2. TABLE OF CONTENT
• WHAT ARE ANTIBIOTICS?
• CLASSIFICATION OF ANTIBIOTICS?
According to spectrum of antibiotics
According to the mode of action antibiotics
3. What are Antibiotics…?
An antibiotic is a drug that kills or inhibits the
growth of microorganisms.
Antibiotics belong to a class of antimicrobials, in
which the sub-classes includes anti-viral, anti-fungal,
and anti-parasitic drugs.
The first antibiotic was discovered by Alexander
Fleming in 1928.
5. 1. On the basis of spectrum of antibiotic:
Broad spectrum antibiotics:
The Broad spectrum antibiotics affect several
types of bacteria and fungi.
Narrow spectrum antibiotics:
These are used only when we know the specific
type of the microorganism.
6. 2. One the basis of mode of action of antibiotic:
Bactericidal antibodies:
They kill bacteria by inhibiting cell wall synthesis.
Example include:
Beta-lactam antibiotics----
o Penicillin(amoxicillin) [ commonly used for infection
o Cephalosporin(Keflex) [commonly used for surgical prophylaxis.]
o Metronidazole [commonly used as bacterial infections like
skin and GI Tract infection]
Bacteriostatic antibiotics:
They limit the growth of bacteria by interfering with bacterial protein production, DNA
replication.
Example:
o Tetracycline [used as respiratory tract, urinary tract, etc.]
o Sulfonamide [used as diabetes and pain relief ]
o Macrolides [used as Dental Abscess , Lymph Disease, etc. ]
(erythromycin)