Ebola virus disease was first identified in 1976 during outbreaks in Sudan and Zaire. It is caused by the Ebola virus and primarily affects humans and other primates. The virus spreads through direct contact with bodily fluids of infected individuals or animals. While its natural reservoir is unknown, fruit bats are suspected. There have been several outbreaks since 1976, with a major 2013-2014 outbreak in West Africa resulting in over 6,000 confirmed human deaths. Currently there is no approved vaccine or treatment, though supportive care is given to help fight secondary infections.

2.  Ebola virus disease is also called Ebola hemorrhagic
fever, or simply Ebola.
 Disease caused by Ebola virus.

3. History
 It was identified in 1976, when two outbreaks
occurred in Sudan and Zaire (areas near Africa)

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sudan zaire
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mortility

5. Introduction
 In 1979, it was found in Africa and no clinical case has
been found for 15 years.
 Another strain of Ebola was isolated in 1989 during an
outbreak of infection of monkeys named Macaca
fascicularus.

6. Reserviors

7. Structure
 The EBOV genome is a single stranded RNA
 19,000 nucleotides
 They have reserved directions, branches and loops.
 They mostly have thread like structures

9. Spread
 Spread by direct contact with blood or other fluids of
an infected human or other animal

10. Transmission

11. Symptoms

12. Late symptoms

13. How it gets into our systems?
 There are two candidates for host cell entry proteins:
 Cholestrol transport protein
 Macophages: the immune cell receptors

16. Epidemology
 The disease tipicaly occurs in tropical regions of Sub-
Saharan Africa.
 From 1976 to 2013, WHO reported 1,716 confirm cases.
 As of 16 Dec,2014 6,756 deaths are reported.

18. Zaire outbreak
 On 26 August,1976 outbreak of Ebola began in small
village.
 The first person infected with this disease was a village
school headmaster.

19. 2013-2014 West Africa Outbreak

20. World wide outbreaks

21. Affected Parts

22. The expected reservoirs(Fruit bat)

23. Effects on animals (WILD animals)
 Ebola have resulted in deaths of 5,000 Gorillas
 Resulted in 88% decline in Chimpanzee

24. Domestic animals
 In 2012, it was demonstrated that it can travel without
contact with pigs.
 Scientists failed to achieve transmission factors in
animals.
 Dogs may become infected from this virus but not
develop symptoms.

25. Medications
 Balancing electrolytes in body
 Treat other infections in body
 Maintain blood pressure

26. Treatment
 Currently, there is no treatment for EVD and doctors
simply treat symptoms, support the infected person
and deal with any complications that result from the
disease.

27. Preventative Measures

28. Preventative Measures
 Avoid contact with infected bats, monkeys or apes.
 Avoid contact with raw bush meat. Bush meat is the
meat of wild animals; this includes hoofed animals,
rats, bats and monkeys.

29. Future Perspective
 The natural reservoirs or the hosting body for this
deadly creature is still unknown

30. Summary
 We have isolated a new strain of Ebola virus from a
non-fetal human case infected during the autopsy of a
wild Chimpanzee. The wild troop to which this animal
belonged has been decimated by outbreaks of
haemorrhagic syndromes. This is the first time that a
human infection has been connected to naturally-
infected monkeys in Africa. Data from the long term
survey of this troop of chimpanzee could answer
questions about the natural reservoirs of the Ebola
virus.

31. May Almighty keep us
away from such viruses.
Ameen