Wicked problems are complex issues in health, environmental, and social domains that are difficult to solve due to their multifaceted nature, while transdisciplinary research (TDR) involves collaborative approaches across various disciplines to address these problems. TDR is essential for resolving complex issues as it brings together diverse perspectives and knowledge from multiple stakeholders, enhancing understanding and practical solutions. However, the unpredictable and multifactorial nature of wicked problems makes definitive resolutions challenging.