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Immunization Essentials
1. IMMUNIZATION
Submitted to
Respected paraveen William
Faculty College of Nursing
vmmc & sjh
Submitted by
Mehroon nissa
Enrollment No : 75250306619
Bsc (H) Nursing 4th year
2. DEFINATION OF IMMUNIZATION
It is the process of rendering the subject immune by
inoculating with a specific antigen which induces an
immune response.
3. Types of Immunity
Active immunity;
It is produced by administering vaccine or toxoid.
Long lasting.
Passive immunity;
It is produced by administering immunoglobulins
This produces immediate protection which only lasts for
some weeks or month
4. Herd Immunity
Herd immunity exists if the number of people in a
community who have active immunity against an infection
exceeds a critical level .
If this level is achieved then even non-vaccinated
individuals are protected from getting the disease .
5. Vaccine
The vaccine is usually a protein similar to part of a
virulent infectious organism that can be recognized by the
individual’s immune system, which then produces
antibodies or cell-mediated immunity against the antigen
in the vaccine .
6. Type of Vaccines
Live attenuated vaccine
A virulent organism is weakened so that it produces an
antigenic response without the serious consequences of a
wild organism infection .
Killed or inactivated vaccines
Prepared from preformed antigen inactivated by heat, phenol
, formaldehyde or some other means.
Conjugated Vaccines
Conjugated with other antigens in an attempt to improve the
immunological response.
Toxoids
These are toxins , which have been rendered non-toxic by
treatment with formaldehyde, but their antigenicity is
maintained.
7. Antibacterial Vaccines
Live attenuated bacteria:
BCG, oral typhoid
Killed bacteria:
Pertussis , Cholera and injectable typhoid.
Toxoids:
Diphtheria, Tetanus.
Polysaccharide vaccines :
Meningococcal, Pneumococcal, H. Influenzae type b.
14. Contraindications
Live vaccines are contraindicated in
Immune deficient children
Children on steroids and chemotherapy
Children with Organ transplant
House hold members of above children
Within 6 weeks of receiving immunoglobulins
Pertussis is contraindicated in
Epilepsy
Encephalopathy
All
Anaphylactic reaction to previous vaccines.
High grade fever above 102F
15. Adverse Effects
Fever
Swelling, redness or pain at vaccination site
Deep abscess (BCG)
Lymphadenopathy (BCG)
Generalized TB in immunocompromised children(BCG, rare)
Vaccine induced Paralytic polio in immunocompromised
children(BCG1:6million)
Inconsolable cry (pertussis)