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METABOLISM ENDOCRINE SYSTEM
ENDOCRINE GLANDS ,[object Object],PROLACTIN/ LTH ,[object Object],GH/ SOMATOTROPIN ,[object Object],FSH,LH ,[object Object],ACTH LOBE ,[object Object],TSH ,[object Object],[object Object],FUNCTIONS HORMONES ENDOCRINE GLAND
ENDOCRINE GLANDS ,[object Object],MSH ,[object Object],[object Object],[object Object],[object Object],OXYTOCIN ,[object Object],ADH ,[object Object],[object Object],[object Object],FUNCTION HORMONE ENDOCRINE GLAND
ENDOCRINE GLANDS ,[object Object],SEX HORMONES ,[object Object],[object Object],[object Object],[object Object],[object Object],CORTISOL ,[object Object],[object Object],[object Object],ALDOSTERONE ADRENAL  CORTEX FUNCTION HORMONES ENDOCRINE GLAND
ENDOCRINE GLANDS ,[object Object],[object Object],[object Object],[object Object],EPINEPHRINE NOR- EPINEPHRINE ADRENAL  MEDULLA FUNCTION HORMONE ENDOCRINE GLAND
 
ENDOCRINE GLANDS ,[object Object],PTH PARA- THYROID ,[object Object],THYRO- CALCITONIN ,[object Object],[object Object],[object Object],T3 & T4’ THYROID FUNCTION HORMONE ENDOCRINE GLAND
ENDOCRINE GLANDS ,[object Object],[object Object],[object Object],GLUCAGON ,[object Object],[object Object],[object Object],[object Object],[object Object],INSULIN ,[object Object],[object Object],[object Object],FUNCTION HORMONE ENDOCRINE GLAND
ENDOCRINE GLANDS ,[object Object],[object Object],[object Object],TESTOS- TERONE TESTES ,[object Object],[object Object],[object Object],[object Object],ESTROGEN & PROGES- TERONE OVARIES FUNCTION HORMONES ENDOCRINE GLAND
HORMONE REGULATION ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
NEGATIVE FEEDBACK MECHANISM ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
NEGATIVE FEEDBACK MECHANISM ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CASE STUDY ,[object Object],[object Object],[object Object]
CASE STUDY ,[object Object],[object Object]
PLANNING ,[object Object],[object Object],[object Object],[object Object],[object Object]
STEROID THERAPY ,[object Object],[object Object],ENDOGENOUS CORTISOL PRODUCTION &  RELEASE BY ADRENAL MEDULLA ADRENAL ATROPHY
STEROID THERAPY ,[object Object],[object Object],[object Object],[object Object],[object Object]
STEROID THERAPY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
STEROID THERAPY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
STEROID THERAPY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
STEROID THERAPY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
STEROID THERAPY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
STEROID THERAPY ,[object Object],[object Object],ENDOGENOUS CORTISOL PRODUCTION &  RELEASE BY ADRENAL MEDULLA ADRENAL ATROPHY
STEROID THERAPY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ANTERIOR PITUITARY  DISTURBANCES ,[object Object],[object Object]
HYPOPITUITARISM ANTERIOR LOBE ,[object Object],[object Object],[object Object]
HYPERPITUITARISM ANTERIOR LOBE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PITUITARY ANTERIOR LOBE ,[object Object],[object Object],PROLACTIN ,[object Object],[object Object],FSH ,[object Object],[object Object],TSH ,[object Object],[object Object],ACTH ,[object Object],[object Object],[object Object],[object Object],GH HYPER FXN HYPO FXN HORMONE
MANAGEMENT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
POSTERIOR PITUITARY DISTURBANCES ,[object Object],[object Object]
DIABETES INSIPIDUS  ABSOLUTE / PARTIAL DEFICIENCY OF VASOPRESSIN ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DIABETES INSIPIDUS  ABSOLUTE / PARTIAL DEFICIENCY OF VASOPRESSIN ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
SYNDROME OF INAPPROPRIATE ADH ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
SYNDROME OF INAPPROPRIATE ADH ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Mission possible
THYROID GLAND ,[object Object],[object Object],[object Object],[object Object],[object Object]
THYROID DISTURBANCES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
THYROID DISTURBANCES GRAVE’S DSE or Exophthalmic goiter ,[object Object],[object Object],[object Object],HYPERTHYROIDISM HYPOTHYROIDISM
EFFECTS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],HYPERTHYROIDISM HYPOTHYROIDISM
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],HYPERTHYROIDISM HYPOTHYROIDISM
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],HYPERTHYROIDISM HYPOTHYROIDISM
MANAGEMENT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],HYPERTHYROIDISM HYPOTHYROIDISM
ANTITHYROID MEDICATIONS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
SUBTOTAL THYROIDECTOMY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
SUBTOTAL THYROIDECTOMY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
TETANY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
THYROID STORM / CRISIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
THYROID STORM / CRISIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
VARIANTS OF HYPERTHYROIDISM ,[object Object],[object Object],[object Object]
GRAVE’S DISEASE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
OPHTHALMOPATHY ,[object Object],[object Object],[object Object],[object Object]
DERMOPATHY ,[object Object],[object Object],[object Object],[object Object],[object Object]
THYROIDITIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
GOITER ,[object Object],[object Object],[object Object],[object Object]
TOXIC NODULAR GOITER ,[object Object],[object Object],[object Object],[object Object],[object Object]
NON-TOXIC GOITER ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
NON-TOXIC GOITER ,[object Object],[object Object],[object Object],[object Object],[object Object],IODINE DEFICIENCY OR  INTAKE OF GOITROGENIC SUBSTANCES
NON-TOXIC GOITER ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
MYXEDEMA COMA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
MYXEDEMA COMA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
MYXEDEMA COMA ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
PARATHYROID GLAND ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PARATHYROID DISORDERS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
HYPOPARATHYROIDISM ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
HYPOPARATHYROIDISM ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
HYPOPARATHYROIDISM ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
HYPERPARATHYROIDISM ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
HYPERPARATHYROIDISM ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
HYPERPARATHYROIDISM ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ADRENAL GLAND ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ADRENAL GLAND ,[object Object],[object Object],SEX HORMONE ,[object Object],[object Object],[object Object],GLUCO- CORTICOIDS ,[object Object],[object Object],ALDOSTERONE FUNCTION HORMONE
SYMPTOMATOLOGY ,[object Object],[object Object],[object Object],[object Object],[object Object]
SYMPTOMATOLOGY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
SYMPTOMATOLOGY ,[object Object],[object Object],[object Object],[object Object]
ADRENAL CORTEX DISORERS ,[object Object],[object Object],[object Object],[object Object]
ADRENAL INSUFFICIENCY ADDISON’S DISEASE ,[object Object]
ADRENAL CRISIS ,[object Object],[object Object]
ADRENAL CRISIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ADRENAL CRISIS ,[object Object],[object Object],[object Object],[object Object]
ADRENAL CRISIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
ADRENAL CRISIS ,[object Object],[object Object],[object Object],[object Object]
ADRENAL CRISIS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CUSHING’S SYNDROME ,[object Object],[object Object],[object Object],[object Object]
CUSHING’S SYNDROME ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CUSHING’S SYNDROME ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CUSHING’S SYNDROME ,[object Object],[object Object],[object Object],[object Object],[object Object]
ALDOSTERONISM ,[object Object],[object Object],[object Object]
CONN’S SYNDROME ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
SECONDARY ALDOSTERONISM ,[object Object],[object Object]
ADRENAL MEDULLA ,[object Object],[object Object],[object Object]
PHEOCHROMOCYTOMA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
VMA IN 24H URINE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PHEOCHROMOCYTOMA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PANCREAS ,[object Object],[object Object],[object Object]
DIABETES MILLETUS ,[object Object],[object Object],[object Object],[object Object],[object Object]
DIABETES MILLETUS PATHOPHYSIOLOGY REDUCED /NO INSULIN HYPERGLYCEMIA GLUCOSURIA WEIGHT LOSS OSMOTIC DIURESIS POLYURIA CELLULAR  HUNGER POLYPHAGIA POLYDIPSIA LIPOLYSIS OSMOTIC DEHYDRATION
DIABETES MILLETUS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DIABETES MILLETUS ,[object Object],CONCEPTION EVIDENCE OF GLUCOSE METABOLISM ALTERATION
DIABETES MILLETUS ,[object Object],PREDIABETES NO STRESS STRESS NORMAL GLUCOSE METABOLISM OVERT DIABETES
DIABETES MILLETUS ,[object Object],SUBCLINICAL GTT IS ABNORMAL NO STRESS STRESS ASYMPTOMATIC SYMPTOMATIC
DIABETES MILLETUS ,[object Object],CHEMICAL PERSISTENT  INCREASED  FBS WITH OR WITHOUT STRESS SYMPTOMATIC
DIABETES MILLETUS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DIABETES MILLETUS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
2 HR POSTPRANDIAL BLOOD SUGAR ,[object Object],[object Object]
OGTT ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
GLYCOSYLATED HEMOGLOBIN ,[object Object],[object Object],[object Object],[object Object]
DIABETES MILLETUS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DIABETES MILLETUS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DIABETES MILLETUS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DIABETES MILLETUS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
LIPODYSTROPHY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
INSULIN THERAPY & HORMONAL ACTIVITY ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
SURPRISE!!!
ACUTE COMPLICATIONS  OF DIABETES MILLETUS ,[object Object],[object Object],[object Object],[object Object],[object Object]
D.K.A. PATHOPHYSIOLOGY NO INSULIN MARKED HYPERGLYCEMIA GLUCOSURIA WEIGHT   LOSS OSMOTIC DIURESIS POLYURIA CELLULAR  HUNGER POLYPHAGIA POLYDIPSIA LIPOLYSIS OSMOTIC DEHYDRATION KETOACIDOSIS
D.K.A. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
D.K.A. ,[object Object],[object Object],[object Object],[object Object],[object Object]
INSULIN SHOCK ,[object Object],[object Object],[object Object],[object Object],[object Object]
INSULIN SHOCK ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
INSULIN SHOCK ,[object Object],[object Object],[object Object],[object Object],[object Object]
HHONK PATHOPHYSIOLOGY Very insufficient INSULIN MARKED HYPERGLYCEMIA GLUCOSURIA WEIGHT   LOSS OSMOTIC DIURESIS POLYURIA CELLULAR  HUNGER POLYPHAGIA POLYDIPSIA LIPOLYSIS Without KETOSIS SEVERE OSMOTIC DEHYDRATION
HHONK ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
LACTIC ACIDOSIS SEVERE TISSUE ANOXIA LACTIC ACID PRODUCTION AGGRAVATION OF EXISTING METABOLIC ACIDOSIS
SOMOGYI EFFECT TOO MUCH INSULIN HYPOGLYCEMIA GLUCAGON IS RELEASED LIPOLYSIS GLUCONEOGENESIS GLYCOGENOLYSIS REBOUND HYPERGLYCEMIA + KETOSIS
CHRONIC COMPLICATIONS OF DIABETES MILLETUS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
CHRONIC COMPLICATIONS OF DIABETES MILLETUS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
GOD BLESS

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Endocrine Ppt

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  • 97. DIABETES MILLETUS PATHOPHYSIOLOGY REDUCED /NO INSULIN HYPERGLYCEMIA GLUCOSURIA WEIGHT LOSS OSMOTIC DIURESIS POLYURIA CELLULAR HUNGER POLYPHAGIA POLYDIPSIA LIPOLYSIS OSMOTIC DEHYDRATION
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  • 116. D.K.A. PATHOPHYSIOLOGY NO INSULIN MARKED HYPERGLYCEMIA GLUCOSURIA WEIGHT LOSS OSMOTIC DIURESIS POLYURIA CELLULAR HUNGER POLYPHAGIA POLYDIPSIA LIPOLYSIS OSMOTIC DEHYDRATION KETOACIDOSIS
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  • 122. HHONK PATHOPHYSIOLOGY Very insufficient INSULIN MARKED HYPERGLYCEMIA GLUCOSURIA WEIGHT LOSS OSMOTIC DIURESIS POLYURIA CELLULAR HUNGER POLYPHAGIA POLYDIPSIA LIPOLYSIS Without KETOSIS SEVERE OSMOTIC DEHYDRATION
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  • 124. LACTIC ACIDOSIS SEVERE TISSUE ANOXIA LACTIC ACID PRODUCTION AGGRAVATION OF EXISTING METABOLIC ACIDOSIS
  • 125. SOMOGYI EFFECT TOO MUCH INSULIN HYPOGLYCEMIA GLUCAGON IS RELEASED LIPOLYSIS GLUCONEOGENESIS GLYCOGENOLYSIS REBOUND HYPERGLYCEMIA + KETOSIS
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