13. Galactosemia, Chemicals Connections
Accumulation of GALACTITOL
within the lens cells leads to
increased intracellular osmotic
pressure and fluid influx into the
lens and in the brain.
The deficiency of formation of
UDP-Glucose interferes with
the storage of glucose in the
form of glycogen, in the
formation of UDP-Glucoronic
acid for the conjugation of
bilirubin and the accumulation
of galactose in the liver and
kidney