Ebola is a deadly disease currently infecting parts of Africa. The first outbreak occurred in 1976 in Sudan and the Democratic Republic of the Congo. Research is underway to develop vaccines and treatments for Ebola, including initial human testing of an investigational vaccine by the National Institutes of Health. Symptoms include fever, headache, muscle pain, and can include bleeding. Treatment involves isolation, supportive care, and experimental therapies are being tested. Prevention requires careful hygiene and avoiding contact with bats, primates, or materials contaminated with fluids from infected humans or animals.