SlideShare a Scribd company logo
PRESENTED BY- Farazul Hoda
M.PHARM(PHARMACY PRACTICE)
2ND SEMESTER
• Dengue is a mosquito-borne, viral infection
transmitted by Aedes mosquitoes.
• The infection causes flu-like illness, and occasionally
develops into a potentially lethal complication called severe
dengue.
• Common name of the disease is ‘break-bone fever’ .
HISTORY
• Epidemics of an illness resembling dengue occurred in
1779, 1780 in three continents- Asia, Africa and North
America.
• First epidemic of DHF occurred in Manila, Philippines
1950.
• In India dengue virus was first isolated in Calcutta in 1945.
• Epidemic of Dengue hemorrhagic fever(DHF) first
occurred in Calcutta in 1963.
It is caused by a virus (Dengue Virus) Four different types
(Type 1,2,3,4)
AGE & SEX GROUPS AFFECTED
• All age groups & both sexes are affected
• Children > Adults
• Female > Male (severe)
• Deaths are more in children during DHF outbreak
• Immune status
Disease occurs more frequently in the rainy season
and immediately afterwards (July to October) in
India.
• Fever: continuous for 3 to 7 days
• Severe headache
• Joint pain, muscle pain, pain behind eyeballs
•Nausea, vomiting, and rash
• In very rare cases, the condition may worsen into
dengue haemorrhagic fever, leading to internal bleeding,
shock, or even death.
•Blood pressure
•Evidence of bleeding in skin or other sites
•Hydration status
•Evidence of increased vascular permeability-
pleural effusions, ascites
•Tourniquet test
Clinical laboratory tests
• CBC--WBC, platelets, hematocrit
• Albumin
• Liver function tests
• Urine--check for microscopic hematuria
 Dengue-specific tests
• Virus isolation
• Serology
• Antigen
• Antibody: IgM,IgG
•At present, no specific drug that can treat dengue
fever effectively.
• Patient should be isolated in a mosquito-free
environment to prevent the spread of disease.
•Fluids
• Rest
• Antipyretics (avoid aspirin and nonsteroidal anti-
inflammatory drugs)
• Monitor blood pressure, hematocrit, platelet count, level
of consciousness
• No licensed vaccine at present
• Recently Tetravalent Dengue Vaccine phase 3
trial completed in Asia.
The first dengue vaccine, Dengvaxia® (CYD-TDV) developed by Sanofi Pasteur was licensed
in December 2015 and has now been approved by regulatory authorities in 20 countries
for use in endemic areas in persons ranging from 9-45 years of age.
In April 2016, WHO issued a conditional recommendation on the use of the vaccine for
areas in which dengue is highly endemic as defined by seroprevalence of 70% or higher.
In November 2017, the results of an additional analysis to retrospectively determine
serostatus at the time of vaccination were released. The analysis showed that the subset
of trial participants who were inferred to be seronegative at time of first vaccination had a
higher risk of more severe dengue and hospitalizations from dengue compared to
unvaccinated participants.
Immunization
1.Rajapakse S, Rodrigo C, Rajapakse A. Treatment of dengue fever. Infection and
drug resistance. 2012;5:103.
2.Deen JL, Harris E, Wills B, Balmaseda A, Hammond SN, Rocha C, Dung NM,
Hung NT, Hien TT, Farrar JJ. The WHO dengue classification and case definitions:
time for a reassessment. The Lancet. 2006 Jul 8;368(9530):170-3.
3.Wiwanitkit V (July 2010). "Dengue fever: diagnosis and treatment". Expert
Review of Anti-Infective Therapy. 8 (7): 841–5
References
Dengue fever

More Related Content

What's hot

DENGUE CONTROL PROGRAMME-INDIA
DENGUE CONTROL PROGRAMME-INDIADENGUE CONTROL PROGRAMME-INDIA
DENGUE CONTROL PROGRAMME-INDIA
MAHESWARI JAIKUMAR
 
Lecture 9 dengue fever
Lecture 9 dengue feverLecture 9 dengue fever
Lecture 9 dengue fevercchaudoin87
 
EPIDEMIOLOGY OF DENGUE
EPIDEMIOLOGY OF DENGUEEPIDEMIOLOGY OF DENGUE
EPIDEMIOLOGY OF DENGUE
MAHESWARI JAIKUMAR
 
Dengue virus
Dengue virusDengue virus
Dengue virus
Creative-Diagnostics
 
Kontra Dengue Advocates presentation
Kontra Dengue Advocates presentationKontra Dengue Advocates presentation
Kontra Dengue Advocates presentation
Jake Pocz
 
Dengue
DengueDengue
Dengue
MisHanif
 
Prevention+of+dengue+fever eng
Prevention+of+dengue+fever engPrevention+of+dengue+fever eng
Prevention+of+dengue+fever engHoman Leung
 
Influenza: Symptoms, causes, treatment and prevention
Influenza: Symptoms, causes, treatment and preventionInfluenza: Symptoms, causes, treatment and prevention
Influenza: Symptoms, causes, treatment and prevention
Lazoi Lifecare Private Limited
 
Dengue in children
Dengue in childrenDengue in children
Dengue in childrenShama
 
Infleunza
InfleunzaInfleunza
update on Swine flu (H1N1)
update on Swine flu (H1N1)update on Swine flu (H1N1)
update on Swine flu (H1N1)
Shivshankar Badole
 
Chikungunia
ChikunguniaChikungunia
Chikungunia
Md.Shajaet Hossain
 
Best DENGUE Fever Treatment
 Best DENGUE Fever Treatment Best DENGUE Fever Treatment
Best DENGUE Fever Treatment
Surgerica
 
Dengue
DengueDengue
Dengue
Tina Yadav
 
DENGUE
DENGUE DENGUE
DENGUE
wasiuddin com
 
Ppt on anthrax and dengue fever
Ppt on anthrax and dengue feverPpt on anthrax and dengue fever
Ppt on anthrax and dengue fever
Mital Patel
 

What's hot (20)

DENGUE CONTROL PROGRAMME-INDIA
DENGUE CONTROL PROGRAMME-INDIADENGUE CONTROL PROGRAMME-INDIA
DENGUE CONTROL PROGRAMME-INDIA
 
Dengue fever
Dengue feverDengue fever
Dengue fever
 
Chikungunya PPT_RP
Chikungunya PPT_RPChikungunya PPT_RP
Chikungunya PPT_RP
 
Dengue presentation
Dengue presentationDengue presentation
Dengue presentation
 
Lecture 9 dengue fever
Lecture 9 dengue feverLecture 9 dengue fever
Lecture 9 dengue fever
 
Dengue mce 21_11_2012
Dengue mce 21_11_2012Dengue mce 21_11_2012
Dengue mce 21_11_2012
 
EPIDEMIOLOGY OF DENGUE
EPIDEMIOLOGY OF DENGUEEPIDEMIOLOGY OF DENGUE
EPIDEMIOLOGY OF DENGUE
 
Dengue virus
Dengue virusDengue virus
Dengue virus
 
Kontra Dengue Advocates presentation
Kontra Dengue Advocates presentationKontra Dengue Advocates presentation
Kontra Dengue Advocates presentation
 
Dengue
DengueDengue
Dengue
 
Prevention+of+dengue+fever eng
Prevention+of+dengue+fever engPrevention+of+dengue+fever eng
Prevention+of+dengue+fever eng
 
Influenza: Symptoms, causes, treatment and prevention
Influenza: Symptoms, causes, treatment and preventionInfluenza: Symptoms, causes, treatment and prevention
Influenza: Symptoms, causes, treatment and prevention
 
Dengue in children
Dengue in childrenDengue in children
Dengue in children
 
Infleunza
InfleunzaInfleunza
Infleunza
 
update on Swine flu (H1N1)
update on Swine flu (H1N1)update on Swine flu (H1N1)
update on Swine flu (H1N1)
 
Chikungunia
ChikunguniaChikungunia
Chikungunia
 
Best DENGUE Fever Treatment
 Best DENGUE Fever Treatment Best DENGUE Fever Treatment
Best DENGUE Fever Treatment
 
Dengue
DengueDengue
Dengue
 
DENGUE
DENGUE DENGUE
DENGUE
 
Ppt on anthrax and dengue fever
Ppt on anthrax and dengue feverPpt on anthrax and dengue fever
Ppt on anthrax and dengue fever
 

Similar to Dengue fever

Dengue, Malaria, Chikungunya, Japanese Encephalitis, Pest Control.pptx
Dengue, Malaria, Chikungunya, Japanese Encephalitis, Pest Control.pptxDengue, Malaria, Chikungunya, Japanese Encephalitis, Pest Control.pptx
Dengue, Malaria, Chikungunya, Japanese Encephalitis, Pest Control.pptx
YuvethaIndran
 
Dengue seminar prepared by sumel ashique,GNIPST
Dengue seminar prepared by sumel ashique,GNIPSTDengue seminar prepared by sumel ashique,GNIPST
Dengue seminar prepared by sumel ashique,GNIPST
sumel ashique
 
Dengue Hemorrhagic Fever- Case Study
Dengue Hemorrhagic Fever- Case StudyDengue Hemorrhagic Fever- Case Study
Dengue Hemorrhagic Fever- Case Study
Rozelle Mae Birador
 
Dengue
DengueDengue
Epidemiological Perspective of Influenza - Muskan.pptx
Epidemiological Perspective of Influenza - Muskan.pptxEpidemiological Perspective of Influenza - Muskan.pptx
Epidemiological Perspective of Influenza - Muskan.pptx
muskanpudasainee
 
Dengue Fever
Dengue FeverDengue Fever
Dengue Fever
MasudRana461
 
Dengue fever Epidemiology - pathogenesis - symptoms - diagnosis - Management ...
Dengue fever Epidemiology - pathogenesis - symptoms - diagnosis - Management ...Dengue fever Epidemiology - pathogenesis - symptoms - diagnosis - Management ...
Dengue fever Epidemiology - pathogenesis - symptoms - diagnosis - Management ...
Arun Vasireddy
 
DENGUE FEVER.pptx
DENGUE FEVER.pptxDENGUE FEVER.pptx
DENGUE FEVER.pptx
Dr Subodh Shah
 
Influenza, Bird Flu, SARS & Swine Flu.pptx
Influenza, Bird Flu, SARS & Swine Flu.pptxInfluenza, Bird Flu, SARS & Swine Flu.pptx
Influenza, Bird Flu, SARS & Swine Flu.pptx
Rahul Netragaonkar
 
Dengue.pptx
Dengue.pptxDengue.pptx
Dengue.pptx
KIMS
 
Dengue
DengueDengue
Diagnosis and management of dengue in children (IAP Infectious Diseases Chapter)
Diagnosis and management of dengue in children (IAP Infectious Diseases Chapter)Diagnosis and management of dengue in children (IAP Infectious Diseases Chapter)
Diagnosis and management of dengue in children (IAP Infectious Diseases Chapter)
Dr Padmesh Vadakepat
 
dengue.pptx
dengue.pptxdengue.pptx
dengue.pptx
Mittal Rathod
 
Dengue .pptx
Dengue .pptxDengue .pptx
Dengue .pptx
ExpertConsultClinic
 
Flu vaccine in Pregnanc An Overview Dr. Sharda Jain, Life Care Centre
Flu vaccine in Pregnanc An Overview Dr. Sharda Jain, Life Care Centre Flu vaccine in Pregnanc An Overview Dr. Sharda Jain, Life Care Centre
Flu vaccine in Pregnanc An Overview Dr. Sharda Jain, Life Care Centre Lifecare Centre
 
DENGUE.pptx
DENGUE.pptxDENGUE.pptx
Chikungunya
ChikungunyaChikungunya
Chikungunya
Upendra Raj Dhakal
 
DENGUE VIRUS
DENGUE VIRUSDENGUE VIRUS
DENGUE VIRUS
uroojumer1
 
Emerging infections dr rosni
Emerging infections dr rosniEmerging infections dr rosni
Emerging infections dr rosnimayazulkifli
 

Similar to Dengue fever (20)

Dengue, Malaria, Chikungunya, Japanese Encephalitis, Pest Control.pptx
Dengue, Malaria, Chikungunya, Japanese Encephalitis, Pest Control.pptxDengue, Malaria, Chikungunya, Japanese Encephalitis, Pest Control.pptx
Dengue, Malaria, Chikungunya, Japanese Encephalitis, Pest Control.pptx
 
Dengue seminar prepared by sumel ashique,GNIPST
Dengue seminar prepared by sumel ashique,GNIPSTDengue seminar prepared by sumel ashique,GNIPST
Dengue seminar prepared by sumel ashique,GNIPST
 
Dengue Hemorrhagic Fever- Case Study
Dengue Hemorrhagic Fever- Case StudyDengue Hemorrhagic Fever- Case Study
Dengue Hemorrhagic Fever- Case Study
 
Dengue
DengueDengue
Dengue
 
Epidemiological Perspective of Influenza - Muskan.pptx
Epidemiological Perspective of Influenza - Muskan.pptxEpidemiological Perspective of Influenza - Muskan.pptx
Epidemiological Perspective of Influenza - Muskan.pptx
 
Dengue fever update
Dengue fever update Dengue fever update
Dengue fever update
 
Dengue Fever
Dengue FeverDengue Fever
Dengue Fever
 
Dengue fever Epidemiology - pathogenesis - symptoms - diagnosis - Management ...
Dengue fever Epidemiology - pathogenesis - symptoms - diagnosis - Management ...Dengue fever Epidemiology - pathogenesis - symptoms - diagnosis - Management ...
Dengue fever Epidemiology - pathogenesis - symptoms - diagnosis - Management ...
 
DENGUE FEVER.pptx
DENGUE FEVER.pptxDENGUE FEVER.pptx
DENGUE FEVER.pptx
 
Influenza, Bird Flu, SARS & Swine Flu.pptx
Influenza, Bird Flu, SARS & Swine Flu.pptxInfluenza, Bird Flu, SARS & Swine Flu.pptx
Influenza, Bird Flu, SARS & Swine Flu.pptx
 
Dengue.pptx
Dengue.pptxDengue.pptx
Dengue.pptx
 
Dengue
DengueDengue
Dengue
 
Diagnosis and management of dengue in children (IAP Infectious Diseases Chapter)
Diagnosis and management of dengue in children (IAP Infectious Diseases Chapter)Diagnosis and management of dengue in children (IAP Infectious Diseases Chapter)
Diagnosis and management of dengue in children (IAP Infectious Diseases Chapter)
 
dengue.pptx
dengue.pptxdengue.pptx
dengue.pptx
 
Dengue .pptx
Dengue .pptxDengue .pptx
Dengue .pptx
 
Flu vaccine in Pregnanc An Overview Dr. Sharda Jain, Life Care Centre
Flu vaccine in Pregnanc An Overview Dr. Sharda Jain, Life Care Centre Flu vaccine in Pregnanc An Overview Dr. Sharda Jain, Life Care Centre
Flu vaccine in Pregnanc An Overview Dr. Sharda Jain, Life Care Centre
 
DENGUE.pptx
DENGUE.pptxDENGUE.pptx
DENGUE.pptx
 
Chikungunya
ChikungunyaChikungunya
Chikungunya
 
DENGUE VIRUS
DENGUE VIRUSDENGUE VIRUS
DENGUE VIRUS
 
Emerging infections dr rosni
Emerging infections dr rosniEmerging infections dr rosni
Emerging infections dr rosni
 

Recently uploaded

ACUTE SCROTUM.....pdf. ACUTE SCROTAL CONDITIOND
ACUTE SCROTUM.....pdf. ACUTE SCROTAL CONDITIONDACUTE SCROTUM.....pdf. ACUTE SCROTAL CONDITIOND
ACUTE SCROTUM.....pdf. ACUTE SCROTAL CONDITIOND
DR SETH JOTHAM
 
Are There Any Natural Remedies To Treat Syphilis.pdf
Are There Any Natural Remedies To Treat Syphilis.pdfAre There Any Natural Remedies To Treat Syphilis.pdf
Are There Any Natural Remedies To Treat Syphilis.pdf
Little Cross Family Clinic
 
Superficial & Deep Fascia of the NECK.pptx
Superficial & Deep Fascia of the NECK.pptxSuperficial & Deep Fascia of the NECK.pptx
Superficial & Deep Fascia of the NECK.pptx
Dr. Rabia Inam Gandapore
 
Triangles of Neck and Clinical Correlation by Dr. RIG.pptx
Triangles of Neck and Clinical Correlation by Dr. RIG.pptxTriangles of Neck and Clinical Correlation by Dr. RIG.pptx
Triangles of Neck and Clinical Correlation by Dr. RIG.pptx
Dr. Rabia Inam Gandapore
 
ARTHROLOGY PPT NCISM SYLLABUS AYURVEDA STUDENTS
ARTHROLOGY PPT NCISM SYLLABUS AYURVEDA STUDENTSARTHROLOGY PPT NCISM SYLLABUS AYURVEDA STUDENTS
ARTHROLOGY PPT NCISM SYLLABUS AYURVEDA STUDENTS
Dr. Vinay Pareek
 
Physiology of Special Chemical Sensation of Taste
Physiology of Special Chemical Sensation of TastePhysiology of Special Chemical Sensation of Taste
Physiology of Special Chemical Sensation of Taste
MedicoseAcademics
 
Evaluation of antidepressant activity of clitoris ternatea in animals
Evaluation of antidepressant activity of clitoris ternatea in animalsEvaluation of antidepressant activity of clitoris ternatea in animals
Evaluation of antidepressant activity of clitoris ternatea in animals
Shweta
 
Prix Galien International 2024 Forum Program
Prix Galien International 2024 Forum ProgramPrix Galien International 2024 Forum Program
Prix Galien International 2024 Forum Program
Levi Shapiro
 
Pharynx and Clinical Correlations BY Dr.Rabia Inam Gandapore.pptx
Pharynx and Clinical Correlations BY Dr.Rabia Inam Gandapore.pptxPharynx and Clinical Correlations BY Dr.Rabia Inam Gandapore.pptx
Pharynx and Clinical Correlations BY Dr.Rabia Inam Gandapore.pptx
Dr. Rabia Inam Gandapore
 
Alcohol_Dr. Jeenal Mistry MD Pharmacology.pdf
Alcohol_Dr. Jeenal Mistry MD Pharmacology.pdfAlcohol_Dr. Jeenal Mistry MD Pharmacology.pdf
Alcohol_Dr. Jeenal Mistry MD Pharmacology.pdf
Dr Jeenal Mistry
 
Maxilla, Mandible & Hyoid Bone & Clinical Correlations by Dr. RIG.pptx
Maxilla, Mandible & Hyoid Bone & Clinical Correlations by Dr. RIG.pptxMaxilla, Mandible & Hyoid Bone & Clinical Correlations by Dr. RIG.pptx
Maxilla, Mandible & Hyoid Bone & Clinical Correlations by Dr. RIG.pptx
Dr. Rabia Inam Gandapore
 
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...
kevinkariuki227
 
Charaka Samhita Sutra sthana Chapter 15 Upakalpaniyaadhyaya
Charaka Samhita Sutra sthana Chapter 15 UpakalpaniyaadhyayaCharaka Samhita Sutra sthana Chapter 15 Upakalpaniyaadhyaya
Charaka Samhita Sutra sthana Chapter 15 Upakalpaniyaadhyaya
Dr KHALID B.M
 
Non-respiratory Functions of the Lungs.pdf
Non-respiratory Functions of the Lungs.pdfNon-respiratory Functions of the Lungs.pdf
Non-respiratory Functions of the Lungs.pdf
MedicoseAcademics
 
Flu Vaccine Alert in Bangalore Karnataka
Flu Vaccine Alert in Bangalore KarnatakaFlu Vaccine Alert in Bangalore Karnataka
Flu Vaccine Alert in Bangalore Karnataka
addon Scans
 
How to Give Better Lectures: Some Tips for Doctors
How to Give Better Lectures: Some Tips for DoctorsHow to Give Better Lectures: Some Tips for Doctors
How to Give Better Lectures: Some Tips for Doctors
LanceCatedral
 
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdf
ARTIFICIAL INTELLIGENCE IN  HEALTHCARE.pdfARTIFICIAL INTELLIGENCE IN  HEALTHCARE.pdf
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdf
Anujkumaranit
 
NVBDCP.pptx Nation vector borne disease control program
NVBDCP.pptx Nation vector borne disease control programNVBDCP.pptx Nation vector borne disease control program
NVBDCP.pptx Nation vector borne disease control program
Sapna Thakur
 
How STIs Influence the Development of Pelvic Inflammatory Disease.pptx
How STIs Influence the Development of Pelvic Inflammatory Disease.pptxHow STIs Influence the Development of Pelvic Inflammatory Disease.pptx
How STIs Influence the Development of Pelvic Inflammatory Disease.pptx
FFragrant
 
basicmodesofventilation2022-220313203758.pdf
basicmodesofventilation2022-220313203758.pdfbasicmodesofventilation2022-220313203758.pdf
basicmodesofventilation2022-220313203758.pdf
aljamhori teaching hospital
 

Recently uploaded (20)

ACUTE SCROTUM.....pdf. ACUTE SCROTAL CONDITIOND
ACUTE SCROTUM.....pdf. ACUTE SCROTAL CONDITIONDACUTE SCROTUM.....pdf. ACUTE SCROTAL CONDITIOND
ACUTE SCROTUM.....pdf. ACUTE SCROTAL CONDITIOND
 
Are There Any Natural Remedies To Treat Syphilis.pdf
Are There Any Natural Remedies To Treat Syphilis.pdfAre There Any Natural Remedies To Treat Syphilis.pdf
Are There Any Natural Remedies To Treat Syphilis.pdf
 
Superficial & Deep Fascia of the NECK.pptx
Superficial & Deep Fascia of the NECK.pptxSuperficial & Deep Fascia of the NECK.pptx
Superficial & Deep Fascia of the NECK.pptx
 
Triangles of Neck and Clinical Correlation by Dr. RIG.pptx
Triangles of Neck and Clinical Correlation by Dr. RIG.pptxTriangles of Neck and Clinical Correlation by Dr. RIG.pptx
Triangles of Neck and Clinical Correlation by Dr. RIG.pptx
 
ARTHROLOGY PPT NCISM SYLLABUS AYURVEDA STUDENTS
ARTHROLOGY PPT NCISM SYLLABUS AYURVEDA STUDENTSARTHROLOGY PPT NCISM SYLLABUS AYURVEDA STUDENTS
ARTHROLOGY PPT NCISM SYLLABUS AYURVEDA STUDENTS
 
Physiology of Special Chemical Sensation of Taste
Physiology of Special Chemical Sensation of TastePhysiology of Special Chemical Sensation of Taste
Physiology of Special Chemical Sensation of Taste
 
Evaluation of antidepressant activity of clitoris ternatea in animals
Evaluation of antidepressant activity of clitoris ternatea in animalsEvaluation of antidepressant activity of clitoris ternatea in animals
Evaluation of antidepressant activity of clitoris ternatea in animals
 
Prix Galien International 2024 Forum Program
Prix Galien International 2024 Forum ProgramPrix Galien International 2024 Forum Program
Prix Galien International 2024 Forum Program
 
Pharynx and Clinical Correlations BY Dr.Rabia Inam Gandapore.pptx
Pharynx and Clinical Correlations BY Dr.Rabia Inam Gandapore.pptxPharynx and Clinical Correlations BY Dr.Rabia Inam Gandapore.pptx
Pharynx and Clinical Correlations BY Dr.Rabia Inam Gandapore.pptx
 
Alcohol_Dr. Jeenal Mistry MD Pharmacology.pdf
Alcohol_Dr. Jeenal Mistry MD Pharmacology.pdfAlcohol_Dr. Jeenal Mistry MD Pharmacology.pdf
Alcohol_Dr. Jeenal Mistry MD Pharmacology.pdf
 
Maxilla, Mandible & Hyoid Bone & Clinical Correlations by Dr. RIG.pptx
Maxilla, Mandible & Hyoid Bone & Clinical Correlations by Dr. RIG.pptxMaxilla, Mandible & Hyoid Bone & Clinical Correlations by Dr. RIG.pptx
Maxilla, Mandible & Hyoid Bone & Clinical Correlations by Dr. RIG.pptx
 
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...
 
Charaka Samhita Sutra sthana Chapter 15 Upakalpaniyaadhyaya
Charaka Samhita Sutra sthana Chapter 15 UpakalpaniyaadhyayaCharaka Samhita Sutra sthana Chapter 15 Upakalpaniyaadhyaya
Charaka Samhita Sutra sthana Chapter 15 Upakalpaniyaadhyaya
 
Non-respiratory Functions of the Lungs.pdf
Non-respiratory Functions of the Lungs.pdfNon-respiratory Functions of the Lungs.pdf
Non-respiratory Functions of the Lungs.pdf
 
Flu Vaccine Alert in Bangalore Karnataka
Flu Vaccine Alert in Bangalore KarnatakaFlu Vaccine Alert in Bangalore Karnataka
Flu Vaccine Alert in Bangalore Karnataka
 
How to Give Better Lectures: Some Tips for Doctors
How to Give Better Lectures: Some Tips for DoctorsHow to Give Better Lectures: Some Tips for Doctors
How to Give Better Lectures: Some Tips for Doctors
 
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdf
ARTIFICIAL INTELLIGENCE IN  HEALTHCARE.pdfARTIFICIAL INTELLIGENCE IN  HEALTHCARE.pdf
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdf
 
NVBDCP.pptx Nation vector borne disease control program
NVBDCP.pptx Nation vector borne disease control programNVBDCP.pptx Nation vector borne disease control program
NVBDCP.pptx Nation vector borne disease control program
 
How STIs Influence the Development of Pelvic Inflammatory Disease.pptx
How STIs Influence the Development of Pelvic Inflammatory Disease.pptxHow STIs Influence the Development of Pelvic Inflammatory Disease.pptx
How STIs Influence the Development of Pelvic Inflammatory Disease.pptx
 
basicmodesofventilation2022-220313203758.pdf
basicmodesofventilation2022-220313203758.pdfbasicmodesofventilation2022-220313203758.pdf
basicmodesofventilation2022-220313203758.pdf
 

Dengue fever

  • 1. PRESENTED BY- Farazul Hoda M.PHARM(PHARMACY PRACTICE) 2ND SEMESTER
  • 2.
  • 3. • Dengue is a mosquito-borne, viral infection transmitted by Aedes mosquitoes. • The infection causes flu-like illness, and occasionally develops into a potentially lethal complication called severe dengue. • Common name of the disease is ‘break-bone fever’ .
  • 4. HISTORY • Epidemics of an illness resembling dengue occurred in 1779, 1780 in three continents- Asia, Africa and North America. • First epidemic of DHF occurred in Manila, Philippines 1950. • In India dengue virus was first isolated in Calcutta in 1945. • Epidemic of Dengue hemorrhagic fever(DHF) first occurred in Calcutta in 1963.
  • 5.
  • 6.
  • 7.
  • 8.
  • 9. It is caused by a virus (Dengue Virus) Four different types (Type 1,2,3,4) AGE & SEX GROUPS AFFECTED • All age groups & both sexes are affected • Children > Adults • Female > Male (severe) • Deaths are more in children during DHF outbreak • Immune status
  • 10.
  • 11.
  • 12. Disease occurs more frequently in the rainy season and immediately afterwards (July to October) in India.
  • 13.
  • 14.
  • 15. • Fever: continuous for 3 to 7 days • Severe headache • Joint pain, muscle pain, pain behind eyeballs •Nausea, vomiting, and rash • In very rare cases, the condition may worsen into dengue haemorrhagic fever, leading to internal bleeding, shock, or even death.
  • 16. •Blood pressure •Evidence of bleeding in skin or other sites •Hydration status •Evidence of increased vascular permeability- pleural effusions, ascites •Tourniquet test
  • 17. Clinical laboratory tests • CBC--WBC, platelets, hematocrit • Albumin • Liver function tests • Urine--check for microscopic hematuria  Dengue-specific tests • Virus isolation • Serology • Antigen • Antibody: IgM,IgG
  • 18. •At present, no specific drug that can treat dengue fever effectively. • Patient should be isolated in a mosquito-free environment to prevent the spread of disease.
  • 19. •Fluids • Rest • Antipyretics (avoid aspirin and nonsteroidal anti- inflammatory drugs) • Monitor blood pressure, hematocrit, platelet count, level of consciousness
  • 20. • No licensed vaccine at present • Recently Tetravalent Dengue Vaccine phase 3 trial completed in Asia.
  • 21. The first dengue vaccine, Dengvaxia® (CYD-TDV) developed by Sanofi Pasteur was licensed in December 2015 and has now been approved by regulatory authorities in 20 countries for use in endemic areas in persons ranging from 9-45 years of age. In April 2016, WHO issued a conditional recommendation on the use of the vaccine for areas in which dengue is highly endemic as defined by seroprevalence of 70% or higher. In November 2017, the results of an additional analysis to retrospectively determine serostatus at the time of vaccination were released. The analysis showed that the subset of trial participants who were inferred to be seronegative at time of first vaccination had a higher risk of more severe dengue and hospitalizations from dengue compared to unvaccinated participants. Immunization
  • 22. 1.Rajapakse S, Rodrigo C, Rajapakse A. Treatment of dengue fever. Infection and drug resistance. 2012;5:103. 2.Deen JL, Harris E, Wills B, Balmaseda A, Hammond SN, Rocha C, Dung NM, Hung NT, Hien TT, Farrar JJ. The WHO dengue classification and case definitions: time for a reassessment. The Lancet. 2006 Jul 8;368(9530):170-3. 3.Wiwanitkit V (July 2010). "Dengue fever: diagnosis and treatment". Expert Review of Anti-Infective Therapy. 8 (7): 841–5 References