GENETIC APPROACH TO SKIN AGING YOUR iDDNA® IS A PERSONALIZED ANTI-AGING PROGRAM BASED ON YOUR REAL BIOLOGICAL AGE (NOT YOUR CHRONOLOGICAL AGE), THAT STIMULATES YOUR BODY’S NATURAL ANTI-AGING POWERS, DELIVERING AGE MANAGEMENT AT A CELLULAR AND MOLECULAR LEVEL. The right ingredients, the right formulations, the right order. THE SECRET OF ANTI-AGING IS IN YOUR GENES Up to 60% of the skin aging variation between individuals can be attributed to genetic factors, while the remaining 40% is due to non-genetic factors. PERSONALIZE YOUR ANTI-AGING REGIMEN. www.idna.works

1. MADE TO MEASURE
FROM YOUR PATIENT’S DNA
iDDNA®
Anti-aging programs
personalized on DNA
designed and developed in Switzerland

2. WHEN A FLOWER
DOESN’T BLOOM
YOU FIX
THE ENVIRONMENT
IN WHICH IT GROWS,
NOT THE FLOWER.
-Alexander Den Heijer-

3. AGING IS LIKE AN ICEBERG
OBJECTIVE DIAGNOSIS
WHAT YOU CAN SEE
WITH A GENETIC APPROACH
THE ROOT CAUSE
Is your patient at
risk of over reactive
inflammation?
SKIN SENSITIVITY
TNFα
Is your patient protected
against free radicals damage?
FREE RADICALS DAMAGE
SOD
GPX
GSTM
GSTT
Is your patient
predisposed to
premature wrinkling?
WRINKLING
COL3a1
ELN
Emilin
MMP3
Is your patient at risk of
reduced hyaluronic acid
synthesis?
MOISTURIZATION
FLG
HAS1
TNFα
Is your patient predisposed
to collagen breakdown?
COLLAGEN BREAKDOWN
PPARG
TNFα
How susceptible is your
patient to sun damage?
PHOTO-AGING
ASIP
KITLG p53
CDK10
Does your patient have an
optimal cell renewal rate?
SKIN REGENERATION
NOS3
TNFα

4. PERSONALIZATION OF SKIN
AGING REGIMENS
Several theories have been tested regarding the pathomechanisms
of aged skin, however fundamental mechanisms still remain
misunderstood.
Research shows there is an influence of genetics on skin aging,
specifically the differences observed in the ethnic populations
between genders.
Recent studies indicate that male and female aged skin differs in the
type, consistency and sensitivity to external factors. The same has
also been documented between elderly people of different origins.
Consequently, the aging process taking place in both genders
and in diverse ethnic groups should be examined separately. The
products customized to each population should also be developed
independently in order to satisfy special needs.
THE INDIVIDUAL GENETIC SIGNATURE
Skin aging is a complex process influenced by genetic and
environmental factors. Recent studies on twins have revealed that
up to 60% of the skin aging variation between individuals can be
attributed to genetic factors, while the remaining 40% is due to
non-genetic factors. Recent advances in genomics and bioinformatics
approaches have led to the association of certain single nucleotide
polymorphisms (SNPs) to skin properties.
Researchers have identified the key proteins and SNPs associated
with certain properties of the skin that contribute to skin aging.
They selected a set of 13 SNPs in gene coding for these proteins
which are potentially associated with skin aging associated with
skin aging and concluded:
• Individuals can be divided into genetic clusters defined by genotypic
variables.
• These genotypic variables are linked with polymorphisms in one
or more genes associated with certain properties of the skin that
contribute to a person’s perceived age.
• Using this classification, it is possible to characterize human
skincare and anti-aging needs on the basis of an individual’s genetic
signature, thus opening the door to personalized treatments that
are addressed at specific populations.
SCIENTIFIC REFERENCES
Makrantonaki E, Bekou V, Zouboulis CC.
Genetics and skin aging.
Dermatoendocrinol. 2012 Jul 1; 4(3):280-4.
SCIENTIFIC REFERENCES
Naval J, Alonso V, Herranz MA.
Genetic polymorphisms and skin aging: the identification of population genotypic groups holds potential for personalized treatments.
Clin Cosmet Investig Dermatol. 2014; 7:207-14.

5. 23%
21%
15%
9%
7%
7%
6%
6%
INFLAMMATORY
RESPONSE
SKIN
STRUCTURE
CELLULAR
TURNOVER
FREE RADICALS
DAMAGE
BARRIER REPAIR
UV-DAMAGE
PROTECTION
HYDRATION
PIGMENTATION
GENETIC APPROACH TO SKIN AGING
REINVENT ANTI-AGING!
FUNCTIONAL HUMAN GENETIC RESEARCH AT THE MOLECULAR LEVEL ESTABLISHES THE FOUNDATION FOR
THIS NEXT GENERATION DNA-BASED SKIN AGING REGIMEN.
GENES EXPRESSION INFLUENCED BY TOPICAL
APPLICATION OF PRODUCTS
EPIDERMIS
YOUNG SKIN OLD SKIN
Keratinocites Collagen ElastinFibroblast
DERMIS

6. m a d e - f o r - Y O U
1 in 113.246.210 iDDNA®
programs
iDDNA®
ultra-custom
ANTI-AGING PERSONALIZED REGIMEN
8 BOOSTERS included
Other treatments are suggested
as options on an individual
patient basis, but not included
in the protocol.
113.246.210
INDIVIDUAL TREATMENT
COMBINATIONS
Science of [DNA] f(x)™ =[(1+1)x(82
x323
x63
)]+2 =
1 ACTIVE DAYTIME FOUNDATION TREATMENT
1 ACTIVE NIGHTIME FOUNDATION TREATMENT
+ 8 PRECISION professional strength solutions
+ (1+1) PRIMARY ACTIVATION
+ 2 LONG-TERM INTENSIVE CARE
+ 32 BOOSTERS
+ 6 ANTI-AGING NUTRICOSMETICS

7. BEFORE AFTER
BEFOREAFTERBEFORE AFTER
DOES IT REALLY WORK?
iDDNA®
technology has been created after 8+ years of research & development.
More than 6,000 patients have been treated with previous release of the platform, on
Nobel prize-winning research and internationally accepted scientific and medical
publications.
Real people. Real results.
47 yrs old, man70 yrs old, woman
51 yrs old, woman After 3 weeks. Daily use.
After 5 weeks. Daily use.

8. HOW DO YOU GET STARTED?
CONTACT US TO BECOME AN AUTHORIZED PROVIDER OF iDDNA®
.
Call +41 091 29 01 888 or email info@suisselifescience.com.
WANT TO LEARN MORE
SCHEDULE A WEBINAR.
UNDERSTANDING THE BIOLOGY OF AGING
TRACKING YOUR PATIENT’S INDIVIDUAL GENETIC CODE
DESIGNING YOUR PATIENT’S PERSONAL ANTI-AGING
www.suisselifescience.com
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iDDNA®, [iD]DNA®, Science of [DNA]f(x)™,CLINICare® and all its brands, trademarks, products and materials belong exclusively to Suisse Life Science S.A. and are to be used for informational purposes only. All our distributors,
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are not intended, and should not be used, to diagnose or treat any diseases or medical conditions.