This document provides an overview of Indegene's capabilities to support emerging biotech organizations across the product lifecycle from pre-launch to post-launch. It outlines Indegene's expertise in areas such as clinical development, regulatory affairs, medical affairs, safety, pricing and market access, marketing, and patient engagement. For each area, it summarizes the challenges faced by emerging biotechs, Indegene's relevant expertise and solutions, including proprietary technologies and platforms. The document emphasizes Indegene's flexible engagement models and ability to scale its capabilities as needed to meet commercialization outcomes for emerging biotech clients.

1. Development and Co-Commercialization
for Emerging Biotech organizations

2. © 2022 Indegene. All rights reserved. 2
We support emerging biotechs across the product lifecycle
Low
High
Med
Pre-Launch Launch Post-Launch
Patient ID & Trial
Enrollment Services
Regulatory
Affairs
Medical Affairs
& Medical
Information
Safety/PV
Pricing, Market
Access, Payers
(PRMA)
Field Force &
Training
AOR: Creative
& Content
Services
Commercial
Operations:
Analytics
Patient
Services/Hub
Brand Strategy
& Omnichannel
Marketing
Investment

3. © 2022 Indegene. All rights reserved. 3
Our capabilities can be scaled as needed to meet commercialization
outcomes
Capabilities
L-24 L-20 L-16 L-12 L-8 L-4 L4 L8 L12 L16 L20 L24
Medical Affairs,
Regulatory &
Pharmacovigilance
Pricing, Reimbursement
& Market Access
Marketing
(including Sales)
Commercial Operations
Pre-Launch (L-24 to L) Post Launch (L to L24)
Product Launch
Medical information strategy & setup
Medical communication & publication plan
Launch plan and SOPs/Guidelines KOL engagement planning
Setup toll free
number
Med info operations - Insight tracking and reporting
Inquiry management
Medical communication deliverables Ongoing medical communication support
Clinical trial case management Safety DB setup Monitoring, ICSR & risk management, aggregate reporting
MSL hiring & onboarding
Scientific platform
Reg setup Label lifecycle, variations, CMC, HA queries, compliance / audits, license.
Define regulatory sops
Access diagnostic evaluation (quarterly)
Landscape analysis Access valuation & contract guidelines
MCO payer qualitative research
Final pricing strategy assessment
Physician & payer research
Initial pricing strategy & guidelines
Develop brand guidelines
Campaign planning and creation Continue tactical creation & execution Campaign refresh
Assess market opportunity & landscape
Design brand analytics
HCP segmentation & targeting
Define KPIs
Deploy & optimize omnichannel
Define territories Launch field force
Brand strategic platform Tactical Plan
OPDP prep/submit brand materials
Hire field force
Consumer research
Setup Rx triage
Setup consumer portal & apps
Create consumer marketing materials
Ongoing co-pay eligibility and claims administration
Ongoing management and pharmacy distribution
Content production and refresh
Develop consumer strategy, segmentation &
positioning
Advocacy group awareness Advocacy group meetings
Payer pull-through announcements
KAM education/training plan Develop KAM training materials
Pharmacy research
Develop pharmacy dispensing
strategy/wholesale/trade assets
KOL education/training deck
Convention planning & asset development
Brand performance reporting, social media listening
Develop training Learning retention
POA/Training
Develop web & tech plan Deploy web & tech Manage websites and tech ecosystem
Access diagnostic evaluation
Develop commercial operating plan Ongoing management, delivery and cross-functional operation alignment

4. Clinical
Technology-led solutions that span across
the clinical R&D lifecycle including study
startup, conduct and closeout, driving clinical
development programs to faster decisions,
and predictable success
Challenges faced by emerging life sciences companies
Indegene’s Expertise
Faster study startup
Reduced risk of study failures
Reduced disclosure and submission time
40%
30%
20%
Indegene’s Solutions
• Patient Recruitment • Clinical Trial Disclosures • Medical Writing
• Clinical Data Management
Integrated platforms for
faster R&D insights
Hybrid model using digital
marketing and concierge
services
Accountability from trial
design to completion
Interdisciplinary team of
medical writers
Experience in various clinical
trial disclosure platforms
Robust infrastructure and
flexible engagement models
Increasing speed of patient
enrolment at an affordable
cost
Fighting competition for
patients, when there are
more trials than patients
Limited funds; most
solutions are made for big
pharma’s budgets
© 2022 Indegene. All rights reserved. 4

5. Challenges faced by emerging life sciences companies
Indegene’s Expertise
Indegene’s Solutions
• Label Lifecycle
Management
• Regulatory Intelligence and
Market Strategy
• Packaging Artwork
Management
• Regulatory Submissions
Management
Deep regulatory expertise
and life sciences
contextualized technologies
Standalone or end-to-end
services with 24/7 launch
coverage
Transformational platforms
to drive performance and
regulatory efficiencies
Large pool of trained in-
house talent
Proprietary technology that
alerts about updates in real-
time
Comprehensive insights
that help frame apt
regulatory strategy
More hands needed to
organize documents,
materials, and data
A single consultant cannot
accomplish all strategic
goals
Existing solutions for
Regulatory teams are not
cost friendly
Timeline and SOP compliance
Right-First-Time quality score
Regulatory documents authored
100%
> 99.5%
2000+
© 2022 Indegene. All rights reserved. 5
Regulatory
Technology-led regulatory innovation across
the product development lifecycle, right from
regulatory intelligence and planning, to
content authoring, submissions, and HA
feedback management, ensure compliance in
the laborious and dynamic regulatory
landscape

6. Challenges faced by emerging life sciences companies
Indegene’s Expertise
Indegene’s Solutions
• Material Review and
Compliance
• Medical Communication
and Publications
• Medical Science Liaisons
• Medical Information
Management
• Health Economics and
Outcomes Research
• Learning and Development
• HCP Contracting • Prior Authorization
Analytics
Proprietary platforms and
tools custom-built for
medical affairs
Experience of 40+ MLR
transformation projects, led
by industry veterans
Deep understanding of
important global market
regulations
Artificial intelligence driven
content creation; scale as
needed, and at low costs
World’s largest healthcare–
focused training provider
Qualified resource pool for
liaising with MSLs and
HCPs
Lack of a dedicated team;
Medical Affairs especially
needs scale
Integrating several areas of
expertise into a single
strategy
Poor customer
engagement across
multiple touchpoints
Faster time-to-market for assets
Compliance using automation
Therapy areas
20-60%
100%
25+
© 2022 Indegene. All rights reserved. 6
Medical Affairs
Customer-centric experiences with
advanced technology-driven solutions that
modernize medical affairs operations,
including content creation, MLR reviews,
medical information and communications, as
well as strategic initiatives around market
access and launch excellence

7. Challenges faced by emerging life sciences companies
Unavailability of solutions
that can start small and
scale with the business
Lack of personnel could
compromise reporting
process integrity
Evidence is not easily
accessible by decision
makers
Periodic safety reports
Reduction in manual efforts
Case accuracy quality
2,500+
~75%
>99%
Indegene’s Expertise
Proprietary platforms and
tools custom-built for safety
and pharmacovigilance
Platform for business users
to search, view, and review
centrally curated articles
Deep understanding of
global regulatory and safety
practices
Theme-based customized
reports and Insights
Proactive identification of
appropriate data sources
Automated signal detection
by integrating statistical and
non-statistical methods
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Safety
Safety-proof patient experiences with
effective monitoring, analysis, reporting, and
risk mitigation of adverse event signals
across the product life cycle while ensuring
persistent regulatory compliance
Indegene’s Solutions
• Aggregate Reports
Writing
• Literature and Social Media
Monitoring
• Signal Detection and
Management
• Risk Management

8. Challenges faced by emerging life sciences companies
Consistency and efficiency
are a problem when using
consultants
Data driven decisions are
hard to make due to
unavailability of insights
Experts are not available
easily and immediately;
lack of agility is a barrier
Person years of experience
in market access & pricing
Countries supported
Assets created
100+
20+
250+
Indegene’s Expertise
Indegene’s Solutions
• Landscape & Gap Analysis • Stakeholder Primary
Research – Payers, HCPs
and Patients
• Launch and In-market
Pricing Strategy
• Payer Segmentation,
Contracting Strategy and
Guidelines
• Market Opportunity/BD
Assessments
• Value Messaging,
Communication and
Budget Impact Modelling
SMEs with strong know-
how and successful track
record
Unique blend of domain
expertise and digital-first
approach
In-depth understanding of
access and payer
environment globally
>125 US and EU launch
price strategies completed
in the last 3 years
Wide experience; from large
disease states to oncology,
rare and gene therapies
Executive level support –
direct interactions and
retainers
© 2022 Indegene. All rights reserved. 8
Pricing,
Reimbursement and
Market Access
A unique blend of domain expertise and
next-gen digital capabilities to help shape
and execute the right pricing and market
access strategy for your products

9. Challenges faced by emerging life sciences companies
Need the agility of just-in-
time solutions to position
against competition
Need partners rather than
vendors who are flexible
with engagement models
Quality content and
communication comes with
a prohibitive cost
Cumulative years of senior leadership experience
Reduction in creative agency costs vs AORs
Faster speed to market with agile process
120+
50%
40%
Indegene’s Expertise
Indegene’s Solutions
• Brand Identity Design • Brand Strategy • Content Strategy
• Campaign & Content
Creation
• Omnichannel Planning &
Development
• Ongoing creative
Optimization
Comprehensive portfolio
with predefined content and
creative templates
End-to-end capabilities with
high in-house control to
create future ready brands
Proven expertise in brand
strategy planning, designing
creative digital assets
Unique POV from deep
customer insights
Scientific, medical, editorial
and graphical hygiene of
content through automation
Reduced burden on brand
teams managing multi-AOR
handoffs
© 2022 Indegene. All rights reserved. 9
Creative and Content
Creative strategies that cater to unique
customer journeys by understanding their
various touchpoints and reach customers
with relevant messages through receptive
communication channels

10. Challenges faced by emerging life sciences companies
How to engage HCPs at
scale when the field force
may not be effective
Marketing solutions to
supplement field force
exist, but costs are high
Need tools, resources and
capabilities which require
light infrastructure
Campaigns delivered worldwide
Brands engaged
Assets delivered globally across languages
5,000+
100+
900,000
Indegene’s Expertise
Indegene’s Solutions
Data & Analytics
• Market opportunity
assessment
• HCP universe and target
identification
• Data reports and dashboards
Omnichannel Tactics
• Campaign setup and
deployment
• Programmatic and social
media setup
• Adjust channel mix
Technology & Systems
• Infrastructure & ecosystem
audit
• Data architecture planning
• Platform deployment
AI driven model combined
with proprietary IP identifies
optimal channel mix for
HCPs
Codified best practices to
drive efficiencies at scale;
adapted from our 20+years
of Big Pharma experience
Leverage digital affinity, Rx
potential and market access
data to identify HCPs most
likely to Rx
© 2022 Indegene. All rights reserved. 10
Omnichannel HCP
Engagement
Scale commercial operations with adaptable
omnichannel content, comprehensive
campaign management, analytics and
technology expertise to create outstanding
customer experiences

11. Challenges faced by emerging life sciences companies
The MarTech universe in
healthcare was built for Big
Pharma’s deep wallets
Technology solutions need
to be scaled down for
Biotech’s needs
Need a compartmentalized
pricing model based on
what’s-needed-now
Indegene’s Expertise
Indegene’s Solutions
• MarTech Strategy Advisory • Technology
Implementation and
Management
• Web Infrastructure & Site
Enablement
Significantly faster time to
market for new web assets
through a template re-use
model
Created 1000 + new
websites for 80+ brands
including corporate, HCP,
brand, patient, and medical
portals
Self-serve interface with
drag and drop features
Out-of-the-box integrations
for marketing automation
and analytics
Brands engaged globally
New websites created
Time to deploy a full fledged website
200+
1000+
8 weeks
Centralized solution enables
standardization resulting in
reduction in costs and faster
time to market
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Web Services and
Technology
Purpose-built proprietary technology for
healthcare and life sciences, with a wide
range of third party/partner technologies to
drive efficiencies across the product lifecycle

12. Challenges faced by emerging life sciences companies
Insights across R&D
through Commercialization
are not easily available
To keep pace with evolving
commercial models, data
needs to be sourced
Need access to expert
POVs, and tools which can
help in decision making
Brands commercialized across product life cycle
Therapy areas and indications
Subject matter experts
200+
100+
400+
Indegene’s Expertise
Indegene’s Solutions
• Market Intelligence • Brand Performance • Sales Force Performance
• KOL Performance • Forecasting
Deep data literacy and
analytical know-how across
life sciences
Centre of Excellence
support spanning
organizations of all sizes
Strong data foundations to
build trust and transparency
Differentiated insights by
melding traditional sources
with contemporary data
Data science and ML
applications for complex use
cases
Leverage patient analytics
to enhance quality and
accuracy
© 2022 Indegene. All rights reserved. 12
Commercial
Operations – Data,
Analytics & AI
Data solutions, analytical models, cognitive,
and cloud capabilities for life sciences
organizations to maximize the value of data,
translate insights into actions, and unlock
new possibilities to drive business outcomes

13. Challenges faced by emerging life sciences companies
How to expand patient
reach and improve
experience at each step
Ensuring long-term
therapy adherence with
limited personnel
Reaching a wider patient
population across multiple
locations
Process adherence rate
Years of patient engagement expertise
Brands engaged
90%
11+
>35
Indegene’s Expertise
Indegene’s Solutions
• Patient App and Portal • Co-pay Operations • Direct to Pharmacy
Operations
• Patient CRM and App • Patient Education
Materials
Quickly deployable, HIPAA
and GDPR compliant
Physical plus digital; hybrid
engagement model
Expertise in patient privacy
and regulatory compliance
Single partner that offers an
entire ecosystem of
solutions
Strong digital edge across
the board with proprietary
technology
Proactive patient reach-outs
in the context of ‘care’
© 2022 Indegene. All rights reserved. 13
Patient
Engagement
Comprehensive solutions for patient
engagement, ranging from patient
identification and onboarding to continued
engagement for therapy adherence

14. With a legacy of over 20 years, we are your trusted partner
Ease of partnership, fully integrated
seamless delivery model
More than 100 brands, with
more experience than almost any
PharmaCo in the world
Indegene capabilities were built in the new world,
with cutting edge technology and artificial
intelligence to deliver better customer experience
A flexible pay for performance model that
minimizes initial investment allowing for
less dilution
Proven and demonstrated capability to drive
more Rx, with higher peak sales (compared
to PharmaCos or other vendors)
© 2022 Indegene. All rights reserved. 14

15. Thank You!