EMERGENCY CONTRACEPTION
Sathyashree D, Coimbatore Medical College
AGENDA
Introduction
Indications
Mode of action
Methods of EC
Summary
References
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INTRODUCTION
• Synonyms: Postcoital contraception,Interceptives
• Postcoital contraceptive agents are the methods
used after unsafe coitus which prevent pregnancy
by interfering with fertilization or implantation.
• Emergency contraception should be used mainly
as ‘backup’ plan and not used as a regular
contraceptive technique.
INTRODUCTION-
CONTINUED
Emergency contraception cannot be used as
an ongoing method of contraception because:
 Relatively high failure rates
 High incidence of irregular bleeding
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INDICATIONS
o Unprotected Sexual Intercourse
o Accidental rupture of condom
o Missed Pill
o Following Rape
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MODE OF ACTION
HORMONES:
 Delay ovulation if taken soon after intercourse
 Cause corpus luteolysis
 Bring about cervical mucus changes and endometrial
atrophy
COPPER-T IUCD
Prevent implantation of fertilized ovum
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METHODS OF EMERGENCY CONTRACEPTION
EMERGENCY
CONTRACEPTION
LNG Tablets
RU486(Mifepristone)
Ulipristal
Centchroman
Prostaglandins
Copper-T IUCD
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LNG TABLETS
USE
• 0.75 mg, two doses
given at 12 hours
interval.
• Should be taken within
72 hours,may be taken
upto 120 hours.
ADVANTAGES
• No estrogen and
associated side effects
• Can be offered to
hypertensive, cardiac,
diabetic and lactating
woman
• No foetal adverse
effects
CONTRAINDICATIONS
• Liver disease
• Women with history of
thrombophlebitis and
migraine
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LEVONORGESTREL (E.
PILLS)
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RU486(MIFEPRISTONE)
• Single dose of 25-50 mg is effective
in preventing pregnancy
• Steroid with an affinity for
progesterone receptors.
• MOA: Causes shedding and
sloughing of decidua and prevents
implantation
• Disadvantages:
 Does not prevent ectopic
pregnancy
 Expensive
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ULIPRISTAL
Synthetic progesterone
hormone receptor regulator
MOA:Inhibits ovulation and
prevents implantation
30 mg tablet should be taken
within 5 days
2% pregnancy rate
Side effects: Headache,Mood
changes
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COPPER-T IUCD
Inserted within 5 days of unprotected
intercourse can prevent implantation of
a fertilized ovum
ADVANTAGES:
 Cheap
 Failure rate is 0.1%
 Remain as on-going contraceptive
for 3-5 years
It is the gold standard method to be
offered to all women for EC.
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SUMMARY
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REFERENCES
 Howkins and Bourne SHAW’s Textbook of
Gynaecology,17th Edition
 D C Dutta’s Textbook of Gynaecology,7th Edition
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THANK YOU
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EMERGENCY CONTRACEPTION..pptx

  • 1.
    EMERGENCY CONTRACEPTION Sathyashree D,Coimbatore Medical College
  • 2.
    AGENDA Introduction Indications Mode of action Methodsof EC Summary References 20XX Presentation title 2
  • 3.
    20XX Presentation title3 INTRODUCTION • Synonyms: Postcoital contraception,Interceptives • Postcoital contraceptive agents are the methods used after unsafe coitus which prevent pregnancy by interfering with fertilization or implantation. • Emergency contraception should be used mainly as ‘backup’ plan and not used as a regular contraceptive technique.
  • 4.
    INTRODUCTION- CONTINUED Emergency contraception cannotbe used as an ongoing method of contraception because:  Relatively high failure rates  High incidence of irregular bleeding 20XX Presentation title 4
  • 5.
    INDICATIONS o Unprotected SexualIntercourse o Accidental rupture of condom o Missed Pill o Following Rape 20XX Presentation title 5
  • 6.
    MODE OF ACTION HORMONES: Delay ovulation if taken soon after intercourse  Cause corpus luteolysis  Bring about cervical mucus changes and endometrial atrophy COPPER-T IUCD Prevent implantation of fertilized ovum 20XX Presentation title 6
  • 7.
    METHODS OF EMERGENCYCONTRACEPTION EMERGENCY CONTRACEPTION LNG Tablets RU486(Mifepristone) Ulipristal Centchroman Prostaglandins Copper-T IUCD 20XX Presentation title 7
  • 8.
    LNG TABLETS USE • 0.75mg, two doses given at 12 hours interval. • Should be taken within 72 hours,may be taken upto 120 hours. ADVANTAGES • No estrogen and associated side effects • Can be offered to hypertensive, cardiac, diabetic and lactating woman • No foetal adverse effects CONTRAINDICATIONS • Liver disease • Women with history of thrombophlebitis and migraine 20XX Presentation title 8
  • 9.
  • 10.
    RU486(MIFEPRISTONE) • Single doseof 25-50 mg is effective in preventing pregnancy • Steroid with an affinity for progesterone receptors. • MOA: Causes shedding and sloughing of decidua and prevents implantation • Disadvantages:  Does not prevent ectopic pregnancy  Expensive 20XX Presentation title 10
  • 11.
    ULIPRISTAL Synthetic progesterone hormone receptorregulator MOA:Inhibits ovulation and prevents implantation 30 mg tablet should be taken within 5 days 2% pregnancy rate Side effects: Headache,Mood changes 20XX Presentation title 11
  • 12.
    COPPER-T IUCD Inserted within5 days of unprotected intercourse can prevent implantation of a fertilized ovum ADVANTAGES:  Cheap  Failure rate is 0.1%  Remain as on-going contraceptive for 3-5 years It is the gold standard method to be offered to all women for EC. 20XX Presentation title 12
  • 13.
  • 14.
    REFERENCES  Howkins andBourne SHAW’s Textbook of Gynaecology,17th Edition  D C Dutta’s Textbook of Gynaecology,7th Edition 20XX Presentation title 14
  • 15.