Success of any dental procedure is determined by a good isolation. Here is a seminar on how to isolate the oral cavity from fluids and maintain a good dry field while working on a patient
Success of any dental procedure is determined by a good isolation. Here is a seminar on how to isolate the oral cavity from fluids and maintain a good dry field while working on a patient
In this lecture I explain in step-by-step fashion the basics of Endodontic Diagnosis: Pulp Vitality Tests. a photo guide is attached to the guide to aid in better understanding of the topic
In this lecture I explain in step-by-step fashion the basics of Endodontic Diagnosis: Pulp Vitality Tests. a photo guide is attached to the guide to aid in better understanding of the topic
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
MIP 201T & MPH 202T
ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMS By - AKANKSHA ASHTANKAR
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
ABDOMINAL TRAUMA in pediatrics part one.drhasanrajab
Abdominal trauma in pediatrics refers to injuries or damage to the abdominal organs in children. It can occur due to various causes such as falls, motor vehicle accidents, sports-related injuries, and physical abuse. Children are more vulnerable to abdominal trauma due to their unique anatomical and physiological characteristics. Signs and symptoms include abdominal pain, tenderness, distension, vomiting, and signs of shock. Diagnosis involves physical examination, imaging studies, and laboratory tests. Management depends on the severity and may involve conservative treatment or surgical intervention. Prevention is crucial in reducing the incidence of abdominal trauma in children.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
1. Dr. Blend Ahmed Omer
M.SC. PERIODONTICS
Deposits on
The Teeth
1
DR. BLEND AHMED
Lecture 4
• LECTURER AT AL-KITAB UNIVERSITY - IRAQ
• LECTURER AT EPU-MEDICAL INST. KURDISTAN/IRAQ
2. Dental
Deposits
2
Any soft or hard substance attached to
tooth surfaces, often associated with
dental diseases such as:
• Caries or
• Periodontal disease
Example of Dental Deposits:
• Dental plaque or
• Dental calculus
DR. BLEND AHMED
3. Types of
Dental
Deposits
1. Acquired Pellicle
2. Materia Alba
3. Dental Plaque (Biofilm)
4. Dental Calculus (tartar)
5. Food Debris
3
1. Soft Deposits
2. Hard Deposits
DR. BLEND AHMED
4. 1. Acquired Pellicle
4
All surfaces in the oral cavity, including the hard and soft
tissues, are coated with a layer of organic material known as
the Acquired Pellicle.
• The pellicle on tooth surfaces consists of more
than 180 peptides, proteins, and glycoproteins.
❖ Consist of What?
❖ Contains:
• No Cells (Acellular)
• No Minerals
• No Bacteria
DR. BLEND AHMED
5. 5
2. Materia Alba
Is a soft white deposits (soft accumulations of bacteria and tissue cells) on
surfaces of the teeth but attachment occur on uncleaned tooth surface or
attach over dental plaque, that lack the organized structure of dental plaque.
Materia Alba differ from dental plaque by:
1. Its non organized structure.
2. Poorly attached to the tooth surfaces so water or air spray will remove it.
DR. BLEND AHMED
6. 6
its soft deposits which form the biofilm on hard surfaces.
Composition of Dental plaque:
1. Proliferating Microorganisms
2. Host Cells: (Macrophages, PMNL, Desquamated epithelial cells).
3. Intercellular matrix :(organic and inorganic contents)
4. Bacterial products and gingival fluid.
3. Dental Plaque/Biofilms
DR. BLEND AHMED
7. Sources of plaque nutrient:
1. Microbial symbiosis
2. Dead bacteria.
3. Lysed bacteria.
4. Saliva.
7
DR. BLEND AHMED
8. Retentive Factors for plaque Accumulation
1. Faulty restoration.
2. Caries.
3. Calculus.
4. Crowding.
5. Appliance (prosthodontic or orthodontic appliances)
8
DR. BLEND AHMED
9. 9
4. Phase FOUR (sequential adsorption of organisms).
Phases of Dental Plaque Development
1. Phase ONE (Molecular Adsorption):
Two days after stopping teeth cleaning, G +ve bacteria (rods and cocci) is more than G -ve bacteria.
2. Phase TWO (Single Organisms)
Three to Four days after stopping teeth cleaning, G-ve increase (fusobacterium nucleatum and
filamentous bacteria).
3. Phase THREE (Multiplication):
Five to Nine days after stopping teeth cleaning, G -ve increase more , spirilla and spirochetes that
mean more destruction of tissues.
DR. BLEND AHMED
Sequential adsorption of further bacteria to form a more complex and mature biofilm.
11. Classification of Dental Plaque
11
Supra gingival Plaque
1 Sub gingival Plaque
2
which is the marginal plaque and it cause gingivitis. occur under the gingiva with predilection for surface cracks,
defects ,roughness and over hanging margin of dental restoration.
DR. BLEND AHMED
12. Detection of Dental Plaque
12
1 2
By EYE By PROB
BUT some time small
area of plaque cannot
be detected by eye.
A probe by moving it along
gingival margin of tooth to see a
pin point plaque.
1 2 3 4
DR. BLEND AHMED
13. 13
Detection of Dental Plaque
3 4
By
DISCLOSING AGENT
By
FLUORESCENT DYE
Disclosing agents like disclosing tab. Fluorescent dye that give yellow color under
room light ,blue color under UV light.
DR. BLEND AHMED
14. 14
• It's hard deposits that form by mineralization of
dental plaque and is generally covered by a layer of
unmineralized plaque.
4. Dental Calculus
DR. BLEND AHMED
15. Classification of Dental Calculus
15
Supra gingival Calculus
1 Sub gingival Calculus
2
when present on the visible crown of teeth above
the gingival margin.
when present apically to the gingival margin in the
gingival sulcus.
DR. BLEND AHMED
16. 16
Composition of Dental Calculus
1. Hydroxyapatite
2. Magnesium whitlockite
3. Octa calcium phosphate
DR. BLEND AHMED
17. 17
1. Supra gingival calculus:
comprises yellow white deposits, however the color may change to brown as a result of secondary
staining from tobacco or food pigmentation. its follow the opening of major salivary gland.
2. Sub gingival calculus:
Is brown to black in color and often more hardly adherent to the tooth surface evenly distributed
on the various teeth ,but on the individual teeth its more prevalent on the a proximal and
lingual than on the buccal surface .
Clinical appearance of Dental Calculus
DR. BLEND AHMED
18. 18
2. Diagnoses of Sub gingival calculus:
Diagnosis of Dental Calculus
1. Diagnoses of Supra gingival calculus:
1. By clinical inspection when sufficient amount present.
2. Thin layer may be over looked by scraping or probing .
1. Indirectly diagnosed by its dark color shins through thin gingiva.
2. Detachment of the gingival margin from the tooth by air blast or by appropriate instrument .
3. Radiographic methods it may appear on a proximal surface.
4. The deep calculus is diagnosed by reflection of the gingival tissue during periodontal surgery.
DR. BLEND AHMED
19. 19
5. Food Debris
• Loose food particles collect about cervical third and proximal
embrasures of teeth.
• Food may forced between teeth during mastication in open contacts,
irregularities of occlusion and tooth mobility.
• Horizontal food impaction may occurs when interdental papillae are
reduced of missing.
• Self-cleansing through action of tongue, lips, and saliva may take place.
• Full debris removal can be done by tooth brushing, flossing and
using other aids .
DR. BLEND AHMED