This document provides an overview of exploratory data analysis (EDA). It discusses how EDA is used to generate and refine questions from data by visualizing, transforming, and modeling the data. Questions can come from hypotheses, problems, or the data itself. EDA plays a role in developing, testing, and refining theories, solving problems, and asking interesting questions about the data. The document emphasizes being skeptical of assumptions and open to multiple interpretations during EDA to maximize learning from the data. It introduces the dplyr and ggplot2 packages for selecting, filtering, summarizing, and visualizing data during the EDA process.
Exploratory data analysis data visualization:
Exploratory Data Analysis (EDA) is an approach/philosophy for data analysis that employs a variety of techniques (mostly graphical) to
Maximize insight into a data set.
Uncover underlying structure.
Extract important variables.
Detect outliers and anomalies.
Test underlying assumptions.
Develop parsimonious models.
Determine optimal factor settings
Data visualization in data science: exploratory EDA, explanatory. Anscobe's quartet, design principles, visual encoding, design engineering and journalism, choosing the right graph, narrative structures, technology and tools.
This presentation gives the idea about Data Preprocessing in the field of Data Mining. Images, examples and other things are adopted from "Data Mining Concepts and Techniques by Jiawei Han, Micheline Kamber and Jian Pei "
Exploratory data analysis data visualization:
Exploratory Data Analysis (EDA) is an approach/philosophy for data analysis that employs a variety of techniques (mostly graphical) to
Maximize insight into a data set.
Uncover underlying structure.
Extract important variables.
Detect outliers and anomalies.
Test underlying assumptions.
Develop parsimonious models.
Determine optimal factor settings
Data visualization in data science: exploratory EDA, explanatory. Anscobe's quartet, design principles, visual encoding, design engineering and journalism, choosing the right graph, narrative structures, technology and tools.
This presentation gives the idea about Data Preprocessing in the field of Data Mining. Images, examples and other things are adopted from "Data Mining Concepts and Techniques by Jiawei Han, Micheline Kamber and Jian Pei "
Data mining Course
Chapter 2: Data preparation and processing
Introduction
Domain Expert
Goal identification and Data Understanding
Data Cleaning
Missing values
Noisy Data
Inconsistent Data
Data Integration
Data Transformation
Data Reduction
Feature Selection
Sampling
Discretization
This presentation briefly explains the following topics:
Why is Data Analytics important?
What is Data Analytics?
Top Data Analytics Tools
How to Become a Data Analyst?
Exploratory data analysis in R - Data Science ClubMartin Bago
Â
How to analyse new dataset in R? What libraries to use, and what commands? How to understand your dataset in few minutes? Read my presentation for Data Science Club by Exponea and find out!
Data preprocessing techniques
See my Paris applied psychology conference paper here
https://www.slideshare.net/jasonrodrigues/paris-conference-on-applied-psychology
or
https://prezi.com/view/KBP8JnekVH9LkLOiKY3w/
BA is used to gain insights that inform business decisions and can be used to automate and optimize business processes. Data-driven companies treat their data as a corporate asset and leverage it for a competitive advantage. Successful business analytics depends on data quality, skilled analysts who understand the technologies and the business, and an organizational commitment to data-driven decision-making.
Business analytics examples
Business analytics techniques break down into two main areas. The first is basic business intelligence. This involves examining historical data to get a sense of how a business department, team or staff member performed over a particular time. This is a mature practice that most enterprises are fairly accomplished at using.
3 pillars of big data : structured data, semi structured data and unstructure...PROWEBSCRAPER
Â
There are 3 pillars of Big Data
1.Structured data
2.Unstructured data
3.Semi structured data
Businesses worldwide construct their empire on these three pillars and capitalize on their limitless potential.
In this presentation, I have talked about Big Data and its importance in brief. I have included the very basics of Data Science and its importance in the present day, through a case study. You can also get an idea about who a data scientist is and what all tasks he performs. A few applications of data science have been illustrated in the end.
Data mining Course
Chapter 2: Data preparation and processing
Introduction
Domain Expert
Goal identification and Data Understanding
Data Cleaning
Missing values
Noisy Data
Inconsistent Data
Data Integration
Data Transformation
Data Reduction
Feature Selection
Sampling
Discretization
This presentation briefly explains the following topics:
Why is Data Analytics important?
What is Data Analytics?
Top Data Analytics Tools
How to Become a Data Analyst?
Exploratory data analysis in R - Data Science ClubMartin Bago
Â
How to analyse new dataset in R? What libraries to use, and what commands? How to understand your dataset in few minutes? Read my presentation for Data Science Club by Exponea and find out!
Data preprocessing techniques
See my Paris applied psychology conference paper here
https://www.slideshare.net/jasonrodrigues/paris-conference-on-applied-psychology
or
https://prezi.com/view/KBP8JnekVH9LkLOiKY3w/
BA is used to gain insights that inform business decisions and can be used to automate and optimize business processes. Data-driven companies treat their data as a corporate asset and leverage it for a competitive advantage. Successful business analytics depends on data quality, skilled analysts who understand the technologies and the business, and an organizational commitment to data-driven decision-making.
Business analytics examples
Business analytics techniques break down into two main areas. The first is basic business intelligence. This involves examining historical data to get a sense of how a business department, team or staff member performed over a particular time. This is a mature practice that most enterprises are fairly accomplished at using.
3 pillars of big data : structured data, semi structured data and unstructure...PROWEBSCRAPER
Â
There are 3 pillars of Big Data
1.Structured data
2.Unstructured data
3.Semi structured data
Businesses worldwide construct their empire on these three pillars and capitalize on their limitless potential.
In this presentation, I have talked about Big Data and its importance in brief. I have included the very basics of Data Science and its importance in the present day, through a case study. You can also get an idea about who a data scientist is and what all tasks he performs. A few applications of data science have been illustrated in the end.
This presents an overview about relevance and significance of statistics as a valid tool in enhancing quality of research. It also touches upon some misuse and abuse of statistics.
Research methods can generally be divided into two main categories: Quantitative and Qualitative. This webinar will provide an overview of quantitative methods with a brief distinction between quantitative and qualitative methods. We will focus on when and how to use quantitative research and discuss type of variables and statistical analysis.
Presentation will be led by Dr. Carlos Cardillo.
About CORE:
The Culture of Research and Education (C.O.R.E.) webinar series is spearheaded by Dr. Bernice B. Rumala, CORE Chair & Program Director of the Ph.D. in Health Sciences program in collaboration with leaders and faculty across all academic programs.
This innovative and wide-ranging series is designed to provide continuing education, skills-building techniques, and tools for academic and professional development. These sessions will provide a unique chance to build your professional development toolkit through presentations, discussions, and workshops with Tridentâs world-class faculty.
For further information about CORE or to present, you may contact Dr. Bernice B. Rumala at Bernice.rumala@trident.edu
Research design decisions and be competent in the process of reliable data co...Stats Statswork
Â
Research Design may be described as the researchers scheme of outlining the flow of his project. It is based on research design, that the researcher goes about gathering data to answer his research question. It enables the researcher to prioritize his work, create better questionnaires and arrive at conclusions with greater clarity. Statswork offers statistical services as per the requirements of the customers. When you Order statistical Services at Statswork, we promise you the following â Always on Time, outstanding customer support, and High-quality Subject Matter Experts.
Learn More: http://bit.ly/2S312hb
Why Statswork?
Plagiarism Free | Unlimited Support | Prompt Turnaround Times | Subject Matter Expertise | Experienced Bio-statisticians & Statisticians | Statistics Across Methodologies | Wide Range Of Tools & Technologies Supports | Tutoring Services | 24/7 Email Support | Recommended by Universities
Contact Us:
Website: www.statswork.com/
Email: info@statswork.com
UnitedKingdom: +44-1143520021
India: +91-4448137070
WhatsApp: +91-8754446690
The Emerging Discipline of Data Science: Principles and Techniques for Data-Intensive Analysis, Keynote, 2nd Swiss Workshop on Data Science â SDS|2015, Winterthur, Switzerland, 12 June 2015
Abstract and other presentations at: http://michaelbrodie.com/?page_id=17
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Â
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.Â
 Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Ioâs surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Ioâs trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Ioâs surface using adaptive
optics at visible wavelengths.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Â
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other  chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released. Â
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules -Â a chemical called pyruvate. A small amount of ATP is formed during this process.Â
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to âburnâ the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP.  Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.Â
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.Â
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 â 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : Â cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called âsmallâ because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
1. The University of Sydney Page 1
Exploratory data
analysis
The basics
Presented by
Professor Peter Reimann
Centre for Research on Learning and
Cognition
2. The University of Sydney Page 2
EDA is a inquiry cycle
Generate
questions
Search for
answers
in the data
Refine
questions
Visualize, transform, model the data
EDA is an important
component of theory-driven,
problem-driven, and
curiosity-driven research.
3. The University of Sydney Page 3
Where do questions come from?
An important source of questions on data are hypotheses derived from theory:
Data Hypotheses Theory
Another source are problems:
Data Questions
Problem(
s)
Data Questions Data
A third source are data themselves:
4. The University of Sydney Page 4
Models of data
EDA plays a role in all three scenarios.
â Theories do not get compared with data as such, but with models of data:
Data Hypotheses TheoryData
model(s)
ED
A
Data Questions
Problem(
s)
Data
model(s)
ED
A
Questions
Data
model(s)
And similarly for the other cases:
Data
Data
model(s)
ED
A
5. The University of Sydney Page 5
Data are not âobjectiveâ
â Measurements and observations are not theory- or assumption-free;
â Thereâs more than one way to build a (statistical) model of any data
set;
â While the data may support a theory, they likely support many other
theories;
â While a data set may support a theory, it could also contain relation
that are contradicting the theory
Hence, even if your data are carefully selected and
measured, and you think you know them well, it is
important to look for the unexpected!
6. The University of Sydney Page 6
The exploratory perspective
Key assumption: The more one knows about the data, the more effectively
data can used to
â develop, test and refine theory,
â solve problems, and
â ask interesting questions.
To maximise what is learned from data, one needs to adhere to two principles:
â scepticism, and
â openness.
One should be sceptical, for instance about the assumption that specific
statistical parameters (i.e., summaries of data, such as the mean) reflect data
faithfully, and open to different interpretations of what the data say.
7. The University of Sydney Page 7
Be sceptical! Be open!
One reason to be sceptical
about statistics in particular
is Anscombeâs Quartet:
â Four datasets with (almost)
identical statistics, but
very different shapes.
By Ascombe https://commons.wikimedia.org/w/index.php?curid=9838454
8. The University of Sydney Page 8
(cont.)
â Statistics (= summative accounts of data) can be misleading
â Data analysis is not identical with statistics:
â Visual analysis should precede statistical analysis
Stay open to multiple interpretations!
â The confirmatory, or hypothesis-testing mode, to data analysis can
keep one from seeing what other patterns might exist in data.
In addition to asking:
â Do these data confirm or disconfirm my hypothesis about x?
Ask:
â What can these data tell me about x?
9. The University of Sydney Page 9
Model and outliers
The basic way of thinking about data:
Data = pattern + deviations
(model + outliers)
(smooth + rough)
Data analysis, including statistical analysis, means to partition data into
patterns/models/smooths and deviations/outliers/roughs
For any given data, there are in principle many ways to do this
partitioning, and there is no logical reason to a priori prefer one over the
other ï the analysis process is incremental, not one hypothesis testing
step.
10. The University of Sydney Page 10
Our tools for EDA
â dplyr: selecting, filtering, summarising data
â ggplot2: visualising data, patterns, trends.
11. The University of Sydney Page 11
Data selection with dplyr
Variable A (âŠ) Variable v
Observation
1
Value 1A (âŠ) Value 1v
Observation
2
Value 2A (âŠ) Value 2v
(âŠ) (âŠ) (âŠ) (âŠ)
Observation
o
Value oA (âŠ) Value ov
(2) filter on values
(3) arrange
by rows
(1) select variables
(4) mutate: create new variables
(5) sum-
marize
over
values
dplyr is made up out of 5 verbs:
12. The University of Sydney Page 12
âSentencesâ in dplyr
General format: verb(data frame, parameters)
â The result is a new data frame: new_frame <- verb(data,
parameter).
Examples:
â filter(flights, month == 1, day == 1)
â arrange(flights, year, month, day)
â select(flights, year, month, day)
â mutate(flights, gain = arr_delay - dep_delay,
speed = distance / air_time * 60)
â summarize(flights, delay = mean(dep_delay))
13. The University of Sydney Page 13
Boolean operations are supported for filtering
and selecting
! Is ânotâ, | is âorâ, & is
âandâ
filter(flights, !(arr_delay > 120 | dep_delay > 120))
filter(flights, arr_delay <= 120, dep_delay <= 120)
These two return the same observations:
For more on these commands, see for instance
https://www.youtube.com/watch?v=aywFompr1F4
14. The University of Sydney Page 14
Workbook
â The rest of this module is mainly in the workbook.
Editor's Notes
https://en.wikipedia.org/wiki/Anscombe's_quartet. The reason for some of this is that many statistics are very sensitive towards outliers. See in particular 3 and 4.