Biophysical chemistry is the study of biological systems and molecules using concepts from physics and physical chemistry. It examines biological structures and processes at the molecular level using techniques from physical chemistry. This includes investigating properties of biomolecules, molecular interactions in living cells, membrane structures, and molecular motors. Biophysical chemistry differs from biophysics which employs physics to study whole organisms and ecosystems, and biochemistry which focuses on the roles and functions of biomolecules. Examples of how biophysical chemistry integrates physics, chemistry and biology include using thermodynamics to study enzyme action and molecular imaging to visualize atomic structures and photosynthesis.

1. Biophysicalchemistry-Howbiology,
chemistryandphysicsarerelated..?
An introduction and overview
By
Shubhangi suri and Hinan -U- Nisa
B.tech students
SMVD university kakryal, J&K

2. What is a biophysical chemistry ??
It is a physical science that uses the concept
of physics and physical chemistry for the
study of biological systems.

3. BIOPHYSICALCHEMISTRY
Study of physical
properties of
biological
macromolecules at
either—
2. More global
structural level.
1. Chemical
sequence level.

4. BIOPHYSICAL CHEMISTRY.....
AN INTERFACE
PHYSICS BIOLOGY CHEMISTRY
BIOPHYSICAL
CHEMISTRY

5. INTRODUCTION

6. Biophysical chemistry.....its different
This course is different from BIOPHYSICS or BIOCHEMISTRY
BIOPHYSICS
•It is an interdisciplinary science that employs and develops theories and methods of the
physical sciences for the investigation of biological systems. Studies span all levels of
biological organization, from the molecular scale to whole organisms and ecosystems.
BIOCHEMISTRY
•It is study of chemical substances and vital processes occurring in living organisms .
Biochemists focus heavily on role, function and structure of biomolecules.
Biophysical
chemistry
•Biophysical chemistry employ various techniques used in physical chemistry to probe
the structure of biological systems.

7. Example relating physics, chemistry &
biology
Physical laws or concepts such as—
• Mechanics
• Hydrodynamics
• Optics
• Electrodynamics and Thermodynamics.
are used to explain biological processes
(physiologically) such as—
• Muscle contraction
• Neural communication
• Vision

8. INTERFACE OF PHYSICSAND BIOLOGY
We don’t yet know quite what a
physics of biology will consist of. But
we won’t understand life without it.

9. INTERFACE OF PHYSICS AND BIOLOGY
Basic concepts and laws of modern physics and
chemistry are directly relevant to biology.
Physics helps to understand how an organism
can create a biological memory of some
variable condition .

10. INTERFACE OF PHYSICS AND BIOLOGY
o Biological physics uses the tools and techniques
of physics to understand inner workings of the
machinery found in living organisms.
o It includes investigation into fluctuations in
biological systems, imaging of molecular motion,
the physical mechanisms of molecular motors,
properties of biological macromolecules,
interactions in living cells, bio membrane
structure and functions, mechanical properties of
chromosomes, etc.

11. EXAMPLES RELATING PHYSICS AND
BIOLOGY
Many flowers arrange their seeds or petals in a fibonacci like sequence to
maximize exposure to light and nutrients.
Biology helped scientists come up with the law of conservation of energy.
Bats use sound waves to navigate in the dark.
Wings give insects and birds the ability to move through the air.
Microscopy has made possible to resolve structures in biological cells at spatial
resolution of a few nanometre and observe dynamical processes with a temporal
resolution of millisecond to microsecond.

12. EXAMPLES RELATING PHYSICS AND
BIOLOGY
Ventilators are possible
because of fluid pressure
and pulse frequency so that
ventilation rate & amount
of pressure is suitable.
Optical traps are used to
stretch , twist and unzip
individual DNA molecules.

13. TECHNIQUES OR APPLICATIONS OF
PHYSICS USED FOR BIOLOGY

14. TECHNIQUES OR APPLICATIONS OF
PHYSICS USED FOR BIOLOGY
• Use the principle of magnetism
to take high quality images of
inside human body
MRI (magnetic
resonance
imaging)—
• Take images of skeletal
structure of body
X-ray –

15. Thermodynamics in Biophysical
chemistry

16. INTERFACE OF CHEMISTRY AND
BIOLOGY

17. EXAMPLES RELATING CHEMISTRY AND
BIOLOGY
Enzyme action can be explained in terms of the shape of a
pocket in the protein molecule that matches the shape of
the substrate molecule due to its binding of a metal ion.
Organic and inorganic molecules and ions are used to
synthesize proteins.
Helps to investigate the causes and cures of diseases.
Study how to maintain health wellness and study the
effects of nutritional deficiencies.

18. EXAMPLES RELATING CHEMISTRY AND
BIOLOGY

19. Molecular imaging in Biophysical
chemistry

20. Atomic structure in Biophysical
chemistry

21. Photosynthesis in Biophysical
chemistry

22. CONCLUSION
The principle behind is a PHYSICS,
The reactions undergoing is a CHEMISTRY,
AND
The resultant obtained is BIOLOGY
Or for BIOLOGICAL Purposes.

23. IN SHORT , EVERY PROCESS
HAPPENING , NEEDS
COORDINATION OF PHYSICS ,
CHEMISTRY AND BIOLOGY.

24. THANK YOU