Flaps are vascularized blocks of tissue that are mobilized from a donor site and transferred to another location for reconstructive purposes. They can carry skin, muscle, bone or other tissues. Classification is based on congruity, circulation, and anatomical components. Key principles include replacing like with like tissue and ensuring an adequate blood supply from the pedicle or microvascular anastomosis. Complications can include congestion, infection or partial/complete flap loss if the blood supply is compromised.
A flap is a unit of tissue that is transferred from one site (donor site) to another (recipient site) while maintaining its own blood supply or from a anastomised vessel.
Flaps come in many different shapes and forms. They range from simple advancements of skin to composites of many different types of tissue
A flap is a unit of tissue that is transferred from one site (donor site) to another (recipient site) while maintaining its own blood supply or from a anastomised vessel.
Flaps come in many different shapes and forms. They range from simple advancements of skin to composites of many different types of tissue
Flap coverage in upper extremities in trauma VishalPatil483
SEMINAR PRESENTED BY DR VISHAL PATIL ,IN THE DEPT OF TRAUMA SURGERY AND CRITICAL CARE, AIIMS RISHIKESH
INCLUDES-INTRODUCTION-CLASSIFICATIONS OF FLAP-COMPLICATIONS RELATED TO FLAP COVERAGE- FLAP USED IN HAND AND UPPER EXTREMITY SOFT TISSUE RECONSTRUCTION WITH PICTURES OF IT
Local & regional flaps /certified fixed orthodontic courses by Indian dental ...Indian dental academy
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A power point on the various types of flaps and their respective indications. This presentation briefly describes the various flaps and how to care for flaps.
FLAPS IN ORAL AND MAXILLOFACIAL SURGERY (monday ppt).pptxaasthamoza
Method and type of flaps used for head and neck reconstruction. Comprising of local regional and free flaps. Indications and pitfalls in each type of flap .
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
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- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
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Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
2. Contents
• Introduction
• History
• pathophysiology
• Graft vs flap
• Classifications of flaps
• Principles of flap surgery
• Post operative assessment of
flap
• complications
3. • A flap is a vascularized block of tissue that
is mobilized from its donor site and
transferred to another location, adjacent or
remote, for reconstructive purposes.
4. • A flap is used :
• To reconstruct a large primary defect
• Replace tissue loss during trauma or
surgical excision.
• Provide padding over bony
prominences.
• Bring in better blood supply to
poorly vascularizedbed.
• Improve sensation to an area{sensate
flap}
5. • Bring in specialized tissue for reconstruction
such as bone or functioning muscle.
6. History
• Origin in india:In 600
BC, Sushruta Samita
described operations
for nasal
reconstruction—,
since amputation of
the nose (an organ
of "respect and
reputation") was
common as criminal
punishment.
• He used cheek flap
for reconstruction of
nose.
7. History cont..
• the first muscle flap
of recorded history
debuted in 1906.
• Louis Ombredanne
of Paris described
the use of the
pectoralis minor
muscle for breast
reconstruction
following
mastectomy.
8. History cont..
• Sir Harold Delf
Gillies:
• considered the
father of plastic
surgery.
• Pioneer in facial
injury repairs.
9. Differences between flap
and graft:
graft flap
Limited to transplantation of skin Can carry other tissues
Depends on recipient site on nutrion Has its own blood supply
Cosmetic –may discolor or contract Better color take and less likely
to contract
Less adaptable to weight bearing Most adaptable to weight bearing
Less able to survive on a bed with
questionable nutrition
Can be used on a bed with
questionable
nutrition
Requires pressure dressing Does not requires pressure dressing
Cannot bridge defects Can bridge defects
10. Physiologic factors affecting
flap survival:
• includes-
• 1.blood supply to the flap through its base.
• 2.formation of new vascular channels between
flap and recipient bed.
• 3.perfusion pressure of the supplying blood
vessel.
11. pathophysiology
chronologic changes of a flap and the recipient site
after elevation and transfer:
• After 10-24 hours - Decreased arterial supply;
congestion and edema; dilation of arterioles
and capillaries
• After 1-3 days - Increased number and quality of
anastomoses between flap and recipient bed;
increased number of small vessels in pedicle
• After 3-7 days - Reorientation of vessels along the
long
axis of the flap; anastomoses created at 1-3 days
now functionally significant
• After 1 week - Circulation well established between
flap and recipient bed
• After 2 weeks - Continuous maturation of
anastomoses
13. Classification of flapscont..
Based on congruity:
A. local flap:
• A local flap implies
that the tissue is
adjacent to the open
wound in need of
coverage.
• Eg. A wound on lip
may be repaired by a
flap on adjacent
cheek
14. Classification: Basedon
congruity:cont..
• B. Regional flap:
• Skin flap is not from the adjacent area but from
the same region
• Eg.wound on the tip of the nose might be
repaired with a flap from forehead.
• C. Distant flap:
• Tissue transferred from an non contiguous
anatomic site (ie, from a different part of the
body) is referred to as a distant flap.
15. Classification: Based on
congruity:cont..
• Distant flap Is of two types:
1.pedicled flap:is transferred while flap is
still attached to their original blood supply.
2.Free flap:Free flaps are physically detached
from their native blood supply and then
reattached to vessels at the recipient site.
This anastomosis typically is performed
using a microscope, thus is known as a
microsurgical anastomosis.
17. Classification: Based oncirculation
• A. Axial pattern
flap:
• An axial pattern
flap contains
atleast one direct
cutaneous branch
blood supply
along its
longitudinal axsis.
19. Classification: On the basisof
anatomical content:
1.Skin flap
2.Muscle and myocutaneous
flap 3.Fascia and fascio
cutaneous flap
20. Skin flap:
• Uses:
• 1.recipent bed with poor vascularity
• 2.coverage of vital structures
• 3.reconstructing full thickness structures
e.g.eyelid
,cheek, nose, lip, ear etc.
• 4.padding of bony prominences
21. Skin flaps:cont..
Types :
1.Those rotating around a pivot
point:
• a)rotation flap
• b) transpositionflap
•c)interpolation
flap
2.advancement
flaps
• a)single pedicled advancement
flap
22. Skin flaps:cont..
A.Rotation flaps :
are semicircular flaps of skin and
subcutaneoustissue
• that revolve in an arc around a pivot point to
shift tissue in a circle.
• Rotation flaps provide the ability to mobilize
large areas of tissue with a wide vascular
base for reconstruction
25. Skin flaps:cont..
• C. interpolation flap:
is from a near by
but not immediately
adjacent donor site
and transposed
either above or
below the
intervening skin to
recipient defect.
26. Skin flaps:cont..
Advancement flap:
• Advancement flaps move directly forward and
rely on skin elasticity to stretch and to fill a
defect.
• No rotational or lateral movement is applied
• It is of 3 types:
A.single pedicle advancement
flap. B.bipedicle advancement
flap.
C.v-y flap advancement flap.
27. Skin flaps:advancement flapcont..
• Single pedicle advancement flap: Here the
rectangular skinflap is moved forward by virtue
of its elastic properties.
• Bipedicle flap: here an insicion is made
parallel to the defect and the flap is
undermined and advanced
28. Skin flaps:advancement flapcont..
V-Y advancement flap:
V-Y advancement flaps advance skin on each
side of a V-shaped incision to close the wound
with a Y- shaped closure.
• The V-Y pedicle plasty technique allows
most patients to regain sensation and
two-point discrimination in the fingertip
29.
30. Skin flap: typescont..
Rhomboid flaps:( limberg flap.)
• rely on the looseness of adjacent skin to
transfer
• a rhomboid-shaped flap into a defect that has
been converted into a similar rhomboid shape
31. Skin flap: typescont..
• Z-plasty:
• Z-plasty transposes two interdigitating
triangular flaps without tension to use lateral
skin to produce a gain in length along the
direction of the common limb of the Z.
32. Skin flap: typescont..
Common indications of z plasty:
• lengthening of a contracted linear scar
across a flexor crease.
• changing the direction of a
cosmetically unfavorable scars.
33. Muscle and myocutaneousflap:
• Consideration of a muscle as a potential
flap is possible because muscles have
independent, intrinsic blood supply.
• Compared with skin flaps, muscle flaps are
less stiff,and more malleable to conform to
wounds with irregular three dimensional
contours.
• Muscle flaps are classified according to their
principal means of blood supply and the
patterns of vascular anatomy and according to
mode of innervation.
34.
35. Common muscleflaps:
Tensor Fascia Lata:
• Applications- Coverage of lower abdominal
wall, perineum, ischium and sacrum
• Vascular Anatomy: Ascending branch
lateral circumflex femoral (off Profunda
femoris)
36. Common muscleflaps:
Trapezius:
• Applications – Skull,
head and neck, Oral
cavity, posterior trunk
and shoulder.
Mandible facial
reanimation.
• blood supply:
Dominant: Transverse
cervical artery Length
. Minor: Branch of
Occipital artery. Dorsal
Scapular artery.
37. Common muscleflaps:
Gluteus Maximus:
• Applications –
Sacrum , Ischium,
Trochanter, breast
reconstruction
• Vascular Anatomy
:Dominant: Superior
gluteal artery Inferior
Gluteal artery ,Minor:
First perforator of
Profunda femoris ,
Intermuscular
branches of lateral
circumflex femoral
artery.
38. Common muscleflaps:
Pectoralis Major
myocutaneous
flap:
• Applications: Coverage,
Reconstruction,
Functional transfer,
Free flap.
• Vascular Anatomy:
Dominant: Pectoral
branch of
Thoracoacromial
artery.Minor :Pectoral
branch of lateral thoracic
, Minor Segmental
Internal mammary
39. Common muscleflaps:
Transverse rectus
abdominis muscle flap
(TRAM flap):
• It is either superior
pedicle based on the
superior epigastric
vessels or inferior pedicle
based on the inferior
epigastric.
• Superior pedicle based
flap is used to cover
postmastectomy area or
chest wall defect.
• Inferior pedicle flap is used
40. Common muscleflaps:
Serratus Anterior :
Applications – head and neck, Thorax, axilla,
posterior trunk, breast reconstruction and free
tissue transfer.
Vascular anatomy: Dominant Lateral
thoracic Branches of Thoracodorsal
artery.
41. Myocutaneous flap:
• A musculocutaneous flap, also called a
myocutaneous flap, is a muscle flap designed
with an attached skin paddle.
42. Fascia and FasciocutaneousFlaps:
• Fasciocutaneous flaps are tissue flaps that
include skin, subcutaneous tissue and the
underlying fascia.
• They can be raised without skin and are
then referred to as fascial flaps.
• fasciocutaneous flaps to provide coverage
when a skin graft or random skin flap is
insufficient for coverage (eg, in coverage
over tendon or bones).
43. Fascia and FasciocutaneousFlaps:
cont..
• Because they are less bulky, fasciocutaneous
flaps are indicated when thinner flaps are
required
• Fasciocutaneous flaps are not as resistant
to infection as muscle flaps. Monitoring flap
failure occasionally can be difficult
45. Principles of flapsurgery
Principle I: Replace Like With Like
when a part of one's person is lost, it should be
replaced in kind, bone for bone, muscle for
muscle, hairless skin for hairless skin, an eye
for an eye, a tooth for a tooth
46. Principles of flap surgerycont..
• Principle II: Think of Reconstruction in
Terms of Units
• human beings may be divided into 7 main
parts: the head, neck, body, and extremities.
Each of these body parts can be further
subdivided into units.
• The head, for example, is composed of
several regional units: scalp, face, and
ears. All of these different units and
subunits must be considered and
reproduced during reconstruction.
47. Principles of flap surgerycont..
principle III: Always Have a Pattern and a
Back-up Plan
• the surgeon should ask him or herself "what do
I do next if this fails?" Proceed to the operating
room only after answering this question
definitively
• Principle IV: Never Forget the Donor Area:
48. Postoperative flapmonitoring:
• The gold standard of postoperative flap
monitoring is clinical observation.It includes:
• 1.flap color
• 2.capillary refilling time
• 3.surface temperature monitoring
• 4.Blanching assesment
50. Causes of flapfailure:
• poor anatomical knowledge when raising
the flap(such that the blood supply is
deficient from the start)
• flap inset with too much tension.
• local sepsis or a septicaemic patient.
• the dressing applied too tightly around the
pedicle.