The document discusses team science approaches for conducting research. It describes multidisciplinary, interdisciplinary, and transdisciplinary approaches. Multidisciplinarity involves researchers from different fields working independently towards a common goal. Interdisciplinarity involves joint work but researchers retain their own perspectives. Transdisciplinarity uses an integrated conceptual framework combining theories from different fields. The author believes all approaches are needed for clinical and translational research but team composition depends on the research topic and design. Effective collaboration through hands-on projects helped the author gain knowledge to achieve research goals, but inappropriate transfer of lessons between initiatives poses a challenge.