Coronary artery disease among asymptomatic diabetic and non-diabetic patients undergoing coronary CT angiography
•Download as PPT, PDF•
2 likes•710 views
This study aimed to determine the prevalence and severity of coronary artery disease (CAD) in asymptomatic diabetic and nondiabetic patients using coronary CT angiography (CCTA). The study found CAD was present in 93% of asymptomatic diabetics compared to 73% of nondiabetics. Obstructive CAD was more common in diabetics at 29% versus 6.6% in nondiabetics. Diabetics also had higher total Agatston scores and more coronary segments with atherosclerosis. The results indicate asymptomatic diabetics have a high prevalence of CAD, suggesting CCTA may be useful for evaluating subclinical disease in this high risk group.
Report
Share
Report
Share
![[object Object],[object Object],[object Object],_______________________________________________________________________________ ,[object Object],[object Object],[object Object],Zeina et al, Coronary Artery Disease 2008, 19:37–41 Introduction](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)
Recommended
Clinical Decision Support Systems and their Impact on Cardiovascular Disease ...
This document summarizes research on the use of clinical decision support systems (CDSS) to improve care for cardiovascular disease. It finds that CDSS can reduce mortality for congestive heart failure patients and improve guideline adherence for hypertension, but do not necessarily lower blood pressure. CDSS also improve management of dyslipidemia and medication prescription post-myocardial infarction. However, more rigorous randomized studies are still needed to fully understand the costs and long-term impacts of implementing CDSS for cardiovascular disease.
STEMI and Cardiogenic Shock - Dr. Henriques
Ponencia presentada por el Dr. Jose Paulo Simâo Henriques en la Reunión EuroIMAT 2020, celebrada en Barcelona (20 y 21 de febrero de 2020).
ACP National meeting 2015 by Krittanawong et al - All Rights Reserved
ACP National meeting 2015 by Krittanawong et al - All Rights Reserved Chayakrit (Charles) Krittanawong
This study investigated the optimal serum potassium (K) and magnesium (Mg) levels in patients admitted to coronary care units (CCU). The study retrospectively analyzed over 8,000 CCU patients and their K and Mg levels. It found a U-shaped relationship between mortality and both K and Mg levels. Serum K <3.5 mEq/L or ≥4.5 mEq/L and serum Mg ≥2.4 mg/dL were associated with higher mortality. The study concluded the optimal levels are K of 3.5-<4.5 mEq/L and Mg <2.4 mg/dL for CCU patients.Geographic Variation in Implantable Cardioverter Defibrillator Utilization 5....
Geographic Variation in Implantable Cardioverter Defibrillator Utilization 5....Leonard Davis Institute of Health Economics
The document analyzes geographic variation in the use of implantable cardioverter-defibrillators (ICDs) for patients with heart failure and the relationship between ICD use and heart failure mortality between 2002-2006. The study found that localities with greater increases in ICD use saw lower heart failure mortality rates, and that underuse of ICDs resulted in an estimated 900-1,200 additional premature deaths. Increasing ICD use was associated with improved survival at a population level.An Ill-identified Classification to Predict Cardiac Disease Using Data Cluste...
The health care industry contains large amount of
health care data with hidden information. This information is
useful for making effective decision. For getting appropriate
result from the hidden information computer based data mining
techniques are used. Previously Neural Network (NN) is
widely used for predicting cardiac disease. In this paper, a
Cardiac Disease Prediction System (CDPS) is developed by
using data clustering. The CDPS system uses 15 parameters to
predict the disease, for example BP, Obesity, cholesterol, etc.
This 15 attributes like sex, age, weight are given as the input.
In this paper by using the patient’s medical record, an illdefined classification is used at the early stage of the patient to
diagnose the cardiac disease. Based on the result the patients
are advised to keep the sensor to predict them.
Chronic Conditions of as Predictors of Hospitalization Following an Emergency...
Accepted and Presented in the Session of Injury Control and Emergency Health Services of American Public Health Association 2016 Annual Meeting and Expo Held in October 31.
For APHA member access, https://apha.confex.com/apha/144am/icehs/papers/index.cgi?username=359723&password=722348
[IJET-V1I4P17] Authors: Fahimuddin. Shaik, Dr.Anil Kumar Sharma, Dr.Syed.Must...
[IJET-V1I4P17] Authors: Fahimuddin. Shaik, Dr.Anil Kumar Sharma, Dr.Syed.Must...IJET - International Journal of Engineering and Techniques
As Diabetes Mellitus combined with other ailments will become a deadly combination, hence there
is an urgent need to break the link between diabetes and its related complications. For this purpose image
processing based analysis can potentially be helpful for earlier detection, education and treatment. Medical
image analysis of Diabetic patients with its related complications such as DR, CVD & Diabetic
Myonecrosis (i.e. on Retinal Images, Coronary angiographs, Electron micrographs, MRI etc) is to be the
aprioristic because of its more prevalence. Thus the main work of this paper is on literature review about
Diabetes and Imaging such as the Prevalence, Classification, Causes and Medical Imaging & Survey of
Image processing methods applied on Diabetic Related Causes.
Keywords — Image, segmentation, retinopathy, Myonecrosis,Abordaje terapéutico de la dislipemia en el paciente con enfermedad renal cró...
Abordaje terapéutico de la dislipemia en el paciente con enfermedad renal cró...Sociedad Española de Cardiología
Un nuevo horizonte en el tratamiento de las dislipemias
14/09/15 18:00h-19:30h Casa del Corazón (Madrid)
http://objetivoLDL.secardiologia.es
#objetivoLDL
Abordaje terapéutico de la dislipemia en el paciente con enfermedad renal crónica
Dr. Jesús Egido de los Ríos, Jefe Servicio Nefrología e Hipertensión Fundación Jiménez Díaz (Madrid)Recommended
Clinical Decision Support Systems and their Impact on Cardiovascular Disease ...
This document summarizes research on the use of clinical decision support systems (CDSS) to improve care for cardiovascular disease. It finds that CDSS can reduce mortality for congestive heart failure patients and improve guideline adherence for hypertension, but do not necessarily lower blood pressure. CDSS also improve management of dyslipidemia and medication prescription post-myocardial infarction. However, more rigorous randomized studies are still needed to fully understand the costs and long-term impacts of implementing CDSS for cardiovascular disease.
STEMI and Cardiogenic Shock - Dr. Henriques
Ponencia presentada por el Dr. Jose Paulo Simâo Henriques en la Reunión EuroIMAT 2020, celebrada en Barcelona (20 y 21 de febrero de 2020).
ACP National meeting 2015 by Krittanawong et al - All Rights Reserved
ACP National meeting 2015 by Krittanawong et al - All Rights Reserved Chayakrit (Charles) Krittanawong
This study investigated the optimal serum potassium (K) and magnesium (Mg) levels in patients admitted to coronary care units (CCU). The study retrospectively analyzed over 8,000 CCU patients and their K and Mg levels. It found a U-shaped relationship between mortality and both K and Mg levels. Serum K <3.5 mEq/L or ≥4.5 mEq/L and serum Mg ≥2.4 mg/dL were associated with higher mortality. The study concluded the optimal levels are K of 3.5-<4.5 mEq/L and Mg <2.4 mg/dL for CCU patients.Geographic Variation in Implantable Cardioverter Defibrillator Utilization 5....
Geographic Variation in Implantable Cardioverter Defibrillator Utilization 5....Leonard Davis Institute of Health Economics
The document analyzes geographic variation in the use of implantable cardioverter-defibrillators (ICDs) for patients with heart failure and the relationship between ICD use and heart failure mortality between 2002-2006. The study found that localities with greater increases in ICD use saw lower heart failure mortality rates, and that underuse of ICDs resulted in an estimated 900-1,200 additional premature deaths. Increasing ICD use was associated with improved survival at a population level.An Ill-identified Classification to Predict Cardiac Disease Using Data Cluste...
The health care industry contains large amount of
health care data with hidden information. This information is
useful for making effective decision. For getting appropriate
result from the hidden information computer based data mining
techniques are used. Previously Neural Network (NN) is
widely used for predicting cardiac disease. In this paper, a
Cardiac Disease Prediction System (CDPS) is developed by
using data clustering. The CDPS system uses 15 parameters to
predict the disease, for example BP, Obesity, cholesterol, etc.
This 15 attributes like sex, age, weight are given as the input.
In this paper by using the patient’s medical record, an illdefined classification is used at the early stage of the patient to
diagnose the cardiac disease. Based on the result the patients
are advised to keep the sensor to predict them.
Chronic Conditions of as Predictors of Hospitalization Following an Emergency...
Accepted and Presented in the Session of Injury Control and Emergency Health Services of American Public Health Association 2016 Annual Meeting and Expo Held in October 31.
For APHA member access, https://apha.confex.com/apha/144am/icehs/papers/index.cgi?username=359723&password=722348
[IJET-V1I4P17] Authors: Fahimuddin. Shaik, Dr.Anil Kumar Sharma, Dr.Syed.Must...
[IJET-V1I4P17] Authors: Fahimuddin. Shaik, Dr.Anil Kumar Sharma, Dr.Syed.Must...IJET - International Journal of Engineering and Techniques
As Diabetes Mellitus combined with other ailments will become a deadly combination, hence there
is an urgent need to break the link between diabetes and its related complications. For this purpose image
processing based analysis can potentially be helpful for earlier detection, education and treatment. Medical
image analysis of Diabetic patients with its related complications such as DR, CVD & Diabetic
Myonecrosis (i.e. on Retinal Images, Coronary angiographs, Electron micrographs, MRI etc) is to be the
aprioristic because of its more prevalence. Thus the main work of this paper is on literature review about
Diabetes and Imaging such as the Prevalence, Classification, Causes and Medical Imaging & Survey of
Image processing methods applied on Diabetic Related Causes.
Keywords — Image, segmentation, retinopathy, Myonecrosis,Abordaje terapéutico de la dislipemia en el paciente con enfermedad renal cró...
Abordaje terapéutico de la dislipemia en el paciente con enfermedad renal cró...Sociedad Española de Cardiología
Un nuevo horizonte en el tratamiento de las dislipemias
14/09/15 18:00h-19:30h Casa del Corazón (Madrid)
http://objetivoLDL.secardiologia.es
#objetivoLDL
Abordaje terapéutico de la dislipemia en el paciente con enfermedad renal crónica
Dr. Jesús Egido de los Ríos, Jefe Servicio Nefrología e Hipertensión Fundación Jiménez Díaz (Madrid)Base Primary Prevention Decision Model
Presented by Stephanie Earnshaw, MD, MPH, at UCSF's symposium "The Role of Risk Stratification and Biomarkers in Prevention of Cardiovascular Disease" in Jan 2012.
Thierry Chassaulet: Predictive risk modelling: Does technique or time matter?
1. Three predictive risk modeling techniques - logistic regression, decision trees, and neural networks - were compared to predict hospital readmissions within various timeframes using patient admission data.
2. Logistic regression and decision trees had similar predictive accuracy around 70-72% while neural networks had slightly higher sensitivity.
3. Prior emergency admissions and a measure of condition severity were the strongest predictors of readmission across all models.
4. While neural networks had the best performance, logistic regression provides the most easily interpretable results for non-technical audiences.
Dores et al
Compliance of pharmacological treatment for non-ST-elevation acute coronary syndromes with contemporary guidelines: influence on outcomes
Authors: Hélder Dores, Carlos Aguiar, Jorge Ferreira, Jorge Mimoso, Sílvia Monteiro, Filipe Seixo, José Ferreira Santos, On behalf of Portuguese Registry on Acute Coronary Syndromes (ProACS) Investigators
Measuring long term effect of Telecare on Chronic Diseases by Masatugu Tsuji,
Measuring long term effect of Telecare on Chronic Diseases by Masatugu Tsuji,Apollo Hospitals Group and ATNF
Measuring long term effect of Telecare on Chronic Diseases by Masatugu Tsuji, Graduate School of Applied Informatics, University of Hyogo, JapanIje Okafor_Poster
This study examined whether using a weighted average of past blood pressure (BP) measurements (antecedent BP) is a better predictor of cardiovascular disease (CVD) risk than the simple average of antecedent BP. The study used data from the Framingham Heart Study and found that while the weighted average model showed a slightly higher predictive accuracy than the simple average model based on the C-statistic, statistical tests did not show a significant improvement, indicating refinement is needed. Future work could explore different populations and weighting methods to potentially find a statistically significant improved predictive model using weighted antecedent BP.
Outcomes of Carotid Stent Systems Versus Endarterectomy 4.29.08
Outcomes of Carotid Stent Systems Versus Endarterectomy 4.29.08Leonard Davis Institute of Health Economics
Patients who received carotid stent systems (CSS) had slightly higher mortality and major adverse clinical event rates compared to patients receiving carotid endarterectomy (CE). These differences were more pronounced when comparing CSS patients to contemporary CE patients. While CSS is an approved alternative to CE for carotid artery stenosis, concerns remain about its outcomes compared to CE, particularly in non-experimental settings. This study used propensity score matching to compare outcomes of Medicare patients receiving CSS or CE after the 2005 Medicare coverage decision for CSS.Purple and white modern advertising presentation
The document summarizes a study that used machine learning models to predict patient survival from heart failure and identify important risk factors. [1] The study analyzed data from 299 heart failure patients, applying classifiers to predict survival and rank risk factors. [2] The models identified serum creatinine and ejection fraction as the most important predictors of survival. [3] Using only these two factors resulted in more accurate predictions than using all available data, suggesting these metrics could help doctors predict patient outcomes.
Aspirin as Prevention Therapy for Cardiovascular Events in patients with Diab...
The Role of Aspirin in the primary prevention of cardiovascular disease in patients with diabetes, especially T2DM - current knowledge and recommendations -
Central Adiposity and Mortality after First-Ever Acute Ischemic Stroke
Erwin Chiquete a José L. Ruiz-Sandoval c Luis Murillo-Bonilla e
Carolina León-Jiménez g Bertha Ruiz-Madrigal d, f Erika Martínez-López d, f
Sonia Román d, f Arturo Panduro d, f Alma Ramos b Carlos Cantú-Brito
Background: The waist-to-height ratio (WHtR) may be a better
adiposity measure than the body mass index (BMI). We
evaluated the prognostic performance of WHtR in patients
with acute ischemic stroke (AIS). Methods: First, we compared
WHtR and BMI as adiposity measures in 712 healthy
adults by tetrapolar bioimpedance analysis. Thereafter,
baseline WHtR was analyzed as predictor of 12-month allcause
mortality in 821 Mexican mestizo adults with first-ever
AIS by a Cox proportional hazards model adjusted for baseline
predictors. Results: In healthy individuals, WHtR correlated
higher than BMI with total fat mass and showed a higher
accuracy in identifying a high percentage of body fat (p <
0.01). In AIS patients a U-shaped relationship was observed
between baseline WHtR and mortality (fatality rate 29.1%).
On multivariate analysis, baseline WHtR ≤ 0.300 or >0.800 independently
predicted 12-month all-cause mortality (h
Critical Illness Outcomes in General Versus Specialty Intensive Care Units 5....
Critical Illness Outcomes in General Versus Specialty Intensive Care Units 5....Leonard Davis Institute of Health Economics
This study compared outcomes of patients admitted to general intensive care units (ICUs) versus specialty ICUs for specific conditions like heart attacks or pneumonia. The study analyzed data on over 84,000 patients from 124 ICUs. It found that admission to an "ideal" specialty ICU matched to a patient's condition did not generally provide a survival benefit compared to general ICU care. However, admission to a "non-ideal" specialty ICU, or boarding, was associated with higher risk-adjusted mortality. The results suggest specialty ICUs may not necessarily improve survival outcomes.How Much Does A Hospital Day Cost?
This document summarizes a study that used hospital discharge data to estimate the average daily cost of hospitalization by diagnosis and level of care (ICU/CCU or regular care). The study found that:
1) The average daily cost across all conditions was $2,401 in the ICU/CCU and $1,122 in regular care.
2) Daily costs varied significantly by diagnosis, ranging from $1,241 to $3,315 in the ICU/CCU and $1,176 to $3,081 in regular care.
3) Estimating daily costs by diagnosis and care level can provide useful information for cost-effectiveness analyses of healthcare interventions.
12471_2015_Article_733
This study analyzed clinical outcomes in 2002 STEMI patients undergoing primary PCI. Patients were divided into 3 age groups: <60, 60-79, and ≥80 years old. The study found that rates of adverse events like mortality, recurrent MI, stroke, and major bleeding increased with age. Specifically, patients ≥80 years old had higher rates of comorbidities and experienced the highest rates of ischaemic and bleeding complications compared to younger patients, even after adjusting for confounding factors. The study concluded that elderly STEMI patients, especially those ≥80 years old, are a high-risk group that requires individualized therapy to optimize clinical outcomes.
Risk factors for adverse coutcomes
This study analyzed data from over 30,000 patients with heart failure (HF) to identify predictors of adverse outcomes based on left ventricular ejection fraction (LVEF). Patients were categorized as having preserved LVEF (≥50%), borderline LVEF (41-49%), or reduced LVEF (≤40%). Over a median follow up of 1.8 years, 26.8% of patients died, 26.9% were hospitalized for HF, and 67.4% were hospitalized for any reason. Multivariable models found that nearly all tested predictors, such as demographics, medical history, and comorbidities, performed similarly for predicting death and hospitalization across the different LVEF
Novel Method for Automated Analysis of Retinal Images: Results in Subjects wi...
Michele Cavallari, Claudio Stamile, Renato Umeton, Francesco Calimeri, and Francesco Orzi
Morphological analysis of the retinal vessels by fundoscopy provides noninvasive means for detecting and staging systemic microvascular damage. However, full exploitation of fundoscopy in clinical settings is limited by paucity of quantitative, objective information obtainable through the observer-driven evaluations currently employed in routine practice. Here, we report on the development of a semiautomated, computer-based method to assess retinal vessel morphology. The method allows simultaneous and operator-independent quantitative assessment of arteriole-to-venule ratio, tortuosity index, and mean fractal dimension. The method was implemented in two conditions known for being associated with retinal vessel changes: hypertensive retinopathy and Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL). The results showed that our approach is effective in detecting and quantifying the retinal vessel abnormalities. Arteriole-to-venule ratio, tortuosity index, and mean fractal dimension were altered in the subjects with hypertensive retinopathy or CADASIL with respect to age- and gender-matched controls. The interrater reliability was excellent for all the three indices (intraclass correlation coefficient ≥ 85%). The method represents simple and highly reproducible means for discriminating pathological conditions characterized by morphological changes of retinal vessels. The advantages of our method include simultaneous and operator-independent assessment of different parameters and improved reliability of the measurements.
The Effect of Demographic Data and Hemoglobin A 1c on Treatment Outcomes in P...
Objective: Diabetes mellitus, the most common cause of non-traumatic foot amputations, is a life-threatening condition due to its high mortality and morbidity. In our study, we retrospectively evaluated our patients with diabetic foot syndrome in our clinic. Materials and Methods: The demographic data, duration of diabetes, Wagner classification, haemoglobin A 1c (HbA1c) levels, white blood cell, C-reactive protein sedimentation levels, hospital stay, and treatment results were evaluated retrospectively in 14 patients with diabetic foot between January 2017 and December 2018. Results: The mean age of the patients was 62.43 ± 7.7 years. Of the 14 patients, 3 were females and 11 were males. All 14 patients were type 2 diabetes mellitus. When diabetic foot Wagner classification was performed, 6 patients were evaluated as Wagner 2, five patients were Wagner 3, and three patients were evaluated as Wagner 4. Nine patients had complete amputation and 3 had vascular surgery. Conclusion: Although the level of HbA1c is below the target level, the risk of diabetic foot is increased when there is no adequate diabetes mellitus foot training. Inadequate diabetic patient education and hospitalization of patients after infection progress the amputation rate.
Seattle heart failure model
The Seattle Heart Failure Model was developed by researchers at the University of Washington to accurately predict 1, 2, and 3-year survival rates for patients with heart failure based on simple clinical variables. The model also estimates how a patient's survival would be impacted by various heart failure medications and devices. Validation testing found the model provided excellent accuracy. It is available online and allows clinicians to estimate how adding different treatment options could extend a patient's predicted lifespan. The researchers hope this model will encourage both patients and doctors to more frequently use proven life-saving heart failure medications and devices.
HEC 2014 / James Peake: The Quality Journey of the U.S. Department of Veteran...
HEC 2014 / James Peake: The Quality Journey of the U.S. Department of Veteran...Ahjo Communications Oy
The presentation Dr. James Peake gave in the Healthcare Executive Circle 2014 -seminar in 6th of February, 2014.
http://hec2014.fi/Differences in clinical characteristics and its effect for outcomes
The document summarizes differences in characteristics and outcomes between Western and Korean patients with acute heart failure based on an analysis of registry data. It finds that compared to Western registries, Korean patients tended to be relatively younger (mean age 69 years old), with a higher rate of first-time heart failure presentations (52.1%) and lower rates of hypertension and coronary artery disease as the cause of heart failure. Korean patients also presented with lower blood pressures on admission. In-hospital mortality rates were similar at around 5%, though Korean patients had lower 90-day mortality. Factors like creatinine levels, blood pressure, BMI and sodium levels similarly predicted outcomes. Rates of beta blocker use at discharge were also lower for Korean
Ischemia Trial
The document reports on a study from the ISCHEMIA trial investigating the impact of complete versus incomplete revascularization on clinical outcomes in patients with stable ischemic heart disease treated with an invasive versus conservative strategy. It finds that among patients treated with an invasive strategy, complete anatomic or functional revascularization was associated with improved outcomes compared to incomplete revascularization. However, after adjustment for covariates, the differences in outcomes between complete and incomplete revascularization were no longer statistically significant.
Stopdapt 2 randomized clinical trial
the 1-year cumulative incidence of a composite end point consisting of cardiovascular death, myocardial infarction, ischemic or hemorrhagic stroke, definite stent thrombosis, and major bleeding was 2.4% in the 1-month DAPT group and 3.7% in the 12-month DAPT group, a difference that met the noninferiority margin of a hazard ratio of 0.5, as well as superiority.
204 prevalence of inflammatory cells in non ruptured atherosclerotic plaques
This document summarizes a post-mortem study examining the prevalence of inflammatory cells in non-ruptured atherosclerotic plaques. The study found that moderate or heavy staining for macrophages was present in 45% of femoral artery cross-sections and 84% of femoral arteries had at least one cross-section with moderate/heavy inflammation. There was no observed relationship between the degree of inflammation in the left and right coronary arteries within individuals, indicating the level of local inflammation is locally determined with little predictive value for other arteries.
048 adventitial fat presentation
1) The study investigated the uptake of SPIO (superparamagnetic iron oxide), an MRI contrast agent, by periadventitial fat in an atherosclerosis mouse model.
2) Results showed significantly greater uptake of iron in the periadventitial fat of apoE k/o mice compared to control mice, as measured by iron particles and area.
3) Preliminary evidence also suggests uptake of iron in the periadventitial fat of atherosclerotic rabbits and humans, suggesting macrophage-like activity in this tissue that warrants further investigation into its role in atherosclerosis and potential applications for plaque imaging.
More Related Content
What's hot
Base Primary Prevention Decision Model
Presented by Stephanie Earnshaw, MD, MPH, at UCSF's symposium "The Role of Risk Stratification and Biomarkers in Prevention of Cardiovascular Disease" in Jan 2012.
Thierry Chassaulet: Predictive risk modelling: Does technique or time matter?
1. Three predictive risk modeling techniques - logistic regression, decision trees, and neural networks - were compared to predict hospital readmissions within various timeframes using patient admission data.
2. Logistic regression and decision trees had similar predictive accuracy around 70-72% while neural networks had slightly higher sensitivity.
3. Prior emergency admissions and a measure of condition severity were the strongest predictors of readmission across all models.
4. While neural networks had the best performance, logistic regression provides the most easily interpretable results for non-technical audiences.
Dores et al
Compliance of pharmacological treatment for non-ST-elevation acute coronary syndromes with contemporary guidelines: influence on outcomes
Authors: Hélder Dores, Carlos Aguiar, Jorge Ferreira, Jorge Mimoso, Sílvia Monteiro, Filipe Seixo, José Ferreira Santos, On behalf of Portuguese Registry on Acute Coronary Syndromes (ProACS) Investigators
Measuring long term effect of Telecare on Chronic Diseases by Masatugu Tsuji,
Measuring long term effect of Telecare on Chronic Diseases by Masatugu Tsuji,Apollo Hospitals Group and ATNF
Measuring long term effect of Telecare on Chronic Diseases by Masatugu Tsuji, Graduate School of Applied Informatics, University of Hyogo, JapanIje Okafor_Poster
This study examined whether using a weighted average of past blood pressure (BP) measurements (antecedent BP) is a better predictor of cardiovascular disease (CVD) risk than the simple average of antecedent BP. The study used data from the Framingham Heart Study and found that while the weighted average model showed a slightly higher predictive accuracy than the simple average model based on the C-statistic, statistical tests did not show a significant improvement, indicating refinement is needed. Future work could explore different populations and weighting methods to potentially find a statistically significant improved predictive model using weighted antecedent BP.
Outcomes of Carotid Stent Systems Versus Endarterectomy 4.29.08
Outcomes of Carotid Stent Systems Versus Endarterectomy 4.29.08Leonard Davis Institute of Health Economics
Patients who received carotid stent systems (CSS) had slightly higher mortality and major adverse clinical event rates compared to patients receiving carotid endarterectomy (CE). These differences were more pronounced when comparing CSS patients to contemporary CE patients. While CSS is an approved alternative to CE for carotid artery stenosis, concerns remain about its outcomes compared to CE, particularly in non-experimental settings. This study used propensity score matching to compare outcomes of Medicare patients receiving CSS or CE after the 2005 Medicare coverage decision for CSS.Purple and white modern advertising presentation
The document summarizes a study that used machine learning models to predict patient survival from heart failure and identify important risk factors. [1] The study analyzed data from 299 heart failure patients, applying classifiers to predict survival and rank risk factors. [2] The models identified serum creatinine and ejection fraction as the most important predictors of survival. [3] Using only these two factors resulted in more accurate predictions than using all available data, suggesting these metrics could help doctors predict patient outcomes.
Aspirin as Prevention Therapy for Cardiovascular Events in patients with Diab...
The Role of Aspirin in the primary prevention of cardiovascular disease in patients with diabetes, especially T2DM - current knowledge and recommendations -
Central Adiposity and Mortality after First-Ever Acute Ischemic Stroke
Erwin Chiquete a José L. Ruiz-Sandoval c Luis Murillo-Bonilla e
Carolina León-Jiménez g Bertha Ruiz-Madrigal d, f Erika Martínez-López d, f
Sonia Román d, f Arturo Panduro d, f Alma Ramos b Carlos Cantú-Brito
Background: The waist-to-height ratio (WHtR) may be a better
adiposity measure than the body mass index (BMI). We
evaluated the prognostic performance of WHtR in patients
with acute ischemic stroke (AIS). Methods: First, we compared
WHtR and BMI as adiposity measures in 712 healthy
adults by tetrapolar bioimpedance analysis. Thereafter,
baseline WHtR was analyzed as predictor of 12-month allcause
mortality in 821 Mexican mestizo adults with first-ever
AIS by a Cox proportional hazards model adjusted for baseline
predictors. Results: In healthy individuals, WHtR correlated
higher than BMI with total fat mass and showed a higher
accuracy in identifying a high percentage of body fat (p <
0.01). In AIS patients a U-shaped relationship was observed
between baseline WHtR and mortality (fatality rate 29.1%).
On multivariate analysis, baseline WHtR ≤ 0.300 or >0.800 independently
predicted 12-month all-cause mortality (h
Critical Illness Outcomes in General Versus Specialty Intensive Care Units 5....
Critical Illness Outcomes in General Versus Specialty Intensive Care Units 5....Leonard Davis Institute of Health Economics
This study compared outcomes of patients admitted to general intensive care units (ICUs) versus specialty ICUs for specific conditions like heart attacks or pneumonia. The study analyzed data on over 84,000 patients from 124 ICUs. It found that admission to an "ideal" specialty ICU matched to a patient's condition did not generally provide a survival benefit compared to general ICU care. However, admission to a "non-ideal" specialty ICU, or boarding, was associated with higher risk-adjusted mortality. The results suggest specialty ICUs may not necessarily improve survival outcomes.How Much Does A Hospital Day Cost?
This document summarizes a study that used hospital discharge data to estimate the average daily cost of hospitalization by diagnosis and level of care (ICU/CCU or regular care). The study found that:
1) The average daily cost across all conditions was $2,401 in the ICU/CCU and $1,122 in regular care.
2) Daily costs varied significantly by diagnosis, ranging from $1,241 to $3,315 in the ICU/CCU and $1,176 to $3,081 in regular care.
3) Estimating daily costs by diagnosis and care level can provide useful information for cost-effectiveness analyses of healthcare interventions.
12471_2015_Article_733
This study analyzed clinical outcomes in 2002 STEMI patients undergoing primary PCI. Patients were divided into 3 age groups: <60, 60-79, and ≥80 years old. The study found that rates of adverse events like mortality, recurrent MI, stroke, and major bleeding increased with age. Specifically, patients ≥80 years old had higher rates of comorbidities and experienced the highest rates of ischaemic and bleeding complications compared to younger patients, even after adjusting for confounding factors. The study concluded that elderly STEMI patients, especially those ≥80 years old, are a high-risk group that requires individualized therapy to optimize clinical outcomes.
Risk factors for adverse coutcomes
This study analyzed data from over 30,000 patients with heart failure (HF) to identify predictors of adverse outcomes based on left ventricular ejection fraction (LVEF). Patients were categorized as having preserved LVEF (≥50%), borderline LVEF (41-49%), or reduced LVEF (≤40%). Over a median follow up of 1.8 years, 26.8% of patients died, 26.9% were hospitalized for HF, and 67.4% were hospitalized for any reason. Multivariable models found that nearly all tested predictors, such as demographics, medical history, and comorbidities, performed similarly for predicting death and hospitalization across the different LVEF
Novel Method for Automated Analysis of Retinal Images: Results in Subjects wi...
Michele Cavallari, Claudio Stamile, Renato Umeton, Francesco Calimeri, and Francesco Orzi
Morphological analysis of the retinal vessels by fundoscopy provides noninvasive means for detecting and staging systemic microvascular damage. However, full exploitation of fundoscopy in clinical settings is limited by paucity of quantitative, objective information obtainable through the observer-driven evaluations currently employed in routine practice. Here, we report on the development of a semiautomated, computer-based method to assess retinal vessel morphology. The method allows simultaneous and operator-independent quantitative assessment of arteriole-to-venule ratio, tortuosity index, and mean fractal dimension. The method was implemented in two conditions known for being associated with retinal vessel changes: hypertensive retinopathy and Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL). The results showed that our approach is effective in detecting and quantifying the retinal vessel abnormalities. Arteriole-to-venule ratio, tortuosity index, and mean fractal dimension were altered in the subjects with hypertensive retinopathy or CADASIL with respect to age- and gender-matched controls. The interrater reliability was excellent for all the three indices (intraclass correlation coefficient ≥ 85%). The method represents simple and highly reproducible means for discriminating pathological conditions characterized by morphological changes of retinal vessels. The advantages of our method include simultaneous and operator-independent assessment of different parameters and improved reliability of the measurements.
The Effect of Demographic Data and Hemoglobin A 1c on Treatment Outcomes in P...
Objective: Diabetes mellitus, the most common cause of non-traumatic foot amputations, is a life-threatening condition due to its high mortality and morbidity. In our study, we retrospectively evaluated our patients with diabetic foot syndrome in our clinic. Materials and Methods: The demographic data, duration of diabetes, Wagner classification, haemoglobin A 1c (HbA1c) levels, white blood cell, C-reactive protein sedimentation levels, hospital stay, and treatment results were evaluated retrospectively in 14 patients with diabetic foot between January 2017 and December 2018. Results: The mean age of the patients was 62.43 ± 7.7 years. Of the 14 patients, 3 were females and 11 were males. All 14 patients were type 2 diabetes mellitus. When diabetic foot Wagner classification was performed, 6 patients were evaluated as Wagner 2, five patients were Wagner 3, and three patients were evaluated as Wagner 4. Nine patients had complete amputation and 3 had vascular surgery. Conclusion: Although the level of HbA1c is below the target level, the risk of diabetic foot is increased when there is no adequate diabetes mellitus foot training. Inadequate diabetic patient education and hospitalization of patients after infection progress the amputation rate.
Seattle heart failure model
The Seattle Heart Failure Model was developed by researchers at the University of Washington to accurately predict 1, 2, and 3-year survival rates for patients with heart failure based on simple clinical variables. The model also estimates how a patient's survival would be impacted by various heart failure medications and devices. Validation testing found the model provided excellent accuracy. It is available online and allows clinicians to estimate how adding different treatment options could extend a patient's predicted lifespan. The researchers hope this model will encourage both patients and doctors to more frequently use proven life-saving heart failure medications and devices.
HEC 2014 / James Peake: The Quality Journey of the U.S. Department of Veteran...
HEC 2014 / James Peake: The Quality Journey of the U.S. Department of Veteran...Ahjo Communications Oy
The presentation Dr. James Peake gave in the Healthcare Executive Circle 2014 -seminar in 6th of February, 2014.
http://hec2014.fi/Differences in clinical characteristics and its effect for outcomes
The document summarizes differences in characteristics and outcomes between Western and Korean patients with acute heart failure based on an analysis of registry data. It finds that compared to Western registries, Korean patients tended to be relatively younger (mean age 69 years old), with a higher rate of first-time heart failure presentations (52.1%) and lower rates of hypertension and coronary artery disease as the cause of heart failure. Korean patients also presented with lower blood pressures on admission. In-hospital mortality rates were similar at around 5%, though Korean patients had lower 90-day mortality. Factors like creatinine levels, blood pressure, BMI and sodium levels similarly predicted outcomes. Rates of beta blocker use at discharge were also lower for Korean
Ischemia Trial
The document reports on a study from the ISCHEMIA trial investigating the impact of complete versus incomplete revascularization on clinical outcomes in patients with stable ischemic heart disease treated with an invasive versus conservative strategy. It finds that among patients treated with an invasive strategy, complete anatomic or functional revascularization was associated with improved outcomes compared to incomplete revascularization. However, after adjustment for covariates, the differences in outcomes between complete and incomplete revascularization were no longer statistically significant.
Stopdapt 2 randomized clinical trial
the 1-year cumulative incidence of a composite end point consisting of cardiovascular death, myocardial infarction, ischemic or hemorrhagic stroke, definite stent thrombosis, and major bleeding was 2.4% in the 1-month DAPT group and 3.7% in the 12-month DAPT group, a difference that met the noninferiority margin of a hazard ratio of 0.5, as well as superiority.
What's hot (20)
Thierry Chassaulet: Predictive risk modelling: Does technique or time matter?
Thierry Chassaulet: Predictive risk modelling: Does technique or time matter?
Measuring long term effect of Telecare on Chronic Diseases by Masatugu Tsuji,
Measuring long term effect of Telecare on Chronic Diseases by Masatugu Tsuji,
Outcomes of Carotid Stent Systems Versus Endarterectomy 4.29.08
Outcomes of Carotid Stent Systems Versus Endarterectomy 4.29.08
Aspirin as Prevention Therapy for Cardiovascular Events in patients with Diab...
Aspirin as Prevention Therapy for Cardiovascular Events in patients with Diab...
Central Adiposity and Mortality after First-Ever Acute Ischemic Stroke
Central Adiposity and Mortality after First-Ever Acute Ischemic Stroke
Critical Illness Outcomes in General Versus Specialty Intensive Care Units 5....
Critical Illness Outcomes in General Versus Specialty Intensive Care Units 5....
Novel Method for Automated Analysis of Retinal Images: Results in Subjects wi...
Novel Method for Automated Analysis of Retinal Images: Results in Subjects wi...
The Effect of Demographic Data and Hemoglobin A 1c on Treatment Outcomes in P...
The Effect of Demographic Data and Hemoglobin A 1c on Treatment Outcomes in P...
HEC 2014 / James Peake: The Quality Journey of the U.S. Department of Veteran...
HEC 2014 / James Peake: The Quality Journey of the U.S. Department of Veteran...
Differences in clinical characteristics and its effect for outcomes
Differences in clinical characteristics and its effect for outcomes
Viewers also liked
204 prevalence of inflammatory cells in non ruptured atherosclerotic plaques
This document summarizes a post-mortem study examining the prevalence of inflammatory cells in non-ruptured atherosclerotic plaques. The study found that moderate or heavy staining for macrophages was present in 45% of femoral artery cross-sections and 84% of femoral arteries had at least one cross-section with moderate/heavy inflammation. There was no observed relationship between the degree of inflammation in the left and right coronary arteries within individuals, indicating the level of local inflammation is locally determined with little predictive value for other arteries.
048 adventitial fat presentation
1) The study investigated the uptake of SPIO (superparamagnetic iron oxide), an MRI contrast agent, by periadventitial fat in an atherosclerosis mouse model.
2) Results showed significantly greater uptake of iron in the periadventitial fat of apoE k/o mice compared to control mice, as measured by iron particles and area.
3) Preliminary evidence also suggests uptake of iron in the periadventitial fat of atherosclerotic rabbits and humans, suggesting macrophage-like activity in this tissue that warrants further investigation into its role in atherosclerosis and potential applications for plaque imaging.
225 animal models of heart attack part 2
I. This document discusses various animal models that have been used to study atherosclerosis and plaque rupture, including quail, pigeons, chickens, dogs, monkeys, pigs, rats, rabbits, and mice. It provides details on the types of lesions developed and similarities to human disease for each model.
II. The double knockout LDL/apoE mice are highlighted as offering improvements in studying clinical complications of atherosclerosis like human heart disease. However, it is unclear how closely they model vulnerable plaques.
III. Questions are raised about how closely the coagulation systems of these animal models resemble humans and whether any model fully captures repeated plaque ruptures and the role of aging in natural history as seen in humans.
120 mr imaging for the evaluation of carotid atherosclerosis
This document discusses the use of MR imaging to evaluate carotid atherosclerosis. It notes that MR imaging can provide high-resolution images of carotid plaque geometry and composition in vivo, capturing details like fibrous caps and necrotic cores. The document outlines different MR imaging techniques for evaluating carotid arteries, such as high-resolution TOF-MRA, CE-MRA, and T2-weighted imaging. It presents examples of images showing lumen contours, calcification, and plaque components visualized with these methods. The document suggests that improved MR imaging techniques may help identify features of carotid plaque that are associated with rapid progression and neurological risk.
213 oral apo ai mimetic peptide for reduction of atherosclerosis
I. The document discusses studies on the effects of oral administration of apolipoprotein A-I mimetic peptides synthesized from D-amino acids in reducing atherosclerosis in mice. It was found to dramatically decrease lesions by 75-79% independent of changes in total or HDL cholesterol.
II. The peptide is proposed to be useful for preventing and treating atherosclerosis and other inflammatory diseases caused by oxidized lipids. Its ability to reduce lesions orally suggests potential as a therapeutic agent.
III. Further studies are referenced that examine the mechanisms of action of apo A-I and analogs in protecting against atherosclerosis through reverse cholesterol transport and removal of oxidized lipids.
108 cetp expression
CETP overexpression in diabetic and obese db/db mice prevented the formation of diet-induced atherosclerotic plaques in the aorta. CETP overexpression lowered total cholesterol concentrations and reduced cholesterol levels in the pro-atherogenic VLDL and IDL/LDL lipoprotein subfractions. This suggests CETP plays an anti-atherogenic role in the context of diabetic obesity by modifying cholesterol distribution among lipoproteins. The authors conclude CETP may help maintain vascular health in humans with diabetic obesity, and its suppression in this population may contribute to higher atherosclerosis risk.
185 towards the future cath lab
This document discusses the potential for using MRI as an alternative to x-ray guidance in cardiac catheterization labs and interventional procedures. It outlines the history of MRI in cardiovascular imaging and interventions. Recent studies are presented that demonstrate the feasibility of MRI-guided coronary catheterization and balloon angioplasty. However, technological barriers around making equipment MRI-compatible as well as accreditation and reimbursement issues still need to be addressed before MRI could fully replace x-ray systems in cath labs. The combination of x-ray and MRI into a single "XMR" system may be a viable solution.
125 ct based characterization
Growing evidence suggests that CT-based characterization of coronary plaques and arteries is possible. 16 slice multi-detector CT can reliably detect coronary obstructions when combined with heart rate control. It can also identify soft, intermediate, and calcified plaques. This technology has great potential as an initial non-invasive technique to identify vulnerable plaque or arteries in at-risk populations. The combination of CT imaging with serum markers may provide a powerful predictive tool for assessing vulnerability.
034 everybody has atherosclerosis
This document discusses a non-invasive technique using superparamagnetic iron oxide (SPIO) enhanced MRI to detect vulnerable plaque. SPIO particles are phagocytosed by macrophages and can thus be used to image inflammation. Studies in mice showed SPIO accumulation in atherosclerotic plaques after intravenous injection, indicating macrophage infiltration. MRI of abdominal aortas of mice after SPIO injection demonstrated higher signal in plaques compared to normal vessel walls, corresponding to greater iron uptake in inflamed plaques. This suggests SPIO enhanced MRI may non-invasively detect vulnerable plaque by imaging macrophage-mediated inflammation.
No correlation and low agreement of imaging and inflammatory atherosclerosis’...
Presented by:
Lilton R.C. Martinez MD, Marcio H. Miname MD, Luiz A. Bortolotto MD, Ana P.M. Chacra MD, Carlos E. Rochitte MD, Andrei C. Sposito MD, Raul D. Santos MD,PhD.
117 mr images of human carotid arteries
Magnetic resonance (MR) images were taken of human carotid arteries from both a normal subject and a patient with carotid artery disease. The images show the carotid arteries of a healthy individual for comparison with those of a person suffering from carotid artery disease. The diseased arteries likely demonstrate abnormalities that indicate a restriction of blood flow.
134 mr contrast agents for vulnerable plaque imaging
1. MS-325 is an albumin-targeted gadolinium contrast agent that highlights inflamed vessel walls and facilitates plaque imaging. It provides prolonged enhancement of the vessel wall and lumen, allowing for high resolution detection of plaque burden.
2. Studies show MS-325 provides strong enhancement of vessel walls adjacent to plaques due to increased capillary volume and binding to extravasated albumin in the vessel wall. This allows for detection and potential quantification of atherosclerotic plaques.
3. Experimental fibrin-targeted contrast agents EP-1242 and EP-1873 rapidly enhance arterial and venous blood clots in animal models, demonstrating potential for assessing thromboembolic risk and monitoring clot resolution with
089 intravascular magnetic resonance imaging
Intravascular magnetic resonance imaging uses small coils placed inside blood vessels to provide both active tracking of devices and high resolution diagnostic imaging. Two types of intravascular coils - loopless and loop designs - can generate very high signal locally for imaging vessel structures with resolutions as small as 60-200 micrometers. This technique has been demonstrated to image vessels in animal models and humans with better resolution than external coils. Further developments are needed but intravascular MRI shows promise for guiding cardiovascular interventions and precisely localizing devices under MRI guidance.
257 inhibition of atherosclerosis in mice
This document discusses research into identifying immune responses against oxidized LDL in humans and developing an immunization therapy to inhibit atherosclerosis. The research found that immunization of apoE null mice with specific MDA-modified apoB-100 peptide sequences activated athero-protective immune responses and significantly reduced atherosclerotic plaque development compared to controls. This suggests vaccination with these peptide sequences may be a potential therapy for atherosclerosis by stimulating protective immune responses against oxidized LDL.
144 physics of mri
A 71-year-old man with a history of diabetes, coronary artery disease status post myocardial infarction times three, and hypercholesterolemia was found to have an accidental left carotid stenosis and was scheduled for a left carotid endarterectomy. MRI of the carotid arteries was performed using SPIO contrast to better evaluate the extent of disease prior to surgery.
253 endothelial dysfunction
1. Isolated-low HDL levels in ABCA1 heterozygotes is associated with impaired basal and stimulated endothelial nitric oxide synthase activity.
2. A single rapid infusion of reconstituted HDL completely restored both basal and stimulated endothelial nitric oxide synthase activity in ABCA1 heterozygotes.
3. Impaired lipid trafficking and caveolar disruption caused by dysfunctional ABCA1 profoundly affects endothelial nitric oxide synthase activity.
3rd vulnerable plaque rumberger 3 16-02 3
1) Clinical data confirms that coronary calcium detected by electron beam computed tomography (EBT) is found in 96% of patients presenting with or developing acute coronary syndromes, and that these patients have significantly greater coronary artery calcium scores at baseline compared to asymptomatic matched individuals.
2) Histologic studies show that coronary artery calcium occurs in all types of plaques, including stable (43%), rupture-prone (54%), and erosion-prone (77%) plaques.
3) Therefore, coronary artery calcium detected by imaging is a marker of atherosclerotic plaque burden but not necessarily a marker of stable or unstable plaque, as there is considerable overlap in calcium presence between different plaque types.
230 plaque crp or myocardial crp
This document summarizes research on C-reactive protein (CRP) and its relationship to atherosclerosis and coronary death. It finds that CRP levels are elevated in patients with unstable angina and predict future cardiovascular risk. A study of sudden coronary deaths found higher CRP levels in those who died from plaque rupture compared to controls or those who died from stable plaques or erosion. The study also observed a positive correlation between CRP staining in atherosclerotic plaques and serum CRP levels, independent of the death mechanism. However, questions remain about how well postmortem CRP correlates with pre-death levels and the extent to which elevated CRP results from cardiac injury rather than reflecting the plaque vulnerability.
219 coronary autoregulation in vivo
This study investigated the role of hydrogen peroxide as an endogenous EDHF in coronary autoregulation of canine subepicardial microvessels in vivo. The researchers found that after NO inhibition, vasodilator responses were attenuated mainly in small arteries (>100 μm), whereas combined infusion of NO inhibition plus catalase abolished the autoregulatory vasodilation in both small arteries and arterioles (<100 μm). They concluded that hydrogen peroxide, an endogenous EDHF, plays an important role in coronary autoregulation of canine subepicardial microvessels in vivo.
249 the most cost effective therapy
This document summarizes research on the effectiveness and cost-effectiveness of influenza vaccination, statin drugs, and aspirin for preventing cardiovascular events. It finds that influenza vaccination has been shown to reduce hospitalizations for cardiovascular disease by 6-12% and lower mortality by 48-50% based on observational studies. The cost per life saved from influenza vaccination is estimated to be $13,200, much lower than the $198,000 per life saved by statin drugs. While statins and aspirin are effective therapies, influenza vaccination provides benefits to cardiovascular health at the population level due to its low cost and ability to prevent thousands of events each year. More research is still needed to understand the mechanisms by which influenza increases cardiovascular risk
Viewers also liked (20)
204 prevalence of inflammatory cells in non ruptured atherosclerotic plaques
204 prevalence of inflammatory cells in non ruptured atherosclerotic plaques
120 mr imaging for the evaluation of carotid atherosclerosis
120 mr imaging for the evaluation of carotid atherosclerosis
213 oral apo ai mimetic peptide for reduction of atherosclerosis
213 oral apo ai mimetic peptide for reduction of atherosclerosis
No correlation and low agreement of imaging and inflammatory atherosclerosis’...
No correlation and low agreement of imaging and inflammatory atherosclerosis’...
134 mr contrast agents for vulnerable plaque imaging
134 mr contrast agents for vulnerable plaque imaging
Similar to Coronary artery disease among asymptomatic diabetic and non-diabetic patients undergoing coronary CT angiography
Ueda 2016 dm & cad-amr el hadidy
This document discusses screening for coronary artery disease (CAD) in asymptomatic patients with diabetes. It notes that while CAD risk is elevated in diabetic patients, widespread screening is not currently recommended due to a lack of evidence that it improves outcomes. Some key points made in the document:
- The risk of CAD is higher and often silent in diabetic patients. However, screening the large number of diabetic patients is very costly, and it is unclear if treating silent CAD found on screening would actually help patients.
- Two studies found that screening stress SPECT imaging found abnormal results in only 16-17% of asymptomatic diabetic patients.
- More data is still needed to determine if screening can identify a high-risk group of diabetic patients
Screening for asymptomatic cad in diabetes
Diabetes is a growing global health problem, affecting over 246 million people worldwide. Cardiovascular disease is a major cause of death for those with diabetes. While diabetes itself increases the risk of cardiovascular events, controlling individual risk factors can help prevent related complications. There is ongoing debate around screening asymptomatic diabetic patients for coronary artery disease. Supporters argue early detection could improve outcomes, but critics note current tests are not perfect and may lead to unnecessary invasive procedures. Further research is still needed to identify high-risk groups who could benefit most from screening.
Clinical Profile of Patients with Coronary Tortuosity and its Relation with C...
Coronary tortuosity is a common angiographic finding. This study was done to observe the clinical profile of patients with coronary tortuosity (CT) and its relation with coronary artery disease (CAD). Method: A total 224 patients undergoing angiography for suspected CAD were included in the study. Coronary tortuosity was defined by the presence of ≥3 consecutive bends of > 45 degree, measured at end-diastole in an epicardial artery ≥2 mm in diameter. Coronary tortuosity was present in 45(20.1%) patients (CT group) in the study and another 45 patients without coronary tortuosity was randomly selected as control (NCT group). Clinical profile of CT and NCT group was compared. Results: Incidence of coronary tortuosity was significantly higher in females (p=0.000) and hypertensives (p=0.001) patients. Coronary tortuosity was most commonly seen in Left circumflex coronary artery. Incidence of CAD was significantly lower in CT group as compare to NCT group (0.02). Risk factors for CAD was associated with reduced incidence of Coronary tortuosity. Majority (88.5%) patient with CT without CAD presented with chronic stable angina out of which (65.2%) had an objective evidence of myocardial ischemia. Conclusion: Coronary tortuosity is more commonly seen females and hypertensive patients. It has negative correlation with CAD but can lead to myocardial ischemia. Risk factors of CAD do not predict CT.
Racial Differences in Access to New Technology 4.29.08
This document summarizes a study that analyzed Medicare claims data to compare rates of carotid stent placement (CSS) versus carotid endarterectomy (CE) among white and black patients from 2005-2006. The study found no evidence of racial differences in receiving CSS in the initial period of Medicare coverage. A logistic regression model controlling for patient and hospital characteristics found black patients had similar odds of receiving CSS compared to whites. Additional models found no significant interaction between patient race and geographic variability in CSS utilization rates.
Diabetic kidney disease 2021
Update on diabetic kidney disease given at the New Mexico Academy of Physician Assistant Conference on 9/23
Trends in diabetes-related health indicators in Aboriginal communities in Nor...
2010 University of Alberta - School of Internal Medicine Research Day, poster presentation by Richard Oster (BRAID Research)
Predictors of persistence with antihypertensive therapy: results from the NHANES
This study evaluated factors that affect persistence with antihypertensive medication use using data from several NHANES surveys. It found that non-persistence was higher in younger patients, men, and Hispanics. Financial barriers like low income, lack of health insurance, and not visiting a doctor in the past year significantly increased non-persistence, accounting for over 50% of cases. Improving access to healthcare and follow-up may help maintain long-term persistence with hypertension medication.
Stable angina
Coronary heart disease is best addressed by a comprehensive approach aimed at halting atherosclerotic disease and reducing the risk of thrombosis. Unfortunately, our success in optimal risk factor modification in patients with stable CHD remains poor: only 41% of patients achieved all basic goals in the recent ISCHEMIA trial, with success rates likely even lower outside the rigorous clinical trial context. A greater focus on achieving prevention goals in patients with CHD will have a substantial impact on patient outcome and rates of hospitalization and more resources and incentives should be allocated for improved secondary prevention.
The ISCHEMIA trial suggests that even selected, high-risk patients with extensive ischemic burden do not benefit from revascularization barring unacceptable angina despite OMT. As ISCHEMIA excluded patients with unacceptable angina, advanced heart failure, and those with unprotected left main disease, our evaluation may be geared to identify such patients for consideration of revascularization alongside an initial strategy of OMT.
Atherosclerosis is a systemic disease of the arterial circulation, with focal areas of more severe manifestation. From an imaging standpoint, the paradigm of ischemia testing may have come to an end. Recent evidence from COURAGE, PROMISE, SCOT-HEART, and ISCHEMIA has demonstrated that functional testing for inducible myocardial ischemia is inferior to anatomic assessment for risk stratifying and managing patients with suspected or known CHD. Consistent with a large body of evidence, risk from CHD is mediated by the extent of atherosclerotic disease burden and not by the extent of inducible ischemia. Given that 55% of patients had nonobstructive CHD by CT in PROMISE, which was associated with 77% of cardiovascular deaths and myocardial infarctions at follow-up, there is immense opportunity to impact the disease at an earlier stage in a very large population of patients with occult CHD.
Objetivos en diabetes: de la "evidencia" al sentido común
Objetivos en diabetes: de la "evidencia" al sentido común
José Manuel Millaruelo Trillo. Centro de Salud Torrero La Paz. Zaragoza. Miembro de la red GEDAPS Aragón
Hypertension and Diabetic Kidney Disease Progression Hypertension and Diabe...
Hypertension and diabetic kidney disease progression are linked, and reducing proteinuria is key to slowing kidney disease. The document discusses how conditions like hypertension and diabetes that cause kidney damage have increased in the US population. Landmark trials found that lowering blood pressure and proteinuria reduced kidney disease progression and cardiovascular risks. Initial therapy for kidney or diabetes patients should be an ACE inhibitor or ARB to target blood pressure under 130/80 mmHg.
Diabetes Care
This study analyzed cardiovascular risk factor control among 3,769 veterans with diabetes receiving care from VA medical centers. It found that optimal control of factors like blood sugar, blood pressure, and cholesterol was uncommon. While veterans with heart disease were more likely to have their blood pressure and cholesterol controlled, control rates remained low overall, suggesting more aggressive management is needed, especially for those without heart disease.
Cardiovascular.pptx slide for detection cancer
The document discusses cardiovascular disease and summarizes previous work done on the topic. It provides an introduction to cardiovascular disease, describes common types like coronary artery disease and heart failure. It outlines risk factors and symptoms. The document also summarizes several previous studies that examined relationships between biomarkers and cardiovascular risk, impacts of fitness and genetics, machine learning methods for prediction, and connections between COVID-19 and heart conditions. It provides details on the dataset and preprocessing steps used, including cleaning, feature engineering, and outlier handling. The results of running several machine learning algorithms on the data are presented.
BP Targets-where are we now.pptx
This document discusses hypertension guidelines and management. It covers the epidemiology of hypertension, guidelines for classification and treatment targets, detection of white coat and masked hypertension, and management of hypertension in patients with comorbidities like chronic kidney disease. Proper control of hypertension is important for reducing cardiovascular and renal risks. Treatment involves lifestyle changes and antihypertensive medications, with certain drugs offering additional organ protective effects. Management is more complex in patients on dialysis or after kidney transplantation.
clopidogril and ACS
- Polyvascular disease, where a patient has atherosclerosis in more than one vascular bed (e.g. coronary, carotid, and peripheral arteries) is common, with around 25-60% of patients with disease in one bed also having it in others.
- Patients with polyvascular disease have higher rates of cardiovascular events than those with single-bed disease.
- Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor such as clopidogrel or ticagrelor is frequently used long-term or lifelong in patients with polyvascular disease to reduce the risk of future cardiovascular events.
Hyvet Slide Set
The document summarizes the results of the HYVET trial, which provided the first clear evidence for treating hypertension in patients aged 80 or over. The trial found that treating hypertensive patients aged 80 or over with the Natrilix SR-based regimen reduced total mortality by 21%, all strokes by 30%, fatal strokes by 39%, and heart failure by 64% compared to placebo. The treatment was also well-tolerated with few serious adverse events reported.
A STUDY ON PREVALENCE OF MICRO AND MACRO VASCULAR COMPLICATIONS IN TYPE 2 DI...
This study examined the prevalence of microvascular and macrovascular complications in 1200 patients with type 2 diabetes in India. Retinopathy was found in 13.5% of patients, nephropathy in 26%, neuropathy in 31.5%, cardiovascular disease in 19.1%, and peripheral vascular disease in 9.75%. Logistic regression revealed that older age, longer diabetes duration, and hypertension were significantly associated with all complications. Poor glycemic control was associated with higher rates of nephropathy and retinopathy. The study highlights the high prevalence of complications, especially nephropathy and neuropathy, in this population.
Ndei Cardiovascular Disease In Diabetes Epidemiology
These slides and hundreds more are available for download from www.ndei.org.
Both registration and downloads are free.
Sympo.grandes.etudes.algerie.2020.version.04.ppt
PRESENTATION QUI REGROUPE LES DIFFERENTS ETUDES SUR HTA DEPUIS 2010 A 2020 :
- Acute Severe Hypertension
-Comprehensive Comparative Effectiveness and Safety of First-Line Antihypertensive Drug Classes: A Systematic, Multinational, Large-Scale Analysis
-Retinal Vessel Calibers in Predicting Long-Term Cardiovascular Outcomes The Atherosclerosis Risk in Communities Study
-ACC/AHA Versus ESC/ESH on Hypertension Guidelines
JACC Guideline Comparison
-Age at Diagnosis of Type 2 Diabetes Mellitus and Associations With Cardiovascular and Mortality Risks Findings From the Swedish National Diabetes Registry
-
The Science Diabetes Control
The document discusses diabetes, including the different types of diabetes, risk factors, complications, and findings from major clinical trials on diabetes control and treatment. It summarizes results from studies like the Diabetes Control and Complications Trial (DCCT) and United Kingdom Prospective Diabetes Study (UKPDS) which showed that intensive glucose control can reduce diabetes complications. More recent trials found benefits but also risks of intensive control, depending on individual patient factors. The National Diabetes Education Program (NDEP) provides public education materials on diabetes control and management.
Stable ischemic heart disease how is it different from acs..
Lecture presented by Dr. Dev Pahlajani at the ACS Conference on Stable Ischemia Heart Disease, Mumbai, 2015
Similar to Coronary artery disease among asymptomatic diabetic and non-diabetic patients undergoing coronary CT angiography (20)
Clinical Profile of Patients with Coronary Tortuosity and its Relation with C...
Clinical Profile of Patients with Coronary Tortuosity and its Relation with C...
Racial Differences in Access to New Technology 4.29.08
Racial Differences in Access to New Technology 4.29.08
Trends in diabetes-related health indicators in Aboriginal communities in Nor...
Trends in diabetes-related health indicators in Aboriginal communities in Nor...
Predictors of persistence with antihypertensive therapy: results from the NHANES
Predictors of persistence with antihypertensive therapy: results from the NHANES
Objetivos en diabetes: de la "evidencia" al sentido común
Objetivos en diabetes: de la "evidencia" al sentido común
Hypertension and Diabetic Kidney Disease Progression Hypertension and Diabe...
Hypertension and Diabetic Kidney Disease Progression Hypertension and Diabe...
A STUDY ON PREVALENCE OF MICRO AND MACRO VASCULAR COMPLICATIONS IN TYPE 2 DI...
A STUDY ON PREVALENCE OF MICRO AND MACRO VASCULAR COMPLICATIONS IN TYPE 2 DI...
Ndei Cardiovascular Disease In Diabetes Epidemiology
Ndei Cardiovascular Disease In Diabetes Epidemiology
Stable ischemic heart disease how is it different from acs..
Stable ischemic heart disease how is it different from acs..
More from SHAPE Society
Barth imt
This document provides background on Jacques Barth, an expert in cardiovascular imaging and risk assessment. It discusses the evolution of ultrasound technology for measuring intima-media thickness (IMT) from 1986 to 2005. IMT is an early marker of atherosclerosis and cardiovascular risk. The document also addresses issues around vulnerable plaques, reporting IMT measurements, and assessing cardiovascular risk in children and adolescents.
Braunwald
This document outlines an approach to identifying and managing coronary risk. It recommends that prevention must be the primary goal through intensive global risk factor reduction for all patients with clinically apparent heart disease. It also recommends identifying asymptomatic high-risk individuals through testing like the Framingham Risk Score so they can receive prevention. It proposes a risk stratification approach from low to very high risk based on annual risk levels and corresponding testing and treatments, with very high risk patients receiving the most intensive treatments like invasive detection of unstable plaques and procedures like CABG or multiple drug-eluting stents.
Acc vp-org 3-02 stone
This document describes a study that uses intravascular ultrasound (IVUS), biplane coronary angiography, and blood flow measurements to characterize endothelial shear stress (ESS) in coronary arteries. It found that over 6 months, areas of low ESS demonstrated plaque progression, areas of normal ESS remained stable, and areas of high ESS developed outward remodeling. The technology allows in vivo determination of intracoronary flow velocity and ESS, which has not previously been possible. This provides a method to predict progression of atherosclerosis and vascular remodeling. A pilot study applied this technique in 8 patients at baseline and 6 months to analyze changes in native coronary artery disease and in-stent restenosis while taking candesartan vs fel
101205 shape aha 2005 f
Zahi A. Fayad is an Associate Professor who studies molecular imaging of atherosclerosis using MRI. His research focuses on developing targeted contrast agents to noninvasively detect unstable plaque. Some agents under investigation include annexin A5 labeled with a radioisotope to detect apoptosis, FDG-PET to assess plaque activity, and fibrin-targeted and MMP-targeting Gd-based contrasts. Additional work involves lipid-based particulate agents using reconstituted HDL or iron oxide nanoparticles. The goal is to improve MRI detection sensitivity and specificity for high-risk plaque characterization.
Acc v porg becker
This document discusses the use of coronary CT angiography (CTA) to detect and characterize coronary atherosclerosis beyond just detecting coronary stenoses. CTA can identify calcified plaques, non-calcified plaques, mixed plaques, atheromas, thrombi, and myocardial infarction scars. CTA provides information on plaque composition and distribution that can help understand coronary artery disease and be used to follow patients under therapy. The limitations of CTA include artifacts from cardiac motion, breathing, blooming effect, and poor contrast opacification of small vessels. Advances in multislice CT technology are helping to address some of these limitations.
Acc 2005-1, v pl-vp
This document discusses approaches to cardiovascular disease (CVD) and the need for new approaches. It summarizes that the emphasis is shifting from high risk plaques to high risk symptomatic patients, and from high risk asymptomatic to intermediate and low risk patients. It discusses diagnostic tools like magnetic resonance imaging to identify high risk asymptomatic patients and computed tomography to identify intermediate risk patients using coronary artery calcium scoring and CRP biomarkers. It also discusses prevention and treatment strategies like a polypill for acute coronary syndrome patients and those with chronic atherothrombosis.
Acc presentation macrophage (1)
This document proposes a non-invasive method using SPIO (super paramagnetic iron oxide) nanoparticles to image macrophage infiltration and inflammation in vulnerable atherosclerotic plaques. Rabbits and mice were injected with SPIO, which accumulated in inflamed plaque areas correlated with macrophage density. SPIO-enhanced MRI then successfully identified these inflamed plaques non-invasively in vivo. This technique could provide a way to detect rupture-prone plaques and better understand plaque vulnerability.
Acc v porg
This document discusses the use of coronary CT angiography (CTA) to detect and characterize coronary atherosclerosis beyond just detecting coronary stenoses. CTA can identify calcified plaques, non-calcified plaques, and mixed plaques. It can detect atheromas and characterize plaque density. CTA can also identify intracoronary thrombi and myocardial infarction scars. The document outlines the CTA scanning parameters and techniques used to minimize motion artifacts and optimize image quality for plaque detection and characterization.
Acc presentation (1)
This document describes a study that introduces a non-invasive method for imaging macrophage infiltration in inflamed atherosclerotic plaques using superparamagnetic iron oxide (SPIO) nanoparticles and MRI. The researchers injected SPIO into hypercholesterolemic and normal rabbits and found that SPIO profoundly accumulated in areas of macrophage infiltration in the atherosclerotic plaques, as confirmed by histology. SPIO-enhanced MRI was able to identify these inflamed plaques non-invasively. The results suggest SPIO-enhanced MRI can be a novel method for detecting rupture-prone inflamed plaques associated with heart attacks and strokes.
Ac cculprit
The document discusses several factors that are considered predictors of plaque vulnerability, including luminal narrowing, plaque volume and composition, fibrous cap thickness, and plaque inflammation. It reviews studies that show myocardial infarction can develop from previously non-severe lesions and that lipid content, cap thickness, inflammation, and stress factors like circumferential stress are correlated with plaque stability and vulnerability. In conclusion, the size and composition of the lipid core, thickness and composition of the fibrous cap, and inflammation are well-established predictors of plaque rupture.
Acc presentation lipid coated(2)
This document discusses a novel tracer for MRI imaging of macrophage infiltration in atherosclerotic plaque. It summarizes research into lipid-coated superparamagnetic iron oxide nanoparticles (SPIOs) that are phagocytosed by macrophages. The researchers tested various SPIO coatings and sizes to maximize macrophage uptake while minimizing oxidative stress. Lipid-coated SPIOs combined with certain aminoglycans showed the highest uptake and lowest induction of reactive oxygen species. The goal is to develop an MRI contrast agent that can noninvasively image vulnerable, inflamed plaques by detecting macrophage presence.
Acc 2002 microarray mehran for print
This document discusses the use of DNA microarrays in vulnerable plaque research. It provides background on atherosclerosis and identifies DNA microarrays as a tool that can be used to investigate the molecular mechanisms underlying plaque vulnerability. The document outlines the basic steps of a DNA microarray experiment and discusses considerations for experimental design, data analysis, and validation of results. It also summarizes several studies that have used DNA microarrays or related techniques to examine gene expression in atherosclerosis.
Acc booth inventory
The document provides details about AEHA's booth at the ACC/AEHA Exhibition from March 30 to April 1, 2003. It lists the booth equipment and inventory, proposed activities like an Ecode on Friday morning and a VP Symposium. Giveaways include Magellan GPS devices in a raffle and Dove chocolates. It also discusses the need for an immediate membership sign-up page on the AEHA website and a vision for the future of AEHA.
Acc 04 vuln pt
This document discusses approaches to identifying and managing coronary risk. It states that the primary goal should be preventing acute cardiac events through intensive risk factor reduction for all patients with clinically apparent heart disease. Additionally, it notes that one third of sudden cardiac deaths and heart attacks occur in previously asymptomatic individuals with undiagnosed risk factors or pre-clinical disease. The document proposes identifying high-risk asymptomatic individuals through testing to provide prevention. It presents a risk stratification approach using testing like CRP, cholesterol, glucose and imaging to guide different levels of risk factor reduction and management.
Acc 2002 mehran for print
This document discusses the use of DNA microarrays in studying vulnerable atherosclerotic plaques. It provides background on atherosclerosis and plaque rupture. DNA microarrays allow high-throughput analysis of gene and protein expression, which can provide insights into molecular mechanisms underlying plaque vulnerability. One study used microarrays to analyze gene expression differences between ruptured and stable plaques, identifying perilipin as upregulated in ruptured plaques. However, microarray analysis of atherosclerosis is still in its early stages with many technical challenges to address.
Acc2002 thermography
Vulnerable plaques are prone to rupture and cause heart attacks. This document proposes criteria for defining vulnerable plaques based on histopathology and clinical factors. It also explores using infrared thermography to identify vulnerable plaques by detecting heat from macrophage inflammation. Studies in animal models and humans found temperature heterogeneity in atherosclerotic arteries that correlated with plaque vulnerability features. Further research aims to develop non-invasive thermography techniques to accurately detect vulnerable plaques and help predict heart attack risk.
A20 gene
The document presents findings on the A20 gene, which encodes a zinc finger protein that inhibits NF-kB activity and TNF-induced apoptosis. The study found that C57 and FVB mouse strains have a coding difference in A20 that generates a phosphorylation site in C57 mice. C57-A20 was less effective at shutting down TNF-induced NF-kB activity and C57 cells were less susceptible to TNF-induced apoptosis compared to FVB cells. This suggests less active A20 in C57 mice leads to increased inflammation and reduced apoptosis, while more active A20 in FVB mice decreases inflammation and increases apoptosis, contributing to differences in atherosclerosis susceptibility between the strains.
#1 killer of human beings in the 21st century
Vulnerable plaque refers to dangerous forms of atherosclerotic plaques that can rupture or induce thrombosis, disrupting blood flow. The document discusses the history and research around vulnerable plaque, including pioneers in the field and emerging techniques to detect vulnerable plaque such as intravascular ultrasound, optical coherence tomography, and magnetic resonance imaging. It summarizes that vulnerable plaques are typically characterized by a thin fibrous cap, large lipid core, and presence of macrophages.
A20 is an atherosclerosis
The document presents findings on the A20 gene, which encodes a zinc finger protein that inhibits NF-kB activity and TNF-induced apoptosis. The study found that C57 and FVB mouse strains have a coding difference in A20 that generates a putative phosphorylation site in C57 mice. Experiments showed the C57 version of A20 is less effective at shutting down NF-kB activity and C57 cells are less susceptible to TNF-induced apoptosis. This suggests the A20 variation could contribute to differences in atherosclerosis susceptibility between C57 and FVB strains by affecting inflammation and apoptosis.
103100
This progress report discusses ongoing near-infrared (NIR) spectroscopy studies. It notes that a new probe design is being developed to improve signal detection in the NIR range. Characterization of a new light source and additional tissue phantom studies are needed. The report identifies ongoing difficulties with depth penetration studies and experimental setup issues. Priorities include analyzing existing data to inform probe redesign, characterizing the new light source, conducting depth penetration and tissue phantom studies, and addressing experimental setup challenges.
More from SHAPE Society (20)
Recently uploaded
Satta Matka Dpboss Kalyan Matka Results Kalyan Chart
SATTA MATKA DPBOSS KALYAN MATKA RESULTS KALYAN CHART KALYAN MATKA MATKA RESULT KALYAN MATKA TIPS SATTA MATKA MATKA COM MATKA PANA JODI TODAY BATTA SATKA MATKA PATTI JODI NUMBER MATKA RESULTS MATKA CHART MATKA JODI SATTA COM INDIA SATTA MATKA MATKA TIPS MATKA WAPKA ALL MATKA RESULT LIVE ONLINE MATKA RESULT KALYAN MATKA RESULT DPBOSS MATKA 143 MAIN MATKA KALYAN MATKA RESULTS KALYAN CHART
Satta Matka Dpboss Kalyan Matka Results Kalyan Chart
SATTA MATKA DPBOSS KALYAN MATKA RESULTS KALYAN CHART KALYAN MATKA MATKA RESULT KALYAN MATKA TIPS SATTA MATKA MATKA COM MATKA PANA JODI TODAY BATTA SATKA MATKA PATTI JODI NUMBER MATKA RESULTS MATKA CHART MATKA JODI SATTA COM INDIA SATTA MATKA MATKA TIPS MATKA WAPKA ALL MATKA RESULT LIVE ONLINE MATKA RESULT KALYAN MATKA RESULT DPBOSS MATKA 143 MAIN MATKA KALYAN MATKA RESULTS KALYAN CHART
IMG_20240615_091110.pdf dpboss guessing
Satta matka fixx jodi panna all market dpboss matka guessing fixx panna jodi kalyan and all market game liss cover now 420 matka office mumbai maharashtra india fixx jodi panna
Call me 9040963354
WhatsApp 9040963354
Sustainable Logistics for Cost Reduction_ IPLTech Electric's Eco-Friendly Tra...
Sustainable Logistics for Cost Reduction_ IPLTech Electric's Eco-Friendly Transport Solution
Satta Matka Dpboss Kalyan Matka Results Kalyan Chart
SATTA MATKA DPBOSS KALYAN MATKA RESULTS KALYAN CHART KALYAN MATKA MATKA RESULT KALYAN MATKA TIPS SATTA MATKA MATKA COM MATKA PANA JODI TODAY BATTA SATKA MATKA PATTI JODI NUMBER MATKA RESULTS MATKA CHART MATKA JODI SATTA COM INDIA SATTA MATKA MATKA TIPS MATKA WAPKA ALL MATKA RESULT LIVE ONLINE MATKA RESULT KALYAN MATKA RESULT DPBOSS MATKA 143 MAIN MATKA KALYAN MATKA RESULTS KALYAN CHART INDIA MATKA KALYAN SATTA MATKA 420 INDIAN MATKA SATTA KING MATKA FIX JODI FIX FIX FIX SATTA NAMBAR MATKA INDIA SATTA BATTA
DPBOSS NET SPBOSS SATTA MATKA RESULT KALYAN MATKA GUESSING FREE KALYAN FIX JO...
DPBOSS NET SPBOSS SATTA MATKA RESULT KALYAN MATKA GUESSING FREE KALYAN FIX JODI ANK LEAK FIX GAME BY DP BOSS MATKA SATTA NUMBER TODAY LUCKY NUMBER FREE TIPS ...
欧洲杯投注-欧洲杯投注外围盘口-欧洲杯投注盘口app|【网址🎉ac22.net🎉】
【网址🎉ac22.net🎉】欧洲杯投注是体育博彩和在线赌场之一，得益于UKGC的三项许可。 成立之初是三名博彩公司将40家博彩商店的合并的结果，共同创建一家名为欧洲杯投注的公司。 欧洲杯投注在线赌场为游戏爱好者提供了300多种游戏，其中200多种老虎机，其他游戏包括二十一点，轮盘，真人荷官和真人赌场等。
Pro Tips for Effortless Contract Management
Tired of chasing down expiring contracts and drowning in paperwork? Mastering contract management can significantly enhance your business efficiency and productivity. This guide unveils expert secrets to streamline your contract management process. Learn how to save time, minimize risk, and achieve effortless contract management.
Kalyan chart 6366249026 India satta Matta Matka 143 jodi fix
Kalyan chart 6366249026 India satta Matta Matka 143 jodi fixsatta Matta matka 143 Kalyan chart jodi 6366249026
63662490260Kalyan chart, satta matta matka 143, satta matka jodi fix , matka boss OTC 420, Indian Satta, India matka, matka ank, spbossmatka, online satta matka game play, live satta matka results, fix fix fix satta namber, free satta matka games, Kalyan matka jodi chart, Kalyan weekly final anl matka 420Unlocking WhatsApp Marketing with HubSpot: Integrating Messaging into Your Ma...
50 million companies worldwide leverage WhatsApp as a key marketing channel. You may have considered adding it to your marketing mix, or probably already driving impressive conversions with WhatsApp.
But wait. What happens when you fully integrate your WhatsApp campaigns with HubSpot?
That's exactly what we explored in this session.
We take a look at everything that you need to know in order to deploy effective WhatsApp marketing strategies, and integrate it with your buyer journey in HubSpot. From technical requirements to innovative campaign strategies, to advanced campaign reporting - we discuss all that and more, to leverage WhatsApp for maximum impact. Check out more details about the event here https://events.hubspot.com/events/details/hubspot-new-delhi-presents-unlocking-whatsapp-marketing-with-hubspot-integrating-messaging-into-your-marketing-strategy/
Discover the Beauty and Functionality of The Expert Remodeling Service
Unlock your kitchen's true potential with expert remodeling services from O'Brien Group Inc. Transform your space into a functional, modern, and luxurious haven with their experienced professionals. From layout reconfiguration to high-end upgrades, they deliver stunning results tailored to your style and needs. Visit obriengroupinc.com to elevate your kitchen's beauty and functionality today.
Ellen Burstyn: From Detroit Dreamer to Hollywood Legend | CIO Women Magazine
In this article, we will dive into the extraordinary life of Ellen Burstyn, where the curtains rise on a story that's far more attractive than any script.
The Most Inspiring Entrepreneurs to Follow in 2024.pdf
In a world where the potential of youth innovation remains vastly untouched, there emerges a guiding light in the form of Norm Goldstein, the Founder and CEO of EduNetwork Partners. His dedication to this cause has earned him recognition as a Congressional Leadership Award recipient.
Efficient PHP Development Solutions for Dynamic Web Applications
Unlock the full potential of your web projects with our expert PHP development solutions. From robust backend systems to dynamic front-end interfaces, we deliver scalable, secure, and high-performance applications tailored to your needs. Trust our skilled team to transform your ideas into reality with custom PHP programming, ensuring seamless functionality and a superior user experience.
一比一原版(QMUE毕业证书)英国爱丁堡玛格丽特女王大学毕业证文凭如何办理
永久可查学历认证【微信：A575476】【(QMUE毕业证书)英国爱丁堡玛格丽特女王大学毕业证成绩单Offer】【微信：A575476】（留信学历认证永久存档查询）采用学校原版纸张、特殊工艺完全按照原版一比一制作（包括：隐形水印，阴影底纹，钢印LOGO烫金烫银，LOGO烫金烫银复合重叠，文字图案浮雕，激光镭射，紫外荧光，温感，复印防伪）行业标杆！精益求精，诚心合作，真诚制作！多年品质 ,按需精细制作，24小时接单,全套进口原装设备，十五年致力于帮助留学生解决难题，业务范围有加拿大、英国、澳洲、韩国、美国、新加坡，新西兰等学历材料，包您满意。
【业务选择办理准则】
一、工作未确定，回国需先给父母、亲戚朋友看下文凭的情况，办理一份就读学校的毕业证【微信：A575476】文凭即可
二、回国进私企、外企、自己做生意的情况，这些单位是不查询毕业证真伪的，而且国内没有渠道去查询国外文凭的真假，也不需要提供真实教育部认证。鉴于此，办理一份毕业证【微信：A575476】即可
三、进国企，银行，事业单位，考公务员等等，这些单位是必需要提供真实教育部认证的，办理教育部认证所需资料众多且烦琐，所有材料您都必须提供原件，我们凭借丰富的经验，快捷的绿色通道帮您快速整合材料，让您少走弯路。
留信网认证的作用:
1:该专业认证可证明留学生真实身份
2:同时对留学生所学专业登记给予评定
3:国家专业人才认证中心颁发入库证书
4:这个认证书并且可以归档倒地方
5:凡事获得留信网入网的信息将会逐步更新到个人身份内，将在公安局网内查询个人身份证信息后，同步读取人才网入库信息
6:个人职称评审加20分
7:个人信誉贷款加10分
8:在国家人才网主办的国家网络招聘大会中纳入资料，供国家高端企业选择人才
→ 【关于价格问题（保证一手价格）
我们所定的价格是非常合理的，而且我们现在做得单子大多数都是代理和回头客户介绍的所以一般现在有新的单子 我给客户的都是第一手的代理价格，因为我想坦诚对待大家 不想跟大家在价格方面浪费时间
对于老客户或者被老客户介绍过来的朋友，我们都会适当给一些优惠。
选择实体注册公司办理，更放心，更安全！我们的承诺：可来公司面谈，可签订合同，会陪同客户一起到教育部认证窗口递交认证材料，客户在教育部官方认证查询网站查询到认证通过结果后付款，不成功不收费！
AI Transformation Playbook: Thinking AI-First for Your Business
I dive into how businesses can stay competitive by integrating AI into their core processes. From identifying the right approach to building collaborative teams and recognizing common pitfalls, this guide has got you covered. AI transformation is a journey, and this playbook is here to help you navigate it successfully.
PM Surya Ghar Muft Bijli Yojana: Online Application, Eligibility, Subsidies &...
PM Surya Ghar Muft Bijli Yojana: Online Application, Eligibility, Subsidies &...Ksquare Energy Pvt. Ltd.
During the budget session of 2024-25, the finance minister, Nirmala Sitharaman, introduced the “solar Rooftop scheme,” also known as “PM Surya Ghar Muft Bijli Yojana.” It is a subsidy offered to those who wish to put up solar panels in their homes using domestic power systems. Additionally, adopting photovoltaic technology at home allows you to lower your monthly electricity expenses. Today in this blog we will talk all about what is the PM Surya Ghar Muft Bijli Yojana. How does it work? Who is eligible for this yojana and all the other things related to this scheme?Recently uploaded (20)
Satta Matka Dpboss Kalyan Matka Results Kalyan Chart
Satta Matka Dpboss Kalyan Matka Results Kalyan Chart
Registered-Establishment-List-in-Uttarakhand-pdf.pdf
Registered-Establishment-List-in-Uttarakhand-pdf.pdf
Satta Matka Dpboss Kalyan Matka Results Kalyan Chart
Satta Matka Dpboss Kalyan Matka Results Kalyan Chart
Sustainable Logistics for Cost Reduction_ IPLTech Electric's Eco-Friendly Tra...
Sustainable Logistics for Cost Reduction_ IPLTech Electric's Eco-Friendly Tra...
Satta Matka Dpboss Kalyan Matka Results Kalyan Chart
Satta Matka Dpboss Kalyan Matka Results Kalyan Chart
DPBOSS NET SPBOSS SATTA MATKA RESULT KALYAN MATKA GUESSING FREE KALYAN FIX JO...
DPBOSS NET SPBOSS SATTA MATKA RESULT KALYAN MATKA GUESSING FREE KALYAN FIX JO...
Kalyan chart 6366249026 India satta Matta Matka 143 jodi fix
Kalyan chart 6366249026 India satta Matta Matka 143 jodi fix
Unlocking WhatsApp Marketing with HubSpot: Integrating Messaging into Your Ma...
Unlocking WhatsApp Marketing with HubSpot: Integrating Messaging into Your Ma...
Discover the Beauty and Functionality of The Expert Remodeling Service
Discover the Beauty and Functionality of The Expert Remodeling Service
Ellen Burstyn: From Detroit Dreamer to Hollywood Legend | CIO Women Magazine
Ellen Burstyn: From Detroit Dreamer to Hollywood Legend | CIO Women Magazine
The Most Inspiring Entrepreneurs to Follow in 2024.pdf
The Most Inspiring Entrepreneurs to Follow in 2024.pdf
Efficient PHP Development Solutions for Dynamic Web Applications
Efficient PHP Development Solutions for Dynamic Web Applications
AI Transformation Playbook: Thinking AI-First for Your Business
AI Transformation Playbook: Thinking AI-First for Your Business
PM Surya Ghar Muft Bijli Yojana: Online Application, Eligibility, Subsidies &...
PM Surya Ghar Muft Bijli Yojana: Online Application, Eligibility, Subsidies &...
Coronary artery disease among asymptomatic diabetic and non-diabetic patients undergoing coronary CT angiography
- 1. CORONARY ARTERY DISEASE AMONG ASYMPTOMATIC DIABETIC AND NONDIABETIC PATIENTS UNDERGOING CORONARY CT ANGIOGRAPHY Zeina AR, Blinder J, Rosenschein U, Zaid G , Barmeir E _______________________________________________________________________________ Zeina et al, Coronary Artery Disease 2008, 19:37–41
- 4. The aim of this study was to determine the prevalence and severity of CAD and the plaque composition in asymptomatic diabetic patients undergoing coronary CT angiography (CCTA) _______________________________________________________________________________ Purpose Zeina et al, Coronary Artery Disease 2008, 19:37–41
- 6. Table 1. Baseline characteristics of diabetic and non-diabetic patients. _______________________________________________________________________________ Zeina et al, Coronary Artery Disease 2008, 19:37–41 0.96 101 (35) 15 (36) Smoking, n (%) 0.34 152 (53) 19 (45) Hyperlipidemia, n (%) 0.17 138 (48) 25 (59) Hypertension, n (%) 0.19 126 (44) 14 (33) Family history, n (%) 0.17 213 (74) 38 (90) Male gender, n (%) 0.10 56 ± 9 58 ± 8 Age (years ± SD) (N= 286) (N= 42) P value Non-diabetic patients Diabetic patients
- 9. Table 2. CCTA characteristics of the study population and comparison between diabetic and non-diabetic patients. * P value < 0.05 is considered significant. CCTA= coronary CT angiography _______________________________________________________________________________ Results Zeina et al, Coronary Artery Disease 2008, 19:37–41 0.1 1 (0.3%) 1 (2%) Three-vessel disease 0.3 2 (0.7%) 1 (2%) Two-vessel disease < 0.0001 16 (5.6%) 10 (24%) One-vessel disease < 0.0001 2.8 5.5 Segments with plaques/patient 0.07 141 (49%) 27 (64%) Non-obstructive CAD < 0.0001 19 (6.6%) 12 (29%) Obstructive CAD 0.006 211 (74%) 39 (93%) Coronary plaques < 0.0001 79.9 ± 16 370 ± 96 Total Agatston score (n= 286) (n= 42) P value * Non-diabetic patients Diabetic patients
- 10. 54-year-old asymptomatic diabetic patient MIP 3D-VR CCTA Zeina et al, Coronary Artery Disease 2008, 19:37–41