This document provides an introduction and overview of the Ansoft HFSS simulation software. It discusses what HFSS is used for, how to install it, how to get help, and defines key terms related to using the HFSS interface and building models. Specifically, it explains that HFSS is an electromagnetic field simulation software that uses finite element analysis. It also reviews the main sections of the interface like the project manager, property window, and 3D modeler window.
In this chapter we examine the capacity of a single-user wireless channel where transmitter and/or receiver have a single antenna. We will discuss capacity for channels that are both time invariant and time varying. We first look at the well-known formula for capacity of a time-invariant additive white Gaussian noise (AWGN) channel and then consider capacity of time-varying flat fading channels. We will first consider flat fading channel capacity where only the fading distribution is known at the transmitter and receiver. We will also treat capacity of frequency-selective fading channels. For time -invariant frequency-selective channels the capacity is known and is achieved with an optimal power allocation that water-fills over frequency instead of time. We will consider only discrete-time systems in this chapter.
By completing this presentation will be have a clear idea about Antenna's working principles, Antenna's Types & Antenna's Parameters. At the end to this document you'll have a brief idea about Antenna's Tilt vs Distance Calculation & Cluster wise optimum Antenna Selection procedure. Impact of antenna PIM & VSWR have been described elaborately in this document as well.
In this chapter we examine the capacity of a single-user wireless channel where transmitter and/or receiver have a single antenna. We will discuss capacity for channels that are both time invariant and time varying. We first look at the well-known formula for capacity of a time-invariant additive white Gaussian noise (AWGN) channel and then consider capacity of time-varying flat fading channels. We will first consider flat fading channel capacity where only the fading distribution is known at the transmitter and receiver. We will also treat capacity of frequency-selective fading channels. For time -invariant frequency-selective channels the capacity is known and is achieved with an optimal power allocation that water-fills over frequency instead of time. We will consider only discrete-time systems in this chapter.
By completing this presentation will be have a clear idea about Antenna's working principles, Antenna's Types & Antenna's Parameters. At the end to this document you'll have a brief idea about Antenna's Tilt vs Distance Calculation & Cluster wise optimum Antenna Selection procedure. Impact of antenna PIM & VSWR have been described elaborately in this document as well.
In radio and electronics, an antenna is an electrical device which converts electric power into radio waves, and vice versa. It is usually used with a radio transmitter or radio receiver. In transmission, a radio transmitter supplies an electric current oscillating at radio frequency to the antenna's terminals, and the antenna radiates the energy from the current as electromagnetic waves (radio waves). In reception, an antenna intercepts some of the power of an electromagnetic wave in order to produce a tiny voltage at its terminals, that is applied to a receiver to be amplified.
In communication system, intersymbol interference (ISI) is a form of distortion of a signal in which one symbol interferes with subsequent symbols. This is an unwanted phenomenon as the previous symbols have similar effect as noise, thus making the communication less reliable.
In communication system, the Nyquist ISI criterion describes the conditions which when satisfied by a communication channel (including responses of transmit and receive filters), result in no intersymbol interference(ISI). It provides a method for constructing band-limited functions to overcome the effects of intersymbol interference.
Broadside Array vs end-fire array
Higher directivity.
Provide increased directivity in
elevation and azimuth planes.
Generally used for reception.
Impedance match difficulty in
high power transmissions.
Variants are:
Horizontal Array of Dipoles
RCA Fishborne Antenna
Series Phase Array
A horn antenna or microwave horn is an antenna that consists of a flaring metal waveguide shaped like a horn to direct radio waves in a beam. Horns are widely used as antennas at UHF and microwave frequencies, above 300 MHz.
An Antenna is a transducer, which converts electrical power into electromagnetic waves and vice versa.
An Antenna can be used either as a transmitting antenna or a receiving antenna.
A transmitting antenna is one, which converts electrical signals into electromagnetic waves and radiates them.
A receiving antenna is one, which converts electromagnetic waves from the received beam into electrical signals.
In two-way communication, the same antenna can be used for both transmission and reception.
Basic Parameters
Frequency
Wavelength
Impedance matching
VSWR & reflected power
Bandwidth
Percentage bandwidth
Radiation intensity.
InvenSense Developers Conference 2016 -
The Iot market expansion is calling for more flexibility. In this session, you can learn how SensorStudio will help you tackle the challenges ahead. Market trend, SensorStudio solution, and roadmap will be introduced
https://www.invensense.com/sensorstudio/
https://www.invensense.com/products/genericsensorhub-development-kit/
https://www.invensense.com/products/firefly-development-kit/
In radio and electronics, an antenna is an electrical device which converts electric power into radio waves, and vice versa. It is usually used with a radio transmitter or radio receiver. In transmission, a radio transmitter supplies an electric current oscillating at radio frequency to the antenna's terminals, and the antenna radiates the energy from the current as electromagnetic waves (radio waves). In reception, an antenna intercepts some of the power of an electromagnetic wave in order to produce a tiny voltage at its terminals, that is applied to a receiver to be amplified.
In communication system, intersymbol interference (ISI) is a form of distortion of a signal in which one symbol interferes with subsequent symbols. This is an unwanted phenomenon as the previous symbols have similar effect as noise, thus making the communication less reliable.
In communication system, the Nyquist ISI criterion describes the conditions which when satisfied by a communication channel (including responses of transmit and receive filters), result in no intersymbol interference(ISI). It provides a method for constructing band-limited functions to overcome the effects of intersymbol interference.
Broadside Array vs end-fire array
Higher directivity.
Provide increased directivity in
elevation and azimuth planes.
Generally used for reception.
Impedance match difficulty in
high power transmissions.
Variants are:
Horizontal Array of Dipoles
RCA Fishborne Antenna
Series Phase Array
A horn antenna or microwave horn is an antenna that consists of a flaring metal waveguide shaped like a horn to direct radio waves in a beam. Horns are widely used as antennas at UHF and microwave frequencies, above 300 MHz.
An Antenna is a transducer, which converts electrical power into electromagnetic waves and vice versa.
An Antenna can be used either as a transmitting antenna or a receiving antenna.
A transmitting antenna is one, which converts electrical signals into electromagnetic waves and radiates them.
A receiving antenna is one, which converts electromagnetic waves from the received beam into electrical signals.
In two-way communication, the same antenna can be used for both transmission and reception.
Basic Parameters
Frequency
Wavelength
Impedance matching
VSWR & reflected power
Bandwidth
Percentage bandwidth
Radiation intensity.
InvenSense Developers Conference 2016 -
The Iot market expansion is calling for more flexibility. In this session, you can learn how SensorStudio will help you tackle the challenges ahead. Market trend, SensorStudio solution, and roadmap will be introduced
https://www.invensense.com/sensorstudio/
https://www.invensense.com/products/genericsensorhub-development-kit/
https://www.invensense.com/products/firefly-development-kit/
Orchestral and Ethnic Virtual Percussion VST: Syntheway Percussion Kit is a collection of percussion instruments designed for creating Orchestral Percussion, Auxiliary Percussion, Latin Percussion, Indian Percussion, Afro-Cuban Latin Percussion, Afro-Caribbean Latin Percussion, Brazilian and African Percussion, Mallet Percussion: Vibraphone VST, Xylophone VST, Glockenspiel VST, Marimba VST, Tubular Bells VST, Djembe. Also available for Mac as AU (Audio Unit), VST format, Kontakt NKI Sample Library, EXS24 for Logic
Install and config steps on the server side of Cognos Analytics 11. View the webinar video recording and download this deck: http://www.senturus.com/resources/installing-cognos-analytics-v11/.
Topics covered include: new installation options, new configuration options, gateway, changes to server side file locations, a new fix pack methodology. Our Cognos installation and upgrade expert, Todd Schuman, describes the installation and configuration steps on the server side of CA11. Among the highlights: 1) New installation options, 2) New configuration options, 3) Optional Gateway (not really optional), 4) Changes to server side file locations and 5) New fix pack methodology.
Senturus, a business analytics consulting firm, has a resource library with hundreds of free recorded webinars, trainings, demos and unbiased product reviews. Take a look and share them with your colleagues and friends: http://www.senturus.com/resources/.
InvenSense ICS-43432 Digital MEMS Microphone teardown reverse costing report...Yole Developpement
Following the acquisition of MEMS Microphone Business Line of Analog Devices for 100M$ in October 2013, InvenSense releases a high performance digital MEMS Microphone for consumer applications.
The ICS-43432 is a digital microphone equipped with MEMS and amplification ASIC into a single chip. It is designed using CMOS process, it has I2S protocol interface and a high SNR of 65 dBA. It is assembled in a 6-pins LGA 4.0 x 3.0 x 1.0mm package with bottom port.
The MEMS transducer is a condenser microphone with a flexible poly-Si membrane and a rigid reference electrode manufactured on SOI substrate. Compared with state of the art MEMS Microphones, it presents a new design of the diaphragm with octagonal shape and central fixation.
The reverse costing report contains a detailed analysis of the device design and process, its manufacturing cost, as well as a benchmark with competitors’ MEMS microphones.
A brief introduction to Simplified Technical English implementationShumin Chen
ASD-STE100 overview and useful tips to getting started.
ASD-STE100 improves quality, both in the aviation and defence industries, where it is often mandatory for safety reasons, and in any other technical industries.
Simplified Technical English stresses on the use of unambiguous terminology where one word only has one meaning. This reduces the likelihood of using synonymous terms that can result in confusion. Optimum re-usability of technical terms on the word, phrase, and sentence levels is to be expected. This will greatly improve any product life-cycle management process.
To conclude, technical documentation becomes easier for non-native speakers of the English language to understand. The resulting text is much easier to translate which is especially relevant when machine translation is part of your localisation strategy. Preparing your technical content with ASD-STE100 ensures quality at the source and prepares you for future-proof translation processes.
Its Finally Here! Building Complex Streaming Analytics Apps in under 10 min w...DataWorks Summit
Imagine if you could build and deploy an end to end complex streaming analytics app on a streaming engine like Storm or Flink that did the following:
1. Joining Streams
2. Aggregations over Windows (Time or Count based)
3. Complex Event Processing
4. Pattern Matching
5. Model scoring.
Now imagine implementing and deploying this without writing a single line of code in under 10 mins.
Imagine no more; it is indeed here. In this talk, we will discuss an exciting open source project led by Hortonworks on building and deploying streaming applications using a drag and drop paradigm.
Upgrading to Cognos Analytics Release 4: What You Need to KnowSenturus
Installation, configuration and architectural considerations you need to know when upgrading to Cognos Analytics release 4. View the webinar video recording and download this deck at: http://www.senturus.com/resources/what-you-need-to-know-before-upgrading-to-cognos-analytics/.
Topics covered describe what has changed since the last release: 1) Updated prerequisites, 2) New installation options, 3) Changes to the configuration, 4) Changes to the gateway, 5) Latest news on legacy studios and 6) Odds and ends.
Senturus, a business analytics consulting firm, has a resource library with hundreds of free recorded webinars, trainings, demos and unbiased product reviews. Take a look and share them with your colleagues and friends: http://www.senturus.com/resources/.
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FPL'2014 - FlexTiles Workshop - 1 - FlexTiles OverviewFlexTiles Team
Slides presented at the FlexTiles Workshop at FPL'2014.
Presentation #1: FlexTiles overview
FlexTiles is a heterogeneous many-core platform reconfigurable at run-time developed within an FP7 project.
Slides for the presentation I did remotely at Open Source World, to talk about audio-only WebRTC applications, and what we've done in Janus to improve and cover the requirements so far.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.