dentifrice type formulation preparation packing

1. DENTIFRICE
Prepared by BABU CHAVDA
AKSHARPREET INSTITUTE OF
PHARMACY JAMNGAR

3. Function of dentifrice
Cleaning of tooth
Removal of stains
Minimize bed odour
Anti carries action
Mouth freshener
Polishing of teeth

4. TYPES
Cosmetic dentifrice
Therapeutic dentifrice

5. ABRASIVE AND POLISHING MATERIALS
Also call cleansing agents materials
It is main constituents of tooth paste or tooth
powder
Abrasive should have to be powder and hard but
not such that it makes scratches on the gum or
enamel
They are preferably water insoluble
It is responsible for removing food particle in
teeth and stains from teeth and amount of
abrasive is half of total weight of a tooth paste

6. the materials most widely used
are
Calcium carbonate
Tri calcium phosphate
Dicalcium phosphate
Aluminium phosphate

7. The cleaning action of the detergents is due to
their lowering of surface tension
They help in wetting and dispersion of powder
materials in the paste
They also help in producing foam
They help in removal of food particles and
removal of mucous
Sodium lauryl sulfates are use as detergents and
foaming agent

8. The substance that prevent drying of
toothpaste and maintains wetness and to
maintain consistency
The amount of humectants used normally can
vary from 5 to10 %
However sometimes higher amount of 30% or
more use
Actual amount is decided on specific gravity of
the powder mass
Glycerine sorbitol are use as humectants

9. Various hydrocolloids are used in toothpastes to
improve and maintain the consistency
They also prevent separation of pastes
Hydrocolloids are used In 1-2.5%
The amount of binding agent will depend on
the consistency
Carboxymethyl cellulose, sodium alginate ,
bentonite are use as binding aget

10. Sweetening agent is very important in
dentifrice
It is mainly used in order to mask the
other tastes
Sodium saccharine is widely use as
sweetening agent

11. Flavours are essentially to be
incorporated in dentifrice for long term in
the mouth
Also for leaving a pleasant and refreshing
smell in after use as a result the bad
odour in mouth is masked
Peppermint oil ,clove oil are use as
flavours

12. These are essentially required in
dentifrice as the product may be prone to
microbial growth due to the presence of
gums and water
Preservatives are normally dissolved and
the humectant and then mixed in other
components
Eg alcohol , formaldehyde glyceriness

13. COLOURS
They are not preferred much as
most of the tooth pastes are white
Nowadays several coloured
toothpastes are available to attract c
onsumer ‘s attention
EG Food colour

14. They are basically oxidising agents
Such as sodium perborate
hydrogen peroxide
Use as stain removal and whiteners
of teeth

15. These are sometimes
incorporated in tooth pastes to
facilitate the paste to come
out or filling purpose
Eg liquid paraffin

16. TOOTHPASTE
 mix glycerin and water add the solid
substances in it with stirring add flavor
and mix transfer in to suitable
container and store

18. Dentifrice are packed in flexible collapsible
tubes
Before tube are filled it self pass under blower
and vacuum to ensure cleanness
The tube is capped and the opposite end is
opened so the filling machine can load material
After ingredients are mix and tube are filled by
filling machine
Optical device rotates the tube

19.  Then the tube is filled by a descending pump
 After it is filled the end is sealed closed
 Then tubs gets code stamped on it indicating
where and when it was manufactured
 After tubes are filled they are inserted into
open paperboard boxes some companies do
this by hand
 The boxes are shipped in to warehouse and
stores