This document summarizes research on the effectiveness and cost-effectiveness of influenza vaccination, statin drugs, and aspirin for preventing cardiovascular events. It finds that influenza vaccination has been shown to reduce hospitalizations for cardiovascular disease by 6-12% and lower mortality by 48-50% based on observational studies. The cost per life saved from influenza vaccination is estimated to be $13,200, much lower than the $198,000 per life saved by statin drugs. While statins and aspirin are effective therapies, influenza vaccination provides benefits to cardiovascular health at the population level due to its low cost and ability to prevent thousands of events each year. More research is still needed to understand the mechanisms by which influenza increases cardiovascular risk