The document discusses induction of parturition, or inducing labor, in animals. Induction of parturition may be recommended for reasons like unwanted pregnancy, fetal issues, or preventing difficulties during birth due to disproportion between the fetus and pelvis. The process is controlled by hormones in a feedback loop between the fetus, placenta, and mother. As gestation ends, cortisol from the fetal adrenal gland prepares the lungs, liver, and thyroid for birth. This affects the placenta to shift hormone production from progesterone to estrogen and prostaglandin F, which signals the corpus luteum to decrease progesterone. Once progesterone levels drop, contractions intensify, aided by oxytocin, to expel the fetus from

1. INDUCTION OF PARTURITION

2. • Its also known as inducing labor — is prompting the
uterus to contract during pregnancy before labor
begins on its own for a vaginal birth.
• Inducing labor recommend for various reasons,
PARTURITION
• The expelling of the fully formed young one
from the mother's uterus after the completion
gestation period
• the process of your baby leaving the uterus
(womb)
 Induction Of Parturition

3.  Misidentification of a breeding female
 Accidental breeding of a very young heifer, and
 Unwanted pregnancy
 To prevent dystocia due to feto-pelvic disproportion
 INDICATIONS
During Normal Gestation
• Abortion
• Fetal maceration
• Fetal mummification
• Hydramnios, and hydrallantois.
During Abnormal Gestation
The most common problem associated with the induction of parturition in cows is retention of the fetal membranes.

4. Fetus controls time of parturition due to stress response
 Lack of space
 - Lack of gas exchange
 - Lack of nutrients
SHOWS SINGS OF PARTURATION
 Fetal control of parturition

5. Fetal pituitary -- hypothalamus axis essential
• increased stress from fetal nutritional demands
and placental insufficiency
• Hypothalamus release CRH
(Corticotropin releasing hormone)
• Anterior pituitary in turn releases ACTH
 Hormonal Changes At The End Of Gestation

6. Fetal Adrenal Gland
in response to ACTH releases
cortisol Which effects fetus
• Lung produces surfactants
• liver increases storage of glycogen
• thyroid increases metabolism
Effects Of Cortisol On Placentome
• shift from progesterone
to estradiol production
• progesterone decreases
• estrogen increases
• PGF increases
 Hormonal Changes At The End Of Gestation

7. o Increase in uterine oxytocin receptors
o primes cervix to response to relaxin
o stimulates ovary to secrete relaxin and
oxytocin acts with PGF to trigger CL regression
 Hormonal Changes At The End Of Gestation
Placentome hormones
Estradiol- increase gap junctions in myometrium
• leads to better co-ordination and communication
among muscle cells in the myometrium
• begin to get coordinated contractions toward the
cervix-

8.  Hormonal Changes At The End Of Gestation
PGF
• PGF- regression of CL-
• Synthesis and release of oxytocin and relaxin from
ovary (in some species relaxin from placenta)
• Stimulates most of the contractions in the uterus

9. • P4 shift from progesterone to estrogen
production leads to its decrease from
the placentome
• PGF stimulates luteolysis so
progesterone from CL decreases
• release from "progesterone block"
 PROGESTERONE

10. • stimulates final contractions of uterus but
only once fetal head enters cervix
 OXYTOCIN

11.  INDUCTION OF PARTURITION

12. PGF2α

13.  GLUCUCURTICOIDS

14.  Termination Of Pregnancy

15. INDUCTION OF PARTURITION COW

16. INDUCTION OF PARTURITION EWE

17.  Manual Techniques

18.  Hydramnios, And Hydrallantois

19.  Fetal Mummification

20. REFERENCE
https://www.s.net/MahalingeshwaraMali/induction-of-parturition-amp-elective-
termination-of-pregnancy
R.A Mcfeely and V. K. Ganjam -Induction of parturition in farm animal 1976, 7 (2, 151-156.

21. Thank you