The document discusses various psychological and physiological factors that affect learning. Some key psychological factors include readiness, interest, intelligence, motivation, attitudes, feelings, frustration, aptitude, mental health, natural ability to learn, individual differences, ability, orientation, and fear of failure. Physiological factors discussed include maturity, needs, physical health, self-concept, proper nutrition, proper sleep, and tiredness. The document emphasizes that teachers should understand these factors and how they influence learning in order to best support their students' education.