This document summarizes early European exploration and colonization efforts beginning in the 15th century. It discusses key explorers like Christopher Columbus, Ferdinand Magellan, and their voyages of discovery. It also outlines the conquests of the Aztec and Incan empires by the Spanish, led by conquistadors like Hernan Cortes and Francisco Pizarro. Furthermore, it examines the establishment of European colonies in the Americas and the devastating impacts on indigenous populations, including the trans-Atlantic slave trade that transported over 10 million Africans to the Americas between the 16th and 19th centuries.