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CONCEPT OF DISEASE
Dr.Suresh Babu
Professor
Dept of Public Health Dentistry
Navodaya Dental College
A condition in which body health is impaired
A condition of the body or some part or
organ of the body in which its functions
are disrupted or deranged”
A maladjustment of the human organism to
the environment
Disease is considered a social phenomenon,
occurring in all societies
The term “disease” literally means “without ease”
Illness is a subjective state of the person who feels
aware of not being well
Sickness is a state of social dysfunction, i.e., a role
that the individual assumes when ill (“sickness
role”)
CONCEPTS OF CAUSATION
• The supernatural theory of disease, the
theory of humors, the concept of
contagion, miasmatic theory of disease,
the theory of spontaneous generation
Germ theory of disease
Disease agent  Man  Disease
The germ theory of disease, though it was a
revolutionary concept, led many
epidemiologists to take one-sided view of
disease causation
Epidemiological triad
Environment
Agent Host
Multifactorial causation
• Pettenkofer of Munich (1819-1901) was an
early proponent of this concept
• Epidemiology has contributed significantly
to our present day understanding of
multifactorial causation of disease
Web of causation
• This model of disease causation was
suggested by MacMahon and Pugh in
their book: "Epidemiologic Principles and
Methods
NATURAL HISTORY OF DISEASE
•
Epidemiological triad
Agent factors:
1.Biological agents
2. Nutrient agents
3. Physical agents
4. Chemical agents
5. Mechanical agents
6. Social agents
Host factors (intrinsic)
I) Demographic
(ii) Biological characteristics
(iii) Social and economic characteristics
(iv) Lifestyle factors
Environmental factors (extrinsic)
• physical,
• biological and
• psychosocial
Risk factors
• an attribute or exposure that is significantly
associated with the development of a disease
• a determinant that can be modified by
intervention, thereby reducing the possibility
of occurrence of disease or other specified
outcomes
• Risk factors are often suggestive, but absolute
proof of cause and effect between a risk factor
and disease is usually lacking
• The important thing about risk factors is that they
are observable or identifiable prior to the event
they predict
• Risk factors may be truly causative
• They may be predictive only in a statistical
sense
• Some risk factors can be modified; others
cannot be modified.
Disease Risk factors
• Heart disease Smoking, high blood pressure, elevated
serum cholesterol, diabetes, obesity, lack of exercise,
• Cancer Smoking, alcohol, solar radiation, ionizing
radiation, work-site hazards, environmental pollution,
medications, infectious agents, dietary factors.
• Stroke High blood pressure, elevated cholesterol,
smoking
• Motor vehicle accidents Alcohol, non-use of seat
belts, speed, automobile design, roadway design
• Diabetes Obesity, diet
• Cirrhosis of liver Alcohol
Spectrum of disease
• The term "spectrum of disease" is a graphic
representation of variations in the manifestations
of disease
• At one end of the disease spectrum are
subclinical infections which are not ordinarily
identified and at the other end are fatal illnesses.
• In the middle of the spectrum lie illnesses
ranging in severity from mild to severe
Iceberg of disease
CONCEPT.ppt

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CONCEPT.ppt

  • 1. CONCEPT OF DISEASE Dr.Suresh Babu Professor Dept of Public Health Dentistry Navodaya Dental College
  • 2. A condition in which body health is impaired A condition of the body or some part or organ of the body in which its functions are disrupted or deranged” A maladjustment of the human organism to the environment
  • 3. Disease is considered a social phenomenon, occurring in all societies The term “disease” literally means “without ease” Illness is a subjective state of the person who feels aware of not being well Sickness is a state of social dysfunction, i.e., a role that the individual assumes when ill (“sickness role”)
  • 4. CONCEPTS OF CAUSATION • The supernatural theory of disease, the theory of humors, the concept of contagion, miasmatic theory of disease, the theory of spontaneous generation
  • 5. Germ theory of disease Disease agent  Man  Disease The germ theory of disease, though it was a revolutionary concept, led many epidemiologists to take one-sided view of disease causation
  • 7. Multifactorial causation • Pettenkofer of Munich (1819-1901) was an early proponent of this concept • Epidemiology has contributed significantly to our present day understanding of multifactorial causation of disease
  • 8. Web of causation • This model of disease causation was suggested by MacMahon and Pugh in their book: "Epidemiologic Principles and Methods
  • 9.
  • 10. NATURAL HISTORY OF DISEASE •
  • 12. Agent factors: 1.Biological agents 2. Nutrient agents 3. Physical agents 4. Chemical agents 5. Mechanical agents 6. Social agents
  • 13. Host factors (intrinsic) I) Demographic (ii) Biological characteristics (iii) Social and economic characteristics (iv) Lifestyle factors
  • 14. Environmental factors (extrinsic) • physical, • biological and • psychosocial
  • 15. Risk factors • an attribute or exposure that is significantly associated with the development of a disease • a determinant that can be modified by intervention, thereby reducing the possibility of occurrence of disease or other specified outcomes
  • 16. • Risk factors are often suggestive, but absolute proof of cause and effect between a risk factor and disease is usually lacking • The important thing about risk factors is that they are observable or identifiable prior to the event they predict
  • 17. • Risk factors may be truly causative • They may be predictive only in a statistical sense • Some risk factors can be modified; others cannot be modified.
  • 18. Disease Risk factors • Heart disease Smoking, high blood pressure, elevated serum cholesterol, diabetes, obesity, lack of exercise, • Cancer Smoking, alcohol, solar radiation, ionizing radiation, work-site hazards, environmental pollution, medications, infectious agents, dietary factors. • Stroke High blood pressure, elevated cholesterol, smoking • Motor vehicle accidents Alcohol, non-use of seat belts, speed, automobile design, roadway design • Diabetes Obesity, diet • Cirrhosis of liver Alcohol
  • 19. Spectrum of disease • The term "spectrum of disease" is a graphic representation of variations in the manifestations of disease • At one end of the disease spectrum are subclinical infections which are not ordinarily identified and at the other end are fatal illnesses. • In the middle of the spectrum lie illnesses ranging in severity from mild to severe