High HIV Seropositivity among Heterosexuals
         at Risk in Miami Confirmed
     by Two Different Sampling Methods

      David W. Forrest, Gabriel A. Cardenas, Marlene LaLota,
            Dano W. Beck, Lisa R. Metsch, Xierong Wei,
      Jeffrey A. Johnson, S. Michele Owen, Thomas M. Liberti

                National HIV Prevention Conference 2011
                               Atlanta, GA
                            August 15, 2011
National HIV Behavioral Surveillance (NHBS)
   NHBS is a repeated, cross-
    sectional study of high-risk
    populations in US MSAs
   Target population rotates
    each year
      MSM
      IDU
      Heterosexuals at increased risk of HIV
       infection
   First round (2004-2007) conducted in Miami-
    Dade and Broward counties
   Second round (2008-2010) in Miami only
NHBS Objectives
"Effective HIV prevention programs rely primarily on changing behavior;
  therefore, behavioral data are needed to inform these programs.” [1]

         NHBS provides data on trends in:
           Risk behaviors
           HIV testing behaviors
           Use and impact of prevention
            services
           HIV prevalence and incidence
   [1] Lansky A, Abdul-Quader AS, Cribbin M, et al. Developing an HIV behavioral surveillance system for
        injecting drug users: the National HIV Behavioral Surveillance System. Public Health Reports 2007;
        122(suppl 1):48-55.
Target Population for
            NHBS-HET

• The NHBS-HET1 and HET2 cycles
  targeted heterosexually active adults in
  areas with high poverty in Miami-Dade
  County, Florida.
NHBS-HET Eligibility Criteria

 Eligible for study participation
    18-50 years of age for HET1, 18-60 years of
     age for HET2
    Resident of Miami-Dade County
    Male or Female (not transgender)
    First-time participant during cycle
    Able to complete interview in English or Spanish
Assessing Characteristics of
Population X In ON-going surveillance
Interviewing Van
NHBS-HET Samples
HET-1
•Data collected through venue-based sampling
•March 2007 – October 2007
•Miami total sample N=668 HET

HET-2
•Data collected through respondent-driven sampling
•July 2010 – November 2010
•Miami total sample N=568 HET
HET Samples for Analysis
Any NHBS-HET participants reporting
injection drug use (IDU) and any male
participants reporting sex with another
male (MSM) in their lifetimes were
excluded from this analysis.
            N=577 for HET1
            N=456 for HET2
Demographics of HET1 & HET2
                            HET1     HET2
   African American         80.59%   77.85%
     Lower income           70.72%   87.06%
      (<=$14,999)
High school education        79%     78.73%
       or less
 No health insurance        59.34%   58.41%
No visit to a health care   50.78%   46.49%
  provider in past 12
         months
Arrested in the previous    30.16%   22.37%
       12 months
Drug use and sexual risk
     behaviors of HET1 & HET2
                                  HET1     HET2
      Heavy alcohol use           26.9%    34.2%
        Illicit drug use          47.7%    56.36%
 Alcohol or drug treatment in     26.52%   33.77%
           lifetime
Depression (CES-D 10 scale)       39.17%   52.19%
     Unprotected vaginal          83.5%    87.5%
       and/or anal sex
HIV testing during the previous   58.5%    55.2%
          12 months
HIV among HET1 & HET2

                                 HET1     HET2

HIV positive (HIV test result)   5.7%     7.7%
Previously undiagnosed HIV       42.4%     37%
   (self reported HIV- or
  unknown plus HIV+ test
           result)
Previously undiagnosed who       85.71%   76.92%
reported unprotected vaginal
  or anal sex in the past 12
           months
HIV in NHBS-HET1


HIV positive test results were associated in
            the HET1 sample with:
    • Crack use in the past 12 months
       14.93% vs 4.52% (p=.001)
   • Self reported Hepatitis C infection
           20% vs 5.5% (p=.051)
HIV in NHBS-HET2
   HIV positive test results were
associated in the HET2 sample with:
          • Female gender
      11.6% vs 3.6% (p=.001)
 • Crack use in the past 12 months
     19.35% vs 5.84% (p<=.001)
• Self reported Hepatitis C infection
      23.53% vs 6.96% (p=.011)
Recent HIV Infection

Results of tests for recent HIV infection
   which exclude 12 month MSM and
 IDU show that 4.5% of the positives in
    HET1 and 7.1% in HET2 were
    infected within the previous 12
                 months.
Conclusions

Our findings document the high rates of heterosexually
 acquired HIV infection in lower-income communities in
   Miami using two different sampling strategies and
   underscore the need to increase and optimize HIV
          testing and other prevention services.
Limitations
 Data are predominantly self-reported and
  subject to recall bias
 Data are cross sectional and time order
  cannot be established
 Findings can only be generalized to the
  population meeting eligibility criteria
NHBS Website
 Visit www.PreventHIVFlorida.org
 Site has links to publications, presentations,
  and fact sheets on findings
   Local and national
   Categorized by population (MSM, IDU, HET)
   Special Reports – e.g., “Out in the Open”
Credits
 NHBS-HET Miami Other acknowledgements:
Interviewing Team: Miami-Dade County
                      Health Department

Emelina Martinez,
                      Miami Regional
  Roxana Bell,        Laboratory, Florida
 Cristobal Plaza,    Department of Health
  Cheryl Riles,
 Richard Walker     NHBS-HET1 and HET2
                         participants
Contact

       David W. Forrest, Ph.D.
University of Miami School of Medicine
      dforrest@med.miami.edu

High HIV Seropositivity among Heterosexuals at Risk in Miami Confirmed by Two Different Sampling Methods

  • 1.
    High HIV Seropositivityamong Heterosexuals at Risk in Miami Confirmed by Two Different Sampling Methods David W. Forrest, Gabriel A. Cardenas, Marlene LaLota, Dano W. Beck, Lisa R. Metsch, Xierong Wei, Jeffrey A. Johnson, S. Michele Owen, Thomas M. Liberti National HIV Prevention Conference 2011 Atlanta, GA August 15, 2011
  • 2.
    National HIV BehavioralSurveillance (NHBS)  NHBS is a repeated, cross- sectional study of high-risk populations in US MSAs  Target population rotates each year  MSM  IDU  Heterosexuals at increased risk of HIV infection  First round (2004-2007) conducted in Miami- Dade and Broward counties  Second round (2008-2010) in Miami only
  • 3.
    NHBS Objectives "Effective HIVprevention programs rely primarily on changing behavior; therefore, behavioral data are needed to inform these programs.” [1]  NHBS provides data on trends in: Risk behaviors HIV testing behaviors Use and impact of prevention services HIV prevalence and incidence [1] Lansky A, Abdul-Quader AS, Cribbin M, et al. Developing an HIV behavioral surveillance system for injecting drug users: the National HIV Behavioral Surveillance System. Public Health Reports 2007; 122(suppl 1):48-55.
  • 4.
    Target Population for NHBS-HET • The NHBS-HET1 and HET2 cycles targeted heterosexually active adults in areas with high poverty in Miami-Dade County, Florida.
  • 5.
    NHBS-HET Eligibility Criteria Eligible for study participation  18-50 years of age for HET1, 18-60 years of age for HET2  Resident of Miami-Dade County  Male or Female (not transgender)  First-time participant during cycle  Able to complete interview in English or Spanish
  • 6.
    Assessing Characteristics of PopulationX In ON-going surveillance
  • 7.
  • 8.
    NHBS-HET Samples HET-1 •Data collectedthrough venue-based sampling •March 2007 – October 2007 •Miami total sample N=668 HET HET-2 •Data collected through respondent-driven sampling •July 2010 – November 2010 •Miami total sample N=568 HET
  • 9.
    HET Samples forAnalysis Any NHBS-HET participants reporting injection drug use (IDU) and any male participants reporting sex with another male (MSM) in their lifetimes were excluded from this analysis. N=577 for HET1 N=456 for HET2
  • 10.
    Demographics of HET1& HET2 HET1 HET2 African American 80.59% 77.85% Lower income 70.72% 87.06% (<=$14,999) High school education 79% 78.73% or less No health insurance 59.34% 58.41% No visit to a health care 50.78% 46.49% provider in past 12 months Arrested in the previous 30.16% 22.37% 12 months
  • 11.
    Drug use andsexual risk behaviors of HET1 & HET2 HET1 HET2 Heavy alcohol use 26.9% 34.2% Illicit drug use 47.7% 56.36% Alcohol or drug treatment in 26.52% 33.77% lifetime Depression (CES-D 10 scale) 39.17% 52.19% Unprotected vaginal 83.5% 87.5% and/or anal sex HIV testing during the previous 58.5% 55.2% 12 months
  • 12.
    HIV among HET1& HET2 HET1 HET2 HIV positive (HIV test result) 5.7% 7.7% Previously undiagnosed HIV 42.4% 37% (self reported HIV- or unknown plus HIV+ test result) Previously undiagnosed who 85.71% 76.92% reported unprotected vaginal or anal sex in the past 12 months
  • 13.
    HIV in NHBS-HET1 HIVpositive test results were associated in the HET1 sample with: • Crack use in the past 12 months 14.93% vs 4.52% (p=.001) • Self reported Hepatitis C infection 20% vs 5.5% (p=.051)
  • 14.
    HIV in NHBS-HET2 HIV positive test results were associated in the HET2 sample with: • Female gender 11.6% vs 3.6% (p=.001) • Crack use in the past 12 months 19.35% vs 5.84% (p<=.001) • Self reported Hepatitis C infection 23.53% vs 6.96% (p=.011)
  • 15.
    Recent HIV Infection Resultsof tests for recent HIV infection which exclude 12 month MSM and IDU show that 4.5% of the positives in HET1 and 7.1% in HET2 were infected within the previous 12 months.
  • 16.
    Conclusions Our findings documentthe high rates of heterosexually acquired HIV infection in lower-income communities in Miami using two different sampling strategies and underscore the need to increase and optimize HIV testing and other prevention services.
  • 17.
    Limitations  Data arepredominantly self-reported and subject to recall bias  Data are cross sectional and time order cannot be established  Findings can only be generalized to the population meeting eligibility criteria
  • 18.
    NHBS Website  Visitwww.PreventHIVFlorida.org  Site has links to publications, presentations, and fact sheets on findings  Local and national  Categorized by population (MSM, IDU, HET)  Special Reports – e.g., “Out in the Open”
  • 19.
    Credits NHBS-HET MiamiOther acknowledgements: Interviewing Team: Miami-Dade County Health Department Emelina Martinez, Miami Regional Roxana Bell, Laboratory, Florida Cristobal Plaza, Department of Health Cheryl Riles, Richard Walker NHBS-HET1 and HET2 participants
  • 20.
    Contact David W. Forrest, Ph.D. University of Miami School of Medicine dforrest@med.miami.edu