heavy pruning during April- May .
Pear is the temperate fruit grown mainly in temperate regions or in regions of higher altitudes.
Here, Pest infesting pear fruits and its management stratergies are dealt here
BLAST AND LEAF SPOT OF FINGER MILLET or RAGI or MANDUWA or NAACHNI, प्राचीन काल से ही हमारे देश में पारम्परिक मोटे अनाज जैसे कि ज्वार, जौं, मक्का आदि का सेवन किया जाता रहा है। इन्हीं मोटे अनाजों में से एक है रागी। यह अनाज सेहत के लिए बहुत ही लाभकारी है
Wilt is a pernicious disease of guava in India.
In India the disease was first recorded near Allahabad in 1935 . The infection was reported 15 -30 %.
The disease is a serious threat to guava cultivation in U.P. In West Bengal it reduces the yield in affected orchard by 80% .
The disease is also prevalent in Haryana Rajasthan , A.P ,
Punjab and M.P.The exact cause of the disease is still not fully understood but the pathogens viz. Fusarium oxysporum f. sp. psidii (Prasad, Mehta & Lal), Rhizoctonia spp. (Taub.) and various pathogens are reported by different workers may be the incitant of the disease.
Survival and spread:
Through movement of plants containing sick soil in virgin areas.
Short distance spread is by water.
Root injury predisposes wilt disease.
It has forced uprooting of about 150 acre of guava orchard in Panjab and 300 acres in Haryana during 1971-81.
Disease and Insect Pest of Ber and their ManagementRamkumarrai3
Ber (Zizyphus Spp.) is a most important fruit and more nutritive value for the purpose of dryland fruit production. Its require heavy pruning during April- May .
Pear is the temperate fruit grown mainly in temperate regions or in regions of higher altitudes.
Here, Pest infesting pear fruits and its management stratergies are dealt here
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
2. 1. BORER
• Rhinoceros beetle - Oryctes rhinoceros Linn. (Family-
Scarabaeidae Order-Coleoptera)
NATURE OF DAMAGE
The adult beetles bores into the stem causing wilting of plants.
MANAGEMENT
Remove and destroy damaged plants.
Collect and destroy various bio-stages from manure pits.
Mix entomogenous fungal culture of Metarhizium anisopliae in the manure
pits during cooler months to attack grubs.
Encourage Reduviid bugs, Platymeris laevicollis to attack adults.
Hook out and kill adults from the base of stems.
Set up light traps following first rains in summer and monsoon period to
attract adults.
Soak castor cake at 1 kg in 5 1 of water in small mud pots and keep them in
the pineapple garden to attract the adults.
Use Rhinolure vane trap for attracting adults.
3. MARK OF IDENTIFICATION
Egg: Oval creamy white egg in manure pits or decaying
vegetable matter at a depth of 5 to 15 cm. Egg periods is
8 to 18 days. Female laid 140 to 150 eggs.
Grub: Grub is stout, sluggish, white “C”-shaped with
pale brown head and found at a depth of 5 to 30 cm.
Pupa: Grub pupates in earthen cells at a depth of 0.3 to
1m.
Adult: Adult beetle is stout, brownish black or black
and has a long horn projecting dorsally from the head
in male. Horn is short in female.
Fig- Rhinoceros beetle
Fig- Rhinoceros Grub
4. 2. SAP FEEDERS
1. Thrips - Thrips tabaci Lind. (Family-Thripidae
Order- Thysanoptera)
NATURE OF DAMAGE
The nymphs and adults which shelter between the leaf sheaths and stems
lacerate the epidermis and suck the exuding sap.
The affected leaves exhibit silvery which blotches leading to distortion,
wilting and drying from tip down wards.
The seedlings show retarded growth.
The bulbs remain undersized and appear distorted in shape
MARK OF IDENTIFICATION
It reproduces parthenogenetically.
The adult female inserts the eggs into the tender leaves.
The egg period is 10-15 days.
The nymphs and adults are yellow in colour.
The nymphal period is 4-6 days.
It pupates in soil. The pupal period is 3 days.
The pest undergoes 10 generation per year.
5. MANAGEMENT
Use neem coated urea which reduce the infestation of pest.
Set up sky-blue colour sticky traps which attract more adults than
yellow colour traps.
Spray methyl demeton or dimethoate at 1 ml/litre or monocrotophos 1
ml/litre with teepol 0.5 ml/litre of water.
Grow resistant varieties viz., White Persian, Grano, Sweet Spanish,
and Crystal wax.
6. 2. Mealybug -Dysmicoccus brevipes Cockerell.
(Family- Pseudococcidae Order-Hemiptera)
NATURE OF DAMAGE
Both nymphs and adults desap the leaves and fruits result yellowing of
leaves and shriveling of fruits.
MAK OF IDENTIFICATION
Live in colonies underground with only a small proportion living on the leaves.
Occurrence of mealy bug wilt is largely correlated with the subterranean colony
on the roots.
Arial individuals are to be found mostly at the base of the leaves
Fig- Mealy bug
7.
8. MANAGEMENT
Cultivate resistant varieties like Red Spanish and
Queen.
Collect planning material from unaffected
plantations.
Remove basal brownish leaves of cured planting
materials at the time of planting.
Dip basal portion of planting material in methyl
parathion 0.2% solution as a prophylactic measure.
Apply phorate 10 G at 17.5 kg/ha at 100-125 days
interval in the affected plantations.
9. 3. Slug caterpillar - Parasa lepida (Family-
Cochlididae Order - Lepidoptera)
NATURE OF DAMAGE
Larva feeds on leaves voraceously leaving only the midrib and veins results
in severe defoliation
MARK OF IDENTIFICATION
• Egg: Flat shiny eggs on the under surface of leaves
• Larva: Greenish body with white lines and four rows of spiny scoli tipped
red or black, which cause irritation and pain.
• Pupa: It pupates in a compact elliptical chocolate brown shell like cocoon,
which is convex above and flat ventrally as stems. Cocoons are covered with
irritating spines and hairs
• Adult: Adult moth has green wings with prominent dark patch at the base of
each forewing.
10. MANAGEMENT
Eggs are laid in groups and covered with hairs on the leaves.
Egg period is 4-5 days. Larva is stout, slug like ventrally flat,
greenish body with white lines and four rows of spiny scoli
tipped red or black. Larval period is 40-45 days.
It pupates in plant as cocoons covered with irritating spines
and hairs.
Adult moth is green with brown band at the base of each fore
wings.