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Hydrolysing Agents
Water- Highly reactive substrates are readily and
completely hydrolyzed by water alone.
Eg: Grignard reagents
Diazonium Chlorides
Acid anhydrides
3
Hydrolyzing
Agents
Acids-accelerates hydrolysis
reactions eg: HCl, H2SO4
Alkali
a)Dilute alkali- used in hydrolysis of esters ,amides,fats etc.
Saponification-Hydrolysis of fats and oils by NaOH
b) Concentrated alkali- Excess alkali at high pressure and concentration can cause hydrolysis
at primary and secondary C-Cl linkages.
C6H5-Cl+NaOH C6H5-OH +NaOH C6H5-ONa+H2O
C)Alkali fusion- Concentration of alkali very high: Product formed will be in the form of
sodium salt and acidification is needed for obtaining the desired product.
Used in the preparation of phenols and sulphonic acids.
Enzymatic Hydrolysis- important in biological systems
Molasses invertase glucose+ fructose zymase ethyl alcohol
6
7
8
9
10
Thank You

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Hydrolyzing agents upload

  • 3. Water- Highly reactive substrates are readily and completely hydrolyzed by water alone. Eg: Grignard reagents Diazonium Chlorides Acid anhydrides 3 Hydrolyzing Agents
  • 5. Alkali a)Dilute alkali- used in hydrolysis of esters ,amides,fats etc. Saponification-Hydrolysis of fats and oils by NaOH b) Concentrated alkali- Excess alkali at high pressure and concentration can cause hydrolysis at primary and secondary C-Cl linkages. C6H5-Cl+NaOH C6H5-OH +NaOH C6H5-ONa+H2O C)Alkali fusion- Concentration of alkali very high: Product formed will be in the form of sodium salt and acidification is needed for obtaining the desired product. Used in the preparation of phenols and sulphonic acids. Enzymatic Hydrolysis- important in biological systems Molasses invertase glucose+ fructose zymase ethyl alcohol
  • 6. 6
  • 7. 7
  • 8. 8
  • 9. 9
  • 10. 10