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Glaucoma
Progression Analysis
Dr Shylesh Dabke
Glaucoma Consultant,
Aravind Eye Hospital, TVL
▰ In managing glaucoma, the doctor’s primary goal is minimizing the risk of visual disability
during the lifetime of the patient.
▰ Achieving this goal requires a comprehensive strategy
Staging
Life
expectancy
Disease
progression
Visual
fields
ONHRNFL
Staging
Life
expectancy
Disease
progression
Visual
fields
ONHRNFL
Disease
progression
Event-based
analysis
Trend-based
analysis
Change
from baseline
Rate of change*
Historically, estimating rate of progression,
has been more difficult.
o Rate of progression is highly individual among
patients, and not all patients progress at vision-
threatening rates.
o It is difficult to differentiate true progression from
variations in patient physiology and test performance
and clinician interpretation.
“A Welcome Technological Advance
▰Software available for both structural and functional
testing that can provide clinicians with the relevant
quantitative and statistical analysis to objectively
measure progression
Glaucoma
Progression
Analysis(GPA)
Guided Progression Analysis™ (GPA™)
ZEISS
Instruments
 Measure rates of disease progression across both structure and function -
Crucial for optimal management of glaucoma patients.
Safeguarding Patients’ Vision
▰ Latest glaucoma progression analysis tools help physicians to meet one
of the most important challenges in treating patients with glaucoma
- Detect patients whose disease is worsening rapidly.
▰ It is important to identify them because they can benefit from more
frequent examination or more aggressive therapy.
GPA
Event Analysis
Trend Analysis*
Assessments
5 - HFA
4 - OCT
GPA
Event Analysis
Trend Analysis*
Assessments
5 - HFA
4 - OCT
Assessments
5 - HFA
4 - OCT
3 – Event Analysis
+2 – likelihood/rate
of progression
2 Baseline Scans
13
14
16
17
“FORUM®
While these new tools should never replace the clinical
judgment of the physician, the improved understanding
of the rate of disease progression they offer provides
the best chance of minimizing visual disability for our
patients
To Conclude….
The End!!!!

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Glaucoma Guided Progression Analysis - Dr Shylesh Dabke

Editor's Notes

  1. Areas of change are color-coded yellow when first noted and then red when the change is sustained over consecutive visits.
  2. Orange marker denotes change when it is first noted. Maroon marker denotes change sustained over consecutive visits. Rate of change is shown in text.
  3. Areas of statistically significant change are color coded orange when first noted and maroon when the change is sustained over consecutive visits.
  4. Summarizes Guided Progression Analysis (GPA) analyses and indicates with a check mark if there is possible or likely loss of RNFL.
  5. A graphical estimate of the patient’s remaining useful vision at the current VFI value along with a 2- to 5-year projection of the VFI regression line if the current trend continues.
  6. A graphical estimate of the patient’s remaining useful vision at the current VFI value along with a 2- to 5-year projection of the VFI regression line if the current trend continues.