Eicosanoids are synthesized from polyunsaturated fatty acids with 20 carbon atoms. They include prostaglandins, thromboxanes, leukotrienes, and others. Eicosanoids function as local hormones that regulate processes like inflammation, smooth muscle contraction, and blood pressure. They are synthesized in tissues through two pathways and have short half-lives, playing important roles before being metabolized and excreted. Eicosanoids impact various body systems like the cardiovascular, respiratory, gastrointestinal, and reproductive systems. Pharmaceuticals can target eicosanoid synthesis and receptors to treat conditions like ulcers, induction of labor, and erectile dysfunction.