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1. PG DEPARTMENT OF BIOTECHNOLOGY
SAHYADRI SCIENCE COLLEGE SHIVMOGGA
SEMINOR TOPIC
HUMAN KARYOTYPE
Guided by Presentation by
Nagaveni M R
I MSC (I SEMESTER)
PG department of biotechnology
Sahyadri science college shivmogga
Guided by
Mrs Asha S K
Lecturer
PG Department of
biotechnology
Sahyadri science college

2. CONTENTS
INTRODUCTION
HISTORY
• CHROMOSOMES
CELL CYCLE
HUMAN KARYOTYPE
• ADVANTAGES
AND
DISADVANTAGES
CONCLUSION
• REFERENCES

3. INTRODUCTION
KARYOTYPE: -
Karyotype are classified into two groups:-
1. Symmetric Karyotype
2. Asymmetric karyotype
Karyotyping
Karyogram
Karyology

4. HISTORY
THEOPHILUS PAINTER TJIO AND ALBERT LEVAN
(1921)

5. CHROMOSOME

6. CLASSIFICATION
Classification of chromosomes on the basis of the
centromere:-
1. Metacentric
2. Submetacentric
3. Acrocentric
4. Telocentric

7. 1.METACENTRIC
2. SUBMETACENTRIC

8. 3.ACROCENTRIC
4.TELOCENTIC

9. CELL CYCLE:-

10. HUMAN KARYOTYPE

13. ADVANTAGES
• Detection 0f chromosomal abnormalities
• Identification of genetic disorders
• Identify loss and addition chromosomes
• Gender identification
DISADVANTAGES
• Technique only allows for diagnosis and not cure
• Time consuming process
• The test like amiocentesis and CVS are both risky
an stressful for mother.

14. CONCLUSION
Human karyotype analysis typically involves
identifying the total number of chromosomes
present, checking for any abnormalities such as
missing or extra chromosomes, analyzing the
structure of each chromosome and determining the
gender of individual based on the sex
chromosomes.

15. REFERENCES
• P.K GUPTA .Cll and molecular biology fifth revised
edition.
• Verma P.S & Agarwal V.K. Genetics,9th Edition.