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Research Ethics
Dr. Zaffar Ahmad Nadaf
Assistant Professor ©
School of Education
Central University of Kashmir
Research Ethics
• Ethics are broadly the set of rules, written and unwritten, that govern our
expectations of our own and others’ behaviour.
• Research ethics provides guidelines for the responsible conduct of research.
• Research ethics are the set of ethics that govern how scientific and other
research is performed at research institutions such as universities, and how it
is disseminated.
• It educates and monitors scientists/researchers conducting research to
ensure a high ethical standard.
Importance of Research Ethics
• They promote the aims of research, such as expanding knowledge.
• They support the values required for collaborative work, such as mutual respect and fairness.
This is essential because scientific research depends on collaboration between researchers
and groups.
• They mean that researchers can be held accountable for their actions. Many researchers are
supported by public money, and regulations on conflicts of interest, misconduct, and
research involving humans or animals are necessary to ensure that money is spent
appropriately.
• They ensure that the public can trust research. For people to support and fund research,
they have to be confident in it.
• They support important social and moral values, such as the principle of doing no harm to
others.
Summary of Some Ethical Principles:
• Honesty and Integrity
• Honestly report data, results, methods and procedures, and publication status.
• Do not fabricate, falsify, or misrepresent data.
• Keep your promises and agreements; act with sincerity;
• strive for consistency of thought and action.
• Means that you need to report your research honestly, and this applies to your methods
(what you did), your data, your results, and whether you have previously published any of it.
• You should not make up any data, including extrapolating unreasonably from some of your
results, or do anything which could be construed as trying to mislead anyone.
• It is better to undersell than over-exaggerate your findings.
Objectivity
• Strive to avoid bias in experimental design, data analysis, data interpretation, peer
review, personnel decisions, grant writing, expert testimony, and other aspects of
research.
• You should aim to avoid bias in any aspect of your research, including design, data
analysis, interpretation, and peer review.
• For example, you should never recommend as a peer reviewer someone you know, or
who you have worked with, and you should try to ensure that no groups are
inadvertently excluded from your research.
• This also means that you need to disclose any personal or financial interests that may
affect your research.
Carefulness:
• Avoid careless errors and negligence; carefully and critically examine your own work
and the work of your peers. Keep good records of research activities.
• Take care in carrying out your research to avoid careless mistakes.
• You should also review your work carefully and critically to ensure that your results
are credible.
• It is also important to keep full records of your research. If you are asked to act as a
peer reviewer, you should take the time to do the job effectively and fully.
Openness:
• Share data, results, ideas, tools, resources. Be open to criticism and new ideas.
• You should always be prepared to share your data and results, along with any
new tools that you have developed, when you publish your findings, as this
helps to further knowledge and advance science.
• You should also be open to criticism and new ideas
Respect for Intellectual Property:
• Honor patents, copyrights, and other forms of intellectual property.
• Do not use unpublished data, methods, or results without permission. Give credit
where credit is due.
• Never plagiarize.
• You should never plagiarise, or copy, other people’s work and try to pass it off as
your own.
• You should always ask for permission before using other people’s tools or methods,
unpublished data or results. Not doing so is plagiarism.
• Obviously, you need to respect copyrights and patents, together with other forms of
intellectual property, and always acknowledge contributions to your research. If in
doubt, acknowledge, to avoid any risk of plagiarism.
Confidentiality:
• Protect confidential communications, such as papers or grants submitted for
publication, personnel records, trade or military secrets, and patient records.
• You should respect anything that has been provided in confidence.
• You should also follow guidelines on protection of sensitive
information such as patient records.
Responsible Publication:
• Publish in order to advance research and scholarship, not to advance just
your own career. Avoid wasteful and duplicative publication.
• You should publish to advance to state of research and knowledge, and not
just to advance your career.
• This means, in essence, that you should not publish anything that is not new,
or that duplicates someone else’s work.
Animal Care:
• Show proper respect and care for animals when using them in research. Do
not conduct unnecessary or poorly designed animal experiments.
• If you are using animals in your research, you should always be sure that your
experiments are both necessary and well-designed.
• You should also show respect for the animals you are using, and make sure
that they are properly cared for.
Human Subjects Protection:
• When conducting research on human subjects, minimize harms and risks and
maximize benefits;
• respect human dignity, privacy, and autonomy.
• If your research involves people, you should make sure that you reduce any possible
harm to the minimum, and maximise the benefits both to participants and other
people.
• This means, for example, that you should not expose people to more tests than are
strictly necessary to fulfil your research aims.
• You should always respect human rights, including the right to privacy and
autonomy. You may need to take particular care with vulnerable groups, which
include, but are not limited to, children, older people, and those with learning
difficulties
• Legality:
• Know and obey relevant laws and institutional and governmental policies.
• You should always be aware of laws and regulations that govern your work, and be
sure that you conform to them.
• Non-Discrimination:
• Avoid discrimination against colleagues or students on the basis of sex, race,
ethnicity, or other factors that are not related to their scientific competence and
integrity.
• Responsible Mentoring:
• Help to educate, mentor, and advise students. Promote their welfare and allow them
to make their own decisions.
• Respect for Colleagues:
• Respect your colleagues and treat them fairly.
• Social Responsibility:
• Strive to promote social good and prevent or mitigate social harms through research,
public education, and advocacy.
• Competence:
• Maintain and improve your own professional competence and expertise through
lifelong education and learning; take steps to promote competence in science as a
whole.
Common Ethical Issues In Research And
Publication
• Research is the pillar of knowledge, and it constitutes an integral part of progress. In the fast-
expanding field of biomedical research, this has improved the quality and quantity of life.
• Historically, medical doctors have been in the privileged position to carry out research, especially in
clinical research which involves people.
• They are able to control “life and death” of patients and have free access to their confidential
information.
• Moreover, medical researchers have also enjoyed immunity from accountability due to high public
regard for science and medicine. This has resulted in some researchers conducting unethical
researches.
• For instance, in World War II, medical doctors had conducted unethical experiments on human in the
name of science, resulting in harm and even death in some cases.
• More recently, the involvement of pharmaceutical industry in clinical trials have raised issues about
how to safeguard patient’s care and to ensure the published research findings are objective.
Study Design and Ethics Approval
• Good research should be well adjusted, well-planned, appropriately designed, and
ethically approved.
• To conduct research to a lower standard may constitute misconduct.
• This may appear to be a stringent criterion, but it highlights the basic requirement of
a researcher is to conduct a research responsibly.
• To achieve this, a research protocol should be developed and adhered to.
• It must be carefully agreed to by all contributors and collaborators, and the precise
roles of each team member should be spelled out early, including matters of
authorship and publications.
• Research should seek to answer specific questions, rather than just collect data.
• It is essential to obtain approval from the Institutional Review Board, or Ethics
Committee, of the respective organisations for studies involving people, medical
records, and anonymised human tissues.
• The research proposal should discuss potential ethical issues pertaining to the
research.
• The researchers should pay special attention to vulnerable subjects to avoid breech
of ethical codes (e.g. children, prisoners, pregnant women, mentally challenged,
educationally and economically disadvantaged).
• Consent should be explained and obtained from the subjects or guardians, and steps
should be taken to ensure confidentiality of information provided by the subjects.
Data Analysis
• It is the responsibility of the researcher to analyse the data appropriately.
• Although inappropriate analysis does not necessarily amount to misconduct,
intentional omission of result may cause misinterpretation and mislead the readers.
• Fabrication and falsification of data do constitute misconduct. For example, in a
clinical trial, if a drug is found to be ineffective, this study should be reported.
• There is a tendency for the researchers to under-report negative research
findings, and this is partly contributed by pressure from the pharmaceutical industry
which funds the clinical trial.
• To ensure appropriate data analysis, all sources and methods used to obtain
and analyse data should be fully disclosed.
• Failure to do so may lead the readers to misinterpret the results without
considering possibility of the study being underpowered.
• The discussion section of a paper should mention any issues of bias, and
explain how they have been dealt with in the design and interpretation of the
study.
Authorship
• There is no universally agreed definition of authorship.
• It is generally agreed that an author should have made substantial contribution to
the intellectual content, including
• Conceptualising and designing the study;
• Acquiring, Analysing and Interpreting the data.
• The author should also take responsibility to certify that the manuscript represents
valid work and take public responsibility for the work.
• Finally, an author is usually involved in drafting or revising the manuscript, as well as
approving the submitted manuscript.
• Data collection, editing of grammar and language, and other routine works
by itself, do not deserve an authorship.
• It is crucial to decide early on in the planning of a research who will be
credited as authors, as contributors, and who will be acknowledged.
• It is also advisable to read carefully the “Advice to Authors” of the target
journal which may serve as a guide to the issue of authorship.
Conflicts of Interest
• This happens when researchers have interests that are not fully apparent and that
may influence their judgments on what is published.
• These conflicts include personal, commercial, political, academic or financial interest.
• Financial interests may include employment, research funding, stock or share
ownership, payment for lecture or travel, consultancies and company support for
staff.
• This issue is especially pertinent in biomedical research where a substantial number
of clinical trials are funded by pharmaceutical company.
• Such interests, where relevant, should be discussed in the early stage of research.
• The researchers need to take extra effort to ensure that their conflicts of interest do
not influence the methodology and outcome of the research.
• It would be useful to consult an independent researcher, or Ethics Committee, on
this issue if in doubt.
• When publishing, these conflicts of interest should be declared to editors, and
readers will judge for themselves whether the research findings are trustworthy.
Redundant Publication and Plagiarism
• Redundant publication occurs when two or more papers, without full cross
reference, share the same hypothesis, data, discussion points, or conclusions.
• However, previous publication of an abstract during the proceedings of
meetings does not preclude subsequent submission for publication, but full
disclosure should be made at the time of submission. This is also known as
self-plagiarism.
• In the increasing competitive environment where appointments, promotions
and grant applications are strongly influenced by publication record,
researchers are under intense pressure to publish, and a growing minority is
seeking to bump up their CV through dishonest means.
• On the other hand, plagiarism ranges from unreferenced use of others’
published and unpublished ideas, including research grant applications to
submission under “new” authorship of a complete paper, sometimes in
different language.
• Therefore, it is important to disclose all sources of information, and if large
amount of other people’s written or illustrative materials is to be used,
permission must be sought.
CONCLUSION
• It is the duty of the researcher to ensure that research is conducted in an ethical and
responsible manner from planning to publication.
• Researchers and authors should familiarise themselves with these principles and
follows them strictly.
• Any potential ethical issues in research and publication should be discussed openly
within the research team.
• If in doubt, it is advisable to consult the respective institutional review board (IRB)
for their expert opinions.
References
• Human D, Fluss SS. World Medical Association; 2001. The World Medical Association
Declaration of Helsinki: historical and contemporary perspectives. [Google Scholar]
• Lexchin J, Bero LA, Djulbegovic B, Clark O. Pharmaceutical industry sponsorship and research
outcome and quality. BMJ. 2003;326:1167–70. [PMC free article] [PubMed] [Google Scholar]
• World Medical association. 2004. Declaration of Helsinki: Ethical Principles for Medical Research
Involving Human Subjects. [PubMed] [Google Scholar]
• Committee on Publication Ethics (COPE) 2005. Guidelines on good publication and the Code
of Conduct. [Google Scholar]
• Smith R. Medical journals are an extension of the marketing arm of pharmaceutical
companies. PLoS Med. 2005;2:100–2. [PMC free article] [PubMed] [Google Scholar]
• Medical Research Council. London: MRC; 1998. MRC Guidelines for good clinical practice in
clinical trials. [Google Scholar]
• Giles J. Taking on the cheats. Nature. 2005;435:258–9. [PubMed] [Google Scholar]

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Ethics in Research.pptx

  • 1. Research Ethics Dr. Zaffar Ahmad Nadaf Assistant Professor © School of Education Central University of Kashmir
  • 2. Research Ethics • Ethics are broadly the set of rules, written and unwritten, that govern our expectations of our own and others’ behaviour. • Research ethics provides guidelines for the responsible conduct of research. • Research ethics are the set of ethics that govern how scientific and other research is performed at research institutions such as universities, and how it is disseminated. • It educates and monitors scientists/researchers conducting research to ensure a high ethical standard.
  • 3. Importance of Research Ethics • They promote the aims of research, such as expanding knowledge. • They support the values required for collaborative work, such as mutual respect and fairness. This is essential because scientific research depends on collaboration between researchers and groups. • They mean that researchers can be held accountable for their actions. Many researchers are supported by public money, and regulations on conflicts of interest, misconduct, and research involving humans or animals are necessary to ensure that money is spent appropriately. • They ensure that the public can trust research. For people to support and fund research, they have to be confident in it. • They support important social and moral values, such as the principle of doing no harm to others.
  • 4. Summary of Some Ethical Principles: • Honesty and Integrity • Honestly report data, results, methods and procedures, and publication status. • Do not fabricate, falsify, or misrepresent data. • Keep your promises and agreements; act with sincerity; • strive for consistency of thought and action. • Means that you need to report your research honestly, and this applies to your methods (what you did), your data, your results, and whether you have previously published any of it. • You should not make up any data, including extrapolating unreasonably from some of your results, or do anything which could be construed as trying to mislead anyone. • It is better to undersell than over-exaggerate your findings.
  • 5. Objectivity • Strive to avoid bias in experimental design, data analysis, data interpretation, peer review, personnel decisions, grant writing, expert testimony, and other aspects of research. • You should aim to avoid bias in any aspect of your research, including design, data analysis, interpretation, and peer review. • For example, you should never recommend as a peer reviewer someone you know, or who you have worked with, and you should try to ensure that no groups are inadvertently excluded from your research. • This also means that you need to disclose any personal or financial interests that may affect your research.
  • 6. Carefulness: • Avoid careless errors and negligence; carefully and critically examine your own work and the work of your peers. Keep good records of research activities. • Take care in carrying out your research to avoid careless mistakes. • You should also review your work carefully and critically to ensure that your results are credible. • It is also important to keep full records of your research. If you are asked to act as a peer reviewer, you should take the time to do the job effectively and fully.
  • 7. Openness: • Share data, results, ideas, tools, resources. Be open to criticism and new ideas. • You should always be prepared to share your data and results, along with any new tools that you have developed, when you publish your findings, as this helps to further knowledge and advance science. • You should also be open to criticism and new ideas
  • 8. Respect for Intellectual Property: • Honor patents, copyrights, and other forms of intellectual property. • Do not use unpublished data, methods, or results without permission. Give credit where credit is due. • Never plagiarize. • You should never plagiarise, or copy, other people’s work and try to pass it off as your own. • You should always ask for permission before using other people’s tools or methods, unpublished data or results. Not doing so is plagiarism. • Obviously, you need to respect copyrights and patents, together with other forms of intellectual property, and always acknowledge contributions to your research. If in doubt, acknowledge, to avoid any risk of plagiarism.
  • 9. Confidentiality: • Protect confidential communications, such as papers or grants submitted for publication, personnel records, trade or military secrets, and patient records. • You should respect anything that has been provided in confidence. • You should also follow guidelines on protection of sensitive information such as patient records.
  • 10. Responsible Publication: • Publish in order to advance research and scholarship, not to advance just your own career. Avoid wasteful and duplicative publication. • You should publish to advance to state of research and knowledge, and not just to advance your career. • This means, in essence, that you should not publish anything that is not new, or that duplicates someone else’s work.
  • 11. Animal Care: • Show proper respect and care for animals when using them in research. Do not conduct unnecessary or poorly designed animal experiments. • If you are using animals in your research, you should always be sure that your experiments are both necessary and well-designed. • You should also show respect for the animals you are using, and make sure that they are properly cared for.
  • 12. Human Subjects Protection: • When conducting research on human subjects, minimize harms and risks and maximize benefits; • respect human dignity, privacy, and autonomy. • If your research involves people, you should make sure that you reduce any possible harm to the minimum, and maximise the benefits both to participants and other people. • This means, for example, that you should not expose people to more tests than are strictly necessary to fulfil your research aims. • You should always respect human rights, including the right to privacy and autonomy. You may need to take particular care with vulnerable groups, which include, but are not limited to, children, older people, and those with learning difficulties
  • 13. • Legality: • Know and obey relevant laws and institutional and governmental policies. • You should always be aware of laws and regulations that govern your work, and be sure that you conform to them. • Non-Discrimination: • Avoid discrimination against colleagues or students on the basis of sex, race, ethnicity, or other factors that are not related to their scientific competence and integrity.
  • 14. • Responsible Mentoring: • Help to educate, mentor, and advise students. Promote their welfare and allow them to make their own decisions. • Respect for Colleagues: • Respect your colleagues and treat them fairly. • Social Responsibility: • Strive to promote social good and prevent or mitigate social harms through research, public education, and advocacy. • Competence: • Maintain and improve your own professional competence and expertise through lifelong education and learning; take steps to promote competence in science as a whole.
  • 15. Common Ethical Issues In Research And Publication • Research is the pillar of knowledge, and it constitutes an integral part of progress. In the fast- expanding field of biomedical research, this has improved the quality and quantity of life. • Historically, medical doctors have been in the privileged position to carry out research, especially in clinical research which involves people. • They are able to control “life and death” of patients and have free access to their confidential information. • Moreover, medical researchers have also enjoyed immunity from accountability due to high public regard for science and medicine. This has resulted in some researchers conducting unethical researches. • For instance, in World War II, medical doctors had conducted unethical experiments on human in the name of science, resulting in harm and even death in some cases. • More recently, the involvement of pharmaceutical industry in clinical trials have raised issues about how to safeguard patient’s care and to ensure the published research findings are objective.
  • 16. Study Design and Ethics Approval • Good research should be well adjusted, well-planned, appropriately designed, and ethically approved. • To conduct research to a lower standard may constitute misconduct. • This may appear to be a stringent criterion, but it highlights the basic requirement of a researcher is to conduct a research responsibly. • To achieve this, a research protocol should be developed and adhered to. • It must be carefully agreed to by all contributors and collaborators, and the precise roles of each team member should be spelled out early, including matters of authorship and publications. • Research should seek to answer specific questions, rather than just collect data.
  • 17. • It is essential to obtain approval from the Institutional Review Board, or Ethics Committee, of the respective organisations for studies involving people, medical records, and anonymised human tissues. • The research proposal should discuss potential ethical issues pertaining to the research. • The researchers should pay special attention to vulnerable subjects to avoid breech of ethical codes (e.g. children, prisoners, pregnant women, mentally challenged, educationally and economically disadvantaged). • Consent should be explained and obtained from the subjects or guardians, and steps should be taken to ensure confidentiality of information provided by the subjects.
  • 18. Data Analysis • It is the responsibility of the researcher to analyse the data appropriately. • Although inappropriate analysis does not necessarily amount to misconduct, intentional omission of result may cause misinterpretation and mislead the readers. • Fabrication and falsification of data do constitute misconduct. For example, in a clinical trial, if a drug is found to be ineffective, this study should be reported. • There is a tendency for the researchers to under-report negative research findings, and this is partly contributed by pressure from the pharmaceutical industry which funds the clinical trial.
  • 19. • To ensure appropriate data analysis, all sources and methods used to obtain and analyse data should be fully disclosed. • Failure to do so may lead the readers to misinterpret the results without considering possibility of the study being underpowered. • The discussion section of a paper should mention any issues of bias, and explain how they have been dealt with in the design and interpretation of the study.
  • 20. Authorship • There is no universally agreed definition of authorship. • It is generally agreed that an author should have made substantial contribution to the intellectual content, including • Conceptualising and designing the study; • Acquiring, Analysing and Interpreting the data. • The author should also take responsibility to certify that the manuscript represents valid work and take public responsibility for the work. • Finally, an author is usually involved in drafting or revising the manuscript, as well as approving the submitted manuscript.
  • 21. • Data collection, editing of grammar and language, and other routine works by itself, do not deserve an authorship. • It is crucial to decide early on in the planning of a research who will be credited as authors, as contributors, and who will be acknowledged. • It is also advisable to read carefully the “Advice to Authors” of the target journal which may serve as a guide to the issue of authorship.
  • 22. Conflicts of Interest • This happens when researchers have interests that are not fully apparent and that may influence their judgments on what is published. • These conflicts include personal, commercial, political, academic or financial interest. • Financial interests may include employment, research funding, stock or share ownership, payment for lecture or travel, consultancies and company support for staff. • This issue is especially pertinent in biomedical research where a substantial number of clinical trials are funded by pharmaceutical company.
  • 23. • Such interests, where relevant, should be discussed in the early stage of research. • The researchers need to take extra effort to ensure that their conflicts of interest do not influence the methodology and outcome of the research. • It would be useful to consult an independent researcher, or Ethics Committee, on this issue if in doubt. • When publishing, these conflicts of interest should be declared to editors, and readers will judge for themselves whether the research findings are trustworthy.
  • 24. Redundant Publication and Plagiarism • Redundant publication occurs when two or more papers, without full cross reference, share the same hypothesis, data, discussion points, or conclusions. • However, previous publication of an abstract during the proceedings of meetings does not preclude subsequent submission for publication, but full disclosure should be made at the time of submission. This is also known as self-plagiarism. • In the increasing competitive environment where appointments, promotions and grant applications are strongly influenced by publication record, researchers are under intense pressure to publish, and a growing minority is seeking to bump up their CV through dishonest means.
  • 25. • On the other hand, plagiarism ranges from unreferenced use of others’ published and unpublished ideas, including research grant applications to submission under “new” authorship of a complete paper, sometimes in different language. • Therefore, it is important to disclose all sources of information, and if large amount of other people’s written or illustrative materials is to be used, permission must be sought.
  • 26. CONCLUSION • It is the duty of the researcher to ensure that research is conducted in an ethical and responsible manner from planning to publication. • Researchers and authors should familiarise themselves with these principles and follows them strictly. • Any potential ethical issues in research and publication should be discussed openly within the research team. • If in doubt, it is advisable to consult the respective institutional review board (IRB) for their expert opinions.
  • 27. References • Human D, Fluss SS. World Medical Association; 2001. The World Medical Association Declaration of Helsinki: historical and contemporary perspectives. [Google Scholar] • Lexchin J, Bero LA, Djulbegovic B, Clark O. Pharmaceutical industry sponsorship and research outcome and quality. BMJ. 2003;326:1167–70. [PMC free article] [PubMed] [Google Scholar] • World Medical association. 2004. Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects. [PubMed] [Google Scholar] • Committee on Publication Ethics (COPE) 2005. Guidelines on good publication and the Code of Conduct. [Google Scholar] • Smith R. Medical journals are an extension of the marketing arm of pharmaceutical companies. PLoS Med. 2005;2:100–2. [PMC free article] [PubMed] [Google Scholar] • Medical Research Council. London: MRC; 1998. MRC Guidelines for good clinical practice in clinical trials. [Google Scholar] • Giles J. Taking on the cheats. Nature. 2005;435:258–9. [PubMed] [Google Scholar]