This document provides an overview of different types of epidemiological studies. It discusses observational studies like descriptive and analytical studies, which include case-control and cohort studies. Experimental studies like randomized controlled trials, field trials, and community trials are also covered. Specific details are given on case-control and cohort study designs. The document also discusses cross-sectional, longitudinal, and community trial study types. Key epidemiological concepts like the epidemiological triad and reservoirs are briefly explained. Sample epidemiology questions and their answers are provided at the end.
Social and Preventive Medicine Classroom discussion topic on types of Epidemiological study designs available.
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Social and Preventive Medicine Classroom discussion topic on types of Epidemiological study designs available.
sole reference is Park text book 20th edition
This is an easiest power-point slide you will get on topic Epidemiology. It’s basic of Epidemiology. This ppt includes difference between observational study & experimental study. Classification of Epidemiological study. You can read this & have an overview of Epidemiological study design in short. This power point will help you regarding understanding Epidemiological study. Including cohort study, case control study, descriptive study. This includes advantage & disadvantage of many studies of Epidemiological study design such ase cohort study, case control study, analytical study. It was our group presentation so we made with all our affords. I was the leader of our team I can assure you, you won’t get disappointment after studying this slides.
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1. WELCOME TO RADIX ACADEMY
SUBJECT: EPIDEMIOLOGY
TOPIC: DETAILS ON
EPIDEMIOLOGICAL STUDIES
PRESENTEDBY-
JAHANGIR ALAM
RN. BSN.MPH MSN(IN COURSE)
2. Types of Epidemiological Studies
There are two broad types of epidemiological studies:
1. Observational studies – we do not interfere in the process of the disease,
but simply observe the disease and the associated factors.
2. Experimental studies – deliberate intervention is made and the effect of
such intervention is observed.
3. Types of Epidemiological Studies
Observational studies include:
A. Descriptive observational study and
B. Analytical observational study
Analytical observational studies further classified as-
i) Case control and
ii) Cohort studies
4. Experimental studies
There are three main types of experimental studies.
1. Randomized controlled trials (RCT) – uses patients as units of study, mostly for
assessing a new therapy.
2. Field trials – uses healthy individuals as units of study, mostly for assessing
preventive agents like vaccines.
3. Community trials – uses communities as units of study for assessing community
based interventions like health status in villages with a training program versus in
those without.
5. Observational and Case Control Study
Observational study
The disease distribution in a community is described in terms of
Time, Place and Person.
This study can give clues about the ‘risk factors’ and the cause.
6. Case – control study
This is a retrospective study.
I. A group of ‘cases’ of a disease is assembled.
II. Another group of matched ‘controls’ (free from disease) is assembled.
III. The history of exposure to the suspected risk factor is ascertained in all
the members of both the groups
IV. The prevalence of the exposure among the cases is compared with that in
the controls.
7. Case – control study cont.….
V. Factors which are significantly more in the cases group as
compared to the control are reaffirmed as the risk factors.
-By same argument, factors which are significantly higher in the
controls are noted as the possible protective factors.
VI. Odd’s ratio (OR) is calculated in case – control studies to
estimate the risk associated with each risk factor
8. Cohort study:
A cohort study is a particular form of longitudinal study that samples a cohort (a group of
people who share a defining characteristic, typically those who experienced a common event in
a selected period, such as birth or graduation), performing a cross-section at intervals through
time. It is a type of panel study where the individuals in the panel share a common
characteristic.
Examples of cohort studies are (1) Framingham Cohort study, (2) Swiss HIV Cohort study,
and (3) The Danish Cohort study of psoriasis and depression. These studies may be prospective,
retrospective, or a combination of both of these types.
9. Sample question
Which type of study is cheaper and faster?
A. Retrospective study.
B. Prospective study.
10. Cross sectional study cont.…
A cross-sectional study is a type of research design in which
investigator collect data from many different individuals at a single
point in time.
11. Longitudinal study
In a longitudinal study, researchers repeatedly examine the same individuals to
detect any changes that might occur over a period of time.
Longitudinal studies are a type of correlational research in which researchers
observe and collect data on a number of variables without trying to influence those
variables.
One of the longest longitudinal studies, the Harvard Study of Adult Development, has
been collecting data on the physical and mental health of a group of Boston men for
over 80 years!
12. Cohort study cont.…
I. One group of people exposed to the suspected RF is identified.
This is the ‘Exposure cohort’
II. Another group of people similar to the exposure cohort, but DEFINITELY NOT
EXPOSED are identified.
– This is the ‘Control or Non-exposed cohort’.
III. The groups are similar except for the ‘exposure’ to the risk factor.
• It is made sure that none of the members in both the groups have the disease under
investigation
IV. Both the cohorts are regularly followed up for a definite period and examined for
development of the disease at regular intervals
13. Cohort study cont.….
V. If the incidence of the disease is significantly higher in the exposed cohort, the
association is confirmed
VI. Relative Risk (RR) is calculated in cohort studies to estimate the risk
associated with each risk factor
Formula of Relative Risk:
14.
15. Field Study
• Mainly for vaccines or preventive agents
• Hence units of study are HEALTHY individuals or those without disease
• The incidence among vaccinated is compared with the incidence among
non vaccinated
• The two groups i.e. vaccinated and non vaccinated can not usually be
decided by randomization
• Hence they may not be exactly comparable
16. Community Trial
• Some communities e.g. districts may have the public health intervention
like a new method of water purification
• Other districts continue with the older methods
• The incidence of water-borne disease can be compared among these
districts
The usual sequence of progress from one type of study to the next, as the
evidence of an association builds up is as follows:
i. Descriptive study of the disease
ii. Case control study using the diagnosed cases and confirmed controls
iii. Cohort study: using ‘exposed’ and ‘un –exposed’ cohorts
17. Epidemiological Triad
The epidemiological triad or epidemiological triangle is a
traditional model to explain how infectious diseases are caused
and transmitted. The model is very simple and represents a high-
concept, bird’s-eye view of infectious diseases.
20. Sample question
1. A key features of a cross-sectional study are-
a. It usually provides information on prevalence rather than incidence
b. It is limited to health exposures and behaviors rather than health outcomes
c. It is more useful for descriptive epidemiology than it is for analytic epidemiology
d. It is synonymous with survey.
2. A cohort study differs from a case-control study in that-
a. Subjects are enrolled or categorized on the basis of their exposure status in a cohort study
but not in a case-control study
b. Subjects are asked about their exposure status in a cohort study but not in a case-control
study
c. Cohort studies require many years to conduct, but case-control studies do not
21. Sample question
3. The hallmark feature of an analytic epidemiologic study is: (Choose one best answer)
a. Use of an appropriate comparison group
b. Laboratory confirmation of the diagnosis
c. Publication in a peer-reviewed journal
d. Statistical analysis using logistic regression
4. A study in which children are randomly assigned to receive either a newly formulated vaccine or the currently
available vaccine, and are followed to monitor for side effects and effectiveness of each vaccine, is an example
of which type of study?
a. Experimental
b. Observational
c. Cohort
d. Case-control
e. Clinical trial
22. Answer to the sample questions
Answer to question no 1: a, c, and d.
Answer to question no 2: a
Answer to question no 3: a
Answer to question no 4: a, e
23. Types of reservoir
Human reservoir
When organism lodges
in human body
Animal reservoir
When organism lodges
in animals other then
human body.
Reservoir in non
living things
When organism exist in
non living things and is
able to spread disease.
24. Stages of disease
A. Stage 1; Incubation period: Time between exposure to a pathogen
and apparent of features.
B. Stage 2; Prodromal period: Increasing the number of infectious agent
and immune system start to reacting with them.
C. Stage 3; Acute period: rapid multiplication of pathogen.
D. Stage 4; Convalescence period: The patient may recover gradually but
may serve as a source of infection.