PRESENTATION based on the totally topic of ADRENERGIC DRUGS here you find all over the information about this topic as i clear out all this for my viewers.
2. TABLE OF CONTENTS:
Adrenergic Drugs?
What are Adrenergic Agonists? Sympathomimetic/ Adrenomimetics?
Types of stimulants?
What are adrenergic Antagonists/blockers?
Types of blockers?
Alpha-blockers Vs. Beta-blockers
References
3. Adrenergic Drugs:
Adrenergic drugs are medications that stimulate certain nerves in the body.
by mimicking the action of the chemical messengers epinephrine and
norepinephrine
by stimulating their releases
Uses:
Uses in life threating conditions including : EXAMPLE: albuterol
` Salmeterol etc.
Cardiac arrest
Shock
Asthma attack
Allergic reaction
4. Adrenergic Agonists:
(Adrenomimetics)
An adrenergic agonist is a drug that stimulates a response from the adrenergic receptors.
Main Categories of Adrenergic receptors are:
Alpha (α1, α2 )→Anaphylactic shock, hypotension, nasal congestion and hemorrhage
Beta (β1, β2, and β3 ) → asthma, congestive heart failure.
Dopamine (D1-D5) → shock, congestive heart failure and Parkinson’s disease.
Drugs:
Isoproterenolum (β- adrenomimetic)
Fenoterolum (β2- adrenomimetic)
Dobutaminum (β1- adrenomimetic)
Terbutalinum
Galazolin(α-adrenomimetic)
5. Sympathomimetic Drugs:
Sympathomimetic drugs are stimulant compounds which mimic the
effects of agonists of the sympathetic nervous system.
Drugs: Catecholamine including:
I. Phenylephrine
II. Norepinephrine (noradrenaline)
III. Dopamine and epinephrine etc.
Uses of Drug(to treat):
Cardiac arrest
Hypotensive state
Allergic reaction
Asthma etc.
6. Adrenergic antagonists
Adrenergic antagonists bind to the adrenoreceptors but do not trigger
the usual receptor-mediated intracellular effects.
Types :
• Alpha-blockers
• Beta-blockers
7. ALPHA-BLOCKERS Vs. BETA-
BLOCKERS
They relax certain muscles and help
small blood vessels remain open.
They work by keeping hormone
norepinephrine from tightening the
muscles in the walls of vessels which
causes them to remain relaxed. This
improves blood flow and lowers BP.
i.e;
Doxazosin and Prazoxin:
• Used to treat high BP
• Also used in men to treat enlarged
prostrate
Side effects:
• Might decrease low density
lipoprotein cholesterol (LDL)
They are also called blocking
agents, treat a variety of conditions
such as high BP and migraines.
Work by blocking the effects of
epinephrine. i.e;
Atenolol and Nadolol:
• Used to treat high blood pressure
• Migraines
• Can orally be taken and injections
also available
Side-effects:
• As same as a-blockers