Established in 1962 Chem Service is the largest independent supplier of Analytical Reference Materials and the original source of small quantities of organic chemicals. Chem Service also has over 2,000 Pesticide Standards, including Pesticide Standards for Cannabis in its catalogue. Chem Service offers Custom made Standards manufactured to your specific requirements, all standards are accredited to ISO 17043:2016; ISO/IEC 17025:2005; ISO 9001:2015 Quality Management System.
Over 95% of Chem Services’ neat Standards Grade materials have a purity of 98.0% or greater.
Chem Services’ worldwide customers are found in the chemical, government, food quality, agricultural and life science research communities.
Scynexis Fully Integrated Drug Discovery & Development 2011 Overviewbrycechaney
SCYNEXIS provides fully integrated drug discovery and development solutions including medicinal chemistry, lead optimization, ADMET-PK testing, and cGMP manufacturing. They have over 140 employees across two campuses with experience from major pharmaceutical companies. SCYNEXIS has delivered 11 pre-clinical drug candidates over the last 5 years and developed a chemical manufacturing process for an NDA.
7th Cold Chain Distribution for PharmaceuticalsAbby Lombardi
This document provides information about the 7th Annual Cold Chain Distribution for Pharmaceuticals conference taking place from September 21-24, 2009 in Philadelphia, Pennsylvania. The conference will focus on partnerships, transportation processes, risk mitigation and temperature-controlled shipment of pharmaceutical products and supplies. Topics will include re-evaluating transportation and logistics strategies, ensuring regulatory compliance, establishing qualified shipping lanes and processes, and implementing effective "last mile" logistics. The conference will feature speakers from various pharmaceutical and logistics companies and government agencies. Pre-conference discussion forums and conference tracks will address issues such as cold chain program management, new refrigeration technologies, biological materials and clinical supplies shipping, and clinical logistics.
Bilcare GCS provides end-to-end clinical trial material supply chain services including packaging, labeling, storage, distribution, and returns/destruction. It has facilities in India and a global depot network to support clinical trials worldwide. Services include primary and secondary packaging, comparator sourcing, IVRS/IWRS, logistics and supply chain management, and QA/QC through qualified professionals and compliant facilities.
7th Cold Chain Management & Temperature Control SummitAbby Lombardi
This document advertises a Cold Chain Management & Temperature Control Summit taking place from February 24-27, 2009 in Toronto, Canada. It provides information on registration, speakers, sessions, workshops, and sponsors. The summit will focus on strengthening end-to-end cold chain practices for temperature-sensitive pharmaceuticals. Pre-conference workshops on February 25th will cover new technologies, temperature maintenance in transportation, and meeting transport service provider obligations.
EFRAC is an ISO 17025 accredited pharmaceutical testing facility located in Chennai, India. It has 11 regulatory accreditations and conducts a wide range of tests for drugs, cosmetics, and related products according to international standards. EFRAC utilizes cutting-edge technology and qualified instrumentation to provide precise, reliable, and legally defensible testing data to clients.
When Coating runs smoothly: Enhance your Coating Process with a new Particle ...Merck Life Sciences
Watch the presentation of this webinar here: https://bit.ly/3bJypPv
Tablet coating simplified. Finding the perfect coating for your formulation can be challenging. A particle engineered polyvinyl alcohol helps you to optimize your process while maintaining full flexibility in designing the right coating formulation at the right time.
In film coating applications water soluble polymers like polyvinyl alcohol (PVA) take a unique position. PVA can be used in immediate release coatings and provides an exceptional moisture and oxygen barrier. A dedicated particle design allows rapid dissolving times and due to the low viscosities of PVA solutions high solid contents can be obtained leading to a high process efficacy.
The webinar will cover coating formulation development as well as novel technologies for characterization of coated tablets that can easily be implemented during production. Optical coherence technology (OCT) and laser scanning microscopy (LSM) can be valuable tools to assess the coating quality.
In this webinar, you will learn:
• How to create your coating formulation by utilizing a broad excipient toolbox
• Potential advantages of PVA as a stable moisture and oxygen barrier to protect challenging drug substances
• Creating the perfect surface finishing
• How to utilize novel analytical technologies to boost your formulation development
This document summarizes innovations in device coatings used in the biomedical industry. It discusses the market size and growth of different polymer coating categories. It also describes common coating materials like polyvinylpyrrolidone and hyaluronic acid and considerations for coating chemistry, manufacturing processes, testing, regulations and costs. Key challenges include improving coating durability, reducing particulate shedding and demonstrating anti-microbial efficacy over long periods of time. Device manufacturers must work closely with coating suppliers to thoroughly test coatings and understand manufacturing and regulatory requirements.
CoreRx is a contract pharmaceutical development and manufacturing organization that helps get you into the clinic faster, providing a complete spectrum of cGMP solutions for pharmaceutical dosage form development. Our wide range of support services, extensive instrumentation and rigorous quality systems provide timely results communicated in a clear, efficient and consistent manner.
Scynexis Fully Integrated Drug Discovery & Development 2011 Overviewbrycechaney
SCYNEXIS provides fully integrated drug discovery and development solutions including medicinal chemistry, lead optimization, ADMET-PK testing, and cGMP manufacturing. They have over 140 employees across two campuses with experience from major pharmaceutical companies. SCYNEXIS has delivered 11 pre-clinical drug candidates over the last 5 years and developed a chemical manufacturing process for an NDA.
7th Cold Chain Distribution for PharmaceuticalsAbby Lombardi
This document provides information about the 7th Annual Cold Chain Distribution for Pharmaceuticals conference taking place from September 21-24, 2009 in Philadelphia, Pennsylvania. The conference will focus on partnerships, transportation processes, risk mitigation and temperature-controlled shipment of pharmaceutical products and supplies. Topics will include re-evaluating transportation and logistics strategies, ensuring regulatory compliance, establishing qualified shipping lanes and processes, and implementing effective "last mile" logistics. The conference will feature speakers from various pharmaceutical and logistics companies and government agencies. Pre-conference discussion forums and conference tracks will address issues such as cold chain program management, new refrigeration technologies, biological materials and clinical supplies shipping, and clinical logistics.
Bilcare GCS provides end-to-end clinical trial material supply chain services including packaging, labeling, storage, distribution, and returns/destruction. It has facilities in India and a global depot network to support clinical trials worldwide. Services include primary and secondary packaging, comparator sourcing, IVRS/IWRS, logistics and supply chain management, and QA/QC through qualified professionals and compliant facilities.
7th Cold Chain Management & Temperature Control SummitAbby Lombardi
This document advertises a Cold Chain Management & Temperature Control Summit taking place from February 24-27, 2009 in Toronto, Canada. It provides information on registration, speakers, sessions, workshops, and sponsors. The summit will focus on strengthening end-to-end cold chain practices for temperature-sensitive pharmaceuticals. Pre-conference workshops on February 25th will cover new technologies, temperature maintenance in transportation, and meeting transport service provider obligations.
EFRAC is an ISO 17025 accredited pharmaceutical testing facility located in Chennai, India. It has 11 regulatory accreditations and conducts a wide range of tests for drugs, cosmetics, and related products according to international standards. EFRAC utilizes cutting-edge technology and qualified instrumentation to provide precise, reliable, and legally defensible testing data to clients.
When Coating runs smoothly: Enhance your Coating Process with a new Particle ...Merck Life Sciences
Watch the presentation of this webinar here: https://bit.ly/3bJypPv
Tablet coating simplified. Finding the perfect coating for your formulation can be challenging. A particle engineered polyvinyl alcohol helps you to optimize your process while maintaining full flexibility in designing the right coating formulation at the right time.
In film coating applications water soluble polymers like polyvinyl alcohol (PVA) take a unique position. PVA can be used in immediate release coatings and provides an exceptional moisture and oxygen barrier. A dedicated particle design allows rapid dissolving times and due to the low viscosities of PVA solutions high solid contents can be obtained leading to a high process efficacy.
The webinar will cover coating formulation development as well as novel technologies for characterization of coated tablets that can easily be implemented during production. Optical coherence technology (OCT) and laser scanning microscopy (LSM) can be valuable tools to assess the coating quality.
In this webinar, you will learn:
• How to create your coating formulation by utilizing a broad excipient toolbox
• Potential advantages of PVA as a stable moisture and oxygen barrier to protect challenging drug substances
• Creating the perfect surface finishing
• How to utilize novel analytical technologies to boost your formulation development
This document summarizes innovations in device coatings used in the biomedical industry. It discusses the market size and growth of different polymer coating categories. It also describes common coating materials like polyvinylpyrrolidone and hyaluronic acid and considerations for coating chemistry, manufacturing processes, testing, regulations and costs. Key challenges include improving coating durability, reducing particulate shedding and demonstrating anti-microbial efficacy over long periods of time. Device manufacturers must work closely with coating suppliers to thoroughly test coatings and understand manufacturing and regulatory requirements.
CoreRx is a contract pharmaceutical development and manufacturing organization that helps get you into the clinic faster, providing a complete spectrum of cGMP solutions for pharmaceutical dosage form development. Our wide range of support services, extensive instrumentation and rigorous quality systems provide timely results communicated in a clear, efficient and consistent manner.
CoreRx is a dosage form development company specializing in preformulation, formulation development, analytical development, clinical manufacturing, and commercial manufacturing. It has experienced professionals and state-of-the-art facilities. CoreRx focuses on client satisfaction through effective communication, flexibility, speed, and high quality systems. It offers a range of services from preformulation to stability studies to meet clients' drug development needs.
Cavalier Pharma Logistics Group Capabilities & IQP Overview winyard2015Stephen D. Winyard
Cavalier Pharma Logistics provides specialized logistics services for the transportation of pharmaceutical products globally. They excel in shipping time and temperature sensitive drugs, clinical trial supplies, and other goods. Through their specialized services and attention to detail, they aim to provide unique customer solutions and ensure product quality while in transit. They seek to be a global service provider of choice through logistics competency, helping customers gain advantages.
Commercializing antibody-drug conjugates: a CMO’s journeyMerck Life Sciences
Watch the webinar here: https://bit.ly/2YLDzTE
This webinar will take you through the story of a CMO preparing for the manufacture of a Commercial Antibody Drug Conjugate (ADC).
Join us to learn about how we grew as a CMO to develop a Commercial ADC program. We will walk through the full timeline from development, process risk assessment and control strategy development and validation, finishing off with preparation for a Commercial ADC Pre-Approval Inspection Audit.
In this webinar you will learn how to:
• Properly structure your development work
• Perform a thorough process risk assessment
• Prepare for pre-approval inspection
Ko services brochure-online-hi-jan2021bSteve Brough
• Fragment Libraries
• Screening compounds
• Large collection of building blocks and intermediates
• PROTACs
• Custom and contract synthesis
• Scale up and route development
• Stable label synthesis
The document discusses Thermo Scientific's leadership in serving science through analytical instruments, equipment, reagents, software and services. It highlights the company's size and scale, unmatched capabilities, portfolio of leading brands, and mission to make the world healthier, cleaner and safer. Key strengths include global industry leadership, ability to continuously invest in growth opportunities through R&D, and an excellent track record of financial performance. New products are presented for applications such as sample preparation, analysis, and data interpretation.
Presentation highlighting Alkermes high potency capabilities in solid oral dosage manufacture. Included in the presentation is a case study on our success tech-transferring a highly potent compound for a large pharma company.
Anecto's ISO 17025 accredited test facility provides world class support to product developers, designers and manufacturers. The state of the art laboratory is supported by technologists and engineers who also design and manufacture specialist products and support customer's warranty programmes.
With over 12 years experience as a company providing Product and Packaging Testing, Consultancy, Support, Bespoke Test Equipment and Protocol Development to the Medical Device Industry Anecto understands and responds to those challenges.
Anecto have a totally up to date knowledge of, understanding of and adherence to the pertinent regulations and standards stipulated by the FDA, the European Medical Device Directive, ISO 11607. We also understand that our clients successful compliance may require a combination of these and other relevant regulation depending on where in the world the product is to be distributed
Extractables profiles for chromatography resins - adapted approach of upcomin...MilliporeSigma
Watch the webinar here: https://bit.ly/36JaZpx
In biopharmaceutical industry there is a trend towards comprehensive risk assessments of drug manufacturing processes. Extractables studies for chromatography resins based on the adapted requirements of the upcoming USP <665> support risk evaluation for your specific chromatography steps.
In this webinar, you will learn about:
- Study design for extractables profiles of chromatography resins
- The new category Emprove® Chromatography
- Communication of extractables data as part of Emprove® Dossiers
Description:
Detailed information on any component or material in contact with the drug substance/ product is required to conduct a compreshensive risk assessment of a biopharmaceutical manufacturing process. No explicit guidelines providing required testing procedures for chromatography steps are in place yet. In the upcoming USP <665> chapter chromatography steps are in focus as well as any other plastic or polymeric component and can as such assessed as to the described criteria. To support our chromatography resin users an adapted extractables study approach was developed. The webinar will demonstrate our study design and the communication of the extractables profiles within our Emprove® Program.
The document discusses guidelines from the International Council for Harmonization (ICH) regarding stability testing of drug substances and products. It provides an overview of the ICH Q1 series of guidelines, which address stability testing, including specifications for testing protocols, storage conditions and minimum data requirements. The guidelines provide recommendations for conducting long-term, intermediate and accelerated stability studies to evaluate the impact of various stress conditions like temperature, humidity and light on drug substances and products. The goal is to ensure quality, safety and efficacy over the proposed shelf-life.
EU GMP Annex 1 – Implications on Filtration and Single Use Technology by Soma...MilliporeSigma
The draft EU GMP Annex 1 provides additional guidance on sterile filtration and single-use systems. It emphasizes minimizing contamination risks through engineering controls like preassembled equipment. It recommends considering a second sterile filter immediately before filling due to filtration risks. It also provides more specific recommendations around filter selection, validation, and system design to ensure sterility and product quality.
Hot melt extrusion with PVA – solubility enhancement, supersaturation perform...Merck Life Sciences
Hot melt extrusion has successfully emerged as an innovative manufacturing technology in pharmaceutical industry for the creation of amorphous solid dispersions (ASDs).
In this webinar you will learn about the potential of hot melt extrusion to overcome challenges in API solubility and bioavailability by using polyvinyl alcohol (PVA) as a matrix polymer. We will provide an overview about different types of solid dispersions and their evolution in the pharmaceutical field. A brief introduction in hot melt extrusion processing will be given as well as actual formulation trends. You will get insights in potential down-stream options to create your final dosage form and you will gain ideas on how to speed up your formulation development.
A detailed background of PVA will be provided including its physical properties as well as its regulatory status. PVA is more than a polymer. Due to its amphiphilic structure it has the potential to improve the supersaturation of low soluble APIs and to prevent precipitation after release. This highlights the versatility of PVA as an advanced polymer for HME applications and we will guide you through our latest research activities so that you can leverage our knowledge to improve your formulations.
This webinar includes:
- The current status and further potential of HME in pharmaceutical industry
- Advantages of PVA in the field of ASDs: Solubility improvement, impact on supersaturation potential, stability data generated on sample formulations & downstream options
- Deep dive into latest research activities: Permeation studies with Caco-2 cell membranes, pH shift studies to investigate supersaturation potential, ongoing research activities to get to know a more detailed understanding of matrix systems and their intermolecular interactions
In this webinar, you will learn:
- which potential hot melt extrusion has, to overcome challenges in API solubility and bioavailability by using polyvinyl alcohol (PVA)
- why PVA is more than just a polymer
- how to create your final dosage form and speed up your formulation development
Bluetech provides the whole solution for your water purifier, including designing, manufacturing, selling and service of water filter products. Product range covers water filter pitcher, faucet filter, shower filter, refrigerator filter, etc.
2nd Annual Proactive GCP Compliance, April 2011, Arlington, VAExL Pharma
The document is an invitation and program for the 2nd annual "Proactive GCP Compliance" conference organized by Exl Pharma. The key details are:
1) The conference will take place from April 4-6, 2011 in Arlington, Virginia and focuses on helping attendees address GCP compliance challenges from a strategic level through sessions led by over 30 experts from major pharmaceutical companies.
2) It provides an opportunity for senior clinical quality and compliance professionals to benchmark their strategies, learn about new FDA and global regulatory requirements, and share experiences.
3) The program includes keynotes from the FDA, panels on industry responses to regulatory changes, and breakout sessions on topics like continuous quality improvement, risk
Fast-track solutions to address challenges with Host Cell Proteins in early d...Merck Life Sciences
Watch this webinar here: https://bit.ly/3fFRXDb
This webinar illustrates a customer case study about the challenges related to the removal of Host Cell Proteins from bioreactor harvest, the selected fast-track approach and outcome.
Our customer had one month to reduce the level of HCPs in the bioreactor harvest prior to a production run to supply drug substance for a scheduled Phase 1 clinical trial. The high level of HCPs (1,000,000 in the harvest and 700 ppm at the end of purification) unfavorably impacted the planned clarification process and subsequent downstream steps.
The goal was to reduce the level of HCPs to maximum of 300 ppm at the end of process purification and ensure clarification of the entire 2000L harvest.
In this webinar, you will learn about:
- Challenges with Host Cell Proteins
- Fast-Track Approach using caprylic acid precipitation followed by filtration using Clarisolve® filters
- The impact of Design of Experiment
Paragon Scientific Limited specialise in the production of premium quality reference materials that include Density, Flash Point, Liquid Colour, Refractive Index, TAN/TBN and Viscosity standards.
Founded in 1994, Paragon have developed an international reputation synonymous with quality, prompt delivery, affordability, and first class customer service. A combination of advanced manufacturing techniques, the use of Primary laboratory test equipment and acute attention to detail enables Paragons to produce reference materials with some of the lowest levels of uncertainty of measurement available. Paragon's products are used in multiple industries throughout the world.
Paragon Scientific Ltd. Founded in 1994, we have developed an international reputation synonymous with quality, prompt delivery,
affordability and first class customer service. We are committed to develop, manufacture and supply the highest quality standards and reference materials available in the marketplace. We believe that this approach combined with key attention to customer service, technical support and prompt delivery is key to our business success.
The document discusses the role of laboratories in the petroleum industry. It outlines how laboratories ensure quality control through routine testing of raw materials, process streams, and finished products. This includes testing properties like density, salt content, water content, viscosity, sulfur content, and metals content. Laboratories also perform troubleshooting, process optimization, and product certification activities. Their work is important for monitoring performance, ensuring product specifications are met, and solving quality problems.
Honeywell offer a wide range of Research Chemicals under their own brands Burdick & Jackson™, Fluka™, Honeywell™,Riedel-de-Haën™, Chromasolv™, Hydranal™, LabReady™ Blends, TraceSLECT™. Covering all applications, including, Bioanalysis, Biosynthesis, Chemical Synthesis, Chromatography, Electrophoresis, Karl Fischer Titration, Octane Determination, Spectroscopy, Titration, Trace Analysis and Wet Chemistry.
David Norris Analytical Laboratories Ltd is a privately owned company established in 2005 that offers specialist formulation storage stability trials and analytical services. The company aims to provide high quality analytical services in an efficient and cost effective manner. They are GLP compliant and offer a range of formulation and technical material storage stability tests to meet various international regulatory requirements. Their services include stability testing under various storage conditions as well as analysis of properties, impurities, and breakdown products.
Appreciated by customers across the nation for supplying, trading and wholesaling a broad array of high quality pharmaceutical hygiene & cleanRoom
products, June Enterprises started its operations in December 2013.
In a short span of time, the company expanded its breadth of operations to provide CleanRoom Products to the Indian pharmaceutical industry &
neighboring countries.
The product range offered by June Enterprises includes: – Sterilization Monitoring & Validation Products, ATCC Culture, Cleanroom Garments &
Accessories, Cleanroom Supplies, Critical Cleaning Products, Products for Food & Facilities, Sterilization Packaging & Sealing Products, Products for
Stores & Warehouses, USP Class Silicone Tubing among others.
In order to ensure high standards of quality, the offered range of Cleanroom Products is procured and sourced from trusted and reliable Leaders in their
® ® respective product ranges for example Sterilization Products by Mesa Labs, Cleaning & disinfectants by Contec & ATCC by Microbiologics.
With years of experience, expertise and a proven track-record of helping many companies with its CleanRoom Products & Sterilization needs, June
Enterprises has established an enviable position in the PHARMA, FOOD & HOSPITAL segments.
JUNE Enterprises is an ISO 9001:2015 certified company.
Learn More: https://www.juneenterprises.com/
CoreRx is a dosage form development company specializing in preformulation, formulation development, analytical development, clinical manufacturing, and commercial manufacturing. It has experienced professionals and state-of-the-art facilities. CoreRx focuses on client satisfaction through effective communication, flexibility, speed, and high quality systems. It offers a range of services from preformulation to stability studies to meet clients' drug development needs.
Cavalier Pharma Logistics Group Capabilities & IQP Overview winyard2015Stephen D. Winyard
Cavalier Pharma Logistics provides specialized logistics services for the transportation of pharmaceutical products globally. They excel in shipping time and temperature sensitive drugs, clinical trial supplies, and other goods. Through their specialized services and attention to detail, they aim to provide unique customer solutions and ensure product quality while in transit. They seek to be a global service provider of choice through logistics competency, helping customers gain advantages.
Commercializing antibody-drug conjugates: a CMO’s journeyMerck Life Sciences
Watch the webinar here: https://bit.ly/2YLDzTE
This webinar will take you through the story of a CMO preparing for the manufacture of a Commercial Antibody Drug Conjugate (ADC).
Join us to learn about how we grew as a CMO to develop a Commercial ADC program. We will walk through the full timeline from development, process risk assessment and control strategy development and validation, finishing off with preparation for a Commercial ADC Pre-Approval Inspection Audit.
In this webinar you will learn how to:
• Properly structure your development work
• Perform a thorough process risk assessment
• Prepare for pre-approval inspection
Ko services brochure-online-hi-jan2021bSteve Brough
• Fragment Libraries
• Screening compounds
• Large collection of building blocks and intermediates
• PROTACs
• Custom and contract synthesis
• Scale up and route development
• Stable label synthesis
The document discusses Thermo Scientific's leadership in serving science through analytical instruments, equipment, reagents, software and services. It highlights the company's size and scale, unmatched capabilities, portfolio of leading brands, and mission to make the world healthier, cleaner and safer. Key strengths include global industry leadership, ability to continuously invest in growth opportunities through R&D, and an excellent track record of financial performance. New products are presented for applications such as sample preparation, analysis, and data interpretation.
Presentation highlighting Alkermes high potency capabilities in solid oral dosage manufacture. Included in the presentation is a case study on our success tech-transferring a highly potent compound for a large pharma company.
Anecto's ISO 17025 accredited test facility provides world class support to product developers, designers and manufacturers. The state of the art laboratory is supported by technologists and engineers who also design and manufacture specialist products and support customer's warranty programmes.
With over 12 years experience as a company providing Product and Packaging Testing, Consultancy, Support, Bespoke Test Equipment and Protocol Development to the Medical Device Industry Anecto understands and responds to those challenges.
Anecto have a totally up to date knowledge of, understanding of and adherence to the pertinent regulations and standards stipulated by the FDA, the European Medical Device Directive, ISO 11607. We also understand that our clients successful compliance may require a combination of these and other relevant regulation depending on where in the world the product is to be distributed
Extractables profiles for chromatography resins - adapted approach of upcomin...MilliporeSigma
Watch the webinar here: https://bit.ly/36JaZpx
In biopharmaceutical industry there is a trend towards comprehensive risk assessments of drug manufacturing processes. Extractables studies for chromatography resins based on the adapted requirements of the upcoming USP <665> support risk evaluation for your specific chromatography steps.
In this webinar, you will learn about:
- Study design for extractables profiles of chromatography resins
- The new category Emprove® Chromatography
- Communication of extractables data as part of Emprove® Dossiers
Description:
Detailed information on any component or material in contact with the drug substance/ product is required to conduct a compreshensive risk assessment of a biopharmaceutical manufacturing process. No explicit guidelines providing required testing procedures for chromatography steps are in place yet. In the upcoming USP <665> chapter chromatography steps are in focus as well as any other plastic or polymeric component and can as such assessed as to the described criteria. To support our chromatography resin users an adapted extractables study approach was developed. The webinar will demonstrate our study design and the communication of the extractables profiles within our Emprove® Program.
The document discusses guidelines from the International Council for Harmonization (ICH) regarding stability testing of drug substances and products. It provides an overview of the ICH Q1 series of guidelines, which address stability testing, including specifications for testing protocols, storage conditions and minimum data requirements. The guidelines provide recommendations for conducting long-term, intermediate and accelerated stability studies to evaluate the impact of various stress conditions like temperature, humidity and light on drug substances and products. The goal is to ensure quality, safety and efficacy over the proposed shelf-life.
EU GMP Annex 1 – Implications on Filtration and Single Use Technology by Soma...MilliporeSigma
The draft EU GMP Annex 1 provides additional guidance on sterile filtration and single-use systems. It emphasizes minimizing contamination risks through engineering controls like preassembled equipment. It recommends considering a second sterile filter immediately before filling due to filtration risks. It also provides more specific recommendations around filter selection, validation, and system design to ensure sterility and product quality.
Hot melt extrusion with PVA – solubility enhancement, supersaturation perform...Merck Life Sciences
Hot melt extrusion has successfully emerged as an innovative manufacturing technology in pharmaceutical industry for the creation of amorphous solid dispersions (ASDs).
In this webinar you will learn about the potential of hot melt extrusion to overcome challenges in API solubility and bioavailability by using polyvinyl alcohol (PVA) as a matrix polymer. We will provide an overview about different types of solid dispersions and their evolution in the pharmaceutical field. A brief introduction in hot melt extrusion processing will be given as well as actual formulation trends. You will get insights in potential down-stream options to create your final dosage form and you will gain ideas on how to speed up your formulation development.
A detailed background of PVA will be provided including its physical properties as well as its regulatory status. PVA is more than a polymer. Due to its amphiphilic structure it has the potential to improve the supersaturation of low soluble APIs and to prevent precipitation after release. This highlights the versatility of PVA as an advanced polymer for HME applications and we will guide you through our latest research activities so that you can leverage our knowledge to improve your formulations.
This webinar includes:
- The current status and further potential of HME in pharmaceutical industry
- Advantages of PVA in the field of ASDs: Solubility improvement, impact on supersaturation potential, stability data generated on sample formulations & downstream options
- Deep dive into latest research activities: Permeation studies with Caco-2 cell membranes, pH shift studies to investigate supersaturation potential, ongoing research activities to get to know a more detailed understanding of matrix systems and their intermolecular interactions
In this webinar, you will learn:
- which potential hot melt extrusion has, to overcome challenges in API solubility and bioavailability by using polyvinyl alcohol (PVA)
- why PVA is more than just a polymer
- how to create your final dosage form and speed up your formulation development
Bluetech provides the whole solution for your water purifier, including designing, manufacturing, selling and service of water filter products. Product range covers water filter pitcher, faucet filter, shower filter, refrigerator filter, etc.
2nd Annual Proactive GCP Compliance, April 2011, Arlington, VAExL Pharma
The document is an invitation and program for the 2nd annual "Proactive GCP Compliance" conference organized by Exl Pharma. The key details are:
1) The conference will take place from April 4-6, 2011 in Arlington, Virginia and focuses on helping attendees address GCP compliance challenges from a strategic level through sessions led by over 30 experts from major pharmaceutical companies.
2) It provides an opportunity for senior clinical quality and compliance professionals to benchmark their strategies, learn about new FDA and global regulatory requirements, and share experiences.
3) The program includes keynotes from the FDA, panels on industry responses to regulatory changes, and breakout sessions on topics like continuous quality improvement, risk
Fast-track solutions to address challenges with Host Cell Proteins in early d...Merck Life Sciences
Watch this webinar here: https://bit.ly/3fFRXDb
This webinar illustrates a customer case study about the challenges related to the removal of Host Cell Proteins from bioreactor harvest, the selected fast-track approach and outcome.
Our customer had one month to reduce the level of HCPs in the bioreactor harvest prior to a production run to supply drug substance for a scheduled Phase 1 clinical trial. The high level of HCPs (1,000,000 in the harvest and 700 ppm at the end of purification) unfavorably impacted the planned clarification process and subsequent downstream steps.
The goal was to reduce the level of HCPs to maximum of 300 ppm at the end of process purification and ensure clarification of the entire 2000L harvest.
In this webinar, you will learn about:
- Challenges with Host Cell Proteins
- Fast-Track Approach using caprylic acid precipitation followed by filtration using Clarisolve® filters
- The impact of Design of Experiment
Paragon Scientific Limited specialise in the production of premium quality reference materials that include Density, Flash Point, Liquid Colour, Refractive Index, TAN/TBN and Viscosity standards.
Founded in 1994, Paragon have developed an international reputation synonymous with quality, prompt delivery, affordability, and first class customer service. A combination of advanced manufacturing techniques, the use of Primary laboratory test equipment and acute attention to detail enables Paragons to produce reference materials with some of the lowest levels of uncertainty of measurement available. Paragon's products are used in multiple industries throughout the world.
Paragon Scientific Ltd. Founded in 1994, we have developed an international reputation synonymous with quality, prompt delivery,
affordability and first class customer service. We are committed to develop, manufacture and supply the highest quality standards and reference materials available in the marketplace. We believe that this approach combined with key attention to customer service, technical support and prompt delivery is key to our business success.
The document discusses the role of laboratories in the petroleum industry. It outlines how laboratories ensure quality control through routine testing of raw materials, process streams, and finished products. This includes testing properties like density, salt content, water content, viscosity, sulfur content, and metals content. Laboratories also perform troubleshooting, process optimization, and product certification activities. Their work is important for monitoring performance, ensuring product specifications are met, and solving quality problems.
Honeywell offer a wide range of Research Chemicals under their own brands Burdick & Jackson™, Fluka™, Honeywell™,Riedel-de-Haën™, Chromasolv™, Hydranal™, LabReady™ Blends, TraceSLECT™. Covering all applications, including, Bioanalysis, Biosynthesis, Chemical Synthesis, Chromatography, Electrophoresis, Karl Fischer Titration, Octane Determination, Spectroscopy, Titration, Trace Analysis and Wet Chemistry.
David Norris Analytical Laboratories Ltd is a privately owned company established in 2005 that offers specialist formulation storage stability trials and analytical services. The company aims to provide high quality analytical services in an efficient and cost effective manner. They are GLP compliant and offer a range of formulation and technical material storage stability tests to meet various international regulatory requirements. Their services include stability testing under various storage conditions as well as analysis of properties, impurities, and breakdown products.
Appreciated by customers across the nation for supplying, trading and wholesaling a broad array of high quality pharmaceutical hygiene & cleanRoom
products, June Enterprises started its operations in December 2013.
In a short span of time, the company expanded its breadth of operations to provide CleanRoom Products to the Indian pharmaceutical industry &
neighboring countries.
The product range offered by June Enterprises includes: – Sterilization Monitoring & Validation Products, ATCC Culture, Cleanroom Garments &
Accessories, Cleanroom Supplies, Critical Cleaning Products, Products for Food & Facilities, Sterilization Packaging & Sealing Products, Products for
Stores & Warehouses, USP Class Silicone Tubing among others.
In order to ensure high standards of quality, the offered range of Cleanroom Products is procured and sourced from trusted and reliable Leaders in their
® ® respective product ranges for example Sterilization Products by Mesa Labs, Cleaning & disinfectants by Contec & ATCC by Microbiologics.
With years of experience, expertise and a proven track-record of helping many companies with its CleanRoom Products & Sterilization needs, June
Enterprises has established an enviable position in the PHARMA, FOOD & HOSPITAL segments.
JUNE Enterprises is an ISO 9001:2015 certified company.
Learn More: https://www.juneenterprises.com/
- ChemTreat is a water treatment company founded in 1968 that has experienced annual growth of 13% and has headquarters in Richmond, Virginia and manufacturing facilities across the US and internationally.
- They are one of the largest providers of water treatment products and services in the industry and are dedicated solely to industrial water treatment.
- ChemTreat prides itself on the experience of its field representatives, low turnover rates, and focus on long-term customer relationships.
ProGammaScience Corporation is a consulting firm based in Montreal that has been providing quality assurance, regulatory affairs, and technical operations services to the pharmaceutical industry since 1985, including assistance with submissions, GMP compliance, analytical method validation, product development, and technical training. The company aims to deliver excellent client service and documentation support at the best possible cost through its team of qualified professionals. Some of ProGammaScience's clients include major pharmaceutical companies like Abbott, AstraZeneca, Merck, Novartis, and Pfizer.
produces equipment to customers exact requirements, from conception to completion, taking active role in helping to ensure that the equipment proposed will meet the Specifications ,Budget & ON time Delivery.
facebook:https://www.facebook.com/IsotechTechnology
YT Sub Link: https://bit.ly/isotech-YT-channel
https://in.linkedin.com/company/isotech-technology
Isotech pl : https://www.isotechpl.com/
How to Choose the Best Testing Lab in the UAE.pdfsandeepmetsuae
The best testing lab in the UAE stands out for its advanced technology, comprehensive services, and adherence to international standards. Dubai Central Laboratory and SGS Gulf Limited are prime examples, offering precise and reliable testing across various sectors, including environmental analysis, food safety, and industrial inspections.
How to Choose the Best Testing Lab in the UAE.pptxsandeepmetsuae
The best testing lab in the UAE stands out for its advanced technology, comprehensive services, and adherence to international standards. Dubai Central Laboratory and SGS Gulf Limited are prime examples, offering precise and reliable testing across various sectors, including environmental analysis, food safety, and industrial inspections. These labs are renowned for their state-of-the-art equipment and expert teams, ensuring accurate results and helping businesses maintain high-quality standards and regulatory compliance.
Manufacturer of wide range of Aerosol products for the use of Home and hygiene , Healthcare , personal care , Industrial , Cosmetic , pharmaceutical , pain management etc
This document describes the reliability services offered by Reliability Resources, including reliability consulting, education, testing, and failure analysis. They provide reliability engineering services throughout a product's lifecycle from concept to manufacturing. Key services mentioned include HALT/HASS testing in environmental test chambers, traditional testing like vibration and shock, reliability consulting and program development, and failure analysis to identify root causes of product failures. The document promotes Reliability Resources as a one-stop shop for all reliability needs.
AmSpec is proud to provide professional and reliable inspection and testing services to its clients, boasting an extensive staff of highly trained and motivated people. With offices throughout the United States and around the world, AmSpec can provide inspection and testing services almost anywhere in the world with the same quality and reliability our customers have come to expect from us.
Greyhound Chromatography's trademarked Q-Range Chromatography Laboratory products include Syringe Filters, Vials, Caps and Closures, Seals., HPLC Pump Spares, HPLC Columns, Capillary Columns, Membrane filters.
Established in 1981,Greyhound Chromatography has been supplying high quality Chromatography consumables to Research and Analysis Laboratories around the world for 40 years. Greyhound's Managing Director, Paul Massie founded the company which operates from its UK warehouse and office facility, located in Birkenhead, Merseyside.
Greyhound supplies Certified Reference Standards and Materials, Research Chemicals; including Solvents and Reagents and Laboratory consumables. New products are constantly added to Greyhound's e-commerce website, be sure to register to the website to view product prices.
Greyhound prides itself on personal service which provides prompt, efficient, cost-effective, safe delivery of all products. With state-of-the art facilities and highly trained staff, Greyhound provides technical advice and distribution of Chromatography consumables across all disciplines. Our service is designed to provide a wide range of products, to help our clients to achieve excellent, cost-effective results. Greyhound manufactures its own range of Capillary Columns, Syringe Filters, SPE Cartridges and HPLC Columns, the 'Q' Range, as well as representing the industry’s best known manufacturers.
By working with the industry’s best known manufacturers we are able to tailor products to customer requirements and distribute products on behalf of 3M, AIT, Biosolve; BP (British Pharmacopeia), Cerilliant; Chem Service (Environmental and Pesticides); Chiron; Chromacol; EP Scientific; Extrasynthese, Gas Arc; Hach Lange, Hamilton; High Purity Standards; Honeywell, IDEX; Jour Research; Larodan Fine Chemicals; Macherey-Nagel; Merck, National Scientific; NIST; Paragon Scientific, PAH Reference Standards; Peak Scientific, Pfaltz and Bauer; Regis Technologies; Rheodyne; RT Corporation; SGE analytical, SGT Filters; Sigma Aldrich, Fluka and Supelco; Silicycle, Swagelok; TCI (Tokyo Chemical Industry); Thermo Scientific, Trajan, Upchurch; USP (United States Pharmacopeia); Vici
Intertek has over 50 years of experience in HVAC/R testing and certification. They work with all major manufacturers and industry associations to test for safety, performance, efficiency and other standards. As technologies evolve, Intertek understands new areas like smart appliances and multi-split systems to help clients launch innovative products globally.
Quality Systems from Basic to Enhanced rev3Kevin Hryclik
This document outlines the components of basic and enhanced quality systems for breweries. It discusses key aspects like raw material management, analytical programs, microbiological monitoring, sanitation, sensory evaluation, packaging quality, pest control, quality holds management, traceability, consumer monitoring, housekeeping, auditing, and quality performance monitoring. The enhanced systems provide more detailed procedures, monitoring, and data collection to improve quality and reduce risk compared to basic systems. The presentation emphasizes that all breweries need a quality program and enhancing basic programs can help reduce the risk of non-compliant product.
KRS Global Biotechnology is a leading outsourcing facility that provides the highest quality sterile and non-sterile pharmaceutical preparations. It has an unrivaled quality assurance program focusing on cGMP and USP standards. KRS is committed to developing quality processes and safety for patients through services like sterile injectables, intravenous admixtures, and topical preparations. It has a state-of-the-art analytical laboratory and uses advanced equipment to test all injectable products for sterility, potency, pH, and endotoxins to ensure the highest standards of safety and effectiveness for patients.
This document is the introduction to the 2015-2016 catalog for Chem Service Inc., which provides analytical and chemical standards. It discusses Chem Service's expertise and leadership in providing high quality analytical standards for laboratories worldwide. The catalog contains an extensive selection of environmental, analytical, and chemical products including over 100 new pesticides and metabolites. It highlights features such as CAS numbers, same-day shipping for orders before 4 PM, and their commitment to customer service and technical support.
- Pharma Soul provides calibration services for various instruments used in process control, laboratories, electricity, dimensions, and validation. It has vast experience calibrating instruments that measure pressure, temperature, electrical values, mass, time, noise, air flow, and more.
- Calibrations are performed in a controlled environment according to ISO guidelines and calibration standards are traceable to national and international standards, providing confidence for audits.
- Pharma Soul's customers include nearly 100 reputed companies throughout India and it has calibrated over 10,000 instruments in the last 2 years. It aims to provide round-the-clock calibration services to meet industry needs.
Similar to Chem Service Inc Pesticide Reference Standards Catalogue (20)
PFAS Testing Solutions from Greyhound Chromatography.
As a global supplier of chromatography consumables and reference standards, Greyhound
Chromatography have brought together in this catalogue, the best products for the analysis of
PFAS compounds from the leading manufacturers in the field.
PFAS (per and polyfluoroalkyl substances) is the collective name for almost 5000 compounds
which have been produced since the 1940s. These compounds are not naturally occurring in
nature so the problems of global pollution are entirely the result of human activity. The utility of
these compounds has resulted in their rapid adoption which has resulted in them being found in
cookware, stain repellents, food packaging, cosmetics, firefighting foams and many
manufacturing processes.
PFAS are known as ‘forever chemicals’ in that they are very persistent in the environment and the
human body, resulting in increasing health risks including damage to immune systems, cancer and
thyroid hormone disruption.
Considerable research has been undertaken to develop products which are specifically suited for
the analysis of PFAS by HPLC, from sample preparation, through to analytical detection.
This brochure brings together many of the leading products used in PFAS analysis, including the
analysis of samples in water, soil, food and beverages as well as serum samples.
PFAS Testing Solutions from Greyhound Chromatography. An overview of the products available that focus specifically on PFAS analysis.
As a global supplier of chromatography consumables and reference standards, Greyhound
Chromatography have brought together in this catalogue, the best products for the analysis of
PFAS compounds from the leading manufacturers in the field.
PFAS (per and polyfluoroalkyl substances) is the collective name for almost 5000 compounds
which have been produced since the 1940s. These compounds are not naturally occurring in
nature so the problems of global pollution are entirely the result of human activity. The utility of
these compounds has resulted in their rapid adoption which has resulted in them being found in
cookware, stain repellents, food packaging, cosmetics, firefighting foams and many
manufacturing processes.
PFAS are known as ‘forever chemicals’ in that they are very persistent in the environment and the
human body, resulting in increasing health risks including damage to immune systems, cancer and
thyroid hormone disruption.
Considerable research has been undertaken to develop products which are specifically suited for
the analysis of PFAS by HPLC, from sample preparation, through to analytical detection.
This brochure brings together many of the leading products used in PFAS analysis, including the
analysis of samples in water, soil, food and beverages as well as serum samples.
PFAS Focus presented by Greyhound Chromatography . Details of products that are available, for laboratory use, for the testing and analysis of PFAS.
Products available from Greyhound Chromatography under their own brand the Q-Range, Reference Standards and Materials from Wellington Laboratories and Chromatography consumables from Macherey-Nagel.
Reference Standards and materials are also available from Chem Service Inc., High Purity Standards and HPC.
Greyhound’s extensive range covers all areas of Environmental, Petrochemical, Food, Fragrance, Forensics, Chemical and Pharmaceutical analysis, holding stock of many popular products for prompt delivery via our extensive logistics network.
Greyhound prides itself on personal service which provides prompt, efficient, cost-effective, safe delivery of all products. With state-of-the art facilities and highly trained staff, Greyhound provides technical advice and distribution of Chromatography consumables across all disciplines. Our service is designed to provide a wide range of products, to help our clients to achieve excellent, cost-effective results. Greyhound manufactures its own range of Capillary Columns, Syringe Filters, SPE Cartridges and HPLC Columns, the 'Q' Range, as well as representing the industry’s best known manufacturers.
Established in 1981, Greyhound Chromatography has been supplying high quality Chromatography consumables to Research and Analysis laboratories around the world for over 40 years. Greyhound's Managing Director, Paul Massie, founded the company which operates from its UK warehouse and office facility, located in Birkenhead, Merseyside.
Greyhound Chromatography is a leading global manufacturer and distributor of the highest quality chromatography columns, consumables, certified reference standards and materials, research chemicals, solvents, reagents and laboratory consumables available today.
Greyhound supplies scientists working in all disciplines, including HPLC and Gas Chromatography. Greyhound Chromatography is probably the leading single source of chromatography products and chemical standards anywhere in the world.
What are Reference Standards?
A pharmaceutical reference standard is a highly characterized material
suitable to test the identity, strength, quality and purity of substances
for pharmaceutical use and medicinal products.
The reference standard is the test, combination of tests, or
procedure that is considered the best available method of categorizing
participants in a study of diagnostic test accuracy as having or not
having a target condition.
Greyhound Chromatography supplies a large range of pre-prepared
and custom made chromatography standards from a number of
leading manufacturers, including Chem Service, Cifga, Extrasynthese,
High Purity Standards, Honeywell (Fluka), Laradon, Merck (Sigma
Aldrich, Supelco), Paragon Scientific and Wellington Laboratories.
Greyhound Chromatography is delighted to represent Merck /Sigma as a principal
distributor and all products from the company are available through Greyhound. Sigma
Aldrich Laboratory & Production Materials, including Supelco Analytical Products developed
by analytical chemists covers a broad range of analytical solutions and every product
undergoes meticulous quality control to maintain the integrity of your testing protocols.
How to Order MERCK/Sigma Aldrich Products from Greyhound Chromatography
MERCK / Sigma Aldrich products can be found under the MERCK portfolio. This is available on
our secure website—you can browse the current product list HERE. Please send your quote
request to sales@greyhoundchrom.com There may be a discount available for bulk
purchases or repeat orders.
High Purity Standards has proudly served the scientific community
for the past twenty years with high quality spectrometric
standards and reference materials for AAS, ICP, ICP-MS, GC,
GC-MS and IC, and has now expanded their stocked reference
materials to include ISO Guide 34 multi-component organic
reference materials.
Approximately one half of High Purity Standards' business is in the
preparation of custom blends and difficult to prepare special
mixtures.
New products of note include expanded spiked filter products in
addition to organic reference materials designed to meet EPA
testing requirements and additional products from customer
requests.
Browse High Purity Standards HERE. There may be a discount
available for bulk purchases or repeat orders, please request a
quotation by emailing sales@greyhoundchrom.com
Wellington are committed to the distribution of quality products as well as the
maintenance of excellent customer service. In fact, in order to provide you with the best
possible service, Wellington Laboratories now have three ISO certifications (ISO
9001:2015, ISO/IEC 17025:2005, and ISO 17034:2016) which cover all aspects of
planning, production, testing, distribution, and post-distribution service. These certificates
allow us to monitor and maintain the highest level of quality and service .
Is Vaping the right solution for giving up smoking nicotine products?
Is Vaping just a case of smoke and mirrors?
Should we be concerned about health issues caused by vaping?
With the vast increase in Vaping being led by the thought
it can stop a users addiction of smoking, do we really have
all the facts we need to determine if this is the truth?
Although e-cigarettes date back to being invented in the
1920’s, it wasn’t until the mid 2000’s that a Chinese
company, owned by pharmacist Hon Lik, created the first
modern vaping device to be sold on the high street.
Recently there has been a lot of media coverage regarding
e-cigarettes and the affect that they have on human
health, there is almost no proven scientific evidence to
say that vaping is better for people than smoking.
We are all aware that smoking is able to cause many known
illnesses and can commonly lead to death, but new stories
have come to light recently, show that vaping has a huge
detrimental effect in the same way that smoking does.
Laws have been implemented in the US since 2016 regarding
the use of vape devices which states it is illegal to
sell e-cigarettes to minors but advertising to adults is
still permitted. There isn’t as much concern that vaping
will effect children in the UK in the same way, as we
have strict limits on the levels of nicotine that can be
included in e-liquids, whereas the US do not.
Considering e-cigarettes were introduced to the market as
a less harmful alternative to smoking, there has been an
increased concern that people have taken up vaping
although they never smoked to begin with.
Electronic Cigarettes (A vape) are small devices that
use different flavoured nicotine oils, also known as
e-juices, to create smoke in a vapour form.
A vaping device does not include or contain tobacco and
therefore doesn’t allow you to produce carbon monoxide
or tar that can be formed from resins that are active
in cigarettes.
How is vape oil (e-juice) made?
Vape juices are generally made by mixing together
different flavours and nicotine with a solvent which
is usually propylene glycol.
Sometimes people will optionally use vegetable
glycerine. The solvent that is used within the mix is
the main chemical that is included in the vape oil.
Propylene glycol is an organic chemical compound that
is most commonly used within foods as an additive to
improve the flavour, colour or texture of different
products.
Currently in the UK, there is estimated to be 3.6 million people who are vaping. It is becoming
more and more common that people have taken up vaping in place of their addictive cigarette
habit, as they believe that this will be “better” for them in the long run. It has been proven
that if there is repeated high exposure to this vapour then very harmful risks could occur.
Recently there have been many cases related to e-cigarettes and the effects that they can cause.
Chem Service, Inc. produces high purity standards for use as reference
materials and for other laboratory purposes. More than 95% of the Standards Grade
materials have a certified purity of 98.0% or greater and do not require purity
corrections when preparing solutions for use with EPA, USTM, UST, and numerous
other international methods. You can trust that Chem Service high purity standards
are a quality product.
Why is Pesticide Testing Important?
Pesticides are an effective tool used by farmers all across the globe to prevent insects, rodents and other pests from
eating or spoiling their crops. Although, because these chemical compounds are deadly to these pests, it has been
important to ensure that pesticides do not have poisonous effects past insects to humans and other aspects of nature.
However, it can be difficult for communities to police pesticides and it is not as effective to test pesticide use after it
has already been applied to a field or farm. For these reasons, there have been a number of international bodies that
have joined together to create testing guidelines to ensure that the pesticides used in the U.S., Australia, Africa and
anywhere else will not result in unwanted repercussions for humans nearby. Pesticide users and manufacturers can
use certified and approved standards to check whether their pesticides meet quality and specification requirements
to work effectively without harmful consequences.
Countries Work Towards a Common Goal
Since the 1960 formation of the Convention on the Organization for Economic Co-operation and Development,
countries including the U.S, U.K., Mexico, Japan, Chile and Germany have created a set of pesticide testing protocols.
The OECD pointed to nearly 100 testing methods for the testing of these chemicals. The international group both
creates guidelines for pesticide uses as well as tests the residue of pesticides in OECD and non-OECD countries to
study their effects and determine further usage plans.
Separate from the OECD, the Collaborative International Pesticide Analytical Council, the Food and Agriculture
Organization of the United Nations, and the World Health Organization also work to regulate safe pesticide use on an
international scale. In a 2005 report published by all three organizations outlining the quality to be used in national
laboratories, they explained the importance of using standards from approved international providers.
Protecting Bees From Pesticides
As far as humans are concerned, bees are one of the most important
insects. Though they aren't the only type of bug that pollinates plants,
they are one of the most common. Bees ensure that plants produce
fruits and vegetables. Without them, whole industries would die and
many would be without a source of food. However, pesticides meant to
rid crops of other harmful insects are having an adverse effect on bee
populations around the world.
PFAS (per- and polyfluoroalkyl
substances), known as “forever
chemicals” are found in everyday
objects. Food Packaging, paints,
cosmetics, wood lacquers, sealants ,
solar panels, fire fighting foams,
artificial grass and many more
seemingly innocent products.
Generally used to prevent corrosion
and make products waterproof and
stain-resistant they are present in our
everyday life. Unfortunately they do
not break down in our environment
and as a consequence are “forever
present”. Greyhound Chromatography provides a wide range of Chromatography related products for testing and analysis of PFAS and many other 'forever chemicals'.
Are all PFAS toxic to humans?
This is a question that remains to be answered.
Research over many years will provide the data
needed to analyse the impact PFAS has on the
environment. Some PFAS, sometimes used in
construction materials are not released into the
air or water table when it rains but they are
released when buildings are demolished and the
debris is sent to landfill.
Some PFAs are of a more immediate concern as they are released into the environment when they
are used or when they come into contact with water. Small residual PFAS molecules wash off
easily and are carried to the soil, air and water very quickly. Many short-chain PFAS dissolve in
water. Gradually, over time, the PFAS sinks to the depths of oceans and rivers, settles in the
sediment and becomes a concern as marine life feeds on plants and other animals that are in the
sediment. Some PFAS such as PFOA act like detergents, they repel water and rise back to the
surface, they are then released into the atmosphere as droplets. Some scientists believe that spray
from the oceans is the biggest source of atmospheric PFAS.
Wellington Laboratories has been committed to providing high quality reference standards and exceptional customer service since its inception in 1980.
The primary source of Standards for EPA Methods 23, 513, 1613, 1668, 8280, 8290, European Method EN-1948 and World Health/EPA Standards, C13 and Native Dioxins, Furans, PCBs and Brominated Diphenyl Ethers, Brominated Dioxins and Furans, Methylated PCDDs and PCDFs, Fluorinated Compounds and more.
Greyhound Chromatography provides a wide range of PFAS related products for testing and analysis.
Wellington Laboratories has been committed to providing high quality reference standards and exceptional customer service since its inception in 1980.
The primary source of Standards for EPA Methods 23, 513, 1613, 1668, 8280, 8290, European Method EN-1948 and World Health/EPA Standards, C13 and Native Dioxins, Furans, PCBs and Brominated Diphenyl Ethers, Brominated Dioxins and Furans, Methylated PCDDs and PCDFs, Fluorinated Compounds and more. Wellington Laboratories' offer a large range of native and mass-labelled per- and poly-fluorinated compounds.
Chem Service, Inc. produces high purity standards for use as reference materials and for other laboratory purposes. More than 95% of the Standards Grade materials have a certified purity of 98.0% or greater and do not require purity corrections when preparing solutions for use with EPA, USTM, UST, and numerous other international methods. You can trust that Chem Service high purity standards are a quality product.
Established in 1962 Chem Service is the largest independent supplier of Analytical Reference Materials and the original source of small quantities of organic chemicals. Chem Service also has over 2,000 Pesticide Standards, including Pesticide Standards for Cannabis in its catalogue. Chem Service offers Custom made Standards manufactured to your specific requirements, all standards are accredited to ISO 17043:2016; ISO/IEC 17025:2005; ISO 9001:2015 Quality Management System.
Over 95% of Chem Services’ neat Standards Grade materials have a purity of 98.0% or greater.
Chem Services’ worldwide customers are found in the chemical, government, food quality, agricultural and life science research communities.
Chem Service's range of Certified Reference Standards are available from Greyhound Chromatography and Allied Chemicals for fast delivery all over the world.
This document provides information on gas purifiers from Greyhound Chromatography that are designed to remove contaminants from carrier gases used in gas chromatography and mass spectrometry. It describes cartridge-style gas purifiers that contain adsorbent-packed filters in polycarbonate housings connected to base plates for easy filter replacement. Individual filters are available to remove oxygen, moisture, or hydrocarbons. Combination filters remove multiple contaminants. Larger "Big Trap" purifiers are also described. The document explains how purifiers improve analysis quality by reducing baseline noise, column degradation, and other issues caused by contaminated gases.
This document provides information about spare parts for HPLC pumps from various manufacturers that are available from Greyhound Chromatography. It lists pump models from companies like Agilent, Beckman, Dionex, Gilson, Knauer, Waters and others. For each pump model, it provides the original equipment manufacturer (OEM) part number and the corresponding Greyhound part number for replacement pistons, seals, check valves and other spare parts. The document encourages customers to purchase spare parts from Greyhound to save costs compared to the OEM and avoid service calls.
Greyhound Q-Fil Membrane Filters are one of the worlds most popular ranges of Membrane Filters for environmental, industrial, water, food, chemical and biotechnology laboratories.
These high quality membranes are manufactures to the highest specifications to meet the varying requirements of the scientific community.
The Merlin Microseal from greyhound Chromatography is a microvalve alternative to the conventional silicone rubber septa used in Gas Chromatography (GC). Its unique design gives it high pressure capability and resisance to wear which results in long life and excellent chromatographic performance. The microseal is available for all major GC manufacturer's instruments.
Q-range Crimpers and Decappers are the latest development in ergonomic design of manual and electronic devices and transform the standards of vial crimping and decapping. Save time and eliminate repetitive strain when crimping multiple vials. For high volume users, the High Power Crimping Tool will store multiple programmes for different caps and seals and accommodates various sizes of interchangeable jaw sets to increase productivity and ease of use.
For Over 35 years Wellington Laboratories Inc. has been internationally recognised as a trusted source of high quality reference standard solutions for use in environmental/analytical testing and toxicological research. Wellington Laboratories offers an extensive inventory of individual certified reference standards and solution mixtures of native and mass-labelled halogenated organic compounds including polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, polychlorinated biphenyls, halogenated flame retardants and perfluorinated compounds. Wellington Laboratories also offer a variety of calibration sets and support solutions designed to be used for common regulatory methods or modified in-house methods.
Wellington’s Reference Standards are used mainly in Environmental/analytical testing and toxicological research. Wellington offers an extensive inventory of individual certified reference standards and solution mixtures of native and mass-labelled halogenated organic compounds including polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, polychlorinated biphenyls, halogenated flame retardants and perfluorinated compounds. Wellington also offer a variety of calibration sets and support solutions designed to be used for common regulatory methods of modified in-house methods.
This document provides information on HPLC pumps from Greyhound Chromatography, including specifications and ordering details for various pump models. It describes pumps for isocratic and gradient applications across a range of flow rates and pressures. Models include single piston and dual piston pumps, as well as constant pressure and high pressure pumps. Replacement parts and accessories are also listed. The document aims to help customers select the appropriate pump for their HPLC system and application needs.
The extensive range of Q-Range autosampler and storage vials and caps, caters for almost every conceivable storage requirement from microlitre to millilitre volumes, in clear or amber glass and plastic materials. Complete with screw, crimp and snap top closures and standard or speciality septa and liners. Our products are designed to suit all the major Instrument manufacturers' equipment, including Agilent, Hitatchi, PerkinElmer, Shimadzu, Thermo Scientific, Varian, Waters etc..
Adam Equipment started in 1972 with the goal to provide quality weighing equipment and services at affordable prices, offering superior value to its customers. Adam scales and balances are sold throughout the world, supported by a diversified network of distributors. Adam Equipment and OEM branded products are used by various customers daily. You will see Adam products in the scientific, medical, educational, industrial, manufacturing and retail sectors.
MACHEREY-NAGEL is a globally operating company with stable growth. In the recent years, the annual turnover exceeded 100 million Euros.
Our comprehensive portfolio includes products for Filtration, Rapid Tests, Water Analysis, Chromatography, and Bioanalysis. We are proud to carry more than 20,000 products designed and manufactured to fit your individual needs.
With more than 470 highly qualified and experienced employees MACHEREY-NAGEL provides the best and most convenient service to our customers. 10 % of our staff have advanced degrees in the fields of Chemistry, Biology, Physics and Engineering, working in our research department on solutions to make your daily laboratory work easier.
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Discovery of An Apparent Red, High-Velocity Type Ia Supernova at 𝐳 = 2.9 wi...Sérgio Sacani
We present the JWST discovery of SN 2023adsy, a transient object located in a host galaxy JADES-GS
+
53.13485
−
27.82088
with a host spectroscopic redshift of
2.903
±
0.007
. The transient was identified in deep James Webb Space Telescope (JWST)/NIRCam imaging from the JWST Advanced Deep Extragalactic Survey (JADES) program. Photometric and spectroscopic followup with NIRCam and NIRSpec, respectively, confirm the redshift and yield UV-NIR light-curve, NIR color, and spectroscopic information all consistent with a Type Ia classification. Despite its classification as a likely SN Ia, SN 2023adsy is both fairly red (
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−
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)
∼
0.9
) despite a host galaxy with low-extinction and has a high Ca II velocity (
19
,
000
±
2
,
000
km/s) compared to the general population of SNe Ia. While these characteristics are consistent with some Ca-rich SNe Ia, particularly SN 2016hnk, SN 2023adsy is intrinsically brighter than the low-
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Ca-rich population. Although such an object is too red for any low-
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cosmological sample, we apply a fiducial standardization approach to SN 2023adsy and find that the SN 2023adsy luminosity distance measurement is in excellent agreement (
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1
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) with
Λ
CDM. Therefore unlike low-
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Ca-rich SNe Ia, SN 2023adsy is standardizable and gives no indication that SN Ia standardized luminosities change significantly with redshift. A larger sample of distant SNe Ia is required to determine if SN Ia population characteristics at high-
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truly diverge from their low-
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counterparts, and to confirm that standardized luminosities nevertheless remain constant with redshift.
Immersive Learning That Works: Research Grounding and Paths ForwardLeonel Morgado
We will metaverse into the essence of immersive learning, into its three dimensions and conceptual models. This approach encompasses elements from teaching methodologies to social involvement, through organizational concerns and technologies. Challenging the perception of learning as knowledge transfer, we introduce a 'Uses, Practices & Strategies' model operationalized by the 'Immersive Learning Brain' and ‘Immersion Cube’ frameworks. This approach offers a comprehensive guide through the intricacies of immersive educational experiences and spotlighting research frontiers, along the immersion dimensions of system, narrative, and agency. Our discourse extends to stakeholders beyond the academic sphere, addressing the interests of technologists, instructional designers, and policymakers. We span various contexts, from formal education to organizational transformation to the new horizon of an AI-pervasive society. This keynote aims to unite the iLRN community in a collaborative journey towards a future where immersive learning research and practice coalesce, paving the way for innovative educational research and practice landscapes.
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Neutralizing antibodies, pivotal in immune defense, specifically bind and inhibit viral pathogens, thereby playing a crucial role in protecting against and mitigating infectious diseases. In this slide, we will introduce what antibodies and neutralizing antibodies are, the production and regulation of neutralizing antibodies, their mechanisms of action, classification and applications, as well as the challenges they face.
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Ozturkcan, S., Berndt, A., & Angelakis, A. (2024). Mending clothing to support sustainable fashion. Presented at the 31st Annual Conference by the Consortium for International Marketing Research (CIMaR), 10-13 Jun 2024, University of Gävle, Sweden.
Evidence of Jet Activity from the Secondary Black Hole in the OJ 287 Binary S...Sérgio Sacani
Wereport the study of a huge optical intraday flare on 2021 November 12 at 2 a.m. UT in the blazar OJ287. In the binary black hole model, it is associated with an impact of the secondary black hole on the accretion disk of the primary. Our multifrequency observing campaign was set up to search for such a signature of the impact based on a prediction made 8 yr earlier. The first I-band results of the flare have already been reported by Kishore et al. (2024). Here we combine these data with our monitoring in the R-band. There is a big change in the R–I spectral index by 1.0 ±0.1 between the normal background and the flare, suggesting a new component of radiation. The polarization variation during the rise of the flare suggests the same. The limits on the source size place it most reasonably in the jet of the secondary BH. We then ask why we have not seen this phenomenon before. We show that OJ287 was never before observed with sufficient sensitivity on the night when the flare should have happened according to the binary model. We also study the probability that this flare is just an oversized example of intraday variability using the Krakow data set of intense monitoring between 2015 and 2023. We find that the occurrence of a flare of this size and rapidity is unlikely. In machine-readable Tables 1 and 2, we give the full orbit-linked historical light curve of OJ287 as well as the dense monitoring sample of Krakow.
TOPIC OF DISCUSSION: CENTRIFUGATION SLIDESHARE.pptxshubhijain836
Centrifugation is a powerful technique used in laboratories to separate components of a heterogeneous mixture based on their density. This process utilizes centrifugal force to rapidly spin samples, causing denser particles to migrate outward more quickly than lighter ones. As a result, distinct layers form within the sample tube, allowing for easy isolation and purification of target substances.
Microbial interaction
Microorganisms interacts with each other and can be physically associated with another organisms in a variety of ways.
One organism can be located on the surface of another organism as an ectobiont or located within another organism as endobiont.
Microbial interaction may be positive such as mutualism, proto-cooperation, commensalism or may be negative such as parasitism, predation or competition
Types of microbial interaction
Positive interaction: mutualism, proto-cooperation, commensalism
Negative interaction: Ammensalism (antagonism), parasitism, predation, competition
I. Mutualism:
It is defined as the relationship in which each organism in interaction gets benefits from association. It is an obligatory relationship in which mutualist and host are metabolically dependent on each other.
Mutualistic relationship is very specific where one member of association cannot be replaced by another species.
Mutualism require close physical contact between interacting organisms.
Relationship of mutualism allows organisms to exist in habitat that could not occupied by either species alone.
Mutualistic relationship between organisms allows them to act as a single organism.
Examples of mutualism:
i. Lichens:
Lichens are excellent example of mutualism.
They are the association of specific fungi and certain genus of algae. In lichen, fungal partner is called mycobiont and algal partner is called
II. Syntrophism:
It is an association in which the growth of one organism either depends on or improved by the substrate provided by another organism.
In syntrophism both organism in association gets benefits.
Compound A
Utilized by population 1
Compound B
Utilized by population 2
Compound C
utilized by both Population 1+2
Products
In this theoretical example of syntrophism, population 1 is able to utilize and metabolize compound A, forming compound B but cannot metabolize beyond compound B without co-operation of population 2. Population 2is unable to utilize compound A but it can metabolize compound B forming compound C. Then both population 1 and 2 are able to carry out metabolic reaction which leads to formation of end product that neither population could produce alone.
Examples of syntrophism:
i. Methanogenic ecosystem in sludge digester
Methane produced by methanogenic bacteria depends upon interspecies hydrogen transfer by other fermentative bacteria.
Anaerobic fermentative bacteria generate CO2 and H2 utilizing carbohydrates which is then utilized by methanogenic bacteria (Methanobacter) to produce methane.
ii. Lactobacillus arobinosus and Enterococcus faecalis:
In the minimal media, Lactobacillus arobinosus and Enterococcus faecalis are able to grow together but not alone.
The synergistic relationship between E. faecalis and L. arobinosus occurs in which E. faecalis require folic acid
The cost of acquiring information by natural selectionCarl Bergstrom
This is a short talk that I gave at the Banff International Research Station workshop on Modeling and Theory in Population Biology. The idea is to try to understand how the burden of natural selection relates to the amount of information that selection puts into the genome.
It's based on the first part of this research paper:
The cost of information acquisition by natural selection
Ryan Seamus McGee, Olivia Kosterlitz, Artem Kaznatcheev, Benjamin Kerr, Carl T. Bergstrom
bioRxiv 2022.07.02.498577; doi: https://doi.org/10.1101/2022.07.02.498577
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Chem Service is Committed to Quality and to Our Customers
Chem Service provides Certificates of Analysis for our Standards Grade pesticide and metabolite stan-
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9001 Quality System Requirements. Our neat chemical certification policy states that purity and identifi-
cation must be established independently by performing three or more (when feasible) separate analyses
before we certify any of our neat products. More than 95% of our neat Standards Grade materials have
a certified purity of 98.0% or greater. Our pesticide standards, whether sold as neat products or as solu-
tions, are certified for purity, identity, stability and are traceable by lot.
Chem Service is recognized worldwide for the quality of the materials we provide. We have maintained
ISO Guide 34, ISO 17025 accreditation and ISO 9001 certification. This stringent level of compliance
applies to all of our internal design, development, production, distribution, and servicing of organic neat
and synthetic reference materials which, we supply to our customers.
Our internal quality program utilizes our company's years of experience in providing laboratories with
highly purified materials for reference standards. Our experience has enabled us to identify "problem"
materials that need special attention. For example, any potential peroxide former is tested frequently for
peroxide formation to assure both purity and safety. Moreover, with our expertise in analyte compatiblity,
solubiltiy, solution stability and analysis, Chem Service is uniquely qualified to provide your customized
soutions and mixture standards.
Our on-going stability testing program for Standards Grade materials has additional benefits for our
customers. We will supply neat standards only when they have a minimum of the shelf life remaining
on their lot certification. If our stability testing shows the material has a purity or stability problem which
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MakingDilutionsAs one can see, these calculations can be manipulated to allow you to achieve any final volume or concentration you need.
They can also be used to convert to other types of concentrations (weight/weight or volume/volume).
It is often necessary to make a dilution of your chemicals in order to analyze them. Dilutions can be made in one of three
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expressed as 1ppm = 1ug/g, for weight/volume, 1ppm = 1ug/mL, and for volume/volume, 1ppm = 1ul/L. Chem Service
supplies most of their solutions at a concentration of 0.1mg/mL (100ug/mL or 100ppm). In order to make a solution at
a concentration of 100ppm, starting with a pure chemical, you need to know your final volume. Then if the material is a
solid, the calculations are:
0.1mg/mL (final concentration) x 100mL (final volume) = weight of chemical needed (10mg)
FC x FV = W
0.1mg/mL (final conc.) x 100mL (final volume)0.1mg/mL (final conc.) x 100mL (final volume) = volume (number of ul) of chemical needed density (mg/ul)
FC x FV = V
d
If the material is a liquid, it is usually easier to convert to a liquid measurement (i.e. ul), for handling purposes. Therefore,
the density is needed and the calculations are:
0.1mg/mL (initial concentration) x 1mL (volume injected)0.1mg/mL (initial concentration) x 1mL (volume injected) x 1000ug1000ug (conversion factor) = 1ug/mL (final concentration)
100mL (final volume) 1mg
IC x VI x CF = FC
FV
If you need to make a further dilution from a prepared solution, the calculations would be basically the same format. For
example, to dilute 100ppm to 1ppm, take a 1mL aliquot of 0.1mg/mL (100ppm) solution, and dilute to your final volume
(100mL).
The above formula gives the final concentration for the solution. The formula to obtain the volume to inject in order to make
the dilution for this final volume is:
FC x FV x CF = VI
IC
LEGEND
FC = final concentration IC = initial concentration
FV = final volumeFV = final volumeFV VI = volume injected
W = weight neededW = weight neededW CF = conversion factor
d = density V = volume neededV = volume neededV
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Acetic acid
Acetone
Acetonitrile
Benzene Legend
2-Butanol
Butyl alcohol Miscible
tert-Butylmethyl ether (MTBE)
Carbon tetrachloride Immiscible
Chloroform
Cyclohexane
Cyclopentane Read down column and over
Dichloroethane for solvent miscibility
N,N-Dimethylformamide (DMF)
1,4-Dioxane Acetonitrile
Dipropyl ether
Ethyl acetate Cyclohexane
Ethyl alcohol are immiscible
Ethyl ether
n-Heptane
n-Hexane
Isooctane
Isopropyl alcohol
Methanol
Methylene chloride
Methyl sulfoxide (DMSO)
n-Pentane
1,1,2,2-Tetrachloroethane
Tetrahydrofuran (THF)
Toluene
Trichloroethane
Water
Xylene
SolventMiscibilityTable
8. 7
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CHEM SERVICE
PO BOX 599, WEST CHESTER, PA 19381 800-452-9994
N-11971-100MG Exp 11/30/2018
Fipronil
Lot: 5848400 Purity: 99.5%
TOXIC-HAZARDOUS TO THE ENVIRONMENT
WARNING! READ your SDS before HANDLING chemical. Full Label information is provided on the outside package.
NO GHS
SYMBOL
a
c
d e
f
b
a Part number
b Expiration Date
c Product Description
d Lot Number
e Purity
f Hazard Warning
Neat Standard Label
CHEM SERVICE
PO BOX 599, WEST CHESTER, PA 19381 800-452-9994
S-13189A1-1ML Exp 1/31/2019
S-Hydroprene Solution
Lot: 5827200
100ug/ml In Acetonitrile
FLAMMABLE-POISON-LACHRYMATOR
WARNING! READ your SDS before HANDLING chemical. Full Label information is provided on the outside package.
NO GHS
SYMBOL
a
d
e
f
b
c
a Part number
b Expiration Date
c Product Description
d Lot Number
e Solvent and Concentration
f Hazard Warning
Solution and Mixture Standard Label
Code Solvent
A Acetonitrile
B Acetone
C Benzene
D Carbon Disulfide
E Cyclohexane
F Water
G Ethanol
H Ethyl Acetate
J Hexane
K Isooctane
L Isopropanol
M Methanol
N Methanol:Water
P n-Nonane
Q n-Pentane
R P&T Methanol
S Propanol
T t-Butylmethyl ether
U Toluene
Code Solvent
V Transformer Oil
W Methanol:Acetonitrile (80:20)
X Methylene Chloride
Y Isooctane:Acetone (90:10)
Z Acetonitrile:Acetone (90:10)
AA Acetonitrile:Water (75:25)
AB Benzene:MeCl2:Acetonitrile (40:40:20)
AC Toluene:Hexane (50:50)
AD CH2Cl2:Benzene (50:50)
AE Hexane:Methylene chloride (90:10)
AF Hexane:Acetone (90:10)
AG Hexane:Acetone (80:20)
AH Methanol:Acetonitrile (50:50)
AJ Methylene chloride:Benzene (50:50)
AK Methanol:Acetone (50:50)
AL Acetone:Toluene (50:50)
AM 2-Methoxyethanol
AN Dimethyl sufoxide
AP Methanol:Water (90:10)
Code Concentration
0 50 ug/ml
1 100 ug/ml
2 200 ug/ml
3 500 ug/ml
4 1000 ug/ml
5 2000 ug/ml
6 2500 ug/ml
7 5000 ug/ml
8 10000 ug/ml
9 20000 ug/ml
10 10 ug/ml
11 250 ug/ml
12 4000 ug/ml
13 1970 ug/ml
14 3000 ug/ml
15 400 ug/ml
16 1300 ug/ml
17 1770 ug/ml
18 25 ug/ml
19 20 ug/ml
20 30 ug/ml
Solvent and Concentration Key
9. Pesticide and Metabolite Standards
Alphabetical Listing
N-11984-100MG 100MGAastar(TM) 70124-77-5
a Chem Service Product Description
b Chemical Abstracts Registry Number
c Part Number
d Size
a b c d