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DNA-personalised
WHAT WORKS FOR ONE PERSON, 
DOES NOT NECESSARILY WORK 
FOR ANOTHER PERSON. 
GENETICS CREATES A NEW CLASS OF SKINCARE TECHNOLOGY. 
We know that not every skincare product is going to suit everyone, 
no matter how much the cosmetic industry tells you. 
And this is why there are so many brands out there and literally 
thousands of different products. 
LIFE IS COMPLICATED, BUT BEAUTY DOESN’T HAVE TO BE. 
idna.works 
PERSONALISED 
REALLY PERSONALISED 
3
Science of [DNA] f(x)™ = GENES VS LIFESTYLE 
No more guesswork, no more buying products that feel like they might help. 
THERE IS NO ONE-SIZE FITS ALL FOR OUR CUSTOMERS. 
We replaced skincare guesswork with genetically-designed cosmeceuticals OTC (over the counter) 
and nutricosmetics supplements. 
THE RIGHT INGREDIENTS, IN THE RIGHT FORMULATIONS, IN THE RIGHT ORDER. 
Science of [DNA] f(x)™ proprietory statistical algorithms grows in accuracy day by day with [iD]DNA® growing 
sample set. 2014 population for Science of [DNA] f(x)™ is about more than 20.000 DNA population wide 
samples stored entirely in-house, making [iD]DNA® ultra-custom biologically active treatment leading 
the way in wellness personal genetics predictions. 
GENETICS 
VS 
LIFESTYLE 
[iD]DNA® ultra-custom IS SMART SCIENCE 
INDIVIDUAL TREATMENT PLANS 
THAT PERFORM AS THEY CLAIM 
A SIMPLE, ADVANCED, 
PERSONALISED TREATMENT PLAN 
SUITED FOR TODAY BUSY LIVES 
HOW MUCH OF YOUR SKIN AGING 
CAN YOU ACTUALLY CONTROL? 
While genetics do play a large role in how quickly you will age, recent research has started 
to show that the habits you develop and choices you make throughout life might be even more 
telling, so with your genetically customised ANTI-AGING plan you have control over 
how your skin ages. 
A PERSONALISED 
TREATMENT PLAN 
4 [iD]DNA 5 ® 
ultra-custom
WE FOCUS ON GENES VS LIFESTYLE: 
How much of your skin aging can you control? 
IF YOU WANT TO STAY YOUNG WITH AGE, 
YOU NEED TO KNOW YOUR GENE-EXPRESSION AGE. 
LET’S DISCOVER YOUR SKIN IDENTITY! 
FIGHT YOUR 
EXPIRATION DATE 
6 [iD]DNA 7 ® 
ultra-custom
THE 
DNA CODE 
IS THE KEY 
SCIENTIFIC 
APPROACH 
Aging is a gradual, irreversible process that occurs 
as a number of changes in the appearance 
and texture of the different skin structures. 
Your DNA is the code containing all the information 
necessary to our cells to develop over time 
[iD]DNA® IS THE FIRST DNA-PERSONALISED 
ANTI-AGING TREATMENT IN THE WORLD 
8 [iD]DNA 9 ® 
ultra-custom
STAY YOUNG WITH AGE! 
DO YOU REALLY KNOW IF YOU’RE YOUNGER 
OR OLDER THAN YOUR BIRTH-CERTIFICATE AGE? 
LET’S FOCUS ON 
GENES VS LIFESTYLE: 
How much of your aging 
can you really control? 
DNAge 
The first DNA-personalised prescription 
strength treatment to help you fight 
your SKIN AGING concerns on your 
GENE-EXPRESSION AGE. 
DNADiet 
The DNA-personalised weight loss 
management plan to help you manage 
successfully your weight on your 
GENE-EXPRESSION EATING PROFILE. 
DNACell 
The first DNA-personalised CELLULITE 
treatment to help you fight the severity 
stage of your GENE-EXPRESSION 
CELLULITE GRADE. 
DNAHair 
The DNA-personalised HAIR LOSS 
treatment to help you fight your 
GENE-EXPRESSION HAIR LOSS STAGE. 
DNASport 
The first DNA-personalised SPORT 
PERFORMANCE optimisation plan to 
help you choose the sport that best 
suits you and improve your performances 
to your maximum potential. 
TURN BACK 
THE CLOCK 
10 [iD]DNA 11 ® 
ultra-custom
1 
As you’ve done your simple DNA assessment, you’re ready to discover research-grade lifelong 
scientific remarks and suggestions. 
2 
3 
This [iD] GUIDE comes with your [iD] GENETIC REPORT. 
Ask your consultant to fully understand any insight and connect to idna.works to create your 
[iD]DNA® 15 days-trial of your [iD]DNA® ultra-custom foundation treatment. 
Your very individual treatment: the right ingredients, intensity, dose, dosage and the right order 
depends on your [iD]DNA® score, a benchmark of individual GENES vs LIFESTYLE expression age. 
4 
IT’S TIME FOR YOUR TREATMENT 
TO GET PERSONAL 
ONE-SIZE DOES FIT YOU 
ULTRA-CUSTOM 
YOUR DNA TEST 
Do you want real results? 
[iD]DNA® ultra-custom, the first and only genetically-guided 
skincare treatment in the world. 
Specific deficits. 
Individual benefits. 
Precision skincare treatments. 
[iD]DNA® ASSESSMENT 
[iD]DNA® GENETIC REPORT 
[iD]DNA® ULTRA-CUSTOM BIOLOGICALLY ACTIVE TREATMENT 
Each [iD]DNA® treatment is engineered on scientific studies (in vivo) clinical efficacy 
terms of application and parameterised to individual GENES vs LIFESTYLE guidance. 
[iD]DNA® CHALLENGE 
Your follow up for evidence-based performance. 
[iD]DNA® technology measures your results and how much you could improve more... 
DNA-PERSONALISATION 
You’re unique and your beauty is unique, only a personalised 
treatment will work for you. 
[iD]DNA® ultra-custom is the luxury of a customised 
science-based skincare treatment made specifically for you. 
Because your genes don’t lie. 
GET RESULTS 
Forget trials and errors. Get results now! 
Your [iD]DNA® ultra-custom treatment plan will provide you: 
• THE RIGHT INGREDIENTS 
• THE RIGHT FORMULATIONS 
• THE RIGHT ORDER 
Prescription strength. With no need of prescription. 
THE TRUTH 
[iD]DNA® is the only concept to accept the challenge 
of proving on you the effectiveness of your personalised 
treatment. Change perspective, focus on GENES vs LIFESTYLE 
to calculate your gene-expression age (younger or older 
than your birth-certificate age?) 
REAL SCIENCE. REAL RESULTS. 
[iD]DNA® 
YOUR IDENTITY 
[iD]DNA® 
THE CONCEPT 
TREATMENT-PACK 
60 days 2 months 
120 days 4 months 
120 days 6 months 
240 days 8 months 
CONCERNS 
Anti-Aging 
Anti-Aging • Cellulite Treatment • Weight Loss Management • Body Contouring 
Cellulite Treatment • Weight Loss Management • Hair Loss Treatment 
Hair Loss Treatment 
12 [iD]DNA 13 ® 
ultra-custom
YOUR [iD] GENETIC REPORT 
HOW TO READ YOUR [iD] 
2 6 
YOUR [iD] GENETIC PROFILE 
Gene Cromosome Genotype 
FLG Filaggrin 1q21.3 II 
MMP3 Stromelysin-1 also called matrix metalloproteinase 3 11q22.2 5A/5A 
ELN Elastin 7q11.23 -/A 
PPARG Cellular receptor PPARG 3p25.2 CC 
SOD Superoxide dismutase 2 6q25.3 TC 
GSTT Glutathione S-transferase T-1 22q11.23 INS 
GSTM Glutathione S-transferase M-1 1p13.3 DEL 
NOS3 Endothelial nitric oxide synthase 7q36.1 5/5 
TNFα Endothelial nitric oxide synthase α 6p21.33 GG 
EMILIN1 Emilin 1 2p23.3 CG 
COL3a1 Collagen 2q32.2 GG 
GPX Glutathione peroxidase 3p21.31 CT 
HAS1 Hyaluronic acid synthetase 19q13.41 GG 
GENETIC EVALUATION DECODING KEY 
OPTIMAL genetic function 
ALTERED genetic function 
ADVERSE genetic function 
GENE-EXPRESSION AGE 
Your [iD] DNA index* 
Determined upon the basis of genetic testing combined with your lifestyle self-optimisation 
[1] Wrinkling (firmness + elasticity) ………………………………………………………………………………………m……e…d……iu…m…… …r…is…k 
[2] Moisturisation (hyaluronic acid potential) ……………………………………………………………in…c……re……a…s…e…d… …r…is…k 
[3] Skin Hydration (hydro-lipid film) ……………………………………………………………………………………in…c…r…e…a……s…e…d… risk 
[4] Free radicals damage …………………………………………………………………………………………………………… medium risk 
[5] Regeneration (vascolarisation + oxygenation) …………………………………………………r…e…d…u…c……e d risk 
[6] Sensivity + Inflammation ………………………………………………………………………………………………………r…e…d…u…c……e…d… …r…is…k… … 
VISIBLE EFFECTS BIOLOGICAL EFFECTS 
soft skin[1] 
balanced tone and elasticity maintenance[1] 
potential premature skin aging[2] 
possible loss of subcutaneous fat on the face resulting in the 
appearance of wrinkles and skin folds[2] 
soft and shiny skin[3] 
proper hydration[3] 
possible sagging skin in the form of unsightly wrinkles or expression 
lines[6] 
possible predisposition to hypersensitive and reactive skin[6] 
54% 
unaltered hydro-lipid film barrier protection[4] 
good protection against free radicals damage and oxidative stress[5] 
effective elimination of toxic substances[5] 
correct cell regeneration[1] 
protection against external agents[1] 
maintenance of firmness[1] 
possible alteration in the production of pro-inflammatory 
cytokines[2] 
risk of developing flogistic phenomena[2] 
fair hydrating ability[3] 
normal ability to retain water[3] 
insufficient intake of nitric oxide[6] 
possible minor defense and regeneration capabilities against 
exogenous stimuli[6] 
possible minor firmness of the dermis[6] 
[ ] brackets indicates the number of the area in which the effect of which it refers. 
100 OPTIMAL + + Base level FOLLOW UP -- recommended 
0 MAXIMUM RISK - - MAXIMUM SUPPORT recommended + + 
*[iD] DNA® index is the benchmark of the Swiss patent pending concept [iD] DNA® ultra-custom, 
showing your scoring in terms of GENES vs. LIFESTYLE. [iD] DNA® index is created on 
your genetics, balanced by the interference of individual habits by anamnestic self-assessment. 
Your area [iD] DNA® index will be processed by the Science of [DNA] f(x)™ to get your 
recommended treatment plan. 
The scale [iD] DNA® index ranges from 100 to 0. 
GENETICAL GUIDANCE FOR YOUR TREATMENT PLAN 
The genetic variant analyzed predispose to a reduced state of hydration. Your skin is less able to 
retain water, appearing less tonic. Your genetics also expose skin to the risk of developing intense 
dryness phenomena and loss of relaxing capacity. 
To counter the adverse effects to which your genetics predispose you it is important to follow few 
recommendations that may be useful to improve your state of hydration, delaying the onset of 
aging phenomena and helping skin remain firmer for longer. 
Given that intense exposure to UV rays coming from the sun may cause skin damage, it is 
recommendable to use sunscreens and avoid the hours of maximum intensity. UV rays are also 
emitted from sunlamps used in tanning treatments. 
The best international scientific references recommend you a corrective treatment based on these 
suggestions. 
Pentavitin® is a 100%-natural ingredient, made in Switzerland, ECOCERT, to feel deep hydration 
for 72 hours. Clinically tested to effectively stimulate genes that play a key role in skin barrier 
improvement.* 
Moreover, to improve the aspects analyzed in this area, the treatment should also include 
hyaluronic acid, sodium hyaluronate crosspolymer, biosaccharide gum-1. 
Strictly following the treatment plan that you can create with this genetical guidance, the [iD] 
DNA index® for SKIN MOISTURISATION will improve up to 36%. 
VISIBLE EFFECTS BIOLOGICAL EFFECTS 
POSSIBLE SAGGING SKIN IN THE FORM OF UNSIGHTLY WRINKLES 
OR EXPRESSION LINES 
POSSIBLE PREDISPOSITION TO HYPERSENSITIVE AND REACTIVE 
SKIN 
INSUFFICIENT INTAKE OF NITRIC OXIDE 
POSSIBLE MINOR DEFENSE AND REGENERATION CAPABILITIES 
AGAINST EXOGENOUS STIMULI 
POSSIBLE MINOR FIRMNESS OF THE DERMIS 
AREA [2] 
*all clinical data refers to in vitro ed in vivo clinical studies for claim substantiations by the manufacturers, from their product dossier. Data used for internal training on treatment 
functionalities and outcomes presentation. Available evidence documentation on request. 
SNP DETAIL 
Gene 
HAS1 Hyaluronic acid synthetase 
Hyaluronic acid bestows skin the particular properties of plasticity, 
strength, and shape retention thanks to its moisturizing ability. In 
fact, it is able to bind a large number of molecules of water, 
ensuring greater skin hydration. 
The presence of a polymorphism at this gene level, may contribute 
to a lesser state of hydration of skin. 
Your DNA test highlighted the presence of the disadvantageous GG 
variant which renders the HAS1 enzyme less functioning. The 
reduction of hyaluronic acid which follows causes skin to appear 
less hydrated, as it retains less water molecules. 
Cromosome Genotype 
18 GG 
Locus Telomere localisation 
18q13.41 13.41 
AREA [2] 
DNA-RECOMMENDED ACTIVE INGREDIENTS 
CLINICAL PRESCRIPTION 
TOPICAL INGREDIENTS NUTRITIONAL INGREDIENTS 
ACETIL HEXAPEPTIDE-50 
CAPRYLIC/CAPRIC TRIGLYCERIDE (AND) TEPRENONE 
CERAMIDE 3 (AND) CERAMIDE 6 II (AND) CERAMIDE 1 (AND) 
PHYTOSPHINGOSINE 
CHRYSANTHUS BULB EXTRACT 
COPPER TRIPEPTIDE-1 
DIMETHILMETHOXY CHROMANOL 
GLYCOPROTEINS, GLUTAMIC ACID, VALINE, THREONINE 
SOY ISOFLAVONES 
ISOTHIOCYANATES 
L-ASCORBIC ACID 15% 
OZONIZED OLEIC ACID 
PHYTOCELLTEC MALUS DOMESTICA 
PROANTHOCYANIDIN PHOSPOLIPID COMPLEX 
TRIPEPTIDE-10 CITRULLINE 
HYALURONIC ACID 
SODIUM HYALURONATE CROSSPOLYMER 
BIOSACCHARIDE GUM-1 
SACCARINE ISOMERATE 
DMAE-DIMETHYLAMINOETHANOL 
HYDROLIZED RICE PROTEIN, GLYCINE SOJA PROTEIN, 
SUPEROXIDE DISMUTASE 
OLIGOPEPTIDE-68 
PALMYTOL TRIPEPTIDE-5 
SUPEROXIDE DISMUTASE 
ACETYL TETRAPEPTIDE PLATINIUM 
NIACINAMIDE 
POLLEN EXTRACT (AND) GLYCINE SOJA 
GLYCINE SOYA PROTEIN (AND) SUPEROXIDE DISMUTASE (AND) 
SODIUM DEXTRAN SULFATE 
OLIGOPEPTIDE-34 
ACETYL DECAPEPTIDE-3 
ALPHA-LIPOIC ACID 
ELLAGIC ACID 
NIACIN (VITAMIN B3) 
SUPEROXIDE DISMUTASIS 560 UI 
VITAMIN C 
VITAMIN D 
BIOTIN (VITAMIN H) 
RECOMMENDED BIOACTIVE INGREDIENTS 
ACETIL HEXAPEPTIDE-50 
Juveleven® is the guardian of your genomic integrity, by protecting and repairing DNA damage 
and delays senescence: cell rejuvenation by over 10 years*. Key element in preserving the vital 
code. Reverts senescence in fibroblasts. 
ACETYL DECAPEPTIDE-3 
CG-Rejuline® is a bio-mimetic complex, which prevents the formation of expression lines and 
wrinkles, promoting active cell regeneration. It's a new technology that revitalise and regenerate 
your skin. CG-Rejuline® strengthens elasticity and improves skin quality, inducing the synthesis of 
collagen type I and elastin. 
ACETYL GLUTAMYL HEPTAPEPTIDE-1 
SNAP-8® is a bio-mimetic epta-peptide safe hi-tech alternative solution to Botox®. Bye, bye 
Botox®: S NAP-8® r educes w rinkles u p t o - 6 3%, a fter 28 days application*, without needles. 
Maximum efficacy for frown lines, crow's feet, expression wrinkles. 
ACETYL HEXAPEPTIDE-8 
Argireline® is a bio-mimetic hexapeptide, specific for the correction of eye contour concerns. It 
relieves congestion in the eye area; it is active against the formation of edema (swelling) caused 
by compromised hemodynamics, against faulty lymphatic circulation, or against high capillary 
permeability. This peptide regulates the loss of skin elasticity and the risk of formation of bags 
under the eyes. It also reduces dark circles. Clinical tests show that it reduces bags under the eyes 
in only 14 days*. 
ACETYL TETRAPEPTIDE PLATINIUM 
Platinum peptide is a bioconjugated high-tech nanoparticle clinically tested for +280% collagen III 
synthesis increase, +250% collagen I synthesis increase, -61% wrinkles reduction, +47% skin 
elasticity, +33% skin hydration, after just 30 days application*. 
ACETYL TETRAPEPTIDE-2 
Uplevity® hi-tech peptide counteract the force of gravity, by increasing collagen and functional 
elastin synthesis, and cellular support. It provides a better structure to the dermis improving the 
quality of mature skin. Clinically tested for +47,3% collagen I synthesis, +21,7% elastin synthesis. 
Uplevity® peptide further contributes to skin firmness by overexpressing genes involved in cellular 
cohesion, that are the interface between the actin cytoskeleton and extracellular matrix (ECM)*. 
The ultra-personalized treatment plan on your genetic identity 
[1] Wrinkling (firmness + elasticity) …………………………………………………………………………………………m……e…d…i…u…m…… r…i…s k 
[iD] DNA index [iD] DNA index TARGET Your DNA reccommends 
59% 69% 
The genetic test highlighted a reduced susceptibility to chrono-aging. 
This means that your skin properly protects against external agents and will 
tend to remain more supple, firm and soft. 
[2] Moisturisation (hyaluronic acid potential) ……………………………………………………………i…n…c…r…e…a…s…e……d risk 
[iD] DNA index [iD] DNA index TARGET Your DNA reccommends 
24% 36% 
The genetic variant analyzed predispose to a reduced state of hydration. Your 
skin is less able to retain water, appearing less tonic. Your genetics also expose 
skin to the risk of developing intense dryness phenomena and loss of relaxing 
capacity. 
[3] Skin Hydration (hydro-lipid film) ……………………………………………………………………………………i…n…c…r…e…a…s…e…d…… r…i…s k 
[iD] DNA index [iD] DNA index TARGET Your DNA reccommends 
30% 35% 
The genetic variant we detected predisposes to an increased accumulation of 
adipose tissue. 
Therefore you may experience alterations in the lipid film with typical 
manifestations of oily skin and acne. 
SCIENTIFIC REFERENCES 
1. The important role of stratum corneum lipids for the cutaneous barrier function. van Smeden J, Janssens M, Gooris GS, Bouwstra JA. Biochim 
Biophys Acta. 2013 Nov 16. doi:pii: S1388-1981(13)00248-5. 10.1016/j.bbalip.2013.11.006. 
2. Connective tissue biochemistry of the aging dermis. Age-associated alterations in collagen and elastin.Uitto J.Clin Geriatr Med. 1989 Feb;5(1):127- 
47. Review. 
3. Effect of the sun on visible clinical signs of aging in Caucasian skin. Flament F, Bazin R, Laquieze S, Rubert V, Simonpietri E, Piot B. Clin Cosmet 
Investig Dermatol. 2013 Sep 27;6:221-32. doi: 10.2147/CCID.S44686. 
4. 5,7-Dimethoxyflavone, an activator of PPARα/γ, inhibits UVB-induced MMP expression in human skin fibroblast cells.Kim JK, Mun S, Kim MS, 
Kim MB, Sa BK, Hwang JK.Exp Dermatol. 2012 Mar;21(3):211-6. doi: 10.1111/j.1600-0625.2011.01435.x. 
5. Peroxisomes in dermatology. Part I.Smith KJ, Dipreta E, Skelton H.J Cutan Med Surg. 2001 May-Jun;5(3):231-43. Epub 2001 May 17. Review. 
6. The role of manganese superoxide dismutase in skin aging. Treiber N, Maity P, Singh K, Ferchiu F, Wlaschek M, Scharffetter-Kochanek 
K.Dermatoendocrinol. 2012 Jul 1;4(3):232-5. doi: 10.4161/derm.21819. 
7. Effects of cigarette smoke extracts on the growth and senescence of skin fibroblasts in vitro. Yang GY, Zhang CL, Liu XC, Qian G, Deng DQ.Int J 
Biol Sci. 2013 Jun 28;9(6):613-23. doi: 10.7150/ijbs.6162. Print 2013. 
8. Endothelial nitric oxide synthase mediates cutaneous vasodilation during local heating and is attenuated in middle-aged human skin. Bruning RS, 
Santhanam L, Stanhewicz AE, Smith CJ, Berkowitz DE, Kenney WL, Holowatz LA. J Appl Physiol (1985). 2012 Jun;112(12):2019-26. doi: 
10.1152/japplphysiol.01354.2011. Epub 2012 Apr 12. 
9. Nitric oxide function in the skin. Cals-Grierson MM, Ormerod AD.Nitric Oxide. 2004 Jun;10(4):179-93. Review. 
10. Aging affects the association between endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction in the Korean male 
population.Park JE, Lee WH, Hwang TH, Chu JA, Kim S, Choi YH, Kim JS, Kim DK, Lee SH, Hong KP, Seo JD, Lee WR.Korean J Intern Med. 
2000 Jan;15(1):65-70. 
11. IL-11, IL-1α, IL-6, and TNF-α are induced by solar radiation in vitro and may be involved in facial subcutaneous fat loss in vivo. Li WH, Pappas A, 
Zhang L, Ruvolo E, Cavender D. J Dermatol Sci. 2013 Jul;71(1):58-66. doi: 10.1016/j.jdermsci.2013.03.009. Epub 2013 Apr 10. 
12. Factors of skin ageing share common mechanisms. Giacomoni PU, Rein G.Biogerontology. 2001;2(4):219-29. Review. 
13. Effect of the sun on visible clinical signs of aging in Caucasian skin. Flament F, Bazin R, Laquieze S, Rubert V, Simonpietri E, Piot B. Clin Cosmet 
Investig Dermatol. 2013 Sep 27;6:221-32. doi: 10.2147/CCID.S44686. 
14. Loss-of-function polymorphisms in the filaggrin gene are associated with an increased susceptibility to chronic 
15. irritant contact dermatitis: a case–control study C.M. de Jongh,*_ L. Khrenova,_ M.M. Verberk,* F. Calkoen,* F.J.H. van Dijk,* H. Voss,_ S.M. 
John_ and S. Kezic**Coronel Institute of Occupational Health, Academic Medical Centre, University of Amsterdam, P.O. Box 22700, Amsterdam 
1100 DE, the Netherlands_National Poisons Information Centre, National Institute for Public Health and the Environment, Bilthoven, the 
Netherlands_Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabru¨ck, Osnabru¨ck, Germany 
16. Matrix metalloproteinase-3 genotype contributes to age-related aortic stiffening through modulation of gene and protein expression.Medley TL, 
Kingwell BA, Gatzka CD, Pillay P, Cole TJ.Circ Res. 2003 Jun 13;92(11):1254-61. Epub 2003 May 15. 
17. Molecular pathology of the elastic fibers. Christiano AM, Uitto J. J Invest Dermatol. 1994 Nov;103(5 Suppl):53S-57S. Review. 
18. Genotype-activity relationship for Mn-superoxide dismutase, glutathione peroxidase 1 and catalase in humans. Bastaki M, Huen K, Manzanillo P, 
Chande N, Chen C, Balmes JR, Tager IB, Holland N Division of Environmental Health Sciences, School of Public Health, University of California- 
Berkeley, Berkeley, CA 94608, USA. 
19. Genotype-activity relationship for Mn-superoxide dismutase, glutathione peroxidase 1 and catalase in humans. 
20. Bastaki M, Huen K, Manzanillo P, Chande N, Chen C, Balmes JR, Tager IB, Holland N. Division of Environmental Health Sciences, School of 
Public Health, University of California-Berkeley, Berkeley, CA 94608, USA. Arch Dermatol Res. 2011 Aug;303(6):445-9. doi: 10.1007/s00403- 
011-1129-9. Epub 2011 Feb 4. 
GUIDANCE FOR YOUR TREATMENT PLAN 
variant analyzed predispose to a reduced state of hydration. Your skin is less able to 
appearing less tonic. Your genetics also expose skin to the risk of developing intense 
phenomena and loss of relaxing capacity. 
adverse effects to which your genetics predispose you it is important to follow few 
recommendations that may be useful to improve your state of hydration, delaying the onset of 
phenomena and helping skin remain firmer for longer. 
intense exposure to UV rays coming from the sun may cause skin damage, it is 
to use sunscreens and avoid the hours of maximum intensity. UV rays are also 
sunlamps used in tanning treatments. 
international scientific references recommend you a corrective treatment based on these 
100%-natural ingredient, made in Switzerland, ECOCERT, to feel deep hydration 
Clinically tested to effectively stimulate genes that play a key role in skin barrier 
improve the aspects analyzed in this area, the treatment should also include 
sodium hyaluronate crosspolymer, biosaccharide gum-1. 
following the treatment plan that you can create with this genetical guidance, the [iD] 
SKIN MOISTURISATION will improve up to 36%. 
EFFECTS BIOLOGICAL EFFECTS 
SKIN IN THE FORM OF UNSIGHTLY WRINKLES 
LINES 
PREDISPOSITION TO HYPERSENSITIVE AND REACTIVE 
INSUFFICIENT INTAKE OF NITRIC OXIDE 
POSSIBLE MINOR DEFENSE AND REGENERATION CAPABILITIES 
AGAINST EXOGENOUS STIMULI 
POSSIBLE MINOR FIRMNESS OF THE DERMIS 
in vitro ed in vivo clinical studies for claim substantiations by the manufacturers, from their product dossier. Data used for internal training on treatment 
outcomes presentation. Available evidence documentation on request. 
[iD]DNA® 
REPORT 
1 5 
3 7 
4 8 
Your [iD] starts with your [iD]DNA® score. 
All the relevant areas in terms of biological 
systems affecting the concerns are detailed 
with visible and biological (internal) effects. 
Rather than simply focus on an analysis 
of your skin health, your [iD]DNA® provides 
active ingredients recommendations, directly 
related to your individual requirements. 
In your [iD] GENETIC REPORT, you find: 
• GENETIC remarks 
• LIFESTYLE recommendations 
• EXERCISE suggestions 
• NUTRITION recommendation 
• ACTIVE INGREDIENTS that suits most your skin. 
[iD]DNA® reveals you the improvement you 
can experience following your [iD]DNA® 
ultra-custom biologically active treatment. 
Follow the suggestions to get results! 
This is your genetic profile. All the SNPs 
involved are presented in detail with your 
genotype and an easy-to-understand 
positive/negative rating. 
Our scientific references library is able 
to define the relationship between 
the active ingredients and the different 
genes variations of your genetic profile. 
The scientific foundation uncovers your 
skin potential. Real science application 
reveals your human genomic profile, for 
more accurately predicting your treatment. 
[iD]DNA® is scientifically backed 
by third parties scientific references, 
you can find and check at the end of your 
[iD] GENETIC REPORT. 
14 [iD]DNA 15 ® 
ultra-custom
PREMIUM SWISS SKIN CARE TECHNOLOGY 
THE SCIENCE OF AGELESS SKIN: 3+5 
REPAIRS, REJUVENATES AND TRANSFORMS SKIN. 
1 1 
2 2 
IN&OUT BENEFITS: + CLINIAge NUTRICOSMETIC 
A DNA-personalised and professional-optimized skin care system designed to work in sinergy 
at the cellular level to help improve and preserve the youthful look and vitality of your skin. 
• PROTECT SKIN STEM CELLS 
• REPAIR DNA 
• SMOOTH OUT WRINKLES FROM THE INSIDE OUT 
• PROTECT THE YOUTHFUL LOOK AND VITALITY OF YOUR SKIN 
Just insert your [iD] code to find out you DNA-personalised treatment: 
FUNCTION 
AGE-DEFYING 
PRECISION 
CORRECTIVE 
INVERTAGE 
AVERAGE DURATIONS 
60 days 2 months treatment 
60/120 days 2-4 months treatment 
120 days 4 months treatment 
240 days 6 months treatment 
IN&OUT 
SUGGESTED 
OPTIONAL 
SUGGESTED 
MANDATORY 
AGE DEFYING 
SKINCARE 
CLEANSE 
FOUNDATION TREATMENT: CLINILift 
+ PRESCRIPTION STRENGTH: booster 
PRECISION TREATMENT: CLINIUV A-B 
CLEANSE 
FOUNDATION TREATMENT: CLINICo2A, 
CLINICo2B 
FOUNDATION TREATMENT: CLINIGf DNA 
+ PRESCRIPTION STRENGTH: booster 
PRECISION TREATMENT: CLINIEye_5 
INTENSIVE CARE: CLINIFace 
(Eye) therapy 
3 3 
4 
5 
every 
2 weeks 
every 
10 weeks 
YOUR [iD]DNA® 
FORGET TRIALS AND ERRORS 
GET RESULTS NOW! 
[iD]DNA® ultra-custom represents an unprecedented approach to skin care. 
Your personalized skin care program started with your [iD]DNA® test. 
• BY TAKING THIS SIMPLE TEST, you unlock the secrets to your skin’s genetic strengths 
and weaknesses. 
• BY TESTING YOUR DNA, now you can scientifically select the professional strength 
treatment that will most benefit your skin’s beauty and health. 
ENJOY YOUR 15 DAYS DNA-PERSONALIZED 
FOUNDATION TREATMENT TODAY! 
AFTER YOUR FIRST 15 DAYS TREATMENT, TO GET 
YOUR FULL DNA-PERSONALISED TREATMENT: 
connect right now to idna.works 
just enter your [iD]code 
select the signs of aging you want to fight in YOU+online adjustement 
It’s easier than you think and it takes only 5 minutes. 
1 
2 
3 
idna.works 
idna.works 
16 [iD]DNA 17 ® 
ultra-custom
CLINICare® 
CLINICEUTICALS 
CLINICare® cliniceuticals is our brand of unique formulations 
for genetically-guided individual treatments, built just for the [iD]DNA® 
ultra-custom concept. 
+ PATENTED SCIENCE 
+ PROPRIETARY FORMULATIONS 
Proprietary formulations 
Scientifically formulated from researchers for targeted efficacy 
ALL THE ACTIVE INGREDIENTS ARE SELECTED TO ENSURE 
AN UNPRECEDENTED COSMETOGENOMICS EFFICACY: 
EXTENDS CELL VITALITY AND LONGEVITY 
Reactivating cells regeneration and renewal in the basal layer of epidermis, 
leading to a higher keratinocyte production. The epidermal tissue becomes 
thicker, denser and more resistant to external aggressions. 
STRENGTHENS THE EXTRACELLULAR MATRIX 
Restoring the dermo-epidermal junction and stimulates fibroblasts achieving 
an increase in the quality and amount of collagen and elastin. 
The skin recovers elasticity and firmness, facial oval has a new sustain 
and expression lines decrease substantially. 
CELL REGENERATION AND REPAIR 
Protecting and reactivating your own dermoepidermal stem cells, with 
selected biomimetic peptides and plant stem cells extracts, strengthening 
the connective tissue structure an improving skin quality and texture. 
INTELLIGENT ANTIOXIDANT ACTION 
Neutralising free radicals contributing to improve the skin’s defence capacity 
and delays the skin aging process. 
HIGH-TECH COSMETIC ENGINEERING 
Encapsulating biomimetic peptides, functional ingredients, plant stem cells 
in release biovectors to transport them and act in the innermost skin. 
They mimics, in their composition and structure, the cell membrane, 
increasing the penetration and diffusion levels. 
18 [iD]DNA 19 ® 
ultra-custom
To make you sure about getting the best results of your [iD]DNA® ultra-custom biologically active 
treatment, we put your smartphone in charge as your personal assistant: 
COMBINATION THERAPY 
DNA 
ASSESSMENT 
ACTIVE TREATMENTS 
cliniceuticals 
FOLLOW UP 
cliniceuticals 
check your [iD]DNA® ultra-custom treatment plan: 
THE RIGHT INGREDIENTS 
THE RIGHT FORMULATIONS 
THE RIGHT ORDER 
[iD]DNA® ultra-custom app will remind you all your treatments with your personalized dose, 
at the right moment. 
COLLECTIONS 
ANTI-WRINKLE 
TIGHTEN & LIFT 
REJUVENATION 
PRECISION 
professional strength 
ACTIVE INGREDIENTS 
TRYLAGEN® functional 
SNAP-8® peptide 
MATRIXYL-3000® peptide 
JUVELEVEN® peptide 
UPLEVITY® peptide 
RELISTASE® peptide 
DMAE 
EGF 
COPPER-peptide 1 
PLATINUM-peptide 
REJULINE® peptide 
PREREGEN® functional 
ARGIRELINE® peptide 
BONT-peptide® 
SYN-AKE® peptide 
SENESTEM® functional 
DERMCOM® functional 
BENEFITS 
• diminishes length and depth 
of lines and wrinkles 
• stimulates collagen regeneration 
for healthy, younger looking skin 
• tightens and firms skin 
• restores elastin to create lift 
and contour 
• intelligent antioxidant action 
• free radicals and sun damage 
protection, DNA repair 
• moisturisation and skin protection 
• renew skin smoothness 
• refine skin texture 
• reveal skin radiance 
• revitalize skin tone 
• intelligent antioxidant action 
• correct eye bags, puffy eyes 
SUSTAINABLE 
SAFE HI-TECH 
COSMECEUTICALS 
PARABEN 
PHTALATE 
SLS 
COMEDOGENIC 
FREE NO 
ANIMAL INGREDIENTS 
ARTIFICIAL COLORS 
AGE-DEFYING 
SKINCARE 
SCIENCE OF [DNA] 
WHAT NEXT? 
YOUR TREATMENT 
AT YOUR FINGERTIPS! 
SEE THE REAL RESULTS! 
[iD]DNA® CHALLENGE 
When you’re about to end your treatment, your [iD]DNA® follow up WILL CHECK YOUR REAL 
IMPROVEMENT to show how your treatment has really worked. 
20 [iD]DNA 21 ® 
ultra-custom
With the passage of time, the skin may experience skin aging, id est 
a series of physiological changes that lead to an increased occurrence 
of micro-wrinkles, loss of elasticity, and skin dryness. 
These changes are mainly due 
to two parallel events: 
CHRONOLOGICAL AGING and 
ENVIRONMENTAL FACTORS. 
CHRONO-AGING depends on genetic factors 
specific to each of us. It begins after the age 
of 25, and it may be visibly manifested from 
40 years onwards. 
We observe at the level of the epidermis a lower 
ability of cells to regenerate with consequent 
thinning of the skin layer. 
Even the skin glands are gradually reducing 
their activity, resulting in reduced production 
of sebum and increased skin dryness. 
Aging is also induced by environmental factors 
such as pollution, stress, unbalanced diets 
or exposure to irritants and harmful substances 
such as cigarette smoke. 
in particular, a very important role is played 
by PHOTO-AGING, which is a chronic and 
premature aging of the skin due to prolonged 
exposure to sunlight and to the formation 
of free radicals. 
Today, aging is worsen by TECHNOLOGICAL-AGING, 
the aging process caused 
by electromagnetic waves of iphones, mobile 
phones, ipads,computers, constantly attacking 
skin moisturisation and hydration barrier. 
WRINKLING 
Firmness + Elasticity 
MOISTURISATION 
Hyaluronic Acid 
Potential 
HYDRATION 
BARRIER 
Hydrolipid Film 
REGENERATION 
Vascolarisation + 
Oxigenation 
SENSITIVITY + 
INFLAMMATION 
BEFORE AFTER 
FREE RADICALS 
DAMAGE 
FLG1 
1q21,3 
MMP311 
11q22,2 
ELN7 
7q11,23 
EMILIN12 
2p23,3 
COL3a1 
2q32,2 
HAS119 
19q13,41 
PPARG3 
3p25,2 
SOD6 
6q25,3 
GSTM1 
1p13,3 
GSTT22 
22q11,23 
GPX3 
3p21.31 
NOS37 
7q36,1 
TNFα6 
6q21,33 
LET’S CALCULATE 
YOUR GENE-EXPRESSION AGE 
Are you younger or older than your birth-certificate age? 
Everyone’s skin is unique, as are their fingerprints and genetic code. 
Your biological and emotional life can be read on your skin. 
Your skin talks your story. 
YOUR DNAge [iD] 
Science of [DNA] f(x)™ = [(1+1) x (8+324+1) x 3)] + 2 = 6.291.512 
22 [iD]DNA ® 
INDIVIDUAL TREATMENT 
23 COMBINATIONS ultra-custom
Nutrigenetics is a new discipline 
that seeks to explain how 
the substances we ingest 
are metabolized and used, 
based on our genes. 
The study of DNA makes it possible 
to determine the exact amount 
of nutrients that each of us requires 
and the reaction you’ve to different 
dietary components. 
DNADiet IS NOT A DIETARY PLAN 
DNADiet PROVIDES SPECIFIC 
NUTRITIONAL RECOMMENDATIONS 
FROM YOUR DNA 
No more dieting, but healthy eating: 
know yourself to take care of yourself 
CAN YOU EAT WHAT YOU 
LIKE, MANAGING SUCCESS-FULLY 
YOUR WEIGHT? 
It is scientifically proven that good nutrition can improve the state 
of your health, reducing the risk of many diseases, as well 
as chronic ones. But there are no dietary rules that are the same 
for everyone, just as there are no diets that work for everyone. 
FTO16 
16q12,2 
ACE17 
17q23.3 
APOC311 
11q23,3 
LPL8 
8p21,3 
MTHFR1 
1p36.22 
VDR12 
12q13.11 
GSTM1 
1p13.3 
GSTT22 
22q11.23 
CYP1A216 
15q24.1 
SOD6 
6q25,3 
IL101 
16q12,2 
TNFα6 
6q21,33 
ACE17 
17q23.3 
CYP1A216 
15q24.1 
VDR12 
12q13.11 
LCT2 
2q21.3 
DQ2/86 
6p21,32 
BODY FAT LEVELS 
AND SUGGESTED 
EXERCISE 
LIPIDS 
METABOLISM 
GLYCEMIC 
LEVELS + 
CABOHYDRATES 
METABOLISM 
B VITAMINS 
METABOLISM 
D VITAMINS 
METABOLISM 
Bone Health 
DETOXIFICATION 
ABILITY 
INFLAMMATORY 
RESPONSE 
SENSITIVITY 
TO SALT 
Hypertension 
SENSITIVITY 
TO CAFFEINE 
LACTOSE 
INTOLERANCE 
PREDISPOSITION 
TO CELIAC DISEASE 
Gluten Tolerance 
ACE17 
17q23.3 
PPARG3 
3p25,2 
TCF7L210 
10q25.2-3 
YOUR DNADiet [iD] 
With this test we have analyzed some variations present in 
16 GENES, which are involved in the metabolism of foods, 
and play an important role in determining your body health: 
• FATS ABSORBTION 
• LIPIDS AND GLUCOSE METABOLISM 
• FATS MOBILIZATION AND LIPIDS METABOLISM 
• FATS REGULATION AND BREAKDOWN OF FAT STORES 
• FATS METABOLISM AND BODY FAT LOSS 
• BONES HEALTH 
• SENSITIVITY TO CAFFEINE, ALCOHOL, SALT HYPERTENSION 
Science of [DNA] f(x)™ = [(1+1) x (1+224+3) x 3] = 127.800 
24 [iD]DNA ® 
INDIVIDUAL TREATMENT 
25 COMBINATIONS ultra-custom
The macroscopic appearance of cellulite is a result of alterations of the connective tissue, 
which bestow typically spongy and riddled features on the outer layer of skin, 
commonly known as orange peel. But not all cellulite is created equal. 
Cellulite is characterized by relief alterations of the skin surface, which give the skin 
an orange peel, cottage cheese, or mattress appearance. 
Flaccidity, laxity, or sagging of the skin further aggravates relief alterations. 
Scientific studies have shown that this type of imperfection may arise in very thin people, 
and that, on the contrary, some people who are overweight may not be affected by it. 
These data suggested that cellulite is not only linked to incorrect diet and lifestyle, but that 
genetic factors may also somehow be involved. 
EACH ONE OF US IS DIFFERENT, AND THESE DIFFERENCES ARE DUE, 
AT LEAST IN PART, TO OUR DNA THAT WITH ITS MINOR VARIATIONS 
ALLOWS US TO DIFFERENTIATE IN AT LEAST 3 RESPECTS: 
LET’S CALCULATE 
YOUR GENE-EXPRESSION 
CELLULITE GRADE 
Although cellulite is often associated a lack of fitness, 
ABOUT 90% OF WOMEN, including thin and athletic morphotypes, 
experiment some kind of cellulite. 
ESR16 
6p25.1 
IL-1a2 
2q13 
ACE17 
17q23.3 
HIF1α14 
14q23.2 
CYP1A27 
7q36,1 
HORMONAL FACTOR 
AND GENETIC 
PREDISPOSITION 
CELLULAR 
AND TISSUE 
INFLAMMATION 
OXYGENATION, 
VASODILATATION 
AND ALTERATION OF 
MICROCIRCULATION 
YOUR DNACell [iD] 
HORMONAL FACTORS 
Have a dominant role in the formation of cellulite. 
INFLAMMATION 
Contributes to increased levels of fluid in tissues. 
OXYGENATION-VASODILATION-ALTERATION 
OF THE MICROCIRCULATION 
Some genes may be associated with alterations of the venous 
system causing a slowing down of blood flow and stagnation 
of fluids in the spaces between cells. 
1 
2 
3 
Science of [DNA] f(x)™ = [2 x (144+3) x 3] = 230.514 
26 [iD]DNA ® 
INDIVIDUAL TREATMENT 
27 COMBINATIONS ultra-custom
Your genes play a key role in biological systems, 
like muscle formation, oxygenation of blood and tissues, 
and metabolism of lactic acid. Although you cannot 
change your genetic profile, you can benefit from your 
genetic advantages and maximise your potential. 
YOU CAN OVERCOME THE PAIN 
FROM INTENSE EXERCISE AND 
PRESSURE UNDER COMPETITION. 
YOU CAN BETTER AVOID INJURIES. 
Since the diet of athletes is a significant 
factor for their Performance, there will be 
DNADiet POWER and DNADiet ENDURANCE 
containing also genetic factors which 
affect athletes’s power and endurance 
performance nutritional needs. 
YOUR DNASport PERFORMANCE 
ANALYSES GENES FOR CERTAIN 
MUTATIONS ASSOCIATED 
WITH ATHLETIC PERFORMANCE, 
ALL DOCUMENTED IN SCIENTIFIC 
LITERATURE. 
SPORT 
PERFORMANCE 
ARE YOU BETTER SUITED 
TO SPORTS REQUIRING 
ENDURANCE, STRENGTH OR SPEED? 
Choose a sports that suits you. Learn how you can 
improve your sport performance, following you genetic advantages. 
Identify your athletic strengths and weaknesses. 
YOUR DNASport [iD] 
GDF5 
COL5a1 
SPORT 
INJURIES 
ADRB2 
AGT 
ACE 
BDRK2 
MSTN 
ACTN3 
VEGF 
PPARGα 
TRAINING 
& RECOVERY 
IL6R 
IL6 
CRP 
SOD2 
NOS 
28 [iD]DNA 29 ® 
ultra-custom
ARx 
Xq12 
EDA2Rx 
Xq12 
20p1120 
20p11 
GPX3 
3p21.31 
GENETIC 
PREDISPOSITION 
Andro-Genetic 
Alopecia 
OXIDATIVE 
STRESS HAIR 
LOSS 
YOUR DNAHair [iD] 
ARE YOU GENETICALLY 
PREDISPOSED TO HAIR LOSS? 
Your DNA determines when you start showing hair loss, if this is androgenetic alopecia 
or just stress, how quickly and at what rate your alopecia could worsen as becoming irreversible 
baldness, which is unique to you. 
Your DNAHair profile will detail your risk of irreversible androgenetic alopecia and the best 
corrective professional treatment, so that you can take action straight away. 
idna.works 
[iD]DNA® test, genetic report and treatments are not intended, and should not be used, to diagnose or treat any diseases or medical conditions. 
[iD]DNA® is a exclusive swiss patented pending concept, covered by international trademarks and intellectual property rights protection worldwide. 
[iD]DNA® and all its brands, trademarks, products and materials belong exclusively to Suisse Life Science SA and are to be used for informational purposes only. 
Science of [DNA] f(x)™ = [(1+1+1+1) x (174+2) x 3] = 1.002.276 
INDIVIDUAL TREATMENT 
COMBINATIONS 
30 [iD]DNA® 
ultra-custom
© 2014 all rights reserved - touts droits rèservès 
Suisse Life Science S.A. - SWITZERLAND 
www.suisselifescience.com 
THE FIRST 
DNA-PERSONALISED 
TREATMENT IN THE WORLD 
idna.works

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  • 2. WHAT WORKS FOR ONE PERSON, DOES NOT NECESSARILY WORK FOR ANOTHER PERSON. GENETICS CREATES A NEW CLASS OF SKINCARE TECHNOLOGY. We know that not every skincare product is going to suit everyone, no matter how much the cosmetic industry tells you. And this is why there are so many brands out there and literally thousands of different products. LIFE IS COMPLICATED, BUT BEAUTY DOESN’T HAVE TO BE. idna.works PERSONALISED REALLY PERSONALISED 3
  • 3. Science of [DNA] f(x)™ = GENES VS LIFESTYLE No more guesswork, no more buying products that feel like they might help. THERE IS NO ONE-SIZE FITS ALL FOR OUR CUSTOMERS. We replaced skincare guesswork with genetically-designed cosmeceuticals OTC (over the counter) and nutricosmetics supplements. THE RIGHT INGREDIENTS, IN THE RIGHT FORMULATIONS, IN THE RIGHT ORDER. Science of [DNA] f(x)™ proprietory statistical algorithms grows in accuracy day by day with [iD]DNA® growing sample set. 2014 population for Science of [DNA] f(x)™ is about more than 20.000 DNA population wide samples stored entirely in-house, making [iD]DNA® ultra-custom biologically active treatment leading the way in wellness personal genetics predictions. GENETICS VS LIFESTYLE [iD]DNA® ultra-custom IS SMART SCIENCE INDIVIDUAL TREATMENT PLANS THAT PERFORM AS THEY CLAIM A SIMPLE, ADVANCED, PERSONALISED TREATMENT PLAN SUITED FOR TODAY BUSY LIVES HOW MUCH OF YOUR SKIN AGING CAN YOU ACTUALLY CONTROL? While genetics do play a large role in how quickly you will age, recent research has started to show that the habits you develop and choices you make throughout life might be even more telling, so with your genetically customised ANTI-AGING plan you have control over how your skin ages. A PERSONALISED TREATMENT PLAN 4 [iD]DNA 5 ® ultra-custom
  • 4. WE FOCUS ON GENES VS LIFESTYLE: How much of your skin aging can you control? IF YOU WANT TO STAY YOUNG WITH AGE, YOU NEED TO KNOW YOUR GENE-EXPRESSION AGE. LET’S DISCOVER YOUR SKIN IDENTITY! FIGHT YOUR EXPIRATION DATE 6 [iD]DNA 7 ® ultra-custom
  • 5. THE DNA CODE IS THE KEY SCIENTIFIC APPROACH Aging is a gradual, irreversible process that occurs as a number of changes in the appearance and texture of the different skin structures. Your DNA is the code containing all the information necessary to our cells to develop over time [iD]DNA® IS THE FIRST DNA-PERSONALISED ANTI-AGING TREATMENT IN THE WORLD 8 [iD]DNA 9 ® ultra-custom
  • 6. STAY YOUNG WITH AGE! DO YOU REALLY KNOW IF YOU’RE YOUNGER OR OLDER THAN YOUR BIRTH-CERTIFICATE AGE? LET’S FOCUS ON GENES VS LIFESTYLE: How much of your aging can you really control? DNAge The first DNA-personalised prescription strength treatment to help you fight your SKIN AGING concerns on your GENE-EXPRESSION AGE. DNADiet The DNA-personalised weight loss management plan to help you manage successfully your weight on your GENE-EXPRESSION EATING PROFILE. DNACell The first DNA-personalised CELLULITE treatment to help you fight the severity stage of your GENE-EXPRESSION CELLULITE GRADE. DNAHair The DNA-personalised HAIR LOSS treatment to help you fight your GENE-EXPRESSION HAIR LOSS STAGE. DNASport The first DNA-personalised SPORT PERFORMANCE optimisation plan to help you choose the sport that best suits you and improve your performances to your maximum potential. TURN BACK THE CLOCK 10 [iD]DNA 11 ® ultra-custom
  • 7. 1 As you’ve done your simple DNA assessment, you’re ready to discover research-grade lifelong scientific remarks and suggestions. 2 3 This [iD] GUIDE comes with your [iD] GENETIC REPORT. Ask your consultant to fully understand any insight and connect to idna.works to create your [iD]DNA® 15 days-trial of your [iD]DNA® ultra-custom foundation treatment. Your very individual treatment: the right ingredients, intensity, dose, dosage and the right order depends on your [iD]DNA® score, a benchmark of individual GENES vs LIFESTYLE expression age. 4 IT’S TIME FOR YOUR TREATMENT TO GET PERSONAL ONE-SIZE DOES FIT YOU ULTRA-CUSTOM YOUR DNA TEST Do you want real results? [iD]DNA® ultra-custom, the first and only genetically-guided skincare treatment in the world. Specific deficits. Individual benefits. Precision skincare treatments. [iD]DNA® ASSESSMENT [iD]DNA® GENETIC REPORT [iD]DNA® ULTRA-CUSTOM BIOLOGICALLY ACTIVE TREATMENT Each [iD]DNA® treatment is engineered on scientific studies (in vivo) clinical efficacy terms of application and parameterised to individual GENES vs LIFESTYLE guidance. [iD]DNA® CHALLENGE Your follow up for evidence-based performance. [iD]DNA® technology measures your results and how much you could improve more... DNA-PERSONALISATION You’re unique and your beauty is unique, only a personalised treatment will work for you. [iD]DNA® ultra-custom is the luxury of a customised science-based skincare treatment made specifically for you. Because your genes don’t lie. GET RESULTS Forget trials and errors. Get results now! Your [iD]DNA® ultra-custom treatment plan will provide you: • THE RIGHT INGREDIENTS • THE RIGHT FORMULATIONS • THE RIGHT ORDER Prescription strength. With no need of prescription. THE TRUTH [iD]DNA® is the only concept to accept the challenge of proving on you the effectiveness of your personalised treatment. Change perspective, focus on GENES vs LIFESTYLE to calculate your gene-expression age (younger or older than your birth-certificate age?) REAL SCIENCE. REAL RESULTS. [iD]DNA® YOUR IDENTITY [iD]DNA® THE CONCEPT TREATMENT-PACK 60 days 2 months 120 days 4 months 120 days 6 months 240 days 8 months CONCERNS Anti-Aging Anti-Aging • Cellulite Treatment • Weight Loss Management • Body Contouring Cellulite Treatment • Weight Loss Management • Hair Loss Treatment Hair Loss Treatment 12 [iD]DNA 13 ® ultra-custom
  • 8. YOUR [iD] GENETIC REPORT HOW TO READ YOUR [iD] 2 6 YOUR [iD] GENETIC PROFILE Gene Cromosome Genotype FLG Filaggrin 1q21.3 II MMP3 Stromelysin-1 also called matrix metalloproteinase 3 11q22.2 5A/5A ELN Elastin 7q11.23 -/A PPARG Cellular receptor PPARG 3p25.2 CC SOD Superoxide dismutase 2 6q25.3 TC GSTT Glutathione S-transferase T-1 22q11.23 INS GSTM Glutathione S-transferase M-1 1p13.3 DEL NOS3 Endothelial nitric oxide synthase 7q36.1 5/5 TNFα Endothelial nitric oxide synthase α 6p21.33 GG EMILIN1 Emilin 1 2p23.3 CG COL3a1 Collagen 2q32.2 GG GPX Glutathione peroxidase 3p21.31 CT HAS1 Hyaluronic acid synthetase 19q13.41 GG GENETIC EVALUATION DECODING KEY OPTIMAL genetic function ALTERED genetic function ADVERSE genetic function GENE-EXPRESSION AGE Your [iD] DNA index* Determined upon the basis of genetic testing combined with your lifestyle self-optimisation [1] Wrinkling (firmness + elasticity) ………………………………………………………………………………………m……e…d……iu…m…… …r…is…k [2] Moisturisation (hyaluronic acid potential) ……………………………………………………………in…c……re……a…s…e…d… …r…is…k [3] Skin Hydration (hydro-lipid film) ……………………………………………………………………………………in…c…r…e…a……s…e…d… risk [4] Free radicals damage …………………………………………………………………………………………………………… medium risk [5] Regeneration (vascolarisation + oxygenation) …………………………………………………r…e…d…u…c……e d risk [6] Sensivity + Inflammation ………………………………………………………………………………………………………r…e…d…u…c……e…d… …r…is…k… … VISIBLE EFFECTS BIOLOGICAL EFFECTS soft skin[1] balanced tone and elasticity maintenance[1] potential premature skin aging[2] possible loss of subcutaneous fat on the face resulting in the appearance of wrinkles and skin folds[2] soft and shiny skin[3] proper hydration[3] possible sagging skin in the form of unsightly wrinkles or expression lines[6] possible predisposition to hypersensitive and reactive skin[6] 54% unaltered hydro-lipid film barrier protection[4] good protection against free radicals damage and oxidative stress[5] effective elimination of toxic substances[5] correct cell regeneration[1] protection against external agents[1] maintenance of firmness[1] possible alteration in the production of pro-inflammatory cytokines[2] risk of developing flogistic phenomena[2] fair hydrating ability[3] normal ability to retain water[3] insufficient intake of nitric oxide[6] possible minor defense and regeneration capabilities against exogenous stimuli[6] possible minor firmness of the dermis[6] [ ] brackets indicates the number of the area in which the effect of which it refers. 100 OPTIMAL + + Base level FOLLOW UP -- recommended 0 MAXIMUM RISK - - MAXIMUM SUPPORT recommended + + *[iD] DNA® index is the benchmark of the Swiss patent pending concept [iD] DNA® ultra-custom, showing your scoring in terms of GENES vs. LIFESTYLE. [iD] DNA® index is created on your genetics, balanced by the interference of individual habits by anamnestic self-assessment. Your area [iD] DNA® index will be processed by the Science of [DNA] f(x)™ to get your recommended treatment plan. The scale [iD] DNA® index ranges from 100 to 0. GENETICAL GUIDANCE FOR YOUR TREATMENT PLAN The genetic variant analyzed predispose to a reduced state of hydration. Your skin is less able to retain water, appearing less tonic. Your genetics also expose skin to the risk of developing intense dryness phenomena and loss of relaxing capacity. To counter the adverse effects to which your genetics predispose you it is important to follow few recommendations that may be useful to improve your state of hydration, delaying the onset of aging phenomena and helping skin remain firmer for longer. Given that intense exposure to UV rays coming from the sun may cause skin damage, it is recommendable to use sunscreens and avoid the hours of maximum intensity. UV rays are also emitted from sunlamps used in tanning treatments. The best international scientific references recommend you a corrective treatment based on these suggestions. Pentavitin® is a 100%-natural ingredient, made in Switzerland, ECOCERT, to feel deep hydration for 72 hours. Clinically tested to effectively stimulate genes that play a key role in skin barrier improvement.* Moreover, to improve the aspects analyzed in this area, the treatment should also include hyaluronic acid, sodium hyaluronate crosspolymer, biosaccharide gum-1. Strictly following the treatment plan that you can create with this genetical guidance, the [iD] DNA index® for SKIN MOISTURISATION will improve up to 36%. VISIBLE EFFECTS BIOLOGICAL EFFECTS POSSIBLE SAGGING SKIN IN THE FORM OF UNSIGHTLY WRINKLES OR EXPRESSION LINES POSSIBLE PREDISPOSITION TO HYPERSENSITIVE AND REACTIVE SKIN INSUFFICIENT INTAKE OF NITRIC OXIDE POSSIBLE MINOR DEFENSE AND REGENERATION CAPABILITIES AGAINST EXOGENOUS STIMULI POSSIBLE MINOR FIRMNESS OF THE DERMIS AREA [2] *all clinical data refers to in vitro ed in vivo clinical studies for claim substantiations by the manufacturers, from their product dossier. Data used for internal training on treatment functionalities and outcomes presentation. Available evidence documentation on request. SNP DETAIL Gene HAS1 Hyaluronic acid synthetase Hyaluronic acid bestows skin the particular properties of plasticity, strength, and shape retention thanks to its moisturizing ability. In fact, it is able to bind a large number of molecules of water, ensuring greater skin hydration. The presence of a polymorphism at this gene level, may contribute to a lesser state of hydration of skin. Your DNA test highlighted the presence of the disadvantageous GG variant which renders the HAS1 enzyme less functioning. The reduction of hyaluronic acid which follows causes skin to appear less hydrated, as it retains less water molecules. Cromosome Genotype 18 GG Locus Telomere localisation 18q13.41 13.41 AREA [2] DNA-RECOMMENDED ACTIVE INGREDIENTS CLINICAL PRESCRIPTION TOPICAL INGREDIENTS NUTRITIONAL INGREDIENTS ACETIL HEXAPEPTIDE-50 CAPRYLIC/CAPRIC TRIGLYCERIDE (AND) TEPRENONE CERAMIDE 3 (AND) CERAMIDE 6 II (AND) CERAMIDE 1 (AND) PHYTOSPHINGOSINE CHRYSANTHUS BULB EXTRACT COPPER TRIPEPTIDE-1 DIMETHILMETHOXY CHROMANOL GLYCOPROTEINS, GLUTAMIC ACID, VALINE, THREONINE SOY ISOFLAVONES ISOTHIOCYANATES L-ASCORBIC ACID 15% OZONIZED OLEIC ACID PHYTOCELLTEC MALUS DOMESTICA PROANTHOCYANIDIN PHOSPOLIPID COMPLEX TRIPEPTIDE-10 CITRULLINE HYALURONIC ACID SODIUM HYALURONATE CROSSPOLYMER BIOSACCHARIDE GUM-1 SACCARINE ISOMERATE DMAE-DIMETHYLAMINOETHANOL HYDROLIZED RICE PROTEIN, GLYCINE SOJA PROTEIN, SUPEROXIDE DISMUTASE OLIGOPEPTIDE-68 PALMYTOL TRIPEPTIDE-5 SUPEROXIDE DISMUTASE ACETYL TETRAPEPTIDE PLATINIUM NIACINAMIDE POLLEN EXTRACT (AND) GLYCINE SOJA GLYCINE SOYA PROTEIN (AND) SUPEROXIDE DISMUTASE (AND) SODIUM DEXTRAN SULFATE OLIGOPEPTIDE-34 ACETYL DECAPEPTIDE-3 ALPHA-LIPOIC ACID ELLAGIC ACID NIACIN (VITAMIN B3) SUPEROXIDE DISMUTASIS 560 UI VITAMIN C VITAMIN D BIOTIN (VITAMIN H) RECOMMENDED BIOACTIVE INGREDIENTS ACETIL HEXAPEPTIDE-50 Juveleven® is the guardian of your genomic integrity, by protecting and repairing DNA damage and delays senescence: cell rejuvenation by over 10 years*. Key element in preserving the vital code. Reverts senescence in fibroblasts. ACETYL DECAPEPTIDE-3 CG-Rejuline® is a bio-mimetic complex, which prevents the formation of expression lines and wrinkles, promoting active cell regeneration. It's a new technology that revitalise and regenerate your skin. CG-Rejuline® strengthens elasticity and improves skin quality, inducing the synthesis of collagen type I and elastin. ACETYL GLUTAMYL HEPTAPEPTIDE-1 SNAP-8® is a bio-mimetic epta-peptide safe hi-tech alternative solution to Botox®. Bye, bye Botox®: S NAP-8® r educes w rinkles u p t o - 6 3%, a fter 28 days application*, without needles. Maximum efficacy for frown lines, crow's feet, expression wrinkles. ACETYL HEXAPEPTIDE-8 Argireline® is a bio-mimetic hexapeptide, specific for the correction of eye contour concerns. It relieves congestion in the eye area; it is active against the formation of edema (swelling) caused by compromised hemodynamics, against faulty lymphatic circulation, or against high capillary permeability. This peptide regulates the loss of skin elasticity and the risk of formation of bags under the eyes. It also reduces dark circles. Clinical tests show that it reduces bags under the eyes in only 14 days*. ACETYL TETRAPEPTIDE PLATINIUM Platinum peptide is a bioconjugated high-tech nanoparticle clinically tested for +280% collagen III synthesis increase, +250% collagen I synthesis increase, -61% wrinkles reduction, +47% skin elasticity, +33% skin hydration, after just 30 days application*. ACETYL TETRAPEPTIDE-2 Uplevity® hi-tech peptide counteract the force of gravity, by increasing collagen and functional elastin synthesis, and cellular support. It provides a better structure to the dermis improving the quality of mature skin. Clinically tested for +47,3% collagen I synthesis, +21,7% elastin synthesis. Uplevity® peptide further contributes to skin firmness by overexpressing genes involved in cellular cohesion, that are the interface between the actin cytoskeleton and extracellular matrix (ECM)*. The ultra-personalized treatment plan on your genetic identity [1] Wrinkling (firmness + elasticity) …………………………………………………………………………………………m……e…d…i…u…m…… r…i…s k [iD] DNA index [iD] DNA index TARGET Your DNA reccommends 59% 69% The genetic test highlighted a reduced susceptibility to chrono-aging. This means that your skin properly protects against external agents and will tend to remain more supple, firm and soft. [2] Moisturisation (hyaluronic acid potential) ……………………………………………………………i…n…c…r…e…a…s…e……d risk [iD] DNA index [iD] DNA index TARGET Your DNA reccommends 24% 36% The genetic variant analyzed predispose to a reduced state of hydration. Your skin is less able to retain water, appearing less tonic. Your genetics also expose skin to the risk of developing intense dryness phenomena and loss of relaxing capacity. [3] Skin Hydration (hydro-lipid film) ……………………………………………………………………………………i…n…c…r…e…a…s…e…d…… r…i…s k [iD] DNA index [iD] DNA index TARGET Your DNA reccommends 30% 35% The genetic variant we detected predisposes to an increased accumulation of adipose tissue. Therefore you may experience alterations in the lipid film with typical manifestations of oily skin and acne. SCIENTIFIC REFERENCES 1. The important role of stratum corneum lipids for the cutaneous barrier function. van Smeden J, Janssens M, Gooris GS, Bouwstra JA. Biochim Biophys Acta. 2013 Nov 16. doi:pii: S1388-1981(13)00248-5. 10.1016/j.bbalip.2013.11.006. 2. Connective tissue biochemistry of the aging dermis. Age-associated alterations in collagen and elastin.Uitto J.Clin Geriatr Med. 1989 Feb;5(1):127- 47. Review. 3. Effect of the sun on visible clinical signs of aging in Caucasian skin. Flament F, Bazin R, Laquieze S, Rubert V, Simonpietri E, Piot B. Clin Cosmet Investig Dermatol. 2013 Sep 27;6:221-32. doi: 10.2147/CCID.S44686. 4. 5,7-Dimethoxyflavone, an activator of PPARα/γ, inhibits UVB-induced MMP expression in human skin fibroblast cells.Kim JK, Mun S, Kim MS, Kim MB, Sa BK, Hwang JK.Exp Dermatol. 2012 Mar;21(3):211-6. doi: 10.1111/j.1600-0625.2011.01435.x. 5. Peroxisomes in dermatology. Part I.Smith KJ, Dipreta E, Skelton H.J Cutan Med Surg. 2001 May-Jun;5(3):231-43. Epub 2001 May 17. Review. 6. The role of manganese superoxide dismutase in skin aging. Treiber N, Maity P, Singh K, Ferchiu F, Wlaschek M, Scharffetter-Kochanek K.Dermatoendocrinol. 2012 Jul 1;4(3):232-5. doi: 10.4161/derm.21819. 7. Effects of cigarette smoke extracts on the growth and senescence of skin fibroblasts in vitro. Yang GY, Zhang CL, Liu XC, Qian G, Deng DQ.Int J Biol Sci. 2013 Jun 28;9(6):613-23. doi: 10.7150/ijbs.6162. Print 2013. 8. Endothelial nitric oxide synthase mediates cutaneous vasodilation during local heating and is attenuated in middle-aged human skin. Bruning RS, Santhanam L, Stanhewicz AE, Smith CJ, Berkowitz DE, Kenney WL, Holowatz LA. J Appl Physiol (1985). 2012 Jun;112(12):2019-26. doi: 10.1152/japplphysiol.01354.2011. Epub 2012 Apr 12. 9. Nitric oxide function in the skin. Cals-Grierson MM, Ormerod AD.Nitric Oxide. 2004 Jun;10(4):179-93. Review. 10. Aging affects the association between endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction in the Korean male population.Park JE, Lee WH, Hwang TH, Chu JA, Kim S, Choi YH, Kim JS, Kim DK, Lee SH, Hong KP, Seo JD, Lee WR.Korean J Intern Med. 2000 Jan;15(1):65-70. 11. IL-11, IL-1α, IL-6, and TNF-α are induced by solar radiation in vitro and may be involved in facial subcutaneous fat loss in vivo. Li WH, Pappas A, Zhang L, Ruvolo E, Cavender D. J Dermatol Sci. 2013 Jul;71(1):58-66. doi: 10.1016/j.jdermsci.2013.03.009. Epub 2013 Apr 10. 12. Factors of skin ageing share common mechanisms. Giacomoni PU, Rein G.Biogerontology. 2001;2(4):219-29. Review. 13. Effect of the sun on visible clinical signs of aging in Caucasian skin. Flament F, Bazin R, Laquieze S, Rubert V, Simonpietri E, Piot B. Clin Cosmet Investig Dermatol. 2013 Sep 27;6:221-32. doi: 10.2147/CCID.S44686. 14. Loss-of-function polymorphisms in the filaggrin gene are associated with an increased susceptibility to chronic 15. irritant contact dermatitis: a case–control study C.M. de Jongh,*_ L. Khrenova,_ M.M. Verberk,* F. Calkoen,* F.J.H. van Dijk,* H. Voss,_ S.M. John_ and S. Kezic**Coronel Institute of Occupational Health, Academic Medical Centre, University of Amsterdam, P.O. Box 22700, Amsterdam 1100 DE, the Netherlands_National Poisons Information Centre, National Institute for Public Health and the Environment, Bilthoven, the Netherlands_Department of Dermatology, Environmental Medicine and Health Theory, University of Osnabru¨ck, Osnabru¨ck, Germany 16. Matrix metalloproteinase-3 genotype contributes to age-related aortic stiffening through modulation of gene and protein expression.Medley TL, Kingwell BA, Gatzka CD, Pillay P, Cole TJ.Circ Res. 2003 Jun 13;92(11):1254-61. Epub 2003 May 15. 17. Molecular pathology of the elastic fibers. Christiano AM, Uitto J. J Invest Dermatol. 1994 Nov;103(5 Suppl):53S-57S. Review. 18. Genotype-activity relationship for Mn-superoxide dismutase, glutathione peroxidase 1 and catalase in humans. Bastaki M, Huen K, Manzanillo P, Chande N, Chen C, Balmes JR, Tager IB, Holland N Division of Environmental Health Sciences, School of Public Health, University of California- Berkeley, Berkeley, CA 94608, USA. 19. Genotype-activity relationship for Mn-superoxide dismutase, glutathione peroxidase 1 and catalase in humans. 20. Bastaki M, Huen K, Manzanillo P, Chande N, Chen C, Balmes JR, Tager IB, Holland N. Division of Environmental Health Sciences, School of Public Health, University of California-Berkeley, Berkeley, CA 94608, USA. Arch Dermatol Res. 2011 Aug;303(6):445-9. doi: 10.1007/s00403- 011-1129-9. Epub 2011 Feb 4. GUIDANCE FOR YOUR TREATMENT PLAN variant analyzed predispose to a reduced state of hydration. Your skin is less able to appearing less tonic. Your genetics also expose skin to the risk of developing intense phenomena and loss of relaxing capacity. adverse effects to which your genetics predispose you it is important to follow few recommendations that may be useful to improve your state of hydration, delaying the onset of phenomena and helping skin remain firmer for longer. intense exposure to UV rays coming from the sun may cause skin damage, it is to use sunscreens and avoid the hours of maximum intensity. UV rays are also sunlamps used in tanning treatments. international scientific references recommend you a corrective treatment based on these 100%-natural ingredient, made in Switzerland, ECOCERT, to feel deep hydration Clinically tested to effectively stimulate genes that play a key role in skin barrier improve the aspects analyzed in this area, the treatment should also include sodium hyaluronate crosspolymer, biosaccharide gum-1. following the treatment plan that you can create with this genetical guidance, the [iD] SKIN MOISTURISATION will improve up to 36%. EFFECTS BIOLOGICAL EFFECTS SKIN IN THE FORM OF UNSIGHTLY WRINKLES LINES PREDISPOSITION TO HYPERSENSITIVE AND REACTIVE INSUFFICIENT INTAKE OF NITRIC OXIDE POSSIBLE MINOR DEFENSE AND REGENERATION CAPABILITIES AGAINST EXOGENOUS STIMULI POSSIBLE MINOR FIRMNESS OF THE DERMIS in vitro ed in vivo clinical studies for claim substantiations by the manufacturers, from their product dossier. Data used for internal training on treatment outcomes presentation. Available evidence documentation on request. [iD]DNA® REPORT 1 5 3 7 4 8 Your [iD] starts with your [iD]DNA® score. All the relevant areas in terms of biological systems affecting the concerns are detailed with visible and biological (internal) effects. Rather than simply focus on an analysis of your skin health, your [iD]DNA® provides active ingredients recommendations, directly related to your individual requirements. In your [iD] GENETIC REPORT, you find: • GENETIC remarks • LIFESTYLE recommendations • EXERCISE suggestions • NUTRITION recommendation • ACTIVE INGREDIENTS that suits most your skin. [iD]DNA® reveals you the improvement you can experience following your [iD]DNA® ultra-custom biologically active treatment. Follow the suggestions to get results! This is your genetic profile. All the SNPs involved are presented in detail with your genotype and an easy-to-understand positive/negative rating. Our scientific references library is able to define the relationship between the active ingredients and the different genes variations of your genetic profile. The scientific foundation uncovers your skin potential. Real science application reveals your human genomic profile, for more accurately predicting your treatment. [iD]DNA® is scientifically backed by third parties scientific references, you can find and check at the end of your [iD] GENETIC REPORT. 14 [iD]DNA 15 ® ultra-custom
  • 9. PREMIUM SWISS SKIN CARE TECHNOLOGY THE SCIENCE OF AGELESS SKIN: 3+5 REPAIRS, REJUVENATES AND TRANSFORMS SKIN. 1 1 2 2 IN&OUT BENEFITS: + CLINIAge NUTRICOSMETIC A DNA-personalised and professional-optimized skin care system designed to work in sinergy at the cellular level to help improve and preserve the youthful look and vitality of your skin. • PROTECT SKIN STEM CELLS • REPAIR DNA • SMOOTH OUT WRINKLES FROM THE INSIDE OUT • PROTECT THE YOUTHFUL LOOK AND VITALITY OF YOUR SKIN Just insert your [iD] code to find out you DNA-personalised treatment: FUNCTION AGE-DEFYING PRECISION CORRECTIVE INVERTAGE AVERAGE DURATIONS 60 days 2 months treatment 60/120 days 2-4 months treatment 120 days 4 months treatment 240 days 6 months treatment IN&OUT SUGGESTED OPTIONAL SUGGESTED MANDATORY AGE DEFYING SKINCARE CLEANSE FOUNDATION TREATMENT: CLINILift + PRESCRIPTION STRENGTH: booster PRECISION TREATMENT: CLINIUV A-B CLEANSE FOUNDATION TREATMENT: CLINICo2A, CLINICo2B FOUNDATION TREATMENT: CLINIGf DNA + PRESCRIPTION STRENGTH: booster PRECISION TREATMENT: CLINIEye_5 INTENSIVE CARE: CLINIFace (Eye) therapy 3 3 4 5 every 2 weeks every 10 weeks YOUR [iD]DNA® FORGET TRIALS AND ERRORS GET RESULTS NOW! [iD]DNA® ultra-custom represents an unprecedented approach to skin care. Your personalized skin care program started with your [iD]DNA® test. • BY TAKING THIS SIMPLE TEST, you unlock the secrets to your skin’s genetic strengths and weaknesses. • BY TESTING YOUR DNA, now you can scientifically select the professional strength treatment that will most benefit your skin’s beauty and health. ENJOY YOUR 15 DAYS DNA-PERSONALIZED FOUNDATION TREATMENT TODAY! AFTER YOUR FIRST 15 DAYS TREATMENT, TO GET YOUR FULL DNA-PERSONALISED TREATMENT: connect right now to idna.works just enter your [iD]code select the signs of aging you want to fight in YOU+online adjustement It’s easier than you think and it takes only 5 minutes. 1 2 3 idna.works idna.works 16 [iD]DNA 17 ® ultra-custom
  • 10. CLINICare® CLINICEUTICALS CLINICare® cliniceuticals is our brand of unique formulations for genetically-guided individual treatments, built just for the [iD]DNA® ultra-custom concept. + PATENTED SCIENCE + PROPRIETARY FORMULATIONS Proprietary formulations Scientifically formulated from researchers for targeted efficacy ALL THE ACTIVE INGREDIENTS ARE SELECTED TO ENSURE AN UNPRECEDENTED COSMETOGENOMICS EFFICACY: EXTENDS CELL VITALITY AND LONGEVITY Reactivating cells regeneration and renewal in the basal layer of epidermis, leading to a higher keratinocyte production. The epidermal tissue becomes thicker, denser and more resistant to external aggressions. STRENGTHENS THE EXTRACELLULAR MATRIX Restoring the dermo-epidermal junction and stimulates fibroblasts achieving an increase in the quality and amount of collagen and elastin. The skin recovers elasticity and firmness, facial oval has a new sustain and expression lines decrease substantially. CELL REGENERATION AND REPAIR Protecting and reactivating your own dermoepidermal stem cells, with selected biomimetic peptides and plant stem cells extracts, strengthening the connective tissue structure an improving skin quality and texture. INTELLIGENT ANTIOXIDANT ACTION Neutralising free radicals contributing to improve the skin’s defence capacity and delays the skin aging process. HIGH-TECH COSMETIC ENGINEERING Encapsulating biomimetic peptides, functional ingredients, plant stem cells in release biovectors to transport them and act in the innermost skin. They mimics, in their composition and structure, the cell membrane, increasing the penetration and diffusion levels. 18 [iD]DNA 19 ® ultra-custom
  • 11. To make you sure about getting the best results of your [iD]DNA® ultra-custom biologically active treatment, we put your smartphone in charge as your personal assistant: COMBINATION THERAPY DNA ASSESSMENT ACTIVE TREATMENTS cliniceuticals FOLLOW UP cliniceuticals check your [iD]DNA® ultra-custom treatment plan: THE RIGHT INGREDIENTS THE RIGHT FORMULATIONS THE RIGHT ORDER [iD]DNA® ultra-custom app will remind you all your treatments with your personalized dose, at the right moment. COLLECTIONS ANTI-WRINKLE TIGHTEN & LIFT REJUVENATION PRECISION professional strength ACTIVE INGREDIENTS TRYLAGEN® functional SNAP-8® peptide MATRIXYL-3000® peptide JUVELEVEN® peptide UPLEVITY® peptide RELISTASE® peptide DMAE EGF COPPER-peptide 1 PLATINUM-peptide REJULINE® peptide PREREGEN® functional ARGIRELINE® peptide BONT-peptide® SYN-AKE® peptide SENESTEM® functional DERMCOM® functional BENEFITS • diminishes length and depth of lines and wrinkles • stimulates collagen regeneration for healthy, younger looking skin • tightens and firms skin • restores elastin to create lift and contour • intelligent antioxidant action • free radicals and sun damage protection, DNA repair • moisturisation and skin protection • renew skin smoothness • refine skin texture • reveal skin radiance • revitalize skin tone • intelligent antioxidant action • correct eye bags, puffy eyes SUSTAINABLE SAFE HI-TECH COSMECEUTICALS PARABEN PHTALATE SLS COMEDOGENIC FREE NO ANIMAL INGREDIENTS ARTIFICIAL COLORS AGE-DEFYING SKINCARE SCIENCE OF [DNA] WHAT NEXT? YOUR TREATMENT AT YOUR FINGERTIPS! SEE THE REAL RESULTS! [iD]DNA® CHALLENGE When you’re about to end your treatment, your [iD]DNA® follow up WILL CHECK YOUR REAL IMPROVEMENT to show how your treatment has really worked. 20 [iD]DNA 21 ® ultra-custom
  • 12. With the passage of time, the skin may experience skin aging, id est a series of physiological changes that lead to an increased occurrence of micro-wrinkles, loss of elasticity, and skin dryness. These changes are mainly due to two parallel events: CHRONOLOGICAL AGING and ENVIRONMENTAL FACTORS. CHRONO-AGING depends on genetic factors specific to each of us. It begins after the age of 25, and it may be visibly manifested from 40 years onwards. We observe at the level of the epidermis a lower ability of cells to regenerate with consequent thinning of the skin layer. Even the skin glands are gradually reducing their activity, resulting in reduced production of sebum and increased skin dryness. Aging is also induced by environmental factors such as pollution, stress, unbalanced diets or exposure to irritants and harmful substances such as cigarette smoke. in particular, a very important role is played by PHOTO-AGING, which is a chronic and premature aging of the skin due to prolonged exposure to sunlight and to the formation of free radicals. Today, aging is worsen by TECHNOLOGICAL-AGING, the aging process caused by electromagnetic waves of iphones, mobile phones, ipads,computers, constantly attacking skin moisturisation and hydration barrier. WRINKLING Firmness + Elasticity MOISTURISATION Hyaluronic Acid Potential HYDRATION BARRIER Hydrolipid Film REGENERATION Vascolarisation + Oxigenation SENSITIVITY + INFLAMMATION BEFORE AFTER FREE RADICALS DAMAGE FLG1 1q21,3 MMP311 11q22,2 ELN7 7q11,23 EMILIN12 2p23,3 COL3a1 2q32,2 HAS119 19q13,41 PPARG3 3p25,2 SOD6 6q25,3 GSTM1 1p13,3 GSTT22 22q11,23 GPX3 3p21.31 NOS37 7q36,1 TNFα6 6q21,33 LET’S CALCULATE YOUR GENE-EXPRESSION AGE Are you younger or older than your birth-certificate age? Everyone’s skin is unique, as are their fingerprints and genetic code. Your biological and emotional life can be read on your skin. Your skin talks your story. YOUR DNAge [iD] Science of [DNA] f(x)™ = [(1+1) x (8+324+1) x 3)] + 2 = 6.291.512 22 [iD]DNA ® INDIVIDUAL TREATMENT 23 COMBINATIONS ultra-custom
  • 13. Nutrigenetics is a new discipline that seeks to explain how the substances we ingest are metabolized and used, based on our genes. The study of DNA makes it possible to determine the exact amount of nutrients that each of us requires and the reaction you’ve to different dietary components. DNADiet IS NOT A DIETARY PLAN DNADiet PROVIDES SPECIFIC NUTRITIONAL RECOMMENDATIONS FROM YOUR DNA No more dieting, but healthy eating: know yourself to take care of yourself CAN YOU EAT WHAT YOU LIKE, MANAGING SUCCESS-FULLY YOUR WEIGHT? It is scientifically proven that good nutrition can improve the state of your health, reducing the risk of many diseases, as well as chronic ones. But there are no dietary rules that are the same for everyone, just as there are no diets that work for everyone. FTO16 16q12,2 ACE17 17q23.3 APOC311 11q23,3 LPL8 8p21,3 MTHFR1 1p36.22 VDR12 12q13.11 GSTM1 1p13.3 GSTT22 22q11.23 CYP1A216 15q24.1 SOD6 6q25,3 IL101 16q12,2 TNFα6 6q21,33 ACE17 17q23.3 CYP1A216 15q24.1 VDR12 12q13.11 LCT2 2q21.3 DQ2/86 6p21,32 BODY FAT LEVELS AND SUGGESTED EXERCISE LIPIDS METABOLISM GLYCEMIC LEVELS + CABOHYDRATES METABOLISM B VITAMINS METABOLISM D VITAMINS METABOLISM Bone Health DETOXIFICATION ABILITY INFLAMMATORY RESPONSE SENSITIVITY TO SALT Hypertension SENSITIVITY TO CAFFEINE LACTOSE INTOLERANCE PREDISPOSITION TO CELIAC DISEASE Gluten Tolerance ACE17 17q23.3 PPARG3 3p25,2 TCF7L210 10q25.2-3 YOUR DNADiet [iD] With this test we have analyzed some variations present in 16 GENES, which are involved in the metabolism of foods, and play an important role in determining your body health: • FATS ABSORBTION • LIPIDS AND GLUCOSE METABOLISM • FATS MOBILIZATION AND LIPIDS METABOLISM • FATS REGULATION AND BREAKDOWN OF FAT STORES • FATS METABOLISM AND BODY FAT LOSS • BONES HEALTH • SENSITIVITY TO CAFFEINE, ALCOHOL, SALT HYPERTENSION Science of [DNA] f(x)™ = [(1+1) x (1+224+3) x 3] = 127.800 24 [iD]DNA ® INDIVIDUAL TREATMENT 25 COMBINATIONS ultra-custom
  • 14. The macroscopic appearance of cellulite is a result of alterations of the connective tissue, which bestow typically spongy and riddled features on the outer layer of skin, commonly known as orange peel. But not all cellulite is created equal. Cellulite is characterized by relief alterations of the skin surface, which give the skin an orange peel, cottage cheese, or mattress appearance. Flaccidity, laxity, or sagging of the skin further aggravates relief alterations. Scientific studies have shown that this type of imperfection may arise in very thin people, and that, on the contrary, some people who are overweight may not be affected by it. These data suggested that cellulite is not only linked to incorrect diet and lifestyle, but that genetic factors may also somehow be involved. EACH ONE OF US IS DIFFERENT, AND THESE DIFFERENCES ARE DUE, AT LEAST IN PART, TO OUR DNA THAT WITH ITS MINOR VARIATIONS ALLOWS US TO DIFFERENTIATE IN AT LEAST 3 RESPECTS: LET’S CALCULATE YOUR GENE-EXPRESSION CELLULITE GRADE Although cellulite is often associated a lack of fitness, ABOUT 90% OF WOMEN, including thin and athletic morphotypes, experiment some kind of cellulite. ESR16 6p25.1 IL-1a2 2q13 ACE17 17q23.3 HIF1α14 14q23.2 CYP1A27 7q36,1 HORMONAL FACTOR AND GENETIC PREDISPOSITION CELLULAR AND TISSUE INFLAMMATION OXYGENATION, VASODILATATION AND ALTERATION OF MICROCIRCULATION YOUR DNACell [iD] HORMONAL FACTORS Have a dominant role in the formation of cellulite. INFLAMMATION Contributes to increased levels of fluid in tissues. OXYGENATION-VASODILATION-ALTERATION OF THE MICROCIRCULATION Some genes may be associated with alterations of the venous system causing a slowing down of blood flow and stagnation of fluids in the spaces between cells. 1 2 3 Science of [DNA] f(x)™ = [2 x (144+3) x 3] = 230.514 26 [iD]DNA ® INDIVIDUAL TREATMENT 27 COMBINATIONS ultra-custom
  • 15. Your genes play a key role in biological systems, like muscle formation, oxygenation of blood and tissues, and metabolism of lactic acid. Although you cannot change your genetic profile, you can benefit from your genetic advantages and maximise your potential. YOU CAN OVERCOME THE PAIN FROM INTENSE EXERCISE AND PRESSURE UNDER COMPETITION. YOU CAN BETTER AVOID INJURIES. Since the diet of athletes is a significant factor for their Performance, there will be DNADiet POWER and DNADiet ENDURANCE containing also genetic factors which affect athletes’s power and endurance performance nutritional needs. YOUR DNASport PERFORMANCE ANALYSES GENES FOR CERTAIN MUTATIONS ASSOCIATED WITH ATHLETIC PERFORMANCE, ALL DOCUMENTED IN SCIENTIFIC LITERATURE. SPORT PERFORMANCE ARE YOU BETTER SUITED TO SPORTS REQUIRING ENDURANCE, STRENGTH OR SPEED? Choose a sports that suits you. Learn how you can improve your sport performance, following you genetic advantages. Identify your athletic strengths and weaknesses. YOUR DNASport [iD] GDF5 COL5a1 SPORT INJURIES ADRB2 AGT ACE BDRK2 MSTN ACTN3 VEGF PPARGα TRAINING & RECOVERY IL6R IL6 CRP SOD2 NOS 28 [iD]DNA 29 ® ultra-custom
  • 16. ARx Xq12 EDA2Rx Xq12 20p1120 20p11 GPX3 3p21.31 GENETIC PREDISPOSITION Andro-Genetic Alopecia OXIDATIVE STRESS HAIR LOSS YOUR DNAHair [iD] ARE YOU GENETICALLY PREDISPOSED TO HAIR LOSS? Your DNA determines when you start showing hair loss, if this is androgenetic alopecia or just stress, how quickly and at what rate your alopecia could worsen as becoming irreversible baldness, which is unique to you. Your DNAHair profile will detail your risk of irreversible androgenetic alopecia and the best corrective professional treatment, so that you can take action straight away. idna.works [iD]DNA® test, genetic report and treatments are not intended, and should not be used, to diagnose or treat any diseases or medical conditions. [iD]DNA® is a exclusive swiss patented pending concept, covered by international trademarks and intellectual property rights protection worldwide. [iD]DNA® and all its brands, trademarks, products and materials belong exclusively to Suisse Life Science SA and are to be used for informational purposes only. Science of [DNA] f(x)™ = [(1+1+1+1) x (174+2) x 3] = 1.002.276 INDIVIDUAL TREATMENT COMBINATIONS 30 [iD]DNA® ultra-custom
  • 17. © 2014 all rights reserved - touts droits rèservès Suisse Life Science S.A. - SWITZERLAND www.suisselifescience.com THE FIRST DNA-PERSONALISED TREATMENT IN THE WORLD idna.works