Fetal biometry parameters are ultrasound measurements used to indirectly assess fetal growth and well-being, including biparietal diameter, head circumference, abdominal circumference, and femoral length. These measurements are used in formulas to estimate gestational age and fetal weight. Intrauterine growth restriction is defined as a birth weight below the 10th percentile for gestational age and can be symmetrical, affecting overall growth, or asymmetrical, primarily impacting abdominal growth. Ultrasound biometry, particularly abdominal circumference, allows accurate prenatal diagnosis of growth issues.
In this presentation we will discuss
First trimester US especially TVS is an integral part for confirmation of intrauterine pregnancy and to rule out ectopic pregnancy.
First trimester US helps us in suggesting conceptus viability.
First trimester US especially TVS is very efficient in approaching and evaluating the cause of vaginal bleeding.
Obstetric ultrasonography, or prenatal ultrasound, is the use of medical ultrasonography in pregnancy, in which sound waves are used to create real-time visual images of the developing embryo or fetus in the uterus.
ultrasonography in obstetrics, usg in obstetrics, ultrasound in obstetrics, doppler in obstetrics, usg doppler in obstetrics, signs in ultrasound, anomaly scan, pregnancy scan, ultrasound in pregnancy,
Nuchal translucency
It is a sonographic pre natal screening scan to detect cardiovascular abnormality in a fetus.
NT can also detect altered extra cellular matrix composition and limited lymphatic drainage
In this presentation we will discuss
First trimester US especially TVS is an integral part for confirmation of intrauterine pregnancy and to rule out ectopic pregnancy.
First trimester US helps us in suggesting conceptus viability.
First trimester US especially TVS is very efficient in approaching and evaluating the cause of vaginal bleeding.
Obstetric ultrasonography, or prenatal ultrasound, is the use of medical ultrasonography in pregnancy, in which sound waves are used to create real-time visual images of the developing embryo or fetus in the uterus.
ultrasonography in obstetrics, usg in obstetrics, ultrasound in obstetrics, doppler in obstetrics, usg doppler in obstetrics, signs in ultrasound, anomaly scan, pregnancy scan, ultrasound in pregnancy,
Nuchal translucency
It is a sonographic pre natal screening scan to detect cardiovascular abnormality in a fetus.
NT can also detect altered extra cellular matrix composition and limited lymphatic drainage
Poor neonatal acid–base status in term fetuses with low cerebroplacental ratio
J. Morales-Roselló, A. Khalil, M. Morlando, A. Bhide, A. Papageorghiou and B. Thilaganathan
Volume 45, Issue 2, Date: February (pages 156–161)
http://onlinelibrary.wiley.com/doi/10.1002/uog.14647/abstract
Human fetal growth is constrained below optimal for perinatal survival
B. Vasak, S.V. Koenen, M.P.H. Koster, C.W.P.M. Hukkelhoven, A. Franx, M.A. Hanson and G.H.A. Visser
Volume 45, Issue 2, Date: February (pages 162–167)
http://onlinelibrary.wiley.com/doi/10.1002/uog.14644/abstract
The UOG Journal Club for March 2014 features two papers, the first of which is a risk assessment of SGA fetuses using 31-34 week biometry, whilst the second investigates whether changes in Doppler indices can act as markers of a failure to reach growth potential at term.
Optimal risk assessment of small-for-gestational-age fetuses using 31–34-week biometry in a low-risk population
J. J. Stirnemann, G. Benoist, L. J. Salomon, J.-P. Bernard and Y. Ville
Volume 43, Issue 3, Date: March 2014, pages 311-316
http://onlinelibrary.wiley.com/doi/10.1002/uog.13288/abstract
Changes in fetal Doppler indices as a marker of failure to reach growth potential at term
J. Morales-Roselló, A. Khalil, M. Morlando, A. Papageorghiou, A. Bhide and B. Thilaganathan
Volume 43, Issue 3, Date: March 2014, pages 303-310
http://onlinelibrary.wiley.com/doi/10.1002/uog.13319/abstract
Maternal Care: Assessment of fetal growth and condition during pregnancySaide OER Africa
Maternal Care addresses all the common and important problems that occur during pregnancy, labour, delivery and the puerperium. It covers: the antenatal and postnatal care of healthy women with normal pregnancies, monitoring and managing the progress of labour, specific medical problems during pregnancy, labour and the puerperium, family planning, regionalised perinatal care
Raynaud's disease, also known as Raynaud's phenomenon or Raynaud's syndrome, is a condition that affects blood flow to certain parts of the body—usually the fingers and toes. In Raynaud's disease, smaller arteries that supply blood to the skin constrict excessively in response to cold or stress, limiting blood supply to affected areas (vasospasm). This can lead to numbness, tingling, and color changes in the affected areas, typically turning them white or blue.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
In India, pharmacovigilance activities are monitored by the Pharmacovigilance Programme of India (PvPI), which works closely with CDSCO to collect, analyze, and act upon data regarding adverse drug reactions (ADRs). Together, they play a critical role in ensuring that the benefits of drugs outweigh their risks, maintaining high standards of patient safety, and promoting the rational use of medicines.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
3. Stepwise Approach
1. Fetal lie and presentation
2. Fetal cardiac activity
3. Number of fetuses in the uterus
4. Adequacy of amniotic fluid
5. Localization of the placenta
6. Fetal biometry
10. Fetal biometry
Fetal biometric parameters are antenatal
ultrasound measurements that are used to
indirectly assess the growth and well being
of the fetus.
12. Biparietal diameter
• The BPD is the maximum diameter of a transverse
section of the fetal skull at the level of the parietal
eminences.
• Measured from the outer edge of the proximal skull to
the inner edge of the distal skull at the level of thalami &
cavum septum pellucidum.
• Easy to obtain.
• More accurate than CRL .
• More accurate in predicting EDD than LMP.
22. Abdominal Circumference
• The single most important measurement to make in late pregnancy. It reflects more of fetal size and weight
rather than age. Serial measurements are useful in monitoring growth of the fetus.
37. Assigning GA in second and third trimester
• In the second and third trimesters, gestational age can be assigned
based on a single measurement, such as the BPD,corrected BPD,HC,
or FL.
• Head measurements that take into account the shape of the fetal head
namely, the corrected BPD and the HC are more accurate than the BPD
alone or FL alone in the second trimester.
• Accuracy of the corrected BPD and the HC before 20 weeks is
approximately ±1.2 weeks.
38. • By the end of the third trimester, the accuracy of gestational age
estimation by head measurements is about ±3.5 weeks
• The accuracy of the FL is similar to that of head
measurements by third trimester.
• The AC is a poor predictor of gestational age, particularly later in
pregnancy, and should not be used on its own to assign gestational
age
39. • Composite age formulas estimate gestational age via two or more
fetal measurements such as the BPD, HC, FL, and AC ,the accuracy of gestational
age estimation using these composite age formulas is similar to the
accuracy of the corrected BPD and HC and is more accurate than age estimation
using the FL.
• One drawback is the potential to miss an abnormal measurement or anomaly, for
example,if the fetal head is abnormally small and the FL and AC are normal for
gestational age, the composite age formula that incorporates measurements of
the BPD,HC,FL,and AC will be an underestimation of the true age.
40.
41.
42.
43. • Formulas that use measurements of the fetal head, abdomen, and
femur have a mean error of 15% (±2 standard deviations [SDs]).
• Formulas that use fewer than three measurements of fetal body
parts perform less well(i.e.,have larger standard deviations).
• Adding other measurements to the head, abdomen, and femur, such
as the thigh circumference or thickness of thigh soft tissue or
three-dimensional volume calculations, does not improve accuracy of weight estimation.
• Despite considerable improvements in sonographic equipment, the
accuracy of estimating fetal weight has not changed since the development of formulas 3 decades
ago.
44.
45. The fetal biometry necessary for measuring the fetal weight was as follows:
• Sheppard (BPD, AC),
• Campbell (AC),
• Hadlockl-I(AC, FL),
• Hadlock II (BPD, AC, FL),
• Hadlock III (HC, AC, FLx HC),
• Hadlock IV (BPD, HC, AC, FL)}
46.
47. IUGR
• The “normal” neonate is one whose birth weight is between the 10th
and 90th percentile as per the gestational age, gender and race with
no feature of malnutrition and growth retardation.
• IUGR is a pathology involving reduced fetal growth potential of a
specific infant as per the race and gender of the fetus
48. Definition:
• Most commonly defined as a birth weight below the 10th percentile
considering gender and gestational age; a birth weight lower than
2500 grams in a pregnancy of 37 weeks or more; the birth weight is
more than 2 SD below the average mean.
49. Types:
Two different types of IUGR:
Symmetrical(primary):
• Symmetric IUGR is characterized by all internal organs being reduced in
size.
• indicates that the fetus has developed slowly throughout the duration of
the pregnancy and was thus affected from a very early stage
• 20–30% of all cases of IUGR
• Causes: early intrauterine infections cytomegalovirus, rubella or
toxoplasmosis, chromosomal abnormalities,, anemia and maternal
substance abuse
50. Asymmetric (secondary):
• characterized by the head and brain being normal in size, but the
abdomen is smaller
• accounts for 70–80% of all cases of IUGR
• this is not evident until the third trimester.
• The most common causes are placental insufficiency and pre-
eclampsia.
51. Small for gestational age (SGA):
• SGA definition has been used for those neonates whose birth weight is less
than the 10th percentile for that particular gestational age or two standard
deviations below the population norms on the growth charts
• This definition considers only the birth weight without any consideration of
the impaired development.
• 70% of the newborns with a birth weight below the 10th percentile are
small in their constitutional factors including maternal height, weight,
ethnicity, and parity, although they are proportionate, healthy, well
developed and well nourished (e.g. born to parents who are small and/or
into an ethnic population that is smaller than the reference population)
52. • Intrauterine fetal weight is usually determined according to the
relevant formulas (most often M. J. Shepard's and F. P. Hadlock's)
which include BPD, HC, FL and AC measurements.
• The parameter classically affected is AC, so the highest diagnostic
accuracy of IUGR is achieved when this dimension is used.
• The sensitivity of the latter examination is as high as 95% if the AC
value during the measurement is below the 2.5th percentile
53. • Thus, ultrasound fetal biometry remains the “golden standard” for
assessing IUGR in case of singleton and multiple pregnancies. The
EFW, for example, has fairly high sensitivity of 89% for FGR,but its
positive predictive value is only 45%.
• Supplementary ultrasound examination methods, e.g., Doppler test
and measurements of the quantity of amniotic fluid, are helpful in
providing additional information about fetal growth and development
during the prenatal period.
54. References:
• Ultrasound in Obstetrics and gynecology: A Practical Approach
• Fetal biometry: Relevance in obstetrical practice
• Callen's Ultrasonography in Obstetrics and Gynecology