This document discusses fostering research for policy and practitioners through cohort and longitudinal studies. It provides an overview of CIFF's mission and strategic priority areas. CIFF seeks transformational impact through a systematic approach across sectors like education, nutrition, health, and climate change. CIFF currently has a portfolio of 57 investments totaling $560 million spread across innovation, pilot programs, delivery at scale, and systems change. The document discusses challenges in achieving scale and uptake of research findings, and how CIFF is approaching these challenges through clear theories of change, cost evaluations, communication of evidence, and partnerships.