This lecture is about NEURAL NETWORKS WITH “R”. Artificial Neural Networks (ANNs) that starting from the mechanisms regulating natural neural networks, plan to simulate human thinking. The discipline of ANN arose from the thought of mimicking the functioning of the same human brain that was trying to solve the problem. The Machine learning is a branch of AI which helps computers to program themselves based on the input data. In this regard, Machine learning gives AI the ability to do data-based problem solving. This lecture shows applications.