This document discusses developmentally supportive care for preterm infants in the NICU. It aims to improve outcomes by supporting brain development, motor skills, sensory systems and family involvement through careful handling, positioning, feeding practices and control of the neonatal environment. Key aspects of care include protecting sleep, minimizing pain and stress, developmental activities like feeding and skin care, family centered care, and providing appropriate light, sound, and a caring staff. This holistic approach can help preterm infants heal and develop normally.