This document discusses animal cloning. It defines animal cloning as the artificial creation of a genetically identical animal with the same DNA. Therapeutic cloning is used for medical research by cloning cells from adults, while reproductive cloning creates cloned animals. The cloning process involves extracting DNA from a donor cell and placing it into an egg cell whose nucleus was removed. Dolly the sheep was the first mammal cloned from an adult cell. The document lists many animals that have been successfully cloned.

1. Cloning within
Animals
Nikki Sumner
Biology 101
Fall 2011

2. What exactly is Animal
Cloning?
• When the term animal cloning
is used, it is typically referring
to the artificial creation of an
identical genetic animal; this
means that both animals will
have the exact same DNA
• Cloning does not refer to
multiple births or normal
reproduction, including that
of tissues or organs

3. Therapeutic Cloning
vs.
Reproductive Cloning
• Therapeutic Cloning refers to cloning cells
from an adult animal or human to use for
medical reasons, such as research
• Reproductive Cloning refers to making cloned
animals

4. How does cloning work?
•Two females are needed to
begin the cloning process
•A body cell is extracted from
the first female, this is where
the DNA is extracted from
•An egg cell is then extracted
from the second female, the
nucleus is extracted from the
egg cell
•Once the nucleus is
extracted from the 2nd
female’s egg cell, the 1st
female’s DNA is placed in the
2nd females empty egg cell

5. • Once they are
combined, the egg cell is
placed into the 1st
female’s uterus
• The cloned embryo
will now begin to
develop
• This is the stage where
the egg cell could fail
and not develop into
the embryo as planned

6. What are the concerns with
animal cloning?
• High failure rate
• DNA Mutations
• Developmental
Problems
• Ethical Issues

7. How can cloning be used?
• Repopulate endangered species
• Help aid in animal breeding for those species
that have difficulty
• Bring back extinct species
• Possible treatment of disorders

8. What animals have been
successfully cloned?
• Carp was the first fish ever cloned in China in 1963
• A mouse, named Masha, was the first cloned mammal in 1986, was cloned in
Russia
• A horse, named Prometea, was cloned in Italy, in 2003
• 5 twin piglets were cloned in London in 2000
• A cat, named CC, was the first cloned cat and pet in Texas in 2001
• Snuppy the dog was first cloned in Korea in 2005
• Little Nicky, a cat, was the first cloned animal for use in a commercial in California
in 2004
• Ombretta, the Mouflan, was the first endangered species to be cloned in Italy, in
2000
• Andi, the monkey, was cloned in Oregon in 2000
• Idaho Gem the Mule was the first animal hybrid to be cloned in 2003
• Pyrenean Ibex is the first extinct animal to be cloned in 2009
• Dolly, the sheep, was the first mammal to be cloned from an adult donor in
Scotland in 1996

9. Dolly the Sheep
and
Jeremy Rifkin

10. Works Cited
• "16 Most Notable Cloned Animal | Scienceray." Scienceray | All That Is Science, Astronomy,
Biology, Chemistry, Mathematics, Physics. Web. 08 Nov. 2011.
<http://scienceray.com/technology/applied-science/16-most-notable-cloned-
animal/>.
• Biotechnology: Friend or Foe?. Films Media Group, 2000. Films On Demand. Web. 7 November
2011. <http://digital.films.com/PortalPlaylists.aspx?aid=11561&xtid=11530>.
• Bren, Linda. "Cloning: Revolution Or Evolution in Animal Production?" FDA consumer 2003: 28-
33. ProQuest Research Library. Web. 7 Nov. 2011
<http://ezproxy.hacc.edu/login?url=http://search.proquest.com/docview/227040801?
accountid=11302>.
• "Cloning Fact Sheet." Oak Ridge National Laboratory. Web. 08 Nov. 2011.
<http://www.ornl.gov/sci/techresources/Human_Genome/elsi/cloning.shtml#anim
als>.
• Erijman, Ariel, Dantes, Ada, Bernheim, Reut, Shifman, Julia M., Peleg, Yoav, Transfer-PCR (TPCR):
A highway for DNA cloning and protein engineering, Journal of Structural Biology, Volume
175, Issue 2, August 2011, Pages 171-177, ISSN 1047-8477, 10.1016/j.jsb.2011.04.005.
(http://www.sciencedirect.com/science/article/pii/S1047847711001109

11. Works Cited Continued
• Jurveston, Steve. Cute Clones. 2009. Photograph. Flickr. Flickr. Yahoo, 3 Mar. 2009. Web. 31 Oct.
2011. <http://www.flickr.com/photos/jurvetson/3327872958/>.
• Romanov, Michael. "Gene Cloning and DNA Analysis: An Introduction, 5th Ed." The Journal
of heredity 98.1 (2007): 97-8. ProQuest Research Library. Web. 7 Nov. 2011.
• Skuds. Scars. 2006. Photograph. Flickr. Flickr. Yahoo, 27 June 2006. Web. 05 Nov. 2011.
<http://www.flickr.com/photos/skuds/176452661/>.
• Wheeler, Richard. Benzopyrene DNA Adduct 1JDG.png. 2007. Photograph. Wikipedia. Wikipedia.
2007. Web. 11 Nov.2011.
<http://en.wikipedia.org/wiki/File:Benzopyrene_DNA_adduct_1JDG.png>.
• Wirth, Carl. Gencode. 2010. Photograph. Flickr. Flickr. Yahoo, 29 July 2010. Web. 11 Nov. 2011.
<http://www.flickr.com/photos/naturalismus/4839348174/>.
• Ynse. DNA Rendering. 2007. Photograph. Flickr. Flickr. Yahoo, 12 June 2007. Web. 01 Nov. 2011.
<http://www.flickr.com/photos/ynse/542370154/>.