The Civil War lasted from 1861 to 1865 and was fought between the Northern and Southern states over issues including states' rights and slavery. Some key battles included Fort Sumter in 1861, Antietam in 1862, Gettysburg in 1863, and Lee's surrender to Grant at Appomattox Court House in 1865, marking the end of the war. Over 600,000 soldiers died in the conflict between the Union and Confederate forces.