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DNA Trek Confidential 
Slide - 1 
Slide - ‹#› 
DNATREK develops traceability solutions to ensure the quality and safety of food, air and water resources 
Anthony Zografos, Ph.D 
azografos@dnatrek.com
Slide - ‹#› 
DNATraxTM: a versatile material 
Biodetection 
–Original Application 
–Developed by LLNL under DoD funding; 
–Pilot projects in progress 
–“Low hanging fruit” 
Food Traceability 
–Great fit to technology 
–Very small technical risk 
–Huge opportunity in a growing market
Slide - ‹#› 
1- Food Traceability: a huge opportunity 
Cost of foodborne illnesses in the US: >$70 billion/yr 
Cost of fraud to food industry: ~$15 billion/yr 
Inability to quickly resolve food safety problems 
–Frustrates the regulators 
–Burdens producers with undue recall costs 
–Tarnishes brands 
–Undermines the public’s faith in the safety of the food supply
Slide - ‹#› 
Traceability = Rapid Containment 
Source of 2011 cantaloupe listeria outbreak was identified (per FDA) in RECORD time: 10 days 
During that outbreak 
–33 deaths 
–150 hospitalizations 
–Hundreds of millions in recall costs 
–Cantaloupe industry has still not fully recovered
DNA Trek Confidential 
Slide - 5 
Slide - ‹#› 
DNATrax™ TRACE PRODUCE FROM FORK TO FARM IN MINUTES 
<1 hr 
4-6 weeks 
? 
? 
? 
?
Slide - ‹#› 
The DNATrax™ Food Tracer 
A safe and edible biological barcode 
–Easily applied to produce at the source 
Identifies in minutes product origin information down to field, crew, machine and date 
Enables detection of 
adulteration or fraud 
in minutes 
Italian Truffle: $1500/lb 
Chinese Truffle: $20/lb 
100 % λ? 
75 % λ?
Slide - ‹#› 
2 - Biodetection: Low hanging fruit 
The bar to produce biological weapons is very low and getting lower 
No safe way to in-situ test biodetection and filtration systems 
Biodefense readiness at stake
Slide - ‹#› 
The Solution: The DNATraxTM Biosimulant 
 Synthetic DNA with variable properties 
Challenges detection and filtration systems in place 
Safe for humans 
Can simulate multiple sources and multiple threats in a single test 
No clean up or decontamination necessary 
Already approved for releases 
Planned tests in NYC, SFO and Boston subways
Slide - ‹#› 
DNATrax release at the Pentagon 
	 
“…As a result we have been able to make marked performance 
improvements to the Pentagon’s biological detection system…” 
Deputy Director of PFPA
Slide - ‹#› 
Team 
Anthony Zografos, Ph.D - CEO 
–COO CPAC (healthcare) - LLNL licensed technology 
–Executive positions at four start-ups, Accuray, Applied Materials, KLA-Tencor 
–Ph.D Mechanical Engineering, MBA 
John Salony – Interim CFO 
–Consultant, RGP 
–VP, Merrill Lynch Investment Banking 
George Farquar, Ph.D 
–Inventor of DNATraxTM 
–Currently Senior Scientist at LLNL 
–Ph.D Physical Chemistry 
Catherine Elizondo 
–Business Development Executive at LLNL
Slide - ‹#› 
Advisory Board 
Jennifer McEntire, Ph.D 
–Chief Science Officer, The Acheson Group 
–Ran large pilot traceability program for FDA 
Prof. Fotis Sotiropoulos 
–Director, St. Anthony Falls Lab, Univ. of Minnesota 
–Expert in aerodynamics and environmental monitoring 
Garrett Patricio 
–VP Ops and General Counsel, Westside Produce 
–Cantaloupe Grower and Traceability Expert 
Producer, 3rd Party Food Safety Director (pending confirmation)
Slide - ‹#› 
Food Traceability a $14B Market 
Global Food Traceability Market: $14B by 2020 
Food marking technologies: $4B by 2017 
Key Market Drivers 
– Food Safety Modernization Act: requires traceability 
–Increasing routine tests by FDA 
–Legalization of marijuana 
–Consumer sensitivity to food origin 
–Major food fraud in China and India 
 High Risk and Premium: ~$1.4B 
Food Traceability: $14 B 
Product Marking: $4 B 
High Risk and Premium: $1.4B
Slide - ‹#› 
High 
✗ 
✗ 
✗ 
DNATraxTM the fastest food source tracer 
Harvestmark QR 
GS1 Lot Barcode 
RFID 
Speed of traceback 
Cost of implementation 
Applied to individual items 
Environmental flexibility 
DNATrax 
✗ 
✗ 
✔ 
✔ 
✔ 
$600K 
$10-15K 
1 hour 
10-30 days 
<1 hour 
High 
High 
$200K 
No 
No 
Yes 
Low 
✔ 
1-7 days 
No 
✔ 
✔ 
✗ 
≈ 
✗ 
✗ 
✔ 
$200K
Slide - ‹#› 
Biodetection a $5.6B Market 
Global biodetection market: $5.6B by 2017 
Test and Evaluation: ~$1B 
Market Drivers 
–Proliferation of “how-to” for bio- agent production 
–All US Navy ships equipped with biodetection networks by 2015 
–BioWatch Gen-3 cancellation 
U.S. “High Risk” segment (DoD, DoS): ~ 75M 
Global Biodetection: $5.6 B 
Test & Evaluation: $1 B 
U.S. High Risk: $75M
Slide - ‹#› 
✗ 
DNATraxTM the most versatile biosimulant 
Tagged BT 
Gas Tracers 
Indoor Use 
Tunable properties 
Cleanup needed 
Multiple sources, agents 
DNATrax 
✗ 
✔ 
✔ 
✔ 
✔ 
✗ 
✔ 
✗ 
≈ 
≈ 
✗ 
≈ 
Urea Particles 
≈ 
≈ 
✗
Slide - ‹#› 
Multiple Revenue Streams 
Biodefense Revenue Stream 
–Enrollment 
–Equipment (release, sampling, analysis) 
–Material Sales 
Food Traceability Revenue Stream: 
–Enrollment 
–Annual Subscriptions 
–Material Sales 
–Analytical Services, primers, probes for QA and investigations 
–Instruments (long term)
Slide - ‹#› 
Food Market Strategy - SafeTracesTM 
Secure FDA Support 
–Safety (approval as food additive) - done 
–Effectiveness (SBIR or other grant) – in progress 
–Promote institutional Use (DNATrax in routine tests) 
Innovators/Early Adopters 
–Premium goods(truffles, olive oil, etc.); prevent adulteration, branding 
–Large producers of high risk foods with good safety records: defend reputation, manage recalls 
Partnership with Intertek Food Services – IFMS* 
*Integrated Food Management System
Slide - ‹#› 
FDA Support 
Inclusion of DNATrax in the routine FDA tests will be a key adoption driver
Slide - ‹#› 
Biodefense Market Strategy - DNATraxTM 
Leverage LLNL ties into defense community 
–Participate in 2015 subway tests – first material sale 
–Pilot programs ( SBIR or other government grant) 
Become biosimulant of record for US Navy 
On-going advocacy to promote adoption 
 TECMIPT* Membership 
–Recommends T&E standards across all DoD 
*Test and Evaluation Capabilities and Methodologies Integrated Process Team
Slide - ‹#› 
Financial Projections 
Please contact company for detailed financial projections
Slide - ‹#› 
Capital Raise 
$ 1 million convertible note 
Use of Funds 
–Complete food additive registration (U.S., E.U.) 
–Pilot program for 4-5 classes of produce 
–Set up DNATrax pilot production 
–Develop strategic partnerships
Slide - ‹#› 
Future Raises 
$1 million in 2016 
–Exit Driver: Navy adoption 
$3-$4 million in 2017 
–Exit Driver: FDA “endorsement”
Slide - ‹#› 
Exit Scenarios 
Biodefense (Northrop-Grumman) 
AgTech (Monsanto, Syngenta, DuPont, etc.) 
Life Sciences (BioRad, Life Technologies, Cepheid, etc.)
Slide - ‹#› 
Contact Information 
Anthony Zografos, Ph.D 
Founder and CEO 
azografos@dnatrek.com 
510-761-6782

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DnaTrek presentation at LLNL

  • 1. DNA Trek Confidential Slide - 1 Slide - ‹#› DNATREK develops traceability solutions to ensure the quality and safety of food, air and water resources Anthony Zografos, Ph.D azografos@dnatrek.com
  • 2. Slide - ‹#› DNATraxTM: a versatile material Biodetection –Original Application –Developed by LLNL under DoD funding; –Pilot projects in progress –“Low hanging fruit” Food Traceability –Great fit to technology –Very small technical risk –Huge opportunity in a growing market
  • 3. Slide - ‹#› 1- Food Traceability: a huge opportunity Cost of foodborne illnesses in the US: >$70 billion/yr Cost of fraud to food industry: ~$15 billion/yr Inability to quickly resolve food safety problems –Frustrates the regulators –Burdens producers with undue recall costs –Tarnishes brands –Undermines the public’s faith in the safety of the food supply
  • 4. Slide - ‹#› Traceability = Rapid Containment Source of 2011 cantaloupe listeria outbreak was identified (per FDA) in RECORD time: 10 days During that outbreak –33 deaths –150 hospitalizations –Hundreds of millions in recall costs –Cantaloupe industry has still not fully recovered
  • 5. DNA Trek Confidential Slide - 5 Slide - ‹#› DNATrax™ TRACE PRODUCE FROM FORK TO FARM IN MINUTES <1 hr 4-6 weeks ? ? ? ?
  • 6. Slide - ‹#› The DNATrax™ Food Tracer A safe and edible biological barcode –Easily applied to produce at the source Identifies in minutes product origin information down to field, crew, machine and date Enables detection of adulteration or fraud in minutes Italian Truffle: $1500/lb Chinese Truffle: $20/lb 100 % λ? 75 % λ?
  • 7. Slide - ‹#› 2 - Biodetection: Low hanging fruit The bar to produce biological weapons is very low and getting lower No safe way to in-situ test biodetection and filtration systems Biodefense readiness at stake
  • 8. Slide - ‹#› The Solution: The DNATraxTM Biosimulant  Synthetic DNA with variable properties Challenges detection and filtration systems in place Safe for humans Can simulate multiple sources and multiple threats in a single test No clean up or decontamination necessary Already approved for releases Planned tests in NYC, SFO and Boston subways
  • 9. Slide - ‹#› DNATrax release at the Pentagon “…As a result we have been able to make marked performance improvements to the Pentagon’s biological detection system…” Deputy Director of PFPA
  • 10. Slide - ‹#› Team Anthony Zografos, Ph.D - CEO –COO CPAC (healthcare) - LLNL licensed technology –Executive positions at four start-ups, Accuray, Applied Materials, KLA-Tencor –Ph.D Mechanical Engineering, MBA John Salony – Interim CFO –Consultant, RGP –VP, Merrill Lynch Investment Banking George Farquar, Ph.D –Inventor of DNATraxTM –Currently Senior Scientist at LLNL –Ph.D Physical Chemistry Catherine Elizondo –Business Development Executive at LLNL
  • 11. Slide - ‹#› Advisory Board Jennifer McEntire, Ph.D –Chief Science Officer, The Acheson Group –Ran large pilot traceability program for FDA Prof. Fotis Sotiropoulos –Director, St. Anthony Falls Lab, Univ. of Minnesota –Expert in aerodynamics and environmental monitoring Garrett Patricio –VP Ops and General Counsel, Westside Produce –Cantaloupe Grower and Traceability Expert Producer, 3rd Party Food Safety Director (pending confirmation)
  • 12. Slide - ‹#› Food Traceability a $14B Market Global Food Traceability Market: $14B by 2020 Food marking technologies: $4B by 2017 Key Market Drivers – Food Safety Modernization Act: requires traceability –Increasing routine tests by FDA –Legalization of marijuana –Consumer sensitivity to food origin –Major food fraud in China and India  High Risk and Premium: ~$1.4B Food Traceability: $14 B Product Marking: $4 B High Risk and Premium: $1.4B
  • 13. Slide - ‹#› High ✗ ✗ ✗ DNATraxTM the fastest food source tracer Harvestmark QR GS1 Lot Barcode RFID Speed of traceback Cost of implementation Applied to individual items Environmental flexibility DNATrax ✗ ✗ ✔ ✔ ✔ $600K $10-15K 1 hour 10-30 days <1 hour High High $200K No No Yes Low ✔ 1-7 days No ✔ ✔ ✗ ≈ ✗ ✗ ✔ $200K
  • 14. Slide - ‹#› Biodetection a $5.6B Market Global biodetection market: $5.6B by 2017 Test and Evaluation: ~$1B Market Drivers –Proliferation of “how-to” for bio- agent production –All US Navy ships equipped with biodetection networks by 2015 –BioWatch Gen-3 cancellation U.S. “High Risk” segment (DoD, DoS): ~ 75M Global Biodetection: $5.6 B Test & Evaluation: $1 B U.S. High Risk: $75M
  • 15. Slide - ‹#› ✗ DNATraxTM the most versatile biosimulant Tagged BT Gas Tracers Indoor Use Tunable properties Cleanup needed Multiple sources, agents DNATrax ✗ ✔ ✔ ✔ ✔ ✗ ✔ ✗ ≈ ≈ ✗ ≈ Urea Particles ≈ ≈ ✗
  • 16. Slide - ‹#› Multiple Revenue Streams Biodefense Revenue Stream –Enrollment –Equipment (release, sampling, analysis) –Material Sales Food Traceability Revenue Stream: –Enrollment –Annual Subscriptions –Material Sales –Analytical Services, primers, probes for QA and investigations –Instruments (long term)
  • 17. Slide - ‹#› Food Market Strategy - SafeTracesTM Secure FDA Support –Safety (approval as food additive) - done –Effectiveness (SBIR or other grant) – in progress –Promote institutional Use (DNATrax in routine tests) Innovators/Early Adopters –Premium goods(truffles, olive oil, etc.); prevent adulteration, branding –Large producers of high risk foods with good safety records: defend reputation, manage recalls Partnership with Intertek Food Services – IFMS* *Integrated Food Management System
  • 18. Slide - ‹#› FDA Support Inclusion of DNATrax in the routine FDA tests will be a key adoption driver
  • 19. Slide - ‹#› Biodefense Market Strategy - DNATraxTM Leverage LLNL ties into defense community –Participate in 2015 subway tests – first material sale –Pilot programs ( SBIR or other government grant) Become biosimulant of record for US Navy On-going advocacy to promote adoption  TECMIPT* Membership –Recommends T&E standards across all DoD *Test and Evaluation Capabilities and Methodologies Integrated Process Team
  • 20. Slide - ‹#› Financial Projections Please contact company for detailed financial projections
  • 21. Slide - ‹#› Capital Raise $ 1 million convertible note Use of Funds –Complete food additive registration (U.S., E.U.) –Pilot program for 4-5 classes of produce –Set up DNATrax pilot production –Develop strategic partnerships
  • 22. Slide - ‹#› Future Raises $1 million in 2016 –Exit Driver: Navy adoption $3-$4 million in 2017 –Exit Driver: FDA “endorsement”
  • 23. Slide - ‹#› Exit Scenarios Biodefense (Northrop-Grumman) AgTech (Monsanto, Syngenta, DuPont, etc.) Life Sciences (BioRad, Life Technologies, Cepheid, etc.)
  • 24. Slide - ‹#› Contact Information Anthony Zografos, Ph.D Founder and CEO azografos@dnatrek.com 510-761-6782