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FOOD
MECHANICAL &
ENZYMATIC BREAKDOWN
ABSORBTION
NUTRITON
COMSUMPTION OF HEATHY ADULT :
SOLID : 1 KG
LIQUID : 1 TO 2 L
DIGESTIVE SYSTEM
GASTRO INTESTINAL
TRACT/ALIMENTARTY
CANAL
PRIMARY DIGESTIVE
ORGANS
ACCESSORY DIGESTIVE
ORGANS
GI TRACT :
• TUBULAR
STRUCTURE
• FROM MOUTH
TO ANUS
• 30 FEET
PRIMARY
DIGESTIVE
ORGANS
• MOUTH
• PHARNYX
• ESOPHAGUS
• STOMACH
• SMALL INTESTINE
• LARGE INTESTINE
ACCESSORY
DIGESTIVE
ORGANS
• TEETH
• TONGUE
• SALIVARY GLANDS
• EXOCRINE PART OF PANCREAS
• LIVER
• GALL BLADDER
FUNCTION :
CARRY OUT
ACTUAL
DIGESTION
FUNCTION :
HELP PRIMARY
DIGESTIVE
ORGANS
G.I.
TRACT
FUNCTIONS
OF
DIGESTIVE
ORGANS
4 LAYERS
• MUCUS LAYER
• SUBMUCUS LAYER
• MUSCULAR LAYER
• SEROUS/FIBROUS LAYER
INSIDE
OUTSIDE
LAYERS OF
G.I.TRACT
1
MUCUS
LAYER
 INNERMOST LAYER.
 ALSO CALLED
GASTROINTESTINAL
MUCOSA/MUCUS.
 FACES THE G.I. TRACT
3 LAYERS :
1. EPITHILIAL
LINING
2. LAMINA
PROPRIA
3. MUSCULARIS
MUCOSA
• IS IN CONTACT WITH THE CONTENTS OF G.I. TRACT
• TYPE OF CELLS VARIES IN DIFFERENT PARTS :
1. INNER SURFACE OF MOUTH, SURFACE OF TONGUE,
INNER SURFACE OF PHARNYX AND ESOPHAGUS =
STRATIFIED SQUAMOUS EPITHELIAL CELLS.
2. STOMACH, SMALL INTESTINE AND LARGE INTESTINE =
COLUMNAR EPITHELIAL CAELLS.
• FORMED BY CONNECTIVE TISSUES
CONTAINING FIBROBLASTS,
MACROPHAGEES, LYMPHOCYTES AND
EOSINOPHILS
• CONSISTS OF A THIN LAYER OF SMOOTH
MUSCLES FIBRES
• ABSENT IN = MOUTH AND PHARNYX
• PRESENT IN = ESOPHAGUS ONWARDS
EPITHELIA
L LINING
MUSCULAR
IS MUCOSA
LAMINA
PROPRIA
SUBMUCUS
LAYER
2
• PRESENT IN ALL PARTS OF G.I. TRACT
EXCEPT MOUTH AND PHARNYX
• CONTAINS LOOSE COLLAGEN FIBERS,
RETICULAR FIBERS AND FEW CELLS OF
CONNECTIVE TISSUE
• ALSO CONTAINS BLOOD VESSLES,
LYMPHATIC VESSELS AND NERVE
PLEXUS [MEISSNER PLEXUS]
--O--
MEISSNER
PLEXUS/
SUBMUCUS NERVE
PLEXUS
INTESTINAL
WALL WITH
INTRINSIC
NERVE
PLEXUS
MUSCLULAR
LAYER
3 • SKELETAL MUSCLE FIBRES :
LIPS, CHEEKS, WALL OF
PHARYNX
• SKELETAL AND SMOOTH
MUSCLES FIBRES : ESOPHAGUS
• SMOOTH MUSCLES FIBRES :
WALL OF STOMACH AND
INTESTINE
• AUERBACH PLEXUS : BETWEEN
CIRCULAR AND LONGITUDINAL
MUSCLE FIBRES
• INTERNAL ANAL SPHINCTER :
SMOOTH MUSCLE FIBRES
(INNER CIRCULAR LAYER OF
ANAL CANAL)
• EXTERNAL ANAL SPHINCTER :
SKELETAL MUSCLE FIBRES
SMOOTH
MUSCLE
FIBRES
INNER
LAYER
MIDDLE
LAYER
OUTER
LAYER
STOMACH OBLIQUE CIRCULAR LONGITU
DINAL
INTESTIN
E
CIRCULAR --- LONGITU
DINAL
SEROUS/
FIBROUS
LAYER
4
OUTERMOST LAYER OF G.I. TRACT
SEROUS LAYER/SEROSA FIBROUS LAYER/FIBROSA
CONTENT :
CONNECTIVE TISSUE,
MESOEPITHELIAL CELLS
LOCATION :
STOMACH,
SMALL INTESTINE,
LARGE INTESTINE
CONTENT :
CONNECTIVE TISSUE
LOCATION :
PHARYNX,
ESOPHAGUS
NERVE SUPPLY
INTRINSIC
PLEXUS
AUERBACH
PLEXUS
MEISSNER
PLEXUS
EXTRINSIC
AUTONOMIC
NERVOUS
SYSTEM
SYMPATHETIC
PARASYMPATHETIC
FORMS
ENTERIC
NERVOUS
SYSTEM
CONTROLS
THE
ENTERIC
NERVOUS
SYSTEM
• PRESENT WITHIN THE WALL OF THE G.I. TRACT
(FROM OESOPHAGUS TO ANUS)
• CONTROLS ALL THE SECRETION AND MOVEMENTS OF
G.I. TRACT
• NETWORK OF NERVE FIBRES ARE CALLED PLEXUS,IN
THIS SYSTEM THERE ARE TWO MAJOR PLEXUS :
1. AUERBACH PLEXUS
2. MEISSNER PLEXUS
• THESE NERVES PLEXUS CONTAIN NERVE CELL BODIES,
PROCESSE OF NERVE CELLS AND THE RECEPTORS
• G.I. TRACT HAVE STRECTH AND CHEMO RECEPTORS
• THE ENTERIC NERVOUS SYSTEM IS KNOWN AS THE “SECOND
BRAIN”
• IT CAN OPERATE INDEPENDENTLY OF THE BRAIN AND SPINAL
CORD, THE CENTRAL NERVOUS SYSTEM
• IT HAS ALSO BEEN CALLED THE ‘FIRST BRAIN’ BASED ON
EVIDENCE SUGGESTING THAT THE ENS EVOLVED BEOFRE THE
CNS
AUERBACH
PLEXUS
• LOCATION :
BETWEEN INNER CIRCULAR MUSCLE AND OUTER
LONGITUDINAL MUSCLE
• FUNCTION :
REGULATE MOVEMENTS OF G.I. TRACT
ACCELERATE BY EXCITATORY
NEUROTRANSMITTER:
ACETYLCHOLINE,
SEROTONIN, SUBSTANCE P,ETC.
INHIBIT BY INHIBITORY
NEUROTRANSMITTER:
VASOACTIVE INTESTINAL PEPTIDE(VIP),
NEUROTENSIN, ENKEPHALIN,ETC. MYENTRIC
PLEXUS
MEISSNER
PLEXUS
• LOCATION:
BETWEEN MUSCULAR LAYER AND
SUBMUSCOSAL LAYER
• FUNCTIONS:
1.REGULATE SECRETIONS
2.NERVE FIBRE CAUSE CONSTRICTION OF
BLOOD VESSELS
SUBMUCOSAL
PLEXUS
• CONTROLS THE ENTERIC
NERVOUS SYSTEM
• BOTH SYMPATHETIC AND
PARASYMPATHETIC DIVISIONS OF
AUTONOMIC NERVOUS SYSTEM
INNERVATE THE G.I. TRACT
EXTRINSIC
NERVE
SUPPLY
TO
G.I.
TRACT
SYMPATHETIC
NERVE
FIBRES
PARTS OF G.I. TRACT
POST GANGLIONIC FIBRE
CELIAC AND MESENTRIC GANGLIA
PREGANGLIONIC FIBRE
LETERAL HORN OF SPINAL CORD (T5 TO L2)
FUNCTION:
• INHIBIT THE MOVEMENT AND DECREASE THE SECRETION BY SECRETING
NEUROTRANSMITTER NONADRENALINE
• CAUSES CONTRACTIONS OF SPHINCTERS
--O--
CELIAC:
ESOPHAGUS,
STOMACH,S.I.
MESENTRIC:
L.I.
PARTS OF G.I. TRACT
POST GANGLIONIC FIBRE
SYNAPSE (WITH POSTGANGLIONIC IN BOTH PLEXUS)
PREGANGLIONIC FIBRE
LETERAL HORN OF SPINAL CORD (C & S 1,2,3)
FUNCTION:
• ACCELERATE THE MOVEMENT AND INCREASE THE SECRETION BY
SECRETING NEUROTRANSMITTER ACETYLCHOLINE
• CAUSES DILATION OF SPHINCTERS
PARASYMPATHETIC
NERVE FIBRES
PREGANGLIONIC PARASYMPATHETIC NERVE FIBRES TRAVEL TO
THE ORGANS WITH THE HELP OF FOLLOWING NERVES:
CRANIAL NERVES:
• GLOSSOPHARYNGEAL NERVE(9TH):
MOUTH AND SALIVAERY GLANDS
• VAGUS NERVE(10TH):
ESOPHAGUS, STOMACH, SMALL INTESTINE
AND UPPER PART OF LARGE INTESTINE
SACRAL NERVE:
• PELVIC NERVE:
LOWER PART OF LARGE INTESTINE
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Digestive system introduction

  • 1.
  • 2. FOOD MECHANICAL & ENZYMATIC BREAKDOWN ABSORBTION NUTRITON COMSUMPTION OF HEATHY ADULT : SOLID : 1 KG LIQUID : 1 TO 2 L
  • 3.
  • 4. DIGESTIVE SYSTEM GASTRO INTESTINAL TRACT/ALIMENTARTY CANAL PRIMARY DIGESTIVE ORGANS ACCESSORY DIGESTIVE ORGANS GI TRACT : • TUBULAR STRUCTURE • FROM MOUTH TO ANUS • 30 FEET
  • 5. PRIMARY DIGESTIVE ORGANS • MOUTH • PHARNYX • ESOPHAGUS • STOMACH • SMALL INTESTINE • LARGE INTESTINE ACCESSORY DIGESTIVE ORGANS • TEETH • TONGUE • SALIVARY GLANDS • EXOCRINE PART OF PANCREAS • LIVER • GALL BLADDER FUNCTION : CARRY OUT ACTUAL DIGESTION FUNCTION : HELP PRIMARY DIGESTIVE ORGANS
  • 8. 4 LAYERS • MUCUS LAYER • SUBMUCUS LAYER • MUSCULAR LAYER • SEROUS/FIBROUS LAYER INSIDE OUTSIDE
  • 10. 1 MUCUS LAYER  INNERMOST LAYER.  ALSO CALLED GASTROINTESTINAL MUCOSA/MUCUS.  FACES THE G.I. TRACT 3 LAYERS : 1. EPITHILIAL LINING 2. LAMINA PROPRIA 3. MUSCULARIS MUCOSA
  • 11. • IS IN CONTACT WITH THE CONTENTS OF G.I. TRACT • TYPE OF CELLS VARIES IN DIFFERENT PARTS : 1. INNER SURFACE OF MOUTH, SURFACE OF TONGUE, INNER SURFACE OF PHARNYX AND ESOPHAGUS = STRATIFIED SQUAMOUS EPITHELIAL CELLS. 2. STOMACH, SMALL INTESTINE AND LARGE INTESTINE = COLUMNAR EPITHELIAL CAELLS. • FORMED BY CONNECTIVE TISSUES CONTAINING FIBROBLASTS, MACROPHAGEES, LYMPHOCYTES AND EOSINOPHILS • CONSISTS OF A THIN LAYER OF SMOOTH MUSCLES FIBRES • ABSENT IN = MOUTH AND PHARNYX • PRESENT IN = ESOPHAGUS ONWARDS EPITHELIA L LINING MUSCULAR IS MUCOSA LAMINA PROPRIA
  • 12. SUBMUCUS LAYER 2 • PRESENT IN ALL PARTS OF G.I. TRACT EXCEPT MOUTH AND PHARNYX • CONTAINS LOOSE COLLAGEN FIBERS, RETICULAR FIBERS AND FEW CELLS OF CONNECTIVE TISSUE • ALSO CONTAINS BLOOD VESSLES, LYMPHATIC VESSELS AND NERVE PLEXUS [MEISSNER PLEXUS] --O-- MEISSNER PLEXUS/ SUBMUCUS NERVE PLEXUS
  • 14. MUSCLULAR LAYER 3 • SKELETAL MUSCLE FIBRES : LIPS, CHEEKS, WALL OF PHARYNX • SKELETAL AND SMOOTH MUSCLES FIBRES : ESOPHAGUS • SMOOTH MUSCLES FIBRES : WALL OF STOMACH AND INTESTINE • AUERBACH PLEXUS : BETWEEN CIRCULAR AND LONGITUDINAL MUSCLE FIBRES • INTERNAL ANAL SPHINCTER : SMOOTH MUSCLE FIBRES (INNER CIRCULAR LAYER OF ANAL CANAL) • EXTERNAL ANAL SPHINCTER : SKELETAL MUSCLE FIBRES SMOOTH MUSCLE FIBRES INNER LAYER MIDDLE LAYER OUTER LAYER STOMACH OBLIQUE CIRCULAR LONGITU DINAL INTESTIN E CIRCULAR --- LONGITU DINAL
  • 15. SEROUS/ FIBROUS LAYER 4 OUTERMOST LAYER OF G.I. TRACT SEROUS LAYER/SEROSA FIBROUS LAYER/FIBROSA CONTENT : CONNECTIVE TISSUE, MESOEPITHELIAL CELLS LOCATION : STOMACH, SMALL INTESTINE, LARGE INTESTINE CONTENT : CONNECTIVE TISSUE LOCATION : PHARYNX, ESOPHAGUS
  • 17. • PRESENT WITHIN THE WALL OF THE G.I. TRACT (FROM OESOPHAGUS TO ANUS) • CONTROLS ALL THE SECRETION AND MOVEMENTS OF G.I. TRACT • NETWORK OF NERVE FIBRES ARE CALLED PLEXUS,IN THIS SYSTEM THERE ARE TWO MAJOR PLEXUS : 1. AUERBACH PLEXUS 2. MEISSNER PLEXUS • THESE NERVES PLEXUS CONTAIN NERVE CELL BODIES, PROCESSE OF NERVE CELLS AND THE RECEPTORS • G.I. TRACT HAVE STRECTH AND CHEMO RECEPTORS
  • 18. • THE ENTERIC NERVOUS SYSTEM IS KNOWN AS THE “SECOND BRAIN” • IT CAN OPERATE INDEPENDENTLY OF THE BRAIN AND SPINAL CORD, THE CENTRAL NERVOUS SYSTEM • IT HAS ALSO BEEN CALLED THE ‘FIRST BRAIN’ BASED ON EVIDENCE SUGGESTING THAT THE ENS EVOLVED BEOFRE THE CNS
  • 19. AUERBACH PLEXUS • LOCATION : BETWEEN INNER CIRCULAR MUSCLE AND OUTER LONGITUDINAL MUSCLE • FUNCTION : REGULATE MOVEMENTS OF G.I. TRACT ACCELERATE BY EXCITATORY NEUROTRANSMITTER: ACETYLCHOLINE, SEROTONIN, SUBSTANCE P,ETC. INHIBIT BY INHIBITORY NEUROTRANSMITTER: VASOACTIVE INTESTINAL PEPTIDE(VIP), NEUROTENSIN, ENKEPHALIN,ETC. MYENTRIC PLEXUS
  • 20. MEISSNER PLEXUS • LOCATION: BETWEEN MUSCULAR LAYER AND SUBMUSCOSAL LAYER • FUNCTIONS: 1.REGULATE SECRETIONS 2.NERVE FIBRE CAUSE CONSTRICTION OF BLOOD VESSELS SUBMUCOSAL PLEXUS
  • 21. • CONTROLS THE ENTERIC NERVOUS SYSTEM • BOTH SYMPATHETIC AND PARASYMPATHETIC DIVISIONS OF AUTONOMIC NERVOUS SYSTEM INNERVATE THE G.I. TRACT
  • 23. SYMPATHETIC NERVE FIBRES PARTS OF G.I. TRACT POST GANGLIONIC FIBRE CELIAC AND MESENTRIC GANGLIA PREGANGLIONIC FIBRE LETERAL HORN OF SPINAL CORD (T5 TO L2) FUNCTION: • INHIBIT THE MOVEMENT AND DECREASE THE SECRETION BY SECRETING NEUROTRANSMITTER NONADRENALINE • CAUSES CONTRACTIONS OF SPHINCTERS --O-- CELIAC: ESOPHAGUS, STOMACH,S.I. MESENTRIC: L.I.
  • 24. PARTS OF G.I. TRACT POST GANGLIONIC FIBRE SYNAPSE (WITH POSTGANGLIONIC IN BOTH PLEXUS) PREGANGLIONIC FIBRE LETERAL HORN OF SPINAL CORD (C & S 1,2,3) FUNCTION: • ACCELERATE THE MOVEMENT AND INCREASE THE SECRETION BY SECRETING NEUROTRANSMITTER ACETYLCHOLINE • CAUSES DILATION OF SPHINCTERS PARASYMPATHETIC NERVE FIBRES
  • 25. PREGANGLIONIC PARASYMPATHETIC NERVE FIBRES TRAVEL TO THE ORGANS WITH THE HELP OF FOLLOWING NERVES: CRANIAL NERVES: • GLOSSOPHARYNGEAL NERVE(9TH): MOUTH AND SALIVAERY GLANDS • VAGUS NERVE(10TH): ESOPHAGUS, STOMACH, SMALL INTESTINE AND UPPER PART OF LARGE INTESTINE SACRAL NERVE: • PELVIC NERVE: LOWER PART OF LARGE INTESTINE