This document discusses research into identifying immune responses against oxidized LDL in humans and developing an immunization therapy to inhibit atherosclerosis. The research found that immunization of apoE null mice with specific MDA-modified apoB-100 peptide sequences activated athero-protective immune responses and significantly reduced atherosclerotic plaque development compared to controls. This suggests vaccination with these peptide sequences may be a potential therapy for atherosclerosis by stimulating protective immune responses against oxidized LDL.