Understanding the basics on COV 19 including the last update on spreading and molecular structure of virions. It also includes information on pathological findings and treatments strategies

1. COVID19
FROM A TO Z
Goran Q. Othman
Cell Biologist
Erbil Polytechnic University
5th April 2020

2. The Origin of SARS-COV2

3. The Origin of SARS-COV2

5. The growing curve of confirmed cases per day
Note the growth rate…….. From tens per day in Feb to 100k per day in April

6. The growing curve of death cases since 30 days of 1st recorded

10. The Math. Of Epidemic: SIR Model

11. The Math. Of Epidemic: SIR Model

12. The Math. Of Epidemic: SIR Model

13. The Math. Of Epidemic: SIR Model

14. One of the controlling strategies is

17. Role of S glycoprotein and ACE2 in virus entry

21. Pathological Findings

22. Problems facing our immune system

24. Problems facing our immune system

26. Best targets for treatment…..Blocking infection
Kruse RL. Therapeutic strategies in an outbreak scenario to
treat the novel coronavirus originating in Wuhan,
China [version 2; peer review: 2 approved] F1000Research 2020,
9:72 (https://doi.org/10.12688/f1000research.22211.2)

27. Current Treatment Options
 Among the potential treatments for COVID-19 that are
undergoing clinical trials to assess their safety and efficacy against
the disease are:
 remdesivir (investigational)
 lopinavir/ritonavir (currently authorised as an anti-HIV medicine)
 chloroquine and hydroxychloroquine (currently authorised at
national level as treatments against malaria and certain
autoimmune diseases such as rheumatoid arthritis)
 systemic interferons and in particular interferon beta (currently
authorised to treat diseases such as multiple sclerosis)
 monoclonal antibodies with activity against components of the
immune system
 Ivermectin which is used as antiparasites especially related to skin